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Elie Traer, MD PhD
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Journal Articles

Maturing Clinical Profile of IMGN779, a Next-Generation CD33-Targeting Antibody-Drug Conjugate, in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Jorge E. Cortes, MD, Daniel J. DeAngelo, MD, Harry P. Erba, MDPhD, Elie Traer, MD PhD, Nikolaos Papadantonakis, MDPhDMSc, Cecilia Arana-Yi, MD, William Blum, MD, Callum M. Sloss, PhD, Kerry Culm-Merdek, Patrick A. Zweidler-McKay, MD PhD, Eunice S. Wang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 26.
https://doi.org/10.1182/blood-2018-99-112891
Published: 2018
Journal Articles

IMGN779, a Next-Generation CD33-Targeting Antibody-Drug Conjugate (ADC) Demonstrates Initial Antileukemia Activity in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Jorge E. Cortes, MD, Elie Traer, MD PhD, Eunice S. Wang, MD, Harry P. Erba, MD PhD, William Blum, MD, Cecilia Arana-Yi, MD, Callum M. Sloss, Kerry Culm-Merdek, Jeanette Towles, Patrick A. Zweidler-McKay, MDPhD, Daniel J. DeAngelo, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1312.
https://doi.org/10.1182/blood.V130.Suppl_1.1312.1312
Published: 2017
Journal Articles

Identification of Effective Combinations of Targeted Drugs for DNMT3A and NPM1 Mutated Acute Myeloid Leukemia

Stephen E Kurtz, PhD, Christopher A. Eide, Andy Kaempf, Samantha L Savage, Anna M. Reister Schultz, Beth Wilmot, PhD, Shannon Mcweeney, PhD, Motomi Mori, PhD, Elie Traer, MD PhD, Brian J. Druker, MD, Jeffrey W. Tyner, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2068.
https://doi.org/10.1182/blood.V130.Suppl_1.2068.2068
Published: 2017
Journal Articles

Ivosidenib (AG-120) in Mutant IDH1 AML and Advanced Hematologic Malignancies: Results of a Phase 1 Dose Escalation and Expansion Study

Courtney D. DiNardo, MDMSc, Stephane De Botton, Eytan M. Stein, MD, Gail J. Roboz, MD, Alice S. Mims, MD MSCR, Daniel A. Pollyea, MD, Ronan T. Swords, MD PhD FRCPI, FRCPath, Jessica K. Altman, MD, Robert H. Collins, MD, Gabriel N. Mannis, MD, Geoffrey L. Uy, MD, Will Donnellan, MD, Arnaud Pigneux, MD PhD, Amir T. Fathi, MD MD BS, Anthony S. Stein, MD, Harry P. Erba, MD PhD, Gabrielle T. Prince, MD, James M. Foran, MD, Elie Traer, MD PhD, Robert K. Stuart, MD, Martha L. Arellano, MD, James L. Slack, MD, Mikkael A. Sekeres, MD MS, Katharine Yen, Stephanie M. Kapsalis, Hua Liu, Meredith Goldwasser, Sam Agresta, MD, Eyal C. Attar, MD, Martin S. Tallman, MD, Richard M. Stone, MD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 725.
https://doi.org/10.1182/blood.V130.Suppl_1.725.725
Published: 2017
Journal Articles

Marrow Stromal Cells Secrete FGF2 in Exosomes, Providing Paracrine Protection for Leukemia Cells from Kinase Inhibitors

Elie Traer, MD PhD, Brian J. Druker, MD, Jakki Martinez, Nathalie Javidi-Sharifi, Isabel English, BA, Anupriya Agarwal, PhD, Jennifer Dunlap, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 306.
https://doi.org/10.1182/blood.V130.Suppl_1.306.306
Published: 2017
Journal Articles

FGF2-Containing Exosomes Secreted from Bone Marrow Stromal Cells Protect Leukemia Cells from Tyrosine Kinase Inhibitors

Jacqueline Martinez, MS, Nathalie Javidi-Sharifi, Isabel English, Shelton A. Viola, MD, Danielle Jorgens, PhD, Brian J. Druker, MD, Elie Traer, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2465.
https://doi.org/10.1182/blood.V126.23.2465.2465
Published: 2015
Journal Articles

Mutations Modifying Risk in NPM1+ AML

Jessica Leonard, MD, Jennifer Dunlap, MD, Tanaya L Neff, Andrea Warrick, Fei Yang, Richard D. Press, MD PhD, Brian J. Druker, MD, Elie Traer, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 2592.
https://doi.org/10.1182/blood.V126.23.2592.2592
Published: 2015
Journal Articles

Colony Stimulating Factor 1 Receptor (CSF1R) As a Potential Novel Therapeutic Target in CLL

