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Emily R. Legan
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Journal Articles

Conformational activation and inhibition of von Willebrand factor by targeting its autoinhibitory module

Nicholas A. Arce, Zoe Markham-Lee, Qian Liang, Shabir Najmudin, Emily R. Legan, Gabrielle Dean, Ally J. Su, Moriah S. Wilson, Robert F. Sidonio, Pete Lollar, Jonas Emsley, Renhao Li
Journal: Blood
Blood (2024) 143 (19): 1992–2004.
https://doi.org/10.1182/blood.2023022038
Published: 2024
Includes: Supplemental data
Journal Articles

Type 2B von Willebrand disease mutations differentially perturb autoinhibition of the A1 domain

Emily R. Legan, Yi Liu, Nicholas A. Arce, Ernest T. Parker, Pete Lollar, X. Frank Zhang, Renhao Li
Journal: Blood
Blood (2023) 141 (10): 1221–1232.
https://doi.org/10.1182/blood.2022017239
Published: 2023
Includes: Supplemental data