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Journal Articles

A New Promising Third Generation CAR-CD30 T-Cell Therapy for CD30+ Lymphoma

Blood (2019) 134 (Supplement_1): 2069.

https://doi.org/10.1182/blood-2019-127969

Published: 2019

Journal Articles

Academic, Phase I/II Trial on T Cells Expressing a Second Generation, CD19-Specific Chimeric Antigen Receptor (CAR) and Inducible Caspase 9 Safety Switch for the Treatment of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) and B-Cell Non-Hodgkin Lymphoma (B-NHL) in Children

Francesca Del Bufalo, MD, Concetta Quintarelli, PhD, Biagio De Angelis, PhD, Ignazio Caruana, PhD, Matilde Sinibaldi, PhD, Luciana Vinti, MD, Pietro Merli, MD, Mattia Algeri, MD, Annalisa Ruggeri, MD, Federica Galaverna, MD, Valentina Cirillo, PhD, Maria Giuseppina Cefalo, MD, Giuseppina Li Pira, PhD, Giovanna Leone, MD, Valentina Bertaina, PhD, Franca Fassio, PhD, Monica Gunetti, PhD, Stefano Iacovelli, PhD, Franco Locatelli, MD PhD

Blood (2019) 134 (Supplement_1): 1341.

https://doi.org/10.1182/blood-2019-129821

Published: 2019

Journal Articles

CD19 Redirected CAR NK Cells Are Equally Effective but Less Toxic Than CAR T Cells

Concetta Quintarelli, PhD, Simona Sivori, PhD, Simona Caruso, PhD, Simona Carlomagno, PhD, Iolanda Boffa, PhDstudent, Domenico Orlando, PhDstudent, Marika Guercio, Biancamaria Cembrola, PhD, Angela Pitisci, Stefano Di Cecca, PhD, Giuseppina Li Pira, PhD, Luciana Vinti, MD, Biagio De Angelis, PhD, Lorenzo Moretta, MD PhD, Franco Locatelli

Blood (2018) 132 (Supplement 1): 3491.

https://doi.org/10.1182/blood-2018-99-118005

Published: 2018

Journal Articles

Phase I-IIa Clinical Trial to Assess Safety and Efficacy of MLM-CAR44.1, a CD44v6 Directed CAR-T in Relapsed/Refractory Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Matteo Giovanni Carrabba, MD, Monica Casucci, PhD, Michael Hudecek, MD, Concetta Quintarelli, PhD, Javier Briones, MD, Roman Hajek, MD PhD, Jorge Sierra, MD, Franco Locatelli, Hermann Einsele, MD PhD, Claudio Bordignon, MD, Fabio Ciceri, MD, Catia Traversari, PhD

Blood (2018) 132 (Supplement 1): 5790.

https://doi.org/10.1182/blood-2018-99-117974

Published: 2018

Journal Articles

Patient-Derived Chimeric Antigen Receptor T-Cell Production Based on a Gammaretroviral Vector Platform Is Not Associated with Generation of CAR+ Leukemia Blasts

Concetta Quintarelli, PhD, Iolanda Boffa, PhDstudent, Matilde Sinibaldi, Domenico Orlando, PhDstudent, Marika Guercio, Stefano Di Cecca, PhD, Simona Caruso, PhD, Angela Pitisci, Valentina Bertaina, Francesca Del Bufalo, MD, Pietro Merli, MD, Mattia Algeri, MD, Federica Galaverna, MD, Luciana Vinti, MD, Giuseppina Li Pira, PhD, Biagio De Angelis, PhD, Franco Locatelli

Blood (2018) 132 (Supplement 1): 2204.

https://doi.org/10.1182/blood-2018-99-119413

Published: 2018

Journal Articles

Alpha/Beta T-Cell and B-Cell Depletion HLA-Haploidentical Hematopoietic Stem Cell Transplantation Is an Effective Treatment for Children/Young Adults with Acute Leukemia

Pietro Merli, MD, Mattia Algeri, MD, Giuseppina Li Pira, PhD, Michela Falco, PhD, Daniela Pende, PhD, Valentina Bertaina, Daria Pagliara, MD PhD, Federica Galaverna, MD, Annalisa Ruggeri, MD PhD, Concetta Quintarelli, PhD, Lorenzo Moretta, MD PhD, Alice Bertaina, MD PhD, Franco Locatelli

