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Journal Articles

Novel Small-Molecule Inhibitors Targeting Complement Factor D for Therapy of Paroxysmal Nocturnal Hemoglobinuria

B. Paul Morgan, PhD, Jane Thanassi, Steven Podos, PhD, Avinash Phadke, PhD, Venkat Gadhachanda, PhD, Godwin Pais, PhD, Akihiro Hashimoto, PhD, Qiuping Wang, PhD, Dawei Chen, PhD, Xiangzhu Wang, PhD, Atul Agarwal, PhD, Milind Deshpande, PhD, Yongqing Huang, PhD, Jason Wiles, PhD, Mingjun Huang, PhD
Journal: Blood
Blood (2014) 124 (21): 4817.
https://doi.org/10.1182/blood.V124.21.4817.4817
Published: 2014
Journal Articles

A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer

Michelle Elvington, Yuxiang Huang, B. Paul Morgan, Fei Qiao, Nico van Rooijen, Carl Atkinson, Stephen Tomlinson
Journal: Blood
Blood (2012) 119 (25): 6043–6051.
https://doi.org/10.1182/blood-2011-10-383232
Published: 2012
Includes: Supplemental data
Journal Articles

Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNγ-dependent iNOS expression in the vasculature of healthy mice

Jonathan Morton, Barbara Coles, Kate Wright, Awen Gallimore, Jason D. Morrow, Erin S. Terry, Peter B. Anning, B. Paul Morgan, Vincent Dioszeghy, Hartmut Kühn, Pavlos Chaitidis, Adrian J. Hobbs, Simon A. Jones, Valerie B. O'Donnell
Journal: Blood
Blood (2008) 111 (10): 5187–5194.
https://doi.org/10.1182/blood-2007-10-117283
Published: 2008
Journal Articles

Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts

Mark S. Cragg, Suzanne M. Morgan, H. T. Claude Chan, B. Paul Morgan, A. V. Filatov, Peter W. M. Johnson, Ruth R. French, Martin J. Glennie
Journal: Blood
Blood (2003) 101 (3): 1045–1052.
https://doi.org/10.1182/blood-2002-06-1761
Published: 2003
Journal Articles

Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria

Dewi S. Holt, Marina Botto, Anne E. Bygrave, S. Melanie Hanna, Mark J. Walport, B. Paul Morgan
Journal: Blood
Blood (2001) 98 (2): 442–449.
https://doi.org/10.1182/blood.V98.2.442
Published: 2001
Journal Articles

Loxosceles intermedia spider envenomation induces activation of an endogenous metalloproteinase, resulting in cleavage of glycophorins from the erythrocyte surface and facilitating complement-mediated lysis

Denise V. Tambourgi, B. Paul Morgan, Rute M. G. de Andrade, Fábio C. Magnoli, Carmen W. van den Berg
Journal: Blood
Blood (2000) 95 (2): 683–691.
https://doi.org/10.1182/blood.V95.2.683
Published: 2000
Journal Articles

Induction of Decay-Accelerating Factor by Cytokines or the Membrane-Attack Complex Protects Vascular Endothelial Cells Against Complement Deposition

Justin C. Mason, Helen Yarwood, Katharine Sugars, B. Paul Morgan, Kevin A. Davies, Dorian O. Haskard
Journal: Blood
Blood (1999) 94 (5): 1673–1682.
https://doi.org/10.1182/blood.V94.5.1673
Published: 1999
Journal Articles

Deletion of chromosome 20q in myelodysplasia can occur in a multipotent precursor of both myeloid cells and B cells

NJ White, E Nacheva, FA Asimakopoulos, D Bloxham, B Paul, AR Green
Journal: Blood
Blood (1994) 83 (10): 2809–2816.
https://doi.org/10.1182/blood.V83.10.2809.2809
Published: 1994
Journal Articles

Hemoglobin Chesterfield (beta 28 Leu----Arg) produces the phenotype of inclusion body beta thalassemia [letter]

SL Thein, S Best, J Sharpe, B Paul, DJ Clark, MJ Brown
Journal: Blood
Blood (1991) 77 (12): 2791–2793.
https://doi.org/10.1182/blood.V77.12.2791.2791
Published: 1991