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Carol A. Hegadorn
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Journal Articles

Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation

Yasuaki Shida, Natalia Rydz, David Stegner, Christine Brown, Jeffrey Mewburn, Kate Sponagle, Ozge Danisment, Bredon Crawford, Barbara Vidal, Carol A. Hegadorn, Cynthia M. Pruss, Bernhard Nieswandt, David Lillicrap
Journal: Blood
Blood (2014) 124 (11): 1799–1807.
https://doi.org/10.1182/blood-2013-09-521484
Published: 2014
Journal Articles

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models

Cynthia M. Pruss, Mia Golder, Andrea Bryant, Carol A. Hegadorn, Erin Burnett, Kimberly Laverty, Kate Sponagle, Aly Dhala, Colleen Notley, Sandra Haberichter, David Lillicrap
Journal: Blood
Blood (2011) 117 (16): 4358–4366.
https://doi.org/10.1182/blood-2010-08-303727
Published: 2011
Journal Articles

In Vitro and In Vivo Mouse Models of the Type 1 Von Willebrand Disease Mutations Y1584C and R1205H.

Cynthia M. Pruss, BSc, Kate Sponagle, Kimberly Laverty, Carol A. Hegadorn, Yvette Chirinian, Colleen Notley, Mia Golder, David Lillicrap, MD
Journal: Blood
Blood (2009) 114 (22): 26.
https://doi.org/10.1182/blood.V114.22.26.26
Published: 2009
Journal Articles

Genetically-Engineered Endothelial Cells Implanted Into the Omentum of Hemophilia A Dogs Provides Long-Term Circulating FVIII Resulting From Sustained FVIII Expression and Persistent Cell Viability.

Margareth C Ozelo, M.D., Ph.D., Hideto Matsui, MD, PhD, Carol A. Hegadorn, Lori Harpell, Sandra Powell, James F Hulvat, Ph.D., Andrew Winterborn, DVM, DACLAM, Janine Handforth, BSc, (Hons., Biol), DVM, Christine Hough, PhD, David Lillicrap, MD
Journal: Blood
Blood (2009) 114 (22): 3578.
https://doi.org/10.1182/blood.V114.22.3578.3578
Published: 2009
Journal Articles

Recombinant Protein Infusion and Hydrodynamic Plasmid Delivery Strategies Provide Distinct and Complementary Approaches to the Characterization of Variant Forms of Von Willeband Factor (VWF) in VWF Knockout Mice.

Cynthia M. Pruss, BSc, Carol A. Hegadorn, Andrea Labelle, Erin Burnett, Mia Golder, David Lillicrap, MD
Journal: Blood
Blood (2008) 112 (11): 2020.
https://doi.org/10.1182/blood.V112.11.2020.2020
Published: 2008
Journal Articles

Human von Willebrand Disease Mutations in Mouse von Willebrand Factor Alter Its Cleavage by ADAMTS13.

Cynthia M. Pruss, BSc, Carol A. Hegadorn, MLT, Colleen R.P. Notley, AHT, Rouzbeh Chegeni, PhD, Aly S. Dhala, BScH, David Lillicrap, MD
Journal: Blood
Blood (2007) 110 (11): 2708.
https://doi.org/10.1182/blood.V110.11.2708.2708
Published: 2007
Journal Articles

A novel type 2A von Willebrand factor mutation located at the last nucleotide of exon 26 (3538G>A) causes skipping of 2 nonadjacent exons

Paula D. James, Lee A. O'Brien, Carol A. Hegadorn, Colleen R. P. Notley, Gary D. Sinclair, Christine Hough, Man-Chiu Poon, David Lillicrap
Journal: Blood
Blood (2004) 104 (9): 2739–2745.
https://doi.org/10.1182/blood-2003-12-4286
Published: 2004
Journal Articles

Founder von Willebrand factor haplotype associated with type 1 von Willebrand disease

Lee A. O'Brien, Paula D. James, Maha Othman, Ergul Berber, Cherie Cameron, Colleen R. P. Notley, Carol A. Hegadorn, Jeffrey J. Sutherland, Christine Hough, Georges E. Rivard, Denise O'Shaunessey, David Lillicrap, the Association of Hemophilia Clinic Directors of Canada
Journal: Blood
Blood (2003) 102 (2): 549–557.
https://doi.org/10.1182/blood-2002-12-3693
Published: 2003