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Journal Articles

Assay Dependent Reversal of the Oral and Parenteral Anti-Xa Agents By Andexanet Alfa

Fakiha Siddiqui, Debra Hoppensteadt, PhD, Jeanine Walenga, PhD, Walter Jeske, PhD, Alfonso J Tafur, MD MS, Eduardo Ramacciotti, PhD MD, Jawed Fareed, PhD

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-142653

Published: 2020

Journal Articles

Validation of the Bioequivalence of USP Potency Adjusted Porcine, Ovine, and Bovine Heparins

Nausheen Baig, Ahmed Kouta, Walter Jeske, PhD, Debra Hoppensteadt, PhD, Jeanine Walenga, PhD, Omer Iqbal, MD, Fakiha Siddiqui, Mamdouh Bakhos, MD, Jawed Fareed, PhD

Blood (2020) 136 (Supplement 1): 6.

https://doi.org/10.1182/blood-2020-142861

Published: 2020

Journal Articles

USP Potency Adjusted Bovine Mucosal Heparins (BMH) Are Comparable to Porcine Mucosal Heparin (PMH) at Equivalent Levels

Ahmed Kouta, Walter Jeske, PhD, Rick Duff, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 165.

https://doi.org/10.1182/blood-2019-131943

Published: 2019

Journal Articles

Decreased Thrombin Generation Potential in Lymphoma Patients Is Associated with Increased D-Dimer, CRP, Vwf and TNF-α. Interrelationship between Thrombogenesis and Inflammation

Fakiha Siddiqui, Emily Bontekoe, Darko Antic, PhD, Debra Hoppensteadt, PhD, Grigoris Gerotziafas, MD PhD, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 5239.

https://doi.org/10.1182/blood-2019-128440

Published: 2019

Journal Articles

Biomarkers of Hemostatic Dysregulation and Inflammation in Lymphoma: Potential Relevance to Thrombogenesis

Darko Antic, PhD, Natasa Milic, Emily Bontekoe, Debra Hoppensteadt, PhD, Vladislava Djurasinovic, Vojin Vukovic, Vladimir Otasevic, Kristina Tomic, Biljana Mihaljevic, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 4945.

https://doi.org/10.1182/blood-2019-129957

Published: 2019

Journal Articles

Prothrombinase Induced Clotting Time Is More Sensitive then aPTT and PT and Can be Used for the Monitoring of Anti-Xa Agents in Whole Blood and Plasma

Debra Hoppensteadt, PhD, Emily Bontekoe, Fakiha Siddiqui, Ambar Farooqui, Omer Iqbal, MD, Walter Jeske, PhD, Jeanine Walenga, PhD, Alfonso J Tafur, MD MS, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 3374.

https://doi.org/10.1182/blood-2019-131221

Published: 2019

Journal Articles

Dysregulation of Hemostatic Biomarkers, Inflammatory Biomarkers, and Alteration of Cellular Indices As Predictors of Adverse Outcomes in Pulmonary Embolism Patients

Iman Darwish, Yevgeniy Brailovsky, DO, Amir Darki, MD MSc, Debra Hoppensteadt, PhD, Brett Slajus, Emily Bontekoe, Frank De Stefano, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 2408.

https://doi.org/10.1182/blood-2019-126876

Published: 2019

Journal Articles

Bovine Heparin Demonstrates the Same Interaction with HIT Antibodies As Porcine Heparin

Jeanine Walenga, PhD, Walter Jeske, PhD, Sabrina Bertini, Giulia Risi, Michelle Sung, BS, Ambar Farooqui, Cassie Bacher, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Bruce Lewis, Mamdouh Bakhos, MD

Blood (2019) 134 (Supplement_1): 2351.

https://doi.org/10.1182/blood-2019-127304

Published: 2019

Journal Articles

Comparative Studies on the Interaction of Unfractionated Heparin and Sulodexide with Functional Anti-Heparin Platelet Factor 4 Antibodies

