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Daniel G Tenen, MD
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Journal Articles

Oncofetal Protein SALL4 Is Highly Expressed in Myelodysplastic Syndrome Alongside with NAT10 and P53

Hiro Tatetsu, MD, Miho Watanabe, MD, Emily F Mason, MD PhD, Scott B Lovitch, MDPhD, Kenji Tokunaga, MD, Eisaku Iwanaga, MD, Masao Matsuoka, MDPhD, Daniel G. Tenen, MD, Li Chai, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-134533
Published: 2020
Journal Articles

Core Binding Factor Leukemias Utilize a Physiologic Sense/Antisense Promoter Switch Employed By T-Cells

Emiel van der Kouwe, PharmD, Gerwin Heller, PhD, Akos Czibere, MD, Lucio H. Castilla, PhD, Ruud Delwel, PhD, Annalisa Di Ruscio, MD PhD, Alexander Ebralidze, PhD, Maurizio Forte, MSc, Lukas Kazianka, MD, Christoph Kornauth, Trang Le, BSc, Karin Lind, MSc, Ines Barbosa, PhD, Alexander Pichler, MD, John Pulikkan, PhD, Ann-Sofie Schmolke, MD, Heinz Sill, MD, Wolfgang R. Sperr, MD, Andreas Spittler, MD, Bon Q. Trinh, PhD, Peter Valent, MD, Katrina Vanura, PhD, Robert Welner, PhD, Johannes Zuber, PhD, Daniel G. Tenen, MD, Philipp B. Staber, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-140776
Published: 2020
Journal Articles

Β-Catenin-Tcf/Lef Signaling Promotes Steady State and Emergency Granulopoiesis through G-CSF Receptor Upregulation

Petr Danek, MSc, Miroslava Kardosova, PhD, Lucie Janeckova, PhD, Vladimir Korinek, PhD, Touati Benoukraf, PhD, Daniel G. Tenen, MD, Meritxell Alberich-Jorda
Journal: Blood
Blood (2019) 134 (Supplement_1): 1193.
https://doi.org/10.1182/blood-2019-122254
Published: 2019
Journal Articles

C/Ebpg (CCAAT/Enhancer Binding Protein Gamma) Balances Cytotoxic and Secretory Potential of Natural Killer Cells

Izabela Aparecida Lopes, MSc, Miroslava Kardosova, MSc, Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Cleide Araújo Silva, MSc, Priscila Santos Scheucher, PhD, Daniel G. Tenen, MD, Sanghoon Lee, PhD, Eduardo Magalhães Rego, MD PhD, Robert S. Welner, PhD, Meritxell Alberich-Jorda, Lorena Lobo Figueiredo-Pontes, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3721.
https://doi.org/10.1182/blood-2018-99-119389
Published: 2018
Journal Articles

Cell Type-Specific Deregulation of Polypyrimidine Tract- Binding Proteins (PTBPs) Drive Aberrant Splicing in Multiple Myeloma (MM) and Acute Myeloid Leukemia (AML)

Sophia Adamia, PhD, Sigitas J Verselis, PhD, Teru Hideshima, MD PhD, Michael P. Chu, MD, Shruti Bhatt, PhD, David P. Steensma, MD, Daniel J Deangelo, Richard M. Stone, MD, Daniel G. Tenen, MD, Linda M. Pilarski, PhD, James D. Griffin, MD, Kenneth Anderson, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3895.
https://doi.org/10.1182/blood-2018-99-118501
Published: 2018
Journal Articles

The Lysine Acetyltransferase Tip60 Is Required for Hematopoietic Stem Cell Maintenance

Akihiko Numata, MD, Hui Si Kwok, PhD, Qi-Ling Zhou, Jia Li, PhD, Rebecca Hannah, Jihye Park, PhD, Vladimir Espinosa Angarcia, PhD, Berthold Gottgens, Henry Yang, PhD, John Lough, PhD, Deepak Bararia, PhD, Daniel G. Tenen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2554.
https://doi.org/10.1182/blood-2018-99-118316
Published: 2018
Journal Articles

Long Noncoding RNA Loup Interacts with Runx1 and Regulates Long-Range Transcription of PU.1 in Acute Myeloid Leukemia

