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Journal Articles

With Equal Access, African Americans with Non-del17p Multiple Myeloma Have Superior Overall Survival, but del17p Still Carries Poor Prognosis across Race: A VA Study

Anusha Munjuluri, MSc, Nathanael Fillmore, PhD, Diana Cirstea, MD, Hassan Yameen, MD, Sarvari Venkata Yellapragada, MD, Ifeorah Chizoba, MPH, Nhan Do, MD, Mary Brophy, MD MPH, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 4388.

https://doi.org/10.1182/blood-2019-131247

Published: 2019

Journal Articles

Treatment Disparities in Minority Groups with Multiple Myeloma at a Large Safety-Net Hospital

Michael Dennis, MD, Diana Cirstea, MD, Asaf Maoz, MD, Adam Lerner, MD, Ami K. Patel, MD, Shayna Sarosiek, MD

Blood (2018) 132 (Supplement 1): 4864.

https://doi.org/10.1182/blood-2018-99-118472

Published: 2018

Journal Articles

Opioid Use Is NOT Associated with in-Hospital Mortality Among Patients with Sickle CELL Disease in the United States: Findings from the National Inpatient Sample

Oladimeji Akinola Akinboro, MBBS, Stanley Nwabudike, MD, Camille Edwards, MD, Diana Cirstea, MD, Nana Oduraa Addo-Tabiri, MD PhD, Michael Voisine, MD, Hassan Yameen, MD, Adetola A. Kassim, MD MS

Blood (2018) 132 (Supplement 1): 315.

https://doi.org/10.1182/blood-2018-99-115573

Published: 2018

Journal Articles

TAS-117, a Novel Selective Akt Inhibitor Demonstrates Significant Growth Inhibition in Multiple Myeloma Cells in Vitro and in Vivo

Naoya Mimura, Hiroto Ohguchi, Diana Cirstea, MD, Francesca Cottini, Gullu Topal Gorgun, PhD, Jiro Minami, Rikio Suzuki, Toshiyasu Shimomura, PhD, Teruhiro Utsugi, PhD, Teru Hideshima, MD, PhD, Kenneth C. Anderson, MD

Blood (2012) 120 (21): 942.

https://doi.org/10.1182/blood.V120.21.942.942

Published: 2012

Journal Articles

Selective HDAC6 Inhibition Via ACY-1215, Either Alone or in Combination with Bortezomib, Restores Osteoblast Function and Suppresses Osteoclast Differentiation in Multiple Myeloma

Loredana Santo, MD, Teru Hideshima, MD, PhD, Andrew L. Kung, MD, PhD, Jen-Chieh Tseng, PhD, David Tamang, PhD, Min Yang, PhD, Matthew Jarpe, PhD, John H. van Duzer, PhD, Ralph Mazitschek, PhD, Diana Cirstea, MD, Homare Eda, MD, PhD, Tyler A. Scullen, BA, Scott Rodig, MD, PhD, Miriam Canavese, PhD, James Bradner, MD, Kenneth C Anderson, MD, Simon Jones, PhD, Noopur S. Raje, MD

Blood (2011) 118 (21): 2908.

https://doi.org/10.1182/blood.V118.21.2908.2908

Published: 2011

Journal Articles

DEPTOR Is a Regulator of Response to mTOR Kinase Inhibitors in Multiple Myeloma

Diana Cirstea, MD, Teru Hideshima, MD, PhD, Loredana Santo, MD, Homare Eda, MD, PhD, Miriam Canavese, PhD, Tyler A. Scullen, BA, Anuj K. Mahindra, MD, Gullu Gorgun, PhD, Yiguo Hu, MD, PhD, Naoya Mimura, MD, PhD, Claire Fabre, MD, PhD, Jiro Minami, MD, PhD, Hiroto Ohguchi, MD, PhD, Kenneth C. Anderson, MD, Sylvie M Guichard, PharmD, PhD, Noopur S. Raje, MD

Blood (2011) 118 (21): 2916.

