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Edwin R. Chilvers
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Journal Articles

Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish

A. A. Roger Thompson, Philip M. Elks, Helen M. Marriott, Suttida Eamsamarng, Kathryn R. Higgins, Amy Lewis, Lynne Williams, Selina Parmar, Gary Shaw, Emmet E. McGrath, Federico Formenti, Fredericus J. Van Eeden, Vuokko L. Kinnula, Christopher W. Pugh, Ian Sabroe, David H. Dockrell, Edwin R. Chilvers, Peter A. Robbins, Melanie J. Percy, M. Celeste Simon, Randall S. Johnson, Stephen A. Renshaw, Moira K. B. Whyte, Sarah R. Walmsley
Journal: Blood
Blood (2014) 123 (3): 366–376.
https://doi.org/10.1182/blood-2013-05-500207
Published: 2014
Includes: Supplemental data
Journal Articles

Use of 111-Indium–labeled autologous eosinophils to establish the in vivo kinetics of human eosinophils in healthy subjects

Brief Report
Neda Farahi, Nanak R. Singh, Sarah Heard, Chrystalla Loutsios, Charlotte Summers, Chandra K. Solanki, Kishor Solanki, Kottekkattu K. Balan, Prina Ruparelia, A. Michael Peters, Alison M. Condliffe, Edwin R. Chilvers
Journal: Blood
Blood (2012) 120 (19): 4068–4071.
https://doi.org/10.1182/blood-2012-07-443424
Published: 2012
Includes: Supplemental data
Journal Articles

Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis

Clinical Trials & Observations
Sarah R. Walmsley, Andrew S. Cowburn, Menna R. Clatworthy, Nicholas W. Morrell, Emma C. Roper, Vanessa Singleton, Patrick Maxwell, Moira K. B. Whyte, Edwin R. Chilvers
Journal: Blood
Blood (2006) 108 (9): 3176–3178.
https://doi.org/10.1182/blood-2006-04-018796
Published: 2006
Journal Articles

Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils

Alison M. Condliffe, Keith Davidson, Karen E. Anderson, Chris D. Ellson, Tom Crabbe, Klaus Okkenhaug, Bart Vanhaesebroeck, Martin Turner, Louise Webb, Matthias P. Wymann, Emilio Hirsch, Thomas Ruckle, Montserrat Camps, Christian Rommel, Shaun P. Jackson, Edwin R. Chilvers, Len R. Stephens, Phillip T. Hawkins
Journal: Blood
Blood (2005) 106 (4): 1432–1440.
https://doi.org/10.1182/blood-2005-03-0944
Published: 2005
Includes: Supplemental data
Journal Articles

z-VAD-fmk augmentation of TNFα-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species

Brief Report
Andrew S. Cowburn, Jessica F. White, John Deighton, Sarah R. Walmsley, Edwin R. Chilvers
Journal: Blood
Blood (2005) 105 (7): 2970–2972.
https://doi.org/10.1182/blood-2004-07-2870
Published: 2005
Journal Articles

Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis

Katy I. Mecklenburgh, Sarah R. Walmsley, Andrew S. Cowburn, Michael Wiesener, Benjamin J. Reed, Paul D. Upton, John Deighton, Andrew P. Greening, Edwin R. Chilvers
Journal: Blood
Blood (2002) 100 (8): 3008–3016.
https://doi.org/10.1182/blood-2002-02-0454
Published: 2002
Journal Articles

Role of PI3-kinase–dependent Bad phosphorylation and altered transcription in cytokine-mediated neutrophil survival

Andrew S. Cowburn, Karen A. Cadwallader, Benjamin J. Reed, Neda Farahi, Edwin R. Chilvers
Journal: Blood
Blood (2002) 100 (7): 2607–2616.
https://doi.org/10.1182/blood-2001-11-0122
Published: 2002
Journal Articles

Regulation of Neutrophil Apoptosis by Tumor Necrosis Factor-α: Requirement for TNFR55 and TNFR75 for Induction of Apoptosis In Vitro

Joanna Murray, Jeffrey A.J. Barbara, Sarah A. Dunkley, Angel F. Lopez, Xaveer Van Ostade, Alison M. Condliffe, Ian Dransfield, Christopher Haslett, Edwin R. Chilvers
Journal: Blood
Blood (1997) 90 (7): 2772–2783.
https://doi.org/10.1182/blood.V90.7.2772
Published: 1997