Bon Q Trinh, PhD, Pu Zhang, MD, Alexander Ebralidze, PhD, Junyan Zhang, Chan-Shuo Guo, Abby Thurm, Henry Yang, PhD, Ying Li, Annalisa Di Ruscio, MD, Daniel G. Tenen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1281.
https://doi.org/10.1182/blood-2018-99-120252
Published: 2018
Journal Articles

LSD1 Inhibition Exerts Its Anti-Leukemic Effect By Recommissioning PU.1- and C/Ebpα-Dependent Enhancers in AML

Monica Cusan, MD, Sheng Cai, MD PhD, Helai P Mohammad, PhD, Andrei V. Krivtsov, PhD, Alan Chramiec, Evangelia Loizou, Daniel G. Tenen, MD, Min Ye, PhD, Britta Will, PhD, Ulrich G. Steidl, MDPhD, Ryan G. Kruger, PhD, Richard Koche, PhD, Scott Armstrong, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 242.
https://doi.org/10.1182/blood.V130.Suppl_1.242.242
Published: 2017
Journal Articles

Identification of Long Non-Coding RNAs Regulated By the TAL1 Complex in T-Cell Acute Lymphoblastic Leukemia

Shi Hao Tan, PhD, Phuong Cao Thi Ngoc, PhD, Wei Zhong Leong, BSc, Daniel G. Tenen, MD, Takaomi Sanda, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1201.
https://doi.org/10.1182/blood.V130.Suppl_1.1201.1201
Published: 2017
Journal Articles

CARM1/PRMT4 As a Novel Therapeutic Target for AML

Sarah Greenblatt, PhD, Na Man, Pierre-Jacques Hamard, PhD, Concepcion Martinez, B.S., Ye Xu, PhD, Fan Liu, PhD, Justin M Watts, MD, Daniel G. Tenen, MD, Stephen D. Nimer, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 241.
https://doi.org/10.1182/blood.V130.Suppl_1.241.241
Published: 2017
Journal Articles

ARID5B Activates the TAL1-Induced Core Regulatory Circuit and the MYC Oncogene in T-Cell Acute Lymphoblastic Leukemia

Wei Zhong Leong, BSc, Shi Hao Tan, PhD, Phuong Cao Thi Ngoc, PhD, Stella Amanda, Alice Wei Yee Yam, Wei-Siang Liau, Zhiyuan Gong, Lee N. Lawton, PhD, Daniel G. Tenen, MD, Takaomi Sanda, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2502.
https://doi.org/10.1182/blood.V130.Suppl_1.2502.2502
Published: 2017
Journal Articles

Decreased Activity of NK Cells in Myeloproliferative Neoplasms

Adriana Queiroz Arantes, MD, Cristina Tavares Leal, MD, Cleide Araújo Silva, Priscila Santos Scheucher, PhD, Aglair Bergamo, Robert S. Welner, PhD, Daniel G. Tenen, MD, Ann Mullally, MD, Susumu Kobayashi, MD PhD, Eduardo Magalhaes Rego, PhD, Lorena Lobo Figueiredo-Pontes, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 1637.
https://doi.org/10.1182/blood.V126.23.1637.1637
Published: 2015
Journal Articles

C/EBPα and MiR-182 Generate a Negative Feedback Loop Which Is Dysregulated in Acute Myeloid Leukemia

Alexander Arthur Wurm, Dennis Gerloff, Daniela Braeuer-Hartmann, Christiane Katzerke, Jens-Uwe Hartmann, Stephan Fricke, MD, Nadja Hilger, Meritxell Alberich-Jorda, PhD, Daniel G Tenen, MD, Dietger Niederwieser, MD, Gerhard Behre, MD
Journal: Blood
Blood (2014) 124 (21): 776.
https://doi.org/10.1182/blood.V124.21.776.776
Published: 2014
Journal Articles

The G-CSF Induced MiR-143 Targets MAPK-Family Proteins and Is a Prognostic Factor for RIC-Transplanted AML Patients

Jens-Uwe Hartmann, Daniela Braeuer-Hartmann, Dennis Gerloff, Christiane Katzerke, Alexander Arthur Wurm, Carsten Müller-Tidow, MD, Sebastian Schwind, MD, Daniel G. Tenen, MD, Dietger Niederwieser, MD, Gerhard Behre, MD
Journal: Blood
Blood (2014) 124 (21): 2200.
https://doi.org/10.1182/blood.V124.21.2200.2200
Published: 2014
Journal Articles

