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Journal Articles

Effector Differentiation and Exhaustion Attenuate on-Target, Off-Tumor Toxicity of CD24 CAR T Cells

Free
Alexander P. Boardman, Adhithi Rajagopalan, Sophia Chen, Brandon Ng, Jacob Fischman, Alyssa Massa, Harold K Elias, Dylan Manuele, Mohamed I. Atmane, Ileana Miranda, Scott E. James, Marcel R.M. van den Brink
Journal: Blood
Blood (2024) 144 (Supplement 1): 2030.
https://doi.org/10.1182/blood-2024-202499
Published: 2024
Journal Articles

Regulatory T Cell Derived Trefoil Factor 1 Drives Thymic Regeneration in Allogeneic Hematopoietic Cell Transplantation

Free
Jonah Pierce, Brianna Gipson, Lucia Serrano-Marin, Kimon V Argyropoulos, Susan DeWolf, Scott E. James, Manpreet Kaur, Anastasia Kousa, Chi L Nguyen, Adhithi Rajagopalan, Kristen Victor, Kenyon Weis, Andri Leo L Lemarquis, Marcel R.M. van den Brink
Journal: Blood
Blood (2024) 144 (Supplement 1): 2010.
https://doi.org/10.1182/blood-2024-202774
Published: 2024
Journal Articles

Dual-Vector-Transduction with Single-Step Magnetic Selection (Zip-sort) Increases Transgenic Payloads to Enhance CAR T Cell Activity

Free
Scott E. James, Sophia Chen, Brandon Ng, Jacob Fischman, Lorenz Jahn, Alexander P. Boardman, Adhithi Rajagopalan, Harold K Elias, Alyssa R Massa, Dylan Manuele, Katherine Nichols, Amina Lazrak, Nicole Lee, Aoife Doto, Alexander McMarland, Angelina Petrichenko, John Everett, Frederic Bushman, Teng Fei, Anastasia Kousa, Andri Leo L Lemarquis, Susan DeWolf, Jonathan U. Peled, Santosha A. Vardhana, Christopher A. Klebanoff, Marcel R.M. van den Brink
Journal: Blood
Blood (2024) 144 (Supplement 1): 501.
https://doi.org/10.1182/blood-2024-208357
Published: 2024
Journal Articles

IL-18-secreting multiantigen targeting CAR T cells eliminate antigen-low myeloma in an immunocompetent mouse model

Available to Purchase
Brandon D. Ng, Adhithi Rajagopalan, Anastasia I. Kousa, Jacob S. Fischman, Sophia Chen, Alyssa Massa, Harold K. Elias, Dylan Manuele, Michael Galiano, Andri L. Lemarquis, Alexander P. Boardman, Susan DeWolf, Jonah Pierce, Bjarne Bogen, Scott E. James, Marcel R. M. van den Brink
Journal: Blood
Blood (2024) 144 (2): 171–186.
https://doi.org/10.1182/blood.2023022293
Published: 2024
Includes: Supplemental data
Journal Articles

CCR1-Targeting CAR T Cells for Acute Myeloid Leukemia

Free
Sophia Chen, Alexander P. Boardman, Scott E. James, Marcel R.M. van den Brink
Journal: Blood
Blood (2023) 142 (Supplement 1): 4808.
https://doi.org/10.1182/blood-2023-184464
Published: 2023
Journal Articles

C-CBL Is a Critical Negative Regulator of Megakaryopoesis

Free
Sebastian J. Saur, MD, Melanie Märklin, M. Sc., Alexandra Poljak, B. Sc., Manuela Ganser, B. Sc., David E. James, PhD, Kyle Hoehn, PhD, Lothar Kanz, MD, Hans-Georg Kopp, MD, Martin R. Müller, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1581.
https://doi.org/10.1182/blood.V124.21.1581.1581
Published: 2014
Journal Articles

Ras-induced reactive oxygen species promote growth factor–independent proliferation in human CD34 + hematopoietic progenitor cells

Free
Paul S. Hole, Lorna Pearn, Amanda J. Tonks, Philip E. James, Alan K. Burnett, Richard L. Darley, Alex Tonks
Journal: Blood
Blood (2010) 115 (6): 1238–1246.
https://doi.org/10.1182/blood-2009-06-222869
Published: 2010
Includes: Supplemental data
Journal Articles

Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice

Free
Scott E. James, Nural N. Orgun, Thomas F. Tedder, Mark J. Shlomchik, Michael C. Jensen, Yukang Lin, Philip D. Greenberg, Oliver W. Press
Journal: Blood
Blood (2009) 114 (27): 5454–5463.
https://doi.org/10.1182/blood-2009-08-232967
Published: 2009
Includes: Supplemental data
Journal Articles

Ras Promotes Production of Reactive Oxygen Species in Normal Human CD34 + Cells: Role in Promoting Cell Survival and Protein Phosphorylation

Free
Paul S Hole, BA, Lorna Pearn, Philip E James, PhD, Alan Burnett, MD, Richard L Darley, PhD, Alex Tonks, PhD
Journal: Blood
Blood (2008) 112 (11): 3797.
https://doi.org/10.1182/blood.V112.11.3797.3797
Published: 2008
Journal Articles

Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

Free
Clinical Trials & Observations
Brian G. Till, Michael C. Jensen, Jinjuan Wang, Eric Y. Chen, Brent L. Wood, Harvey A. Greisman, Xiaojun Qian, Scott E. James, Andrew Raubitschek, Stephen J. Forman, Ajay K. Gopal, John M. Pagel, Catherine G. Lindgren, Philip D. Greenberg, Stanley R. Riddell, Oliver W. Press
Journal: Blood
Blood (2008) 112 (6): 2261–2271.
https://doi.org/10.1182/blood-2007-12-128843
Published: 2008
Includes: Supplemental data
Journal Articles

Molecular Heterogeneity in Recombinant Erythropoietin Using Surface Enhanced Laser Induced Desorption Ionization (SELDI). Clinical Implications.

Free
E. James, BS, J. Maddineni, BS, J. Fareed, PhD, M. Florian-Kujawski, BS, F. Baltasar, BS, W. Jeske, PhD, D. Hoppensteadt, PhD, M. Tobu, MD, M. Demir, MD, O. Iqbal, MD, V. Bansal, MD
Journal: Blood
Blood (2005) 106 (11): 3557.
https://doi.org/10.1182/blood.V106.11.3557.3557
Published: 2005