Ambar Farooqui, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Cassie Bacher, Jeanine Walenga, PhD, Ahmed Kouta, Walter Jeske, PhD, Bruce Lewis, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 2446.

https://doi.org/10.1182/blood-2019-131825

Published: 2019

Journal Articles

Biomarkers of Hemostatic Activation and Inflammation Are Associated with Altered Coagulation Parameters in Sepsis Patients

Emily Bontekoe, Matthew T. Rondina, MD, Debra Hoppensteadt, PhD, Elizabeth Middleton, MD, Antoinette Blair, Fakiha Siddiqui, Divya Joshi, Alyssandra Abrenica, Iman Darwish, Maryanne Amour, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 2401.

https://doi.org/10.1182/blood-2019-130420

Published: 2019

Journal Articles

Potency Equated Porcine and Bovine Mucosal Heparin Are Bioequivalent in Terms of Biochemical and Pharmacological Effects

Nausheen Baig, Ahmed Kouta, Fakiha Siddiqui, Ambar Farooqui, Debra Hoppensteadt, PhD, Walter Jeske, PhD, Omer Iqbal, MD, Cassie Bacher, Sharan Krishnappan, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 3665.

https://doi.org/10.1182/blood-2019-126075

Published: 2019

Journal Articles

Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban By Andexanet Alfa As Measured By Whole Blood Thromboelastographic Analysis

Siddharth Mehrotra, Debra Hoppensteadt, PhD, Walter Jeske, PhD, Omer Iqbal, MD, Alfonso J Tafur, MD MS, Bruce Lewis, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 1155.

https://doi.org/10.1182/blood-2019-131907

Published: 2019

Journal Articles

Andexanet Alpha Differentially Neutralizes the Anticoagulant, Antiprotease and Thrombin Generation Inhibitory Effects of Unfractionated Heparin, Enoxaparin and Fondaparinux

Fakiha Siddiqui, Alfonso J Tafur, MD MS, Debra Hoppensteadt, PhD, Jeanine Walenga, PhD, Walter Jeske, PhD, Emily Bontekoe, Ahmed Kouta, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 1158.

https://doi.org/10.1182/blood-2019-127072

Published: 2019

Journal Articles

Development of an Algorithm to Predict Mortality in Patients with Sepsis and Coagulopathy

Amanda Walborn, PhD, Debra Hoppensteadt, PhD, Matthew T. Rondina, MD, Jawed Fareed, PhD

Blood (2018) 132 (Supplement 1): 3791.

https://doi.org/10.1182/blood-2018-99-116701

Published: 2018

Journal Articles

Symptom Duration Is Positively Correlated with Factor XIIIa Activity in Acute Pulmonary Embolism

Yevgeniy Brailovsky, DO, Debra Hoppensteadt, PhD, Omer Iqbal, MD, Kevin Simpson, Nathan Mcclane, Jawed Fareed, PhD, Amir Darki, MD MSc

Blood (2018) 132 (Supplement 1): 5047.

https://doi.org/10.1182/blood-2018-99-119733

Published: 2018

Journal Articles

Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum

Fakiha Siddiqui, Siddharth Mehrotra, Vishnu Venkitasubramony, Rithik Raina, Lorenzo Storino Ramacciotti, Jack Bontekoe, BS, Omer Iqbal, MD, Debra Hoppensteadt, PhD, Walter Jeske, PhD, Jawed Fareed, PhD

Blood (2018) 132 (Supplement 1): 2520.

https://doi.org/10.1182/blood-2018-99-116993

Published: 2018

Journal Articles

Relationship of Markers of Inflammation, Infection and Endothelial Function to Mortality and Severity of Coagulopathy in Patients with Sepsis-Associated DIC

Debra Hoppensteadt, PhD, Amanda Walborn, PhD, Matthew T. Rondina, MD, Jawed Fareed, PhD

Blood (2018) 132 (Supplement 1): 2495.

https://doi.org/10.1182/blood-2018-99-115302

Published: 2018

Journal Articles

Decreased Thrombin Generation Potential Is Associated with Increased Thrombin Generation Markers in Sepsis Associated Coagulopathy