RUNX1/CBFβ Dosage Is Critical for MLL Leukemias Development

Xiaomei Yan, MD PhD, Yoshihiro Hayashi, MD PhD, Xinghui Zhao, PhD, Aili Chen, PhD, Yue Zhang, MD, Fuhong He, Yunzhu Dong, Yalan Rao, PhD, Bo Li, Rajeana Conway, Alba Maiques-Díaz, Nuomin Huang, Shannon E Elf, Johannes Zuber, MD, Zhijian Xiao, MD, William Tse, Daniel G. Tenen, MD, Qianfei Wang, Wei Chen, James C. Mulloy, PhD, Stephen D Nimer, MD, Gang Huang, PhD
Journal: Blood
Blood (2014) 124 (21): 2187.
https://doi.org/10.1182/blood.V124.21.2187.2187
Published: 2014
Journal Articles

The PML/RARα-Regulated MiR-181a/b-Cluster Targets the Tumor Suppressor RASSF1A in Acute Promyelocytic Leukemia

Daniela Braeuer-Hartmann, Jens-Uwe Hartmann, Dennis Gerloff, Christiane Katzerke, Alexander Arthur Wurm, Maria Vittoria Verga Falzacappa, Pier Guiseppe Pelicci, Carsten Müller-Tidow, MD, Daniel G. Tenen, MD, Dietger Niederwieser, MD, Gerhard Behre, MD
Journal: Blood
Blood (2014) 124 (21): 2195.
https://doi.org/10.1182/blood.V124.21.2195.2195
Published: 2014
Journal Articles

Relationship Between Self-Renewal and Differentiation Pathways in Stem Cells and Leukemia

Robert S Welner, PhD, Danielle E Tenen, BA, Henry Yang, PhD, Deepak Bararia, PhD, Giovanni Amabile, PhD, Daniel G. Tenen, MD
Journal: Blood
Blood (2014) 124 (21): 4789.
https://doi.org/10.1182/blood.V124.21.4789.4789
Published: 2014
Journal Articles

Cellular Reprogramming Erases Aberrant DNA Methylation and the Malignant Phenotype in Chronic Myeloid Leukemia

Giovanni Amabile, PhD, Annalisa Di Ruscio, MDPhD, Fabian Muller, PhD, Robert S Welner, PhD, Henry Yang, PhD, Alexander K Ebralidze, PhD, Hong Zhang, PhD, Lihua Qi, PhD, Giovanni Martinelli, MD, Thijn Brummelkamp, PhD, Michelle M. Le Beau, PhD, Maria E Figueroa, MD, Christoph Bock, PhD, Daniel G Tenen, MD
Journal: Blood
Blood (2014) 124 (21): 4524.
https://doi.org/10.1182/blood.V124.21.4524.4524
Published: 2014
Journal Articles

Conditional Knockout of Sfpi1 in Post GC B and Plasma Cells Induces B Cell Lymphoma and Plasma Cell Neoplasm

Shinya Endo, MD, Hiromichi Yuki, MD PhD, Yoshihiro Komohara, MD PhD, Shikiko Ueno, MD PhD, Nao Nishimura, MD, Niina Ueno, MD, Hiro Tatetsu, MD PhD, Motohiro Takeya, MD PhD, Hiroyuki Hata, MD PhD, Seiji Okada, MD PhD, Daniel G. Tenen, MD, Hiroaki Mitsuya, MD PhD, Yutaka Okuno, MD PhD
Journal: Blood
Blood (2014) 124 (21): 29.
https://doi.org/10.1182/blood.V124.21.29.29
Published: 2014
Journal Articles

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML Regulating Differentiation Block and Self-Renewal

Anetta Ptasinska, PhD, Salam Assi, PhD, Natalia Martinez-Soria, PhD, Maria Rosaria Imperato, PhD, Jason Piper, PhD, Pierre Cauchy, PhD, Anna Pickin, Sally James, PhD, Maarten Hoogenkamp, PhD, Daniel G Tenen, MD, Sascha Ott, PhD, David R Westhead, PhD, Peter N Cockerill, PhD, Olaf Heidenreich, PhD, Constanze Bonifer, PhD
Journal: Blood
Blood (2014) 124 (21): 1061.
https://doi.org/10.1182/blood.V124.21.1061.1061
Published: 2014