Blood (2018) 132 (Supplement 1): 2169.

https://doi.org/10.1182/blood-2018-99-117136

Published: 2018

Journal Articles

T-Cell Depleted HLA-Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (haplo-HSCT) Followed By Donor Lymphocyte Infusion with T Cells Transduced with the Inducible Caspase 9 (iC9) Suicide Gene in Children with Hematological Malignancies

Barbarella Lucarelli, MD, Alice Bertaina, MD PhD, Pietro Merli, MD, Concetta Quintarelli, PhD, Daniela Pende, MD, Michela Falco, PhD, Maria Giuseppina Cefalo, MD, Giuseppina Li Pira, PhD, Ignazio Caruana, PhD, Letizia Pomponia Brescia, MD, Luisa Strocchio, MD, Giuseppe Maria Milano, MD, Valentina Bertaina, PhD, Matilde Sinibaldi, PhD, Mattia Algeri, MD, Lorenzo Moretta, MD, Joanna Stanson, Annemarie Moseley, MD PhD, Franco Locatelli, MD

Blood (2016) 128 (22): 4683.

https://doi.org/10.1182/blood.V128.22.4683.4683

Published: 2016

Journal Articles

BPX-501 Cells (donor T cells transduced with iC9 suicide gene) Are Able to Clear Life-Threatening Viral Infections in Children with Primary Immune Deficiencies Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT)

Barbarella Lucarelli, MD, Pietro Merli, MD, Alice Bertaina, MDPhD, Matilde Sinibaldi, PhD, Stefania Gaspari, MD, Luisa Strocchio, MD, Angela Pitisci, PhD, Giuseppina Li Pira, PhD, Giuseppe Maria Milano, MD, Annemarie Moseley, MDPhD, Concetta Quintarelli, PhD, Franco Locatelli, Prof, MD PhD

Blood (2015) 126 (23): 4299.

https://doi.org/10.1182/blood.V126.23.4299.4299

Published: 2015

Journal Articles

Clinical Outcome after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Results of a Phase I-II Trial

Franco Locatelli, Prof, MD PhD, Pietro Merli, MD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Barbarella Lucarelli, MD, Letizia Pomponia Brescia, MD, Mauro Montanari, MD, Daniela Pende, MD, Michela Falco, PhD, Daria Pagliara, MD, Maria Giuseppina Cefalo, MD, Alessandro Moretta, MD, Concetta Quintarelli, PhD, Brigitte Strahm, MD, Waseem Qasim, MBBS PhD, Mary Slatter, Lorenzo Moretta, MD, Annemarie Moseley, MDPhD, Alice Bertaina, MDPhD

Blood (2015) 126 (23): 1931.

https://doi.org/10.1182/blood.V126.23.1931.1931

Published: 2015

Journal Articles

Immune Reconstitution after Adoptive Infusion of BPX501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Phenotypic and Functional Results of a Phase I-II Trial

Pietro Merli, MD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Matilde Sinibaldi, PhD, Barbarella Lucarelli, MD, Letizia Pomponia Brescia, MD, Giuseppe Palumbo, MD, Giuseppe Maria Milano, MD, Maria Teresa Romano, MD, Valentina Cirillo, PhD, Luisa Strocchio, MD, Irma Airoldi, PhD, Luciana Vinti, MD, Concetta Quintarelli, PhD, Lorenzo Moretta, MD, Annemarie Moseley, MDPhD, Alice Bertaina, MDPhD, Franco Locatelli, Prof, MD PhD

Blood (2015) 126 (23): 3093.

https://doi.org/10.1182/blood.V126.23.3093.3093

Published: 2015

Journal Articles

Bone Marrow (BM) Microenviroment Factors As Early Markers of Response in Patients with Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML-CP) Treated with Nilotinib

Blood (2015) 126 (23): 1570.

https://doi.org/10.1182/blood.V126.23.1570.1570

Published: 2015

Journal Articles

Frequency of a Highly Polymorphic Variant, S36N GFI1 , Is Increased in CML Patients

Jaspal S Kaeda, PhD, Leila Amini, BSc, Concetta Quintarelli, PhD, Iris von Wunsch-Rolshoven, Frauke Ringel, PhD, Michaela Schwarz, MD, Fabrizio Pane, MD, Bernd Dörken, MD, Philipp le Coutre, MD

