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Journal Articles

Preclinical and Clinical Use of AB1, a DNMT1 Protein Depleter, to Upregulate Fetal Hemoglobin in Townes Sickle Cell Disease (SCD) Mice and Patients with SCD

Nirmish Shah, Girindra Raval, Abdullah Kutlar, Niren Patel, Mayuko Takezaki, Biaoru Li, Manickam Alagar, Hongyan Xu, Kelly Blackburn, Santhosh Vadivelu, Robert Schaub, David Santos, Betty Pace
Journal: Blood
Blood (2023) 142 (Supplement 1): 276.
https://doi.org/10.1182/blood-2023-188165
Published: 2023
Journal Articles

Early Effects of a Repurposed Therapeutic PB-04 in Beta Thalassemia Intermedia and in Transgenic Sickle Mice

Betty S. Pace, Seyed Mehdi Nouraie, Kevin H.M. Kuo, Sylvia Singer, Mayuko Takezaki, Biaoru Li, Aidan D Faller, Abdullah Kutlar, Susan P Perrine
Journal: Blood
Blood (2022) 140 (Supplement 1): 5360–5361.
https://doi.org/10.1182/blood-2022-169310
Published: 2022
Journal Articles

Development of the Novel Cytosine Analog Aza-T-Dcyd (AB1) As a Fetal Hemoglobin Inducer to Treat Sickle Cell Disease.

Manickam Alagar, Biaoru Li, Santhosh Vadivelu, Robert Schaub, Chithra D. Palani, Betty S. Pace
Journal: Blood
Blood (2022) 140 (Supplement 1): 4957–4958.
https://doi.org/10.1182/blood-2022-169657
Published: 2022
Journal Articles

Salubrinal Mediated Fetal Hemoglobin Induction through the eIF2α-ATF4 Signaling Pathway

Nicole Hope Lopez, BS, Biaoru Li, MDPhD, Xingguo Zhu, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32.
https://doi.org/10.1182/blood-2020-139969
Published: 2020
Journal Articles

Salubrinal Mediated Fetal Hemoglobin Induction through the eIF2α-ATF4 Signaling Pathway

Nicole Hope Lopez, BS, Biaoru Li, MD PhD, Levi Makala, DVM, MBA, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2235.
https://doi.org/10.1182/blood.V130.Suppl_1.2235.2235
Published: 2017
Journal Articles

Dimethyl Fumarate Induces Fetal Hemoglobin in Sickle Cell Disease

Sriram Krishnamoorthy, PhD, Dipti Gupta, MS, Sarah Sturtevant, Biaoru Li, PhD, Levi C Makala, DVM, MBA, PhD, William E. Hobbs, MDPhD, David R. Light, PhD, Betty Pace, MD
Journal: Blood
Blood (2015) 126 (23): 410.
https://doi.org/10.1182/blood.V126.23.410.410
Published: 2015
Journal Articles

Micro RNA Profiling to Identify Regulator of Fetal Hemoglobin Expression in Sickle Cell Disease

Biaoru Li, PhD, Christina M. Torres, BS, Mayuko Takezaki, MS, Cindy Neunert, MD MSCS, Abdullah Kutlar, MD, Betty S. Pace, MD
Journal: Blood
Blood (2014) 124 (21): 49.
https://doi.org/10.1182/blood.V124.21.49.49
Published: 2014
Journal Articles

Monomethylfumarate (MMF), a Novel Inducer Of Fetal Hemoglobin In Human Erythroid Progenitors and Retinal Pigment Epithelial Cells

Levi Makala, PhD, DVM, Wanwisa Promsote, BS, Biaoru Li, PhD, Vadivel Ganapathy, PhD, Martin Pamela, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2013) 122 (21): 317.
https://doi.org/10.1182/blood.V122.21.317.317
Published: 2013
Journal Articles

Transcription Factor Networks Involved in Fetal Stem Cell Erythropoiesis

Biaoru Li, PhD/MD, Lianghao Ding, PhD, Chinrang Yang, PhD, Michael Story, PhD, Betty S. Pace, MD
Journal: Blood
Blood (2012) 120 (21): 3444.
https://doi.org/10.1182/blood.V120.21.3444.3444
Published: 2012
Journal Articles

Identification of Proteins Involved In Globin Gene Expression During Erythroid Maturation Using An In Vitro Erythroid Liquid Culture System

Biaoru Li, PhD/MD, Lianghao Ding, Wei Li, Tzu-Fang Lou, Michael Story, Betty Pace, MD
Journal: Blood
Blood (2010) 116 (21): 2065.
https://doi.org/10.1182/blood.V116.21.2065.2065
Published: 2010