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Journal Articles

Genomic and Immunologic Analysis of Cmaf and Hypermutated Multiple Myeloma: Implications for Immunologic Therapy

Hearn Jay Cho, MD PhD, Deepak Perumal, PhD, Adeeb H Rahman, PhD, Donald Jackson, PhD, Michael Robbins, PhD, Seunghee Kim-Schultze, PhD, Sacha Gnjatic, PhD, Samir Parekh, MD, Jonathan J Keats, PhD, Daniel Auclair

Blood (2019) 134 (Supplement_1): 3093.

https://doi.org/10.1182/blood-2019-131274

Published: 2019

Journal Articles

High Dimensional Immune Profiling in Smoldering Multiple Myeloma Identifies Novel Organizing Features of the Tumor Microenvironment

Hearn Jay Cho, MD PhD, Deepak Perumal, PhD, Adeeb H Rahman, PhD, Seunghee Kim-Schultze, PhD, Jennifer Yesil, Daniel Auclair, Tineke Casneuf, PhD, Homer Adams, III, PhD, Samir Parekh, MD, Sacha Gnjatic, PhD, Nicolas Fernandez, PhD

Blood (2019) 134 (Supplement_1): 4384.

https://doi.org/10.1182/blood-2019-130554

Published: 2019

Journal Articles

E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients

Alessandro Lagana, PhD, Seongjee Park, Donna Edwards, Violetta Leshchenko, PhD, Marsha Crochiere, Yosef Landesman, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Deepak Perumal, PhD, Deepu Madduri, MD, Joshua Richter, Ajai Chari, MD, Hearn Jay Cho, MD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2018) 132 (Supplement 1): 3216.

https://doi.org/10.1182/blood-2018-99-116500

Published: 2018

Journal Articles

MAGE-A3 Promotes Chemotherapy Resistance and Proliferation in Multiple Myeloma through Regulation of BIM and p21 Cip1

Hearn Jay Cho, MD, Anna Huo-Chang Mei, MS, Kaity Tung, BS, Jessie Han, Deepak Perumal, PhD, Jonathan J Keats, PhD, Daniel Auclair, PhD, Ajai Chari, MD, Sundar Jagannath, MD, Samir Parekh, MD, Alessandro Lagana, PhD

Blood (2018) 132 (Supplement 1): 4464.

https://doi.org/10.1182/blood-2018-99-118692

Published: 2018

Journal Articles

Increased HLA-E Expression Correlates with Early Relapse in Multiple Myeloma

Blood (2018) 132 (Supplement 1): 59.

https://doi.org/10.1182/blood-2018-99-116828

Published: 2018

Journal Articles

Clonal Evolution in Newly Diagnosed Multiple Myeloma Patients: A Follow-up Study from the Mmrf Commpass Genomics Project

Alessandro Lagana, PhD, David Melnekoff, BS, MSc, Itai Beno, PhD, Violetta Leshchenko, PhD, Deepak Perumal, PhD, Jonathan J. Keats, PhD, Mary DeRome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2017) 130 (Supplement 1): 325.

https://doi.org/10.1182/blood.V130.Suppl_1.325.325

Published: 2017

Journal Articles

Single-Cell RNA Sequencing Reveals Distinct Transcriptomic Profiles of Multiple Myeloma with Implications for Personalized Medicine

David Melnekoff, BS, MSc, Alessandro Lagana, PhD, Wissam Hamou, PhD, Kimaada Allette, BS, Itai Beno, PhD, Violetta Leshchenko, PhD, Deepak Perumal, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Robert Sebra, PhD, Samir Parekh, MD

Blood (2017) 130 (Supplement 1): 62.

https://doi.org/10.1182/blood.V130.Suppl_1.62.62

Published: 2017

Journal Articles

Adar-Mediated Aberrant a-to-I RNA Editing Is Driven By 1q Amplification and Contributes to Proteasome Inhibitor Resistance in Multiple Myeloma

Alessandro Lagana, PhD, Violetta Leshchenko, PhD, David Melnekoff, BS, MSc, Itai Beno, PhD, Deepak Perumal, PhD, Jonathan Keats, PhD, Mary DeRome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2017) 130 (Supplement 1): 268.

https://doi.org/10.1182/blood.V130.Suppl_1.268.268

Published: 2017

Journal Articles

MAGE-a Inhibits Apoptosis in Multiple Myeloma through Regulation of Bim and PUMA

Hearn Jay Cho, MD PhD, Anna Huo-Chang Mei, MS, Jami Fukui, MD, Kaity Tung, BS, Deepak Perumal, PhD, Violetta Leshchenko, PhD, Alessandro Lagana, PhD, Seunghee Kim-Schultze, PhD, Ajai Chari, Sundar Jagannath, MD, Samir Parekh, MD

