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Anton W Langerak, PhD
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Journal Articles

Genome and Exome-Wide Studies Reveal Potential Predictive Efficacy Markers for Venetoclax and Rituximab (VenR) in Relapsed/Refractory Chronic Lymphocytic Leukemia (R/R CLL): Subgroup Analyses of the Murano Trial

Arnon P Kater, MD PhD, Jenny Qun Wu, MS, Julie Dubois, Christopher R Bolen, PhD, Zoe J Assaf, PhD, Peter Hillmen, MD PhD, Barbara F. Eichhorst, MD, Eric F Eldering, PhD, Thomas J. Kipps, MD PhD, Anton W Langerak, PhD, Clemens Mellink, PhD, Anne-Marie Van Der Kevie-Kersemaekers, PhD, Carolyn Owen, MD, Brenda J Chyla, PhD, Elizabeth A Punnoose, PhD, Jue Wang, PhD, Marcus Lefebure, PhD BSc, Michelle Boyer, PhD, Kathryn Humphrey, BSc, Yanwen Jiang, PhD, John F. Seymour, MBBS, PhD FRACP
Journal: Blood
Blood (2019) 134 (Supplement_1): 356.
https://doi.org/10.1182/blood-2019-123678
Published: 2019
Journal Articles

Quantitative Analysis of Minimal Residual Disease (MRD) Shows High Rates of Undetectable MRD after Fixed-Duration Chemotherapy-Free Treatment and Serves As Surrogate Marker for Progression-Free Survival: A Prospective Analysis of the Randomized CLL14 Trial

Kirsten Fischer, MD, Matthias Ritgen, Othman Al-Sawaf, MD, Sandra Robrecht, PhD, Maneesh Tandon, MD, Anna-Maria Fink, MD, Anke Schilhabel, PhD, Thomas Stübig, MD, Monika Brüggemann, MD, Yanwen Jiang, PhD, William Schary, PhD, Barbara F. Eichhorst, MD, Clemens-Martin Wendtner, MD, Eugen Tausch, Karl-Anton Kreuzer, MD PhD, Anton W Langerak, PhD, Valentin Goede, MD, Sebastian Böttcher, MD, Stephan Stilgenbauer, MD, Michael Kneba, PhD, Michael Hallek
Journal: Blood
Blood (2019) 134 (Supplement_1): 36.
https://doi.org/10.1182/blood-2019-125825
Published: 2019
Journal Articles

Euroclonality-NGS DNA Capture Panel for Integrated Analysis of IG/TR Rearrangements, Translocations, Copy Number and Sequence Variation in Lymphoproliferative Disorders

Peter Stewart, PhD, Jana Gazdova, MSc, Nikos Darzentas, PhD, Dorte Wren, PhDFRCPath, Paula Proszek, Grazia Fazio, Simona Songia, Miguel Alcoceba, Maria Eugenia Sarasquete, PhD, Patrick Villarese, PhD, Michèle Y van der Klift, Kim Heezen, Neil McCafferty, MSc, Karol Pal, MSc, Mark Catherwood, PhD, Chang Sik Kim, PhD, Shambhavi Srivastava, PhD, Elizabeth Hodges, PhD, Kostas Stamatopoulos, Wolfram Klapper, Simone Ferrero, MD, Michiel van den Brand, MD, Giovanni Cazzaniga, PhD, Frederic Davi, MD PhD, Ramon Garcia-Sanz, MD PhD, Patricia Groenen, Elizabeth Macintyre, PhDMD, Monika Brüggemann, Christiane Pott, MD PhD, Elisa Genuardi, Anton W Langerak, PhD, David Gonzalez, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 888.
https://doi.org/10.1182/blood-2019-127822
Published: 2019
Journal Articles

Head-To-Head Comparison Of Obinutuzumab (GA101) Plus Chlorambucil (Clb) Versus Rituximab Plus Clb In Patients With Chronic Lymphocytic Leukemia (CLL) and Co-Existing Medical Conditions (Comorbidities): Final Stage 2 Results Of The CLL11 Trial

Valentin Goede, MD, Kirsten Fischer, MD, Raymonde Busch, PhD, Anja Engelke, Barbara Eichhorst, MD, Clemens M Wendtner, MD, Tatiana Chagorova, MD, Javier De la Serna, MD, PhD, Marie-Sarah Dilhuydy, MD, Stephen Opat, MD, Carolyn J. Owen, MD, FRCPC, Olga Samoylova, MD, Karl-Anton Kreuzer, MD, Anton W Langerak, PhD, Matthias Ritgen, MD, Stephan Stilgenbauer, MD, Hartmut Döhner, MD, Elina Asikanius, Kathryn Humphrey, Michael K Wenger, MD, Michael Hallek, MD
Journal: Blood
Blood (2013) 122 (21): 6.
https://doi.org/10.1182/blood.V122.21.6.6
Published: 2013
Journal Articles

Deletion of the Protein Tyrosine Phosphatase Gene PTPN2 in T-Cell Acute Lymphoblastic Leukemia.