Fakiha Siddiqui, Rajan Laddu, Debra Hoppensteadt, PhD, Matthew T. Rondina, MD, Yevgeniy Brailovsky, DO, Jawed Fareed, PhD

Blood (2018) 132 (Supplement 1): 2505.

https://doi.org/10.1182/blood-2018-99-119675

Published: 2018

Journal Articles

Biomarkers of Endothelial Function in Sepsis-Associated Disseminated Intravascular Coagulation

Amanda Walborn, Grace Wegryzn, Susan Walborn, Paula D'Almeida Maia, BA, BS, Michael Mosier, Debra Hoppensteadt, PhD, Matthew T. Rondina, MD, Jawed Fareed, PhD

Blood (2017) 130 (Supplement 1): 1084.

https://doi.org/10.1182/blood.V130.Suppl_1.1084.1084

Published: 2017

Journal Articles

Biomarkers of Platelet Activation and Their Prognostic Value in Patients in Sepsis Associated Coagulopathy

Grace Wegryzn, Debra Hoppensteadt, PhD, Amanda Walborn, Paula D'Almeida Maia, BA, BS, Susan Walborn, Richard Green, Michael Mosier, Matthew T. Rondina, MD, Jawed Fareed, PhD

Blood (2017) 130 (Supplement 1): 3632.

https://doi.org/10.1182/blood.V130.Suppl_1.3632.3632

Published: 2017

NARROW

Assay Dependent Reversal of the Oral and Parenteral Anti-Xa Agents By Andexanet Alfa

Validation of the Bioequivalence of USP Potency Adjusted Porcine, Ovine, and Bovine Heparins

USP Potency Adjusted Bovine Mucosal Heparins (BMH) Are Comparable to Porcine Mucosal Heparin (PMH) at Equivalent Levels

Decreased Thrombin Generation Potential in Lymphoma Patients Is Associated with Increased D-Dimer, CRP, Vwf and TNF-α. Interrelationship between Thrombogenesis and Inflammation

Biomarkers of Hemostatic Dysregulation and Inflammation in Lymphoma: Potential Relevance to Thrombogenesis

Prothrombinase Induced Clotting Time Is More Sensitive then aPTT and PT and Can be Used for the Monitoring of Anti-Xa Agents in Whole Blood and Plasma

Dysregulation of Hemostatic Biomarkers, Inflammatory Biomarkers, and Alteration of Cellular Indices As Predictors of Adverse Outcomes in Pulmonary Embolism Patients

Bovine Heparin Demonstrates the Same Interaction with HIT Antibodies As Porcine Heparin

Comparative Studies on the Interaction of Unfractionated Heparin and Sulodexide with Functional Anti-Heparin Platelet Factor 4 Antibodies

Biomarkers of Hemostatic Activation and Inflammation Are Associated with Altered Coagulation Parameters in Sepsis Patients

Potency Equated Porcine and Bovine Mucosal Heparin Are Bioequivalent in Terms of Biochemical and Pharmacological Effects

Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban By Andexanet Alfa As Measured By Whole Blood Thromboelastographic Analysis

Andexanet Alpha Differentially Neutralizes the Anticoagulant, Antiprotease and Thrombin Generation Inhibitory Effects of Unfractionated Heparin, Enoxaparin and Fondaparinux

Development of an Algorithm to Predict Mortality in Patients with Sepsis and Coagulopathy

Symptom Duration Is Positively Correlated with Factor XIIIa Activity in Acute Pulmonary Embolism

Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum

Relationship of Markers of Inflammation, Infection and Endothelial Function to Mortality and Severity of Coagulopathy in Patients with Sepsis-Associated DIC

Decreased Thrombin Generation Potential Is Associated with Increased Thrombin Generation Markers in Sepsis Associated Coagulopathy

Biomarkers of Endothelial Function in Sepsis-Associated Disseminated Intravascular Coagulation

Biomarkers of Platelet Activation and Their Prognostic Value in Patients in Sepsis Associated Coagulopathy

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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