Tyler Sweeney, Stephen E Spurgeon, MD, Jeffrey W. Tyner, PhD, Anupriya Agarwal, PhD, Hibery Ho, Elie Traer, MD PhD, Patrice Lee, PhD, David Chantry, PhD, Brian J. Druker, MD, Marc Loriaux, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4439.
https://doi.org/10.1182/blood.V126.23.4439.4439
Published: 2015
Journal Articles

CSF1R Inhibition Targets AML Cells By Depleting Supportive Microenvironmental Signal from CD14+ Monocytes

David K Edwards, V, B.A., B.S., Angela Rofelty, BS, Anupriya Agarwal, PhD, Stephen E Kurtz, PhD, Elie Traer, MD PhD, Patrice Lee, PhD, David Chantry, PhD, Marc Loriaux, MD PhD, Brian J. Druker, MD, Shannon K. McWeeney, PhD, Jeffrey W. Tyner, PhD
Journal: Blood
Blood (2015) 126 (23): 3824.
https://doi.org/10.1182/blood.V126.23.3824.3824
Published: 2015
Journal Articles

Identification of Effective Targeted Drug Combinations Using Functional Ex Vivo Screening of Primary Patient Specimens

Stephen E Kurtz, PhD, Elie Traer, MD PhD, Jakki Martinez, Andrew Park, Jake Wagner, Ravi Pandya, PhD, William Bolosky, PhD, Brian J. Druker, MD, Jeffrey W. Tyner, PhD
Journal: Blood
Blood (2015) 126 (23): 865.
https://doi.org/10.1182/blood.V126.23.865.865
Published: 2015
Journal Articles

The Pro-Inflammatory Cytokine Interleukin-1 Is Essential for Clonal Expansion and Disease Progression in Acute Myeloid Leukemia

Alyssa Carey, BS, Megan M Cleary, B.S., B.A., David K Edwards, V, B.A., B.S., Christopher A. Eide, Elie Traer, MD PhD, Shannon K. McWeeney, PhD, Jeffrey W. Tyner, PhD, Grover C. Bagby, MD, Brian J. Druker, MD, Anupriya Agarwal, PhD
Journal: Blood
Blood (2015) 126 (23): 866.
https://doi.org/10.1182/blood.V126.23.866.866
Published: 2015
Journal Articles

Targeted Suppression of Interleukin-1 Signaling Attenuates Leukemic Cellular Growth and Disease Progression in Primary Human Cells and Murine Models of Acute Myeloid leukemia­­

Alyssa Carey, B.A., David Edwards, B.A., B.S., Christopher A. Eide, Elie Traer, MD, PhD, Jeffrey W. Tyner, Grover C. Bagby, MD MACP, Brian J. Druker, Anupriya Agarwal
Journal: Blood
Blood (2014) 124 (21): 702.
https://doi.org/10.1182/blood.V124.21.702.702
Published: 2014
Journal Articles

FGF2 Promotes Resistance To Quizartinib In Vitro, and FGF2 Increases In The Marrow Of Patients Prior To Resistance

Elie Traer, MD, PhD, Nathalie Javidi-Sharifi, Anupriya Agarwal, Jennifer B Dunlap, MD, Isabel English, Jacqueline Martinez, Tibor J. Kovacsovics, MD, Jeffrey W. Tyner, Melissa Wong, PhD, Brian J. Druker
Journal: Blood
Blood (2013) 122 (21): 2541.
https://doi.org/10.1182/blood.V122.21.2541.2541
Published: 2013
Journal Articles

FGF2 Mediates Resistance In CML Patients In The Absence Of Kinase Domain Mutations, and Resistance Is Overcome By Ponatinib

Elie Traer, MD, PhD, Nathalie Javidi-Sharifi, Anupriya Agarwal, Jennifer B Dunlap, MD, Isabel English, Jacqueline Martinez, Jeffrey W. Tyner, Melissa Wong, PhD, Brian J. Druker
Journal: Blood
Blood (2013) 122 (21): 3983.
https://doi.org/10.1182/blood.V122.21.3983.3983
Published: 2013
Journal Articles

Intrinsic and Extrinsic Survival Signals Converge on STAT3 As a Critical Mediator of BCR-ABL-Independent Tyrosine Kinase Inhibitor Resistance,

Anna M Eiring, PhD, Ira L Kraft, BS, David J Anderson, BS, Elie Traer, MD, PhD, Qian Yu, BS, Jamshid Khorashad, MD, PhD, Thomas O'Hare, Michael W. Deininger
Journal: Blood
Blood (2011) 118 (21): 3742.
https://doi.org/10.1182/blood.V118.21.3742.3742
Published: 2011
Journal Articles

JAK2-Mediated Extrinsic Survival of CML Stem Cells: Exploring the Potential Combination of BCR-ABL and JAK2 Inhibitors In Vivo

Elie Traer, MD, PhD, Ryan MacKenzie, Jennifer Snead, PhD, Brian J Druker, MD, Michael W Deininger, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 199.
https://doi.org/10.1182/blood.V116.21.199.199
Published: 2010