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Journal Articles

Manipulation of Tropomysin 1 in iPSCs to Enhance in Vitro Blood Cell Production

Christopher Thom, MD PhD, Chintan Jobaliya, Benjamin F Voight, PhD, Stella P Chou, MD, Deborah L French, PhD

Blood (2020) 136 (Supplement 1): 34–35.

https://doi.org/10.1182/blood-2020-142317

Published: 2020

Journal Articles

Utilizing CRISPR-CAS9 Gene Editing Technology in Human Pluripotent Stem Cells to Study Platelet Integrin αIIbβ3 Function

Karen Fong, MD PhD, Chintan Jobaliya, Jean Ann Maguire, PhD, Mortimer Poncz, MD, Deborah L French, PhD, Joel S. Bennett, MD

Blood (2020) 136 (Supplement 1): 3.

https://doi.org/10.1182/blood-2020-134268

Published: 2020

Journal Articles

Tropomyosin 1 Genetically Constrains in Vitro Megakaryopoiesis

Christopher Thom, MD PhD, Chintan Jobaliya, Kimberly Lorenz, PhD, Jean Ann Maguire, PhD, Alyssa Gagne, Paul Gadue, PhD, Deborah L French, PhD, Benjamin F Voight, PhD

Blood (2019) 134 (Supplement_1): 3612.

https://doi.org/10.1182/blood-2019-121538

Published: 2019

Journal Articles

A Novel Approach for Generating Platelet-Delivered FVIII: Role of Transient LRP1 Expression during Megakaryopoiesis

John Tkaczynski, BS, Randolph Lyde, PhD, Hyunsook Ahn, MSc, Francis Ayombil, PhD, Sara Borst, BS, Paul Gadue, PhD, Deborah L French, PhD, Denise Sabatino, PhD, Rodney M. Camire, PhD, Mortimer Poncz, MD

Blood (2019) 134 (Supplement_1): 1102.

https://doi.org/10.1182/blood-2019-124788

Published: 2019

Journal Articles

The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction

Brian Estevez, PhD, Sara Borst, BS, Danuta Jadwiga Jarocha, PhD, Varun Sudunagunta, Michael Gonzalez, PhD, Peng Gao, Kai Tan, Deborah L French, PhD, Paul Gadue, PhD, Mortimer Poncz, MD

Blood (2019) 134 (Supplement_1): 220.

https://doi.org/10.1182/blood-2019-124851

Published: 2019

Journal Articles

Customized Induced Pluripotent Stem Cell-Derived Red Cell Reagents

David Posocco, Hyun H An, Jean Ann Maguire, Judith Aeschlimann, Deborah L French, PhD, Paul Gadue, PhD, Connie M. Westhoff, PhD, Stella T Chou, MD

Blood (2017) 130 (Supplement 1): 3.

https://doi.org/10.1182/blood.V130.Suppl_1.3.3

Published: 2017

Journal Articles

Mutation-Specific Signaling Profiles and Therapeutic Vulnerabilities of Induced Pluripotent Stem Cell Models of Juvenile Myelomonocytic Leukemia

Sarah K Tasian, MD, Jessica A Casas, MD MPH, David Posocco, Shilpa Gandre-Babbe, Alyssa Gagne, Ge Liang, Mignon L. Loh, MD, Mitchell J Weiss, MD PhD, Deborah L French, PhD, Stella T Chou, MD

Blood (2017) 130 (Supplement 1): 1678.

https://doi.org/10.1182/blood.V130.Suppl_1.1678.1678

Published: 2017

Journal Articles

Dysregulation of the TGF β Pathway in Induced Pluripotent Stem Cells (iPSCs) Generated from Patients with Diamond Blackfan Anemia (DBA)

Jingping Ge, Marisa Apicella, Jason A. Mills, Loic Garcon, Deborah L. French, PhD, Mitchell J. Weiss, MD PhD, Monica Bessler, MDPhD, Philip J Mason, PhD

Blood (2014) 124 (21): 254.

https://doi.org/10.1182/blood.V124.21.254.254

Published: 2014

Journal Articles

Inducible Gata1 Suppression As a Novel Strategy to Expand Physiologic Megakaryocyte Production from Embryonic Stem Cells

Ji-Yoon Noh, PhD, Shilpa Gandre-Babbe, PhD, Yuhuan Wang, PhD, Vincent Hayes, BS, Yu Yao, Paul Gadue, PhD, Spencer Sullivan, MD, Stella T. Chou, MD, Vikram R Paralkar, MD, Kellie R Machlus, PhD, Joseph E. Italiano, PhD, Michael Kyba, PhD, Deborah L. French, PhD, Mortimer Poncz, MD, Mitchell J. Weiss, MD PhD

Blood (2014) 124 (21): 3846.

https://doi.org/10.1182/blood.V124.21.3846.3846

Published: 2014

Journal Articles

Aryl Hydrocarbon Receptor (AhR) Antagonist Stemregenin 1 (SR1) Enhances in Vitro- and in Vivo-Derived Platelets (PLTs) From Human Megakaryocytes (MKs)

Yuhuan Wang, PhD, Vincent M. Hayes, Lin Lu, Ph.D, Xiaoji Chen, Rudy Fuentes, PhD, Qiang Jeremy Wen, MD, PhD, Stella T Chou, MD, John Crispino, PhD, Patrick Paddison, PhD, Deborah L. French, PhD, Beverly Torok-Storb, PhD, Mortimer Poncz, MD

Blood (2012) 120 (21): 3450.

https://doi.org/10.1182/blood.V120.21.3450.3450

Published: 2012

Journal Articles

Tissue-Specific Transgene Expression in Induced Pluripotent Stem (iPS) Cell-Derived Megakaryocytes: Correction of Glanzmann Thrombasthenia (GT)