Blood (2017) 130 (Supplement 1): 4332.

https://doi.org/10.1182/blood.V130.Suppl_1.4332.4332

Published: 2017

Journal Articles

Aberrant a-to-I RNA Editing and Prognostic Impact of Adar in Multiple Myeloma Patients with 1q Amplification

Alessandro Lagana, PhD, Deepak Perumal, PhD, Violetta V Leshchenko, PhD, Pei-Yu Kuo, MS, Brian Kidd, PhD, Jonathan J Keats, PhD, Mary Derome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2016) 128 (22): 357.

https://doi.org/10.1182/blood.V128.22.357.357

Published: 2016

Journal Articles

MAGE-a Mediate Resistance to Chemotherapy in Multiple Myeloma through Regulation of Bcl-2 Proteins

Hearn Jay Cho, MD PhD, Anna Mei, MS, Jami Fukui, MD, Kaity Tung, BS, Violetta V Leshchenko, PhD, Alessandro Lagana, PhD, Manishkumar Patel, Seunghee Kim-Schulze, PhD, Deepak Perumal, PhD, Ajai Chari, MD, Sundar Jagannath, MD, Samir Parekh, MD

Blood (2016) 128 (22): 3277.

https://doi.org/10.1182/blood.V128.22.3277.3277

Published: 2016

Journal Articles

Integrative Network Analysis of Newly Diagnosed Multiple Myeloma Identifies a Novel RNA-Seq Based High Riskgene Signature

Alessandro Lagana, PhD, Deepak Perumal, PhD, David Melnekoff, BS, Ben Readhead, MBBS, Brian Kidd, PhD, Violetta V Leshchenko, PhD, Pei-Yu Kuo, MS, Jonathan J Keats, PhD, Mary Derome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2016) 128 (22): 3285.

https://doi.org/10.1182/blood.V128.22.3285.3285

Published: 2016

Journal Articles

Network Modeling Reveals CDC42BPA and CLEC11A As Novel Driver Genes of t(4; 14) Multiple Myeloma

Deepak Perumal, PhD, Alessandro Lagana', PhD, David Melnekoff, BS, Ben Readhead, MBBS, Brian Kidd, PhD, Violetta V Leshchenko, PhD, Pei-Yu Kuo, MS, Jennifer Yesil, MS, Mary Derome, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2016) 128 (22): 802.

https://doi.org/10.1182/blood.V128.22.802.802

Published: 2016

Journal Articles

SOX11 Cooperates with CCND1 in Mantle Cell Lymphoma Pathogenesis

Pei-Yu Kuo, MS, Zewei Jiang, MD, Deepak Perumal, PhD, Violetta V Leshchenko, PhD, Alessandro Lagana', PhD, Samuel G. Katz, MD PhD, Loren D. Walensky, MD PhD, Rita Shaknovich, MD, PhD, B. Hilda Ye, PhD, Samir Parekh, MD

Blood (2015) 126 (23): 1253.

https://doi.org/10.1182/blood.V126.23.1253.1253

Published: 2015

Journal Articles

Towards a Network-Based Molecular Taxonomy of Newly Diagnosed Multiple Myeloma

Alessandro Lagana, PhD, Ben Readhead, Deepak Perumal, PhD, Brian Kidd, Hearn Jay Cho, MD PhD, Ajai Chari, MD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2015) 126 (23): 840.

https://doi.org/10.1182/blood.V126.23.840.840

Published: 2015

Journal Articles

Patient-Specific Mutation-Derived Tumor Antigens As Targets for Cancer Immunotherapy in Multiple Myeloma

Deepak Perumal, PhD, Alessandro Lagana', PhD, Alex Rubinsteyn, PhD, John P Finnigan, Jr., BS, Pei-Yu Kuo, MS, Violetta V Leshchenko, PhD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Jeff Hammerbacher, BA, Eric Schadt, PhD, Nina Bhardwaj, MD PhD, Samir Parekh, MD

Blood (2015) 126 (23): 1851.

https://doi.org/10.1182/blood.V126.23.1851.1851

Published: 2015

Journal Articles

Weighted Gene Co-Expression Network Analysis (WGCNA) Identifies Highly Proliferative Myeloma Subgroup Responsive to CDK4/ARK5 Inhibition