https://doi.org/10.1182/blood.V118.21.2916.2916

Published: 2011

Journal Articles

Immunomodulatory Effects of Histone Deacetylase 6 Inhibition in Suppressor Immune Cells in Multiple Myeloma

Gullu Gorgun, PhD, Teru Hideshima, MD, PhD, Noopur S. Raje, MD, Naoya Mimura, MD, PhD, James E. Bradner, MD, Diana Cirstea, MD, Loredana Santo, MD, Yu-Tzu Tai, PhD, Michael Sellitto, Yiguo Hu, PhD, Claire Fabre, MD, PhD, Hiroto Ohguchi, MD, PhD, Jiro Minami, MD, PhD, Paul G. Richardson, MD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD

Blood (2011) 118 (21): 128.

https://doi.org/10.1182/blood.V118.21.128.128

Published: 2011

Journal Articles

Lenalidomide In Combination with the Activin Receptor Type II Murine Fc Protein RAP-011: Preclinical Rationale for a Novel Anti-Myeloma Strategy

Sonia Vallet, MD, Kishan Patel, Diana Cirstea, MD, Katie Luly, Samantha Pozzi, MD, Loredana Santo, MD, Homare Eda, MD, Jasbir Seehra, Anuj Mahindra, MD, David T. Scadden, MD, Noopur Raje, MD

Blood (2010) 116 (21): 4075.

https://doi.org/10.1182/blood.V116.21.4075.4075

Published: 2010

Journal Articles

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor with Potent Activity Against Aurora Kinase and STAT3 In Combination with Lenalidomide Results In Synergistic Anti-Myeloma Activity

Loredana Santo, MD, Teru Hideshima, MD, PhD, Diana Cirstea, MD, Madhavi L Bandi, PhD, Erik A Nelson, PhD, Hiroshi Ikeda, MD, Sonia Vallet, MD, Samantha Pozzi, MD, Kishan Patel, Gullu Gorgun, PhD, Naoya Mimura, MD, Claire Fabre, MD, Yiguo Hu, PhD, Dharminder Chauhan, PhD, Matthew S Squires, PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2010) 116 (21): 2994.

https://doi.org/10.1182/blood.V116.21.2994.2994

Published: 2010

Journal Articles

Molecular Sequaele of Activin A-Dependent Osteoblast Inhibition in Myeloma.

Blood (2009) 114 (22): 1789.

https://doi.org/10.1182/blood.V114.22.1789.1789

Published: 2009

Journal Articles

Bcl6 as a Novel Therapeutic Target in Multiple Myeloma (MM).

Teru Hideshima, M.D., Ph.D., Constantine S. Mitsiades, MD, PhD, Hiroshi Ikeda, MD, PhD, Dharminder Chauhan, PhD, Noopur Raje, M.D., Gullu Gorgun, PhD, Mariateresa Fulciniti, PhD, Diana Cirstea, MD, Giulia Perron, MD, Loredana Santo, M.D., Ayaka Hideshima, Klaus Podar, MD, MSc, PhD, Nikhil C. Munshi, MD, Paul Richardson, M.D., Ph.D., Daniel R. Carrasco, MD, PhD, Kenneth C. Anderson, MD

Blood (2009) 114 (22): 295.

https://doi.org/10.1182/blood.V114.22.295.295

Published: 2009

Journal Articles

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor Induces Antimyeloma Activity Via Potent Aurora Kinase and STAT3 Inhibition.

Loredana Santo, M.D., Teru Hideshima, MD., Ph.D., Erik A. Nelson, Ph.D, Diana Cirstea, MD, Madhavi Bandi, Ph.D, Hiroshi Ikeda, MD, PhD, Gullu Gorgun, PhD, Sonia Vallet, MD., Samantha Pozzi, MD, Giulia Perrone, MD, Kishan Patel, Yiguo Hu, Ph.D, Matthew S Squires, Murray Yule, Elisabetta Calabrese, MD., Dharminder Chauhan, Ph.D, Nikhil C. Munshi, Kenneth C. Anderson, MD, Noopur Raje, MD.

