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Donald A Simone
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Journal Articles

Cold exposure induces vaso-occlusion and pain in sickle mice that depend on complement activation

Zalaya K. Ivy, John D. Belcher, Iryna A. Khasabova, Chunsheng Chen, Joseph P. Juliette, Fuad Abdulla, Conglin Ruan, Kaje Allen, Julia Nguyen, Victoria M. Rogness, Joan D. Beckman, Sergey G. Khasabov, Kalpna Gupta, Ronald P. Taylor, Donald A. Simone, Gregory M. Vercellotti
Journal: Blood
Blood (2023) 142 (22): 1918–1927.
https://doi.org/10.1182/blood.2022019282
Published: 2023
Includes: Supplemental data
Journal Articles

A model of painful vaso-occlusive crisis in mice with sickle cell disease

Iryna I. Khasabova, Joseph Juliette, Victoria M. Rogness, Sergey G. Khasabov, Mikhail Y. Golovko, Svetlana A. Golovko, Stacy Kiven, Kalpna Gupta, John D. Belcher, Gregory M. Vercellotti, Virginia S. Seybold, Donald A. Simone
Journal: Blood
Blood (2022) 140 (16): 1826–1830.
https://doi.org/10.1182/blood.2022017309
Published: 2022
Journal Articles

Sensitization of nociceptors by prostaglandin E 2 –glycerol contributes to hyperalgesia in mice with sickle cell disease

Iryna A. Khasabova, Megan Uhelski, Sergey G. Khasabov, Kalpna Gupta, Virginia S. Seybold, Donald A. Simone
Journal: Blood
Blood (2019) 133 (18): 1989–1998.
https://doi.org/10.1182/blood-2018-11-884346
Published: 2019
Journal Articles

Targeting Putative Mu Opioid/Chemokine Receptor Type 5 Heteromers Potently Attenuates Nociception in a Murine Model of Sickle Cell Disease

Giuseppe Cataldo, PhD, Mary M. Lunzer, MA, Donald A. Simone, PhD, Eyup Akgün, PhD, John D. Belcher, PhD, Gregory M Vercellotti, Philip S. Portoghese, PhD
Journal: Blood
Blood (2015) 126 (23): 277.
https://doi.org/10.1182/blood.V126.23.277.277
Published: 2015
Journal Articles

Heme Induced Spinal Microglial Cell Activation By TLR4 and Endoplasmic Reticulum Stress in Sickle Mice

Jinny Paul, PhD, Jianxun Lei, PhD, Ritu Jha, MS, Julia Nguyen, BS, Donald A Simone, PhD, Kalpna Gupta, PhD
Journal: Blood
Blood (2014) 124 (21): 452.
https://doi.org/10.1182/blood.V124.21.452.452
Published: 2014
Journal Articles

Mast cell activation contributes to sickle cell pathobiology and pain in mice

Lucile Vincent, Derek Vang, Julia Nguyen, Mihir Gupta, Kathryn Luk, Marna E. Ericson, Donald A. Simone, Kalpna Gupta
Journal: Blood
Blood (2013) 122 (11): 1853–1862.
https://doi.org/10.1182/blood-2013-04-498105
Published: 2013
Includes: Supplemental data
Journal Articles

Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids

Divyanshoo R. Kohli, Yunfang Li, Sergey G. Khasabov, Pankaj Gupta, Lois J. Kehl, Marna E. Ericson, Julia Nguyen, Vinita Gupta, Robert P. Hebbel, Donald A. Simone, Kalpna Gupta
Journal: Blood
Blood (2010) 116 (3): 456–465.
https://doi.org/10.1182/blood-2010-01-260372
Published: 2010
Includes: Supplemental data
Journal Articles

Cannabinoids as Analgesics for Pain in Sickle Cell Disease.

Divyanshoo Rai Kohli, Yunfang Li, MD, Sergey G Khasabov, Marna E Ericson, Pankaj Gupta, MD, Donald A Simone, Robert P Hebbel, MD, Kalpna Gupta, PhD
Journal: Blood
Blood (2009) 114 (22): 822.
https://doi.org/10.1182/blood.V114.22.822.822
Published: 2009