Blood (2014) 124 (21): 3157.

https://doi.org/10.1182/blood.V124.21.3157.3157

Published: 2014

Journal Articles

A Novel Score to Predict Interferon-Alpha Therapy Responsiveness in Patients with Essential Thrombocythemia

Novella Pugliese, MD Graduate student, Concetta Quintarelli, PhD, Biagio De Angelis, PhD, Laura Cella, PhD, Santa Errichiello, PhD, Luana Marano, Simona Caruso, Graduate student, Nicola Esposito, Barbara Izzo, PhD, Marco Picardi, MD, Vincenzo Martinelli, MD, Fabrizio Pane, MD

Blood (2014) 124 (21): 1850.

https://doi.org/10.1182/blood.V124.21.1850.1850

Published: 2014

Journal Articles

The Interferon Score Towards Interferon Alpha Tailored Therapy In Essential Thrombocythemia

Novella Pugliese, MD, Novella Pugliese, MD, Concetta Quintarelli, PhD, Biagio De Angelis, PhD, Luana Marano, Santa Errichiello, PhD, Nicola Esposito, Maddalena Raia, Claudio Cerchione, Luigi Del Vecchio, MD, Marco Picardi, MD, Vincenzo Martinelli, MD, Fabrizio Pane

Blood (2013) 122 (21): 4073.

https://doi.org/10.1182/blood.V122.21.4073.4073

Published: 2013

Journal Articles

Analysis of Bone Marrow Microenviroment Factors As Early Markers of Response in Patients with Newly Diagnosed Bcr-Abl Positive CML in Chronic Phase Treated with Nilotinib.

Concetta Quintarelli, PhD, Biagio De Angelis, PhD, Santa Errichiello, PhD, Simona Caruso, Nicola Esposito, PhD, Luigia Luciano, MD, Simona Paratore, PhD, Claudia Galimberti, PhD, Simona Soverini, PhD, Carolina Terragna, PhD, Daniela Cilloni, MD, Giuseppe Saglio, MD, Giovanni Martinelli, Frank Giles, MD, Andreas Hochhaus, MD, Fabrizio Pane

Blood (2012) 120 (21): 2795.

https://doi.org/10.1182/blood.V120.21.2795.2795

Published: 2012

Journal Articles

Reduced Expression Level of SHP1 Gives An Additive Survival Advantage to the Ph+ Cells of Chronic Myeloid Leukemia (CML) Patients and Provides a Novel Pretreatment Predictor of Major Molecular Response Achievement in CML Patients.

Blood (2009) 114 (22): 2212.

https://doi.org/10.1182/blood.V114.22.2212.2212

Published: 2009

Journal Articles

Engineering CD19-Redirected T Lymphocytes to Enhance Their Safety and Efficacy

Valentina Hoyos, MD, Barbara Savoldo, MD, Juan F Vera, MD, Concetta Quintarelli, PhD, Cliona M Rooney, PhD, Helen E. Heslop, MD, Malcolm K Brenner, MD, PhD, Gianpietro Dotti, MD

Blood (2008) 112 (11): 824.

https://doi.org/10.1182/blood.V112.11.824.824

Published: 2008

Journal Articles

Safely Improving the in Vivo Survival of Tumor Specific Cytotoxic T Lymphocytes by Co-Transfer of IL7 Receptor Alpha Chain and icaspase9

Juan F Vera, MD, Valentina Hoyos, MD, Barbara Savoldo, MD, Concetta Quintarelli, PhD, Greta A Giordano, Ann M. Leen, PhD, Hao Liu, Aaron E. Foster, PhD, Helen E. Heslop, MD, Cliona M Rooney, PhD, Malcolm K Brenner, MD, PhD, Gianpietro Dotti, MD

Blood (2008) 112 (11): 3534.

https://doi.org/10.1182/blood.V112.11.3534.3534

Published: 2008

Journal Articles

Generation of Epstein Barr Virus Specific Cytotoxic T Lymphocytes (EBVCTLs) Resistant to the Immunosuppressive Drug Tacrolimus (FK506)