Maria Kleppe, Idoya Lahortiga, PhD, Tiama El Chaar, Kim De Keersmaecker, PhD, Nicole Mentens, Carlos Graux, MD, PhD, Katrien Van Roosbroeck, Adolfo A. Ferrando, MD, PhD, Anton W Langerak, PhD, Jules P.P. Meijerink, PhD, Francois Sigaux, MD, Torsten Haferlach, MD, Iwona Wlodarska, PhD, Peter Vandenberghe, MD, PhD, Jean Soulier, MD, PhD, Jan Cools, PhD
Journal: Blood
Blood (2009) 114 (22): 141.
https://doi.org/10.1182/blood.V114.22.141.141
Published: 2009
Journal Articles

Generation of T Cells from Human Embryonic Stem Cells.

Frank Timmermans, MD, Imke Velghe, Lieve Van Walleghem, MD, Magda De Smedt, Stefanie Van Coppernolle, Georges Leclercq, PhD, Tom Taghon, PhD, Harry Moore, PhD, Anton W Langerak, PhD, Tessa C. C. Kerre, MD, PhD, Jean Plum, MD, PhD, Bart Vandekerckhove, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1527.
https://doi.org/10.1182/blood.V112.11.1527.1527
Published: 2008
Journal Articles

Prognostic Significance of Molecular-Cytogenetic Abnormalities in Pediatric T-ALL Is Not Explained by Immunophenotypic Differences.

Martine van Grotel, MSc, Anton W. Langerak, PhD, H. Berna Beverloo, PhD, Jessica G.C.A.M. Buijs-Gladdines, Nicole B. Burger, Max M. van Noesel, MD PhD, Rob Pieters, MD PhD, Jules P.P. Meijerink, PhD
Journal: Blood
Blood (2007) 110 (11): 4220.
https://doi.org/10.1182/blood.V110.11.4220.4220
Published: 2007
Journal Articles

A New Subtype of T-Cell Acute Leukemia in Very Young Children Is Defined by a Translocation Targeting the C-MYB Oncogene, and a Specific Gene Expression Signature.

Emmanuelle Clappier, Wendy Cuccuini, Anna Kalota, Antoine Crinquette, Jean-Michel Cayuela, PhD, Willem A. Dik, PhD, Anton W. Langerak, PhD, Bertrand Montpellier, Bertrand Nadel, PhD, Pierre Walrafen, PhD, Alain Aurias, MD, Thierry Leblanc, MD, Herve Dombret, MD, Alan M. Gewirtz, MD, Andre Baruchel, MD, Francois Sigaux, MD, Jean Soulier, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 982.
https://doi.org/10.1182/blood.V110.11.982.982
Published: 2007
Journal Articles

Identification of a Subgroup of Biphenotypic Myeloid/T-Cell Acute Leukemias with a CEBPA-Mutant Gene Expression Profile, Frequent CEBPA Promoter Hypermethylation and NOTCH1 Mutations.

Bas J. Wouters, MD, Irene Louwers, Claudia A.J. Erpelinck-Verschueren, Peter J.M. Valk, PhD, Dennis Tielemans, Anton W. Langerak, PhD, Daniel G. Tenen, MD PhD, Warren S. Pear, MD PhD, Bob Lowenberg, MD PhD, Ruud Delwel, PhD
Journal: Blood
Blood (2006) 108 (11): 2237.
https://doi.org/10.1182/blood.V108.11.2237.2237
Published: 2006
Journal Articles

CALM-AF10 and HOX11L2 Abnormalities Define Poor Prognostic Subgroups in Pediatric T-Cell Acute Lymphoblastic Leukemia.

Martine van Grotel, MSc, Jules P.P. Meijerink, PhD, Max M. van Noesel, MD, PhD, H. Berna Beverloo, PhD, Anton W. Langerak, PhD, Tim S. Poulsen, PhD, Elisabeth R. van Wering, MD, PhD, E. Gritta Janka-Schaub, MD, PhD, Rob Pieters, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 3279.
https://doi.org/10.1182/blood.V106.11.3279.3279
Published: 2005
Journal Articles

Predictive Value of Gene Expression with Respect to IgVH Mutational Status and Survival in Chronic Lymphocytic Leukemia.

Mars B. Van’t Veer, PhD, Anne Brooymans, Anton W. Langerak, PhD, Wilfried J. Graveland, Kirsten Van Lom, PhD, Peter Valk, PhD
Journal: Blood
Blood (2004) 104 (11): 1913.
https://doi.org/10.1182/blood.V104.11.1913.1913
Published: 2004