Blood (2009) 114 (22): 3833.

https://doi.org/10.1182/blood.V114.22.3833.3833

Published: 2009

Journal Articles

CCL3 Impairs Osteoblast Function Via Downregulation of Osteocalcin.

Sonia Vallet, MD., Kishan Patel, Nileshwari Vaghela, Mariateresa Fulciniti, PhD, Petter Veiby, Teru Hideshima, M.D., Ph.D., Samantha Pozzi, MD, Loredana Santo, MD, Siddhartha Mukherjee, M.D., Diana Cirstea, MD, David T Scadden, MD, Kenneth C. Anderson, MD, Noopur Raje, MD.

Blood (2009) 114 (22): 739.

https://doi.org/10.1182/blood.V114.22.739.739

Published: 2009

Journal Articles

Overcoming p53 Loss with a Multi-Targeted Small Molecule Inhibitor in Multiple Myeloma.

Diana Cirstea, MD, Teru Hideshima, MD, PhD, Loredana Santo, MD, Sonia Vallet, MD, Samantha Pozzi, MD, Kishan Patel, Hiroshi Ikeda, MD, PhD, Hannes Loferer, PhD, Giulia Perrone, MD, Gullu Gorgun, PhD, Yiguo Hu, MD, PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2009) 114 (22): 4915.

https://doi.org/10.1182/blood.V114.22.4915.4915

Published: 2009

Journal Articles

Molecular Profiling of Extramedullary and Medullary Plasmacytomas.

Anuj Mahindra, MD, Samir B Amin, MBBS, Gabriela Motyckova, MD, PhD, Aliyah R. Sohani, MD, Kishan Patel, Sonia Vallet, MD., Gaurav Chetri, Adam Ackerman, Samantha Pozzi, MD, Loredana Santo, MD, Diana Cirstea, MD, Christiana E. Toomey, Ephraim P. Hochberg, MD, Paola Dal Cin, Teru Hideshima, MD, PhD, Kenneth C. Anderson, MD, Nikhil Munshi, Noopur Raje, MD

Blood (2009) 114 (22): 1806.

https://doi.org/10.1182/blood.V114.22.1806.1806

Published: 2009

Journal Articles

Restoration of Bone Balance Via Activin a Inhibition Results in Anti-Myeloma Activity

Blood (2008) 112 (11): 645.

https://doi.org/10.1182/blood.V112.11.645.645

Published: 2008

Journal Articles

Promoting Osteoblastogenesis Using a Novel Dkk-1 Neutralizing Antibody in the Treatment of Multiple Myeloma Related Bone Disease

Samantha Pozzi, MD, Hua Yan, MD, Sonia Vallet, M.D., Nileshwari Vaghela, MS, Mariateresa Fulciniti, PhD, Diana Cirstea, MD, Loredana Santo, M.D., Siddhartha Mukherjee, MD, Teru Hideshima, M.D., Ph.D., Linda Schirtzinger, M.S., Stuart Kuhstoss, Nikhil C. Munshi, MD, Kenneth C Anderson, MD, David Scadden, MD, Noopur Raje, MD

Blood (2008) 112 (11): 2739.

https://doi.org/10.1182/blood.V112.11.2739.2739

Published: 2008

Journal Articles

A Novel Aurora-a Kinase Inhibitor MLN8237 Induces Cytotoxicity and Cell Cycle Arrest in Experimental Multiple Myeloma Models.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Mala Mani, PhD, Teru Hideshima, M.D., Ph.D., Hiroshi Ikeda, MD, PhD, Giulia Perrone, MD, Loredana Santo, MD, Diana Cirstea, MD, Simona Blotta, Paul G. Richardson, MD, Jeffrey Ecsedy, Kenneth C. Anderson, MD

Blood (2008) 112 (11): 1719.

https://doi.org/10.1182/blood.V112.11.1719.1719

Published: 2008

Journal Articles

CCR1 Inhibition Targets Osteoclast-Myeloma Adhesion and Exerts in Vivo Anti-Osteoclast Activity