Deepak Perumal, PhD, Violetta V. Leshchenko, PhD, Pei-Yu Kuo, MS, Zewei Jiang, MD, Ben Readhead, MBBS, Caroline Eden, BS, Sai Krishna Athaluri Divakar, PhD, Weijia Zhang, PhD, Hearn Jay Cho, MD PhD, Ajai Chari, MD, M.V.Ramana Reddy, PhD, E. Premkumar Reddy, PhD, Joel Dudley, PhD, Sundar Jagannath, MD, Samir Parekh, MD

Blood (2014) 124 (21): 3445.

https://doi.org/10.1182/blood.V124.21.3445.3445

Published: 2014

Journal Articles

An Integrative Network Approach for Genomic Discovery and Personalized Therapy in Relapsed Multiple Myeloma

Ben Readhead, MBBS, Krishan Kania, Caroline Eden, Deepak Perumal, PhD, Vickram Gidwani, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Sundar Jagannath, MD, Pei-Yu Kuo, MS, Brian Kidd, PhD, Joel Dudley, PhD, Samir Parekh

Blood (2014) 124 (21): 3426.

https://doi.org/10.1182/blood.V124.21.3426.3426

Published: 2014

Journal Articles

High-Resolution Genomic Methylation Analysis Using Next Generation Sequencing Identifies Loci Associated With Differential Prognosis In Mantle Cell Lymphoma Patients Treated With Bortezomib + DA-EPOCH-R

Violetta V. Leshchenko, PhD, Pei-Yu Kuo, MS, Deepak Perumal, PhD, Melissa J Fazzari, PhD, Francine E. Garrett-Bakelman, MD, PhD, Nakhle S Saba, MD, Delong Liu, PhD, Weijia Zhang, PhD, Joshua Brody, MD, Ari M. Melnick, MD, Kieron Dunleavy, MD, Wyndham H Wilson, MD, PhD, Adrian Wiestner, MD, PhD, Samir Parekh, MD

Blood (2013) 122 (21): 3760.

https://doi.org/10.1182/blood.V122.21.3760.3760

Published: 2013

NARROW

Genomic and Immunologic Analysis of Cmaf and Hypermutated Multiple Myeloma: Implications for Immunologic Therapy

High Dimensional Immune Profiling in Smoldering Multiple Myeloma Identifies Novel Organizing Features of the Tumor Microenvironment

E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients

MAGE-A3 Promotes Chemotherapy Resistance and Proliferation in Multiple Myeloma through Regulation of BIM and p21 Cip1

Increased HLA-E Expression Correlates with Early Relapse in Multiple Myeloma

Clonal Evolution in Newly Diagnosed Multiple Myeloma Patients: A Follow-up Study from the Mmrf Commpass Genomics Project

Single-Cell RNA Sequencing Reveals Distinct Transcriptomic Profiles of Multiple Myeloma with Implications for Personalized Medicine

Adar-Mediated Aberrant a-to-I RNA Editing Is Driven By 1q Amplification and Contributes to Proteasome Inhibitor Resistance in Multiple Myeloma

MAGE-a Inhibits Apoptosis in Multiple Myeloma through Regulation of Bim and PUMA

Aberrant a-to-I RNA Editing and Prognostic Impact of Adar in Multiple Myeloma Patients with 1q Amplification

MAGE-a Mediate Resistance to Chemotherapy in Multiple Myeloma through Regulation of Bcl-2 Proteins

Integrative Network Analysis of Newly Diagnosed Multiple Myeloma Identifies a Novel RNA-Seq Based High Riskgene Signature

Network Modeling Reveals CDC42BPA and CLEC11A As Novel Driver Genes of t(4; 14) Multiple Myeloma

SOX11 Cooperates with CCND1 in Mantle Cell Lymphoma Pathogenesis

Towards a Network-Based Molecular Taxonomy of Newly Diagnosed Multiple Myeloma

Patient-Specific Mutation-Derived Tumor Antigens As Targets for Cancer Immunotherapy in Multiple Myeloma

Weighted Gene Co-Expression Network Analysis (WGCNA) Identifies Highly Proliferative Myeloma Subgroup Responsive to CDK4/ARK5 Inhibition

An Integrative Network Approach for Genomic Discovery and Personalized Therapy in Relapsed Multiple Myeloma

High-Resolution Genomic Methylation Analysis Using Next Generation Sequencing Identifies Loci Associated With Differential Prognosis In Mantle Cell Lymphoma Patients Treated With Bortezomib + DA-EPOCH-R

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American Society of Hematology

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ASH Publications

American Society of Hematology

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