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Christoph Lengauer
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Journal Articles

Inhibitory Effects of Midostaurin and Blu-285 on Myeloid Progenitor Cells Derived from Patients with Multi-Mutated KIT D816V+ Advanced Systemic Mastocytosis

Mohamad Jawhar, MD, Nicole Naumann, Sebastian Kluger, Juliana Schwaab, MD, Georgia Metzgeroth, MD, Erica K. Evans, PhD, Alexandra Gardino, PhD, Christoph Lengauer, PhD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Alice Fabarius, PhD, Andreas Reiter, MD
Journal: Blood
Blood (2016) 128 (22): 1964.
https://doi.org/10.1182/blood.V128.22.1964.1964
Published: 2016
Journal Articles

Blu-285, a Potent and Selective Inhibitor for Hematologic Malignancies with KIT Exon 17 Mutations

Erica Evans, PhD, Alexandra Gardino, PhD, Brian Hodous, PhD, Alison Davis, PhD, Julia Zhu, M.S., Nancy E. Kohl, PhD, Christoph Lengauer, PhD
Journal: Blood
Blood (2015) 126 (23): 568.
https://doi.org/10.1182/blood.V126.23.568.568
Published: 2015
Journal Articles

First Selective KIT D816V Inhibitor for Patients with Systemic Mastocytosis

Erica K. Evans, PhD, Brian L. Hodous, PhD, Alexandra Gardino, PhD, Julia Zhu, B.S., Adam Shutes, PhD, Alison Davis, PhD, Joseph Kim, PhD, Kevin Wilson, M.S., Doug Wilson, PhD, Yulian Zhang, PhD, Nancy E. Kohl, PhD, Timothy Guzi, PhD, Christoph Lengauer, PhD
Journal: Blood
Blood (2014) 124 (21): 3217.
https://doi.org/10.1182/blood.V124.21.3217.3217
Published: 2014
Journal Articles

PIM inhibitors target CD25-positive AML cells through concomitant suppression of STAT5 activation and degradation of MYC oncogene

Zhuyan Guo, Anlai Wang, Weidong Zhang, Mikhail Levit, Qiang Gao, Claude Barberis, Michel Tabart, Jingxin Zhang, Dietmar Hoffmann, Dmitri Wiederschain, Jennifer Rocnik, Fangxian Sun, Josh Murtie, Christoph Lengauer, Stefan Gross, Bailin Zhang, Hong Cheng, Vinod Patel, Laurent Schio, Francisco Adrian, Marion Dorsch, Carlos Garcia-Echeverria, Shih-Min A. Huang
Journal: Blood
Blood (2014) 124 (11): 1777–1789.
https://doi.org/10.1182/blood-2014-01-551234
Published: 2014
Includes: Supplemental data