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Journal Articles

Discovery and Development of MEDI7247, a Novel Pyrrolobenzodiazepine (PBD)-Based Antibody Drug Conjugate Targeting ASCT2, for Treating Hematological Cancers

Nabendu Pore, Kevin P Schifferli, Noel R Monks, Ravinder Tammali, Martin Borrok, Elaine Hurt, Matt Flynn, Marlon Rebelatto, Danielle M. Townsley, MD MSc, Mary Jane Hinrichs, Rakesh Dixit, Steven Coats, Ronald Herbst, David Tice

Blood (2018) 132 (Supplement 1): 4071.

https://doi.org/10.1182/blood-2018-99-119836

Published: 2018

Journal Articles

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Fernanda Gutierrez-Rodrigues, PhD, Carrie Diamond, MD, Ruba Shalhoub, André Pinto, Flávia S Donaires, PhD, Diego V Clé, MD PhD, Luiz Guilherme Darrigo, PhD, Luiz Fernando Catto, MD, Xing Fan, MD, Maria del Pilar Fernandez Ibanez, Sachiko Kajigaya, PhD, Cynthia E. Dunbar, MD, Carmem M. S. Bonfim, MD, Danielle M. Townsley, MD MSc, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2587.

https://doi.org/10.1182/blood-2018-99-115026

Published: 2018

Journal Articles

Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies

Fernanda Gutierrez-Rodrigues, PhD, Flávia S Donaires, PhD, André Pinto, Alana Vicente, MD, Laura Dillon, PhD, Diego V Clé, MDPhD, Bárbara Santana, Maria del Pilar Fernandez Ibanez, Danielle M. Townsley, MD MSc, Sachiko Kajigaya, PhD, Christopher S. Hourigan, DPhil FACP FRCP, James N. Cooper, MD, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 539.

https://doi.org/10.1182/blood-2018-99-115430

Published: 2018

Journal Articles

Single Cell Transcriptome Analysis of GATA2 Deficiency in Hematopoiesis Modeled with Induced Pluripotent Stem Cells

Francis Guitart, BA, Moonjung Jung, MD, Stefan Cordes, MD PhD, Shiqin Yu, Jizhong Zou, So Gun Hong, PhD, Vinh Dang, Diego A Espinoza, BA, Amy Hsu, Steven M. Holland, MD, Danielle M. Townsley, MD MSc, Cynthia E. Dunbar, MD, Thomas Winkler, MD

Blood (2018) 132 (Supplement 1): 5087.

https://doi.org/10.1182/blood-2018-99-118410

Published: 2018

Journal Articles

Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Xing Fan, MD, Thomas Winkler, MD, Ronan Desmond, MD, Bogdan Dumitriu, MD, Danielle M. Townsley, MD MSc, Maria del Pilar Fernandez Ibanez, Fernanda Gutierrez-Rodrigues, PhD, Sophia Grasmeder, RN, Ma Evette Barranta, Diane Madey, Jennifer Lotter, Janet Valdez, Katherine R. Calvo, MD PhD, Colin Wu, PhD, Neal S. Young, MD, Cynthia E. Dunbar, MD

Blood (2018) 132 (Supplement 1): 538.

https://doi.org/10.1182/blood-2018-99-112994

Published: 2018

Journal Articles

High Resolution Mass Cytometry (CyTOF) in Aplastic Anaemia (AA) Can Identify an Aberrant Treg Subset with Pro-Inflammatory Properties, Predicting Poor Response to Immunosuppressive Therapy

Shahram Kordasti, MD PhD, Thomas Seidl, Richard J Ellis, PhD, Austin Kulasekararaj, Xingmin Feng, PhD, Danielle M. Townsley, MD MSc, Susanne Heck, PhD, Neal S. Young, MD, Judith C Marsh, MD, Ghulam J. Mufti, DM, FRCP, FRCPath

Blood (2014) 124 (21): 1600.

https://doi.org/10.1182/blood.V124.21.1600.1600

Published: 2014

Journal Articles

Regulatory Mutations in GATA2 Associated with Aplastic Anemia

Danielle M. Townsley, MD, MSc, Amy Hsu, B.S., Bogdan Dumitriu, MD, Steven M. Holland, MD, Neal S. Young, MD

Blood (2012) 120 (21): 3488.

https://doi.org/10.1182/blood.V120.21.3488.3488

Published: 2012

Journal Articles

Very Short Telomeres of Peripheral Blood Leukocytes Precede Clinical Progression to Myelodysplasia with Monosomy 7 in Aplastic Anemia Patients

Bogdan Dumitriu, MD, Yasutaka Ueda, MD, PhD, Sachiko Kajigaya, PhD, Danielle M. Townsley, MD, MSc, Neal S. Young, MD

Blood (2012) 120 (21): 1265.

https://doi.org/10.1182/blood.V120.21.1265.1265

Published: 2012

Journal Articles

Even “Moderate” Dose Cyclophosphamide for Severe Aplastic Anemia Is Associated with Significant Toxicities and Does Not Prevent Relapse and Clonal Evolution

Phillip Scheinberg, MD, Danielle M. Townsley, MD, MSc, Bogdan Dumitriu, MD, Olga Rios, RN, Barbara Weinstein, RN, Minoo Battiwalla, MD, MS, Richard Childs, MD, Cynthia E. Dunbar, MD, A. John Barrett, MD, Colin O. Wu, Neal S. Young, MD

Blood (2012) 120 (21): 1259.

https://doi.org/10.1182/blood.V120.21.1259.1259

Published: 2012

Journal Articles

Clinical and Genetic Heterogeneity of Telomere Diseases.

Danielle M. Townsley, MD, MSc, Bogdan Dumitriu, MD, Sachiko Kajigaya, PhD, Rodrigo T. Calado, Phillip Scheinberg, MD, Neal S. Young, MD

Blood (2012) 120 (21): 2373.

https://doi.org/10.1182/blood.V120.21.2373.2373

Published: 2012

NARROW

Discovery and Development of MEDI7247, a Novel Pyrrolobenzodiazepine (PBD)-Based Antibody Drug Conjugate Targeting ASCT2, for Treating Hematological Cancers

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies

Single Cell Transcriptome Analysis of GATA2 Deficiency in Hematopoiesis Modeled with Induced Pluripotent Stem Cells

Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

High Resolution Mass Cytometry (CyTOF) in Aplastic Anaemia (AA) Can Identify an Aberrant Treg Subset with Pro-Inflammatory Properties, Predicting Poor Response to Immunosuppressive Therapy

Regulatory Mutations in GATA2 Associated with Aplastic Anemia

Very Short Telomeres of Peripheral Blood Leukocytes Precede Clinical Progression to Myelodysplasia with Monosomy 7 in Aplastic Anemia Patients

Even “Moderate” Dose Cyclophosphamide for Severe Aplastic Anemia Is Associated with Significant Toxicities and Does Not Prevent Relapse and Clonal Evolution

Clinical and Genetic Heterogeneity of Telomere Diseases.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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