Spencer K. Sullivan, MD, Jason A. Mills, PhD, Li Zhai, MD, Prasuna Paluru, MS, Karen Vo, Michele Lambert, MD, Sevasti B. Koukouritaki, PhD, Juan Fang, MD, David A. Wilcox, PhD, Deborah L. French, PhD, Mortimer Poncz, MD, Paul Gadue, PhD

Blood (2012) 120 (21): 387.

https://doi.org/10.1182/blood.V120.21.387.387

Published: 2012

Journal Articles

The Aryl Hydrocarbon Receptor (AhR) Regulates the Production of Bipotential Hematopoietic Progenitor Cells

Brenden W Smith, Sarah S Rozelle, Paul Gadue, PhD, Deborah L. French, PhD, David H.K. Chui, MD, Martin H. Steinberg, MD, David H. Sherr, Ph.D, George J. Murphy, Ph.D

Blood (2012) 120 (21): 766.

https://doi.org/10.1182/blood.V120.21.766.766

Published: 2012

Journal Articles

Patient-Derived Induced Pluripotent Stem Cells Recapitulate Hematopoietic Abnormalities of Juvenile Myelomonocytic Leukemia

Gandre-Babbe Shilpa, PhD, Stella T Chou, MD, Deborah L. French, PhD, Michelle Kang, Julie Weng, Helene Favre, Mignon L Loh, MD, Mitchell J Weiss, MD

Blood (2011) 118 (21): 637.

https://doi.org/10.1182/blood.V118.21.637.637

Published: 2011

Journal Articles

Common Recurrent DKC1 Mutation A353V Does Not Support Telomere Maintenance in Induced Pluripotent Stem Cells

Baiwei Gu, Ph.D, Jason A. Mills, PhD, Jian-meng Fan, B.S, Deborah L. French, PhD, Monica Bessler, MD, PhD, Philip Mason, PhD

Blood (2011) 118 (21): 50.

https://doi.org/10.1182/blood.V118.21.50.50

Published: 2011

Journal Articles

Targeted Gene Correction of Glanzmann Thrombasthenia Induced Pluripotent Stem Cells Restores Surface Expression and Fibrinogen Binding of Integrin αIIbβ3,

Spencer Sullivan, MD, Jason A. Mills, PhD, Li Zhai, MD, Prasuna Paluru, MS, Guohua Zhao, PhD, Lin Lu, PhD, Michele Lambert, MD, Deborah L. French, PhD, Mortimer Poncz, MD, Paul Gadue, PhD

Blood (2011) 118 (21): 4173.

https://doi.org/10.1182/blood.V118.21.4173.4173

Published: 2011

Journal Articles

Patient-Derived Induced Pluripotent Stem Cells Reveal Distinct Hematopoietic Defects Conferred by Trisomy 21 and Truncated GATA-1

Stella T Chou, MD, Daniel VanDorn, Yu Yao, Deborah L. French, PhD, Mitchell J Weiss, MD

Blood (2011) 118 (21): 911.

https://doi.org/10.1182/blood.V118.21.911.911

Published: 2011

Journal Articles

Generation of Megakaryocytes from Human Embryonic Stem Cells.

Deborah L. French, PhD, Marketa Jirouskova, PhD, Marion Kennedy, MS, Barry S. Coller, MD, Gordon Keller, PhD

Blood (2007) 110 (11): 1265.

https://doi.org/10.1182/blood.V110.11.1265.1265

Published: 2007

NARROW

Manipulation of Tropomysin 1 in iPSCs to Enhance in Vitro Blood Cell Production

Utilizing CRISPR-CAS9 Gene Editing Technology in Human Pluripotent Stem Cells to Study Platelet Integrin αIIbβ3 Function

Tropomyosin 1 Genetically Constrains in Vitro Megakaryopoiesis

A Novel Approach for Generating Platelet-Delivered FVIII: Role of Transient LRP1 Expression during Megakaryopoiesis

The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction

Customized Induced Pluripotent Stem Cell-Derived Red Cell Reagents

Mutation-Specific Signaling Profiles and Therapeutic Vulnerabilities of Induced Pluripotent Stem Cell Models of Juvenile Myelomonocytic Leukemia

Dysregulation of the TGF β Pathway in Induced Pluripotent Stem Cells (iPSCs) Generated from Patients with Diamond Blackfan Anemia (DBA)

Inducible Gata1 Suppression As a Novel Strategy to Expand Physiologic Megakaryocyte Production from Embryonic Stem Cells

Aryl Hydrocarbon Receptor (AhR) Antagonist Stemregenin 1 (SR1) Enhances in Vitro- and in Vivo-Derived Platelets (PLTs) From Human Megakaryocytes (MKs)

Tissue-Specific Transgene Expression in Induced Pluripotent Stem (iPS) Cell-Derived Megakaryocytes: Correction of Glanzmann Thrombasthenia (GT)

The Aryl Hydrocarbon Receptor (AhR) Regulates the Production of Bipotential Hematopoietic Progenitor Cells

Patient-Derived Induced Pluripotent Stem Cells Recapitulate Hematopoietic Abnormalities of Juvenile Myelomonocytic Leukemia

Common Recurrent DKC1 Mutation A353V Does Not Support Telomere Maintenance in Induced Pluripotent Stem Cells

Targeted Gene Correction of Glanzmann Thrombasthenia Induced Pluripotent Stem Cells Restores Surface Expression and Fibrinogen Binding of Integrin αIIbβ3,

Patient-Derived Induced Pluripotent Stem Cells Reveal Distinct Hematopoietic Defects Conferred by Trisomy 21 and Truncated GATA-1

Generation of Megakaryocytes from Human Embryonic Stem Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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