Biagio De Angelis, PhD, Gianpietro Dotti, MD, Concetta Quintarelli, PhD, Leslie E Huye, PhD, Lan Zhang, Ming Zhang, Helen E. Heslop, MD, Malcolm K Brenner, MD, PhD, Cliona M Rooney, PhD, Barbara Savoldo, MD

Blood (2008) 112 (11): 3536.

https://doi.org/10.1182/blood.V112.11.3536.3536

Published: 2008

Journal Articles

Polyclonal PRAME-Specific Cytotoxic T Lymphocytes Generated Using Protein-Spanning Pools of Overlapping Pentadecapeptides Target Chronic Myeloid Leukemia

Concetta Quintarelli, PhD, Gianpietro Dotti, MD, Biagio De Angelis, PhD, Valentina Hoyos, MD, Fabrizio Pane, MD, Martha P. Mims, MD, PhD, Helen E. Heslop, MD, Cliona M Rooney, PhD, Malcolm K Brenner, MD, PhD, Barbara Savoldo, MD

Blood (2008) 112 (11): 3899.

https://doi.org/10.1182/blood.V112.11.3899.3899

Published: 2008

NARROW

A New Promising Third Generation CAR-CD30 T-Cell Therapy for CD30+ Lymphoma

Academic, Phase I/II Trial on T Cells Expressing a Second Generation, CD19-Specific Chimeric Antigen Receptor (CAR) and Inducible Caspase 9 Safety Switch for the Treatment of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) and B-Cell Non-Hodgkin Lymphoma (B-NHL) in Children

CD19 Redirected CAR NK Cells Are Equally Effective but Less Toxic Than CAR T Cells

Phase I-IIa Clinical Trial to Assess Safety and Efficacy of MLM-CAR44.1, a CD44v6 Directed CAR-T in Relapsed/Refractory Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Patient-Derived Chimeric Antigen Receptor T-Cell Production Based on a Gammaretroviral Vector Platform Is Not Associated with Generation of CAR+ Leukemia Blasts

Alpha/Beta T-Cell and B-Cell Depletion HLA-Haploidentical Hematopoietic Stem Cell Transplantation Is an Effective Treatment for Children/Young Adults with Acute Leukemia

T-Cell Depleted HLA-Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (haplo-HSCT) Followed By Donor Lymphocyte Infusion with T Cells Transduced with the Inducible Caspase 9 (iC9) Suicide Gene in Children with Hematological Malignancies

BPX-501 Cells (donor T cells transduced with iC9 suicide gene) Are Able to Clear Life-Threatening Viral Infections in Children with Primary Immune Deficiencies Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT)

Clinical Outcome after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Results of a Phase I-II Trial

Immune Reconstitution after Adoptive Infusion of BPX501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Phenotypic and Functional Results of a Phase I-II Trial

Bone Marrow (BM) Microenviroment Factors As Early Markers of Response in Patients with Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML-CP) Treated with Nilotinib

Frequency of a Highly Polymorphic Variant, S36N GFI1 , Is Increased in CML Patients

A Novel Score to Predict Interferon-Alpha Therapy Responsiveness in Patients with Essential Thrombocythemia

The Interferon Score Towards Interferon Alpha Tailored Therapy In Essential Thrombocythemia

Analysis of Bone Marrow Microenviroment Factors As Early Markers of Response in Patients with Newly Diagnosed Bcr-Abl Positive CML in Chronic Phase Treated with Nilotinib.

Reduced Expression Level of SHP1 Gives An Additive Survival Advantage to the Ph+ Cells of Chronic Myeloid Leukemia (CML) Patients and Provides a Novel Pretreatment Predictor of Major Molecular Response Achievement in CML Patients.

Engineering CD19-Redirected T Lymphocytes to Enhance Their Safety and Efficacy

Safely Improving the in Vivo Survival of Tumor Specific Cytotoxic T Lymphocytes by Co-Transfer of IL7 Receptor Alpha Chain and icaspase9

Generation of Epstein Barr Virus Specific Cytotoxic T Lymphocytes (EBVCTLs) Resistant to the Immunosuppressive Drug Tacrolimus (FK506)

Polyclonal PRAME-Specific Cytotoxic T Lymphocytes Generated Using Protein-Spanning Pools of Overlapping Pentadecapeptides Target Chronic Myeloid Leukemia

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American Society of Hematology

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American Society of Hematology

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