Soni a Vallet, MD, Nileshwari Vaghela, Mariateresa Fulciniti, PhD, Petter Veiby, Teru Hideshima, MD, PhD, Samantha Pozzi, MD, Loredana Santo, MD, Siddhartha Mukherjee, MD, Diana Cirstea, MD, David T. Scadden, MD, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2008) 112 (11): 2757.

https://doi.org/10.1182/blood.V112.11.2757.2757

Published: 2008

Journal Articles

AT7519, a Novel Small Molecule Multi-Cyclin Dependent Kinase Inhibitor, Induces Apoptosis in Multiple Myeloma VIA GSK3β

Loredana Santo, MD, Sonia Vallet, M.D., Teru Hideshima, M.D., Ph.D., Diana Cirstea, MD, Samantha Pozzi, MD, Nileshwari Vaghela, Hiroshi Ikeda, MD, PhD, Yutaka Okawa, MD, Gullu Gorgun, PhD, Giulia Perrone, MD, Elisabetta Calabrese, MD, Matthew S Squires, Marco Ladetto, MD, Nikhil C. Munshi, MD, Mario Boccadoro, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2008) 112 (11): 251.

https://doi.org/10.1182/blood.V112.11.251.251

Published: 2008

NARROW

With Equal Access, African Americans with Non-del17p Multiple Myeloma Have Superior Overall Survival, but del17p Still Carries Poor Prognosis across Race: A VA Study

Treatment Disparities in Minority Groups with Multiple Myeloma at a Large Safety-Net Hospital

Opioid Use Is NOT Associated with in-Hospital Mortality Among Patients with Sickle CELL Disease in the United States: Findings from the National Inpatient Sample

TAS-117, a Novel Selective Akt Inhibitor Demonstrates Significant Growth Inhibition in Multiple Myeloma Cells in Vitro and in Vivo

Selective HDAC6 Inhibition Via ACY-1215, Either Alone or in Combination with Bortezomib, Restores Osteoblast Function and Suppresses Osteoclast Differentiation in Multiple Myeloma

DEPTOR Is a Regulator of Response to mTOR Kinase Inhibitors in Multiple Myeloma

Immunomodulatory Effects of Histone Deacetylase 6 Inhibition in Suppressor Immune Cells in Multiple Myeloma

Lenalidomide In Combination with the Activin Receptor Type II Murine Fc Protein RAP-011: Preclinical Rationale for a Novel Anti-Myeloma Strategy

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor with Potent Activity Against Aurora Kinase and STAT3 In Combination with Lenalidomide Results In Synergistic Anti-Myeloma Activity

Molecular Sequaele of Activin A-Dependent Osteoblast Inhibition in Myeloma.

Bcl6 as a Novel Therapeutic Target in Multiple Myeloma (MM).

AT9283, a Small Molecule Multi-Targeted Kinase Inhibitor Induces Antimyeloma Activity Via Potent Aurora Kinase and STAT3 Inhibition.

CCL3 Impairs Osteoblast Function Via Downregulation of Osteocalcin.

Overcoming p53 Loss with a Multi-Targeted Small Molecule Inhibitor in Multiple Myeloma.

Molecular Profiling of Extramedullary and Medullary Plasmacytomas.

Restoration of Bone Balance Via Activin a Inhibition Results in Anti-Myeloma Activity

Promoting Osteoblastogenesis Using a Novel Dkk-1 Neutralizing Antibody in the Treatment of Multiple Myeloma Related Bone Disease

A Novel Aurora-a Kinase Inhibitor MLN8237 Induces Cytotoxicity and Cell Cycle Arrest in Experimental Multiple Myeloma Models.

CCR1 Inhibition Targets Osteoclast-Myeloma Adhesion and Exerts in Vivo Anti-Osteoclast Activity

AT7519, a Novel Small Molecule Multi-Cyclin Dependent Kinase Inhibitor, Induces Apoptosis in Multiple Myeloma VIA GSK3β

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American Society of Hematology

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