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Journal Articles

β 2 -m - a Trigger for NLRP3 Inflammasome Activation within Macrophages Promoting Multiple Myeloma Cell Proliferation

Daniel Hofbauer, Dimitrios Mougiakakos, MD, Maike Büttner-Herold, Frank Neumann, PhD, Jens Nolting, Savita Bisht, Robert Zeiser, MD, Shaima'A Hamarsheh, MSc,BSc, Stefano Ricagno, PhD, Mario Zaiss, Martin Eberhardt, Martin Boettcher, PhD, Katrin Bitterer, Andreas Mackensen, MD, Heiko Bruns, PhD

Blood (2019) 134 (Supplement_1): 2314.

https://doi.org/10.1182/blood-2019-123958

Published: 2019

Journal Articles

Mechanistic Characterization of Tafasitamab-Mediated Antibody-Dependent Cellular Phagocytosis Alone or in Combination with Lenalidomide

Dimitrios Mougiakakos, MD, Simon Voelkl, PhD, Christian Bach, Andrej Stoll, Katrin Bitterer, Fabian Beier, MD, Jan Endell, Rainer Boxhammer, Jörg Thomas Bittenbring, MD, Andreas Mackensen, MD, Heiko Bruns, PhD

Blood (2019) 134 (Supplement_1): 4064.

https://doi.org/10.1182/blood-2019-124886

Published: 2019

Journal Articles

Microenvironmental Triggers Induce a Chemoresistant, Differentiated Subset of S100A8/A9 high AML Cells Via the Jak/STAT3 Signaling Axis

Martin Boettcher, PhD, Konstantinos Panagiotidis, Kristin Mentz, Simon Voelkl, PhD, Heiko Bruns, PhD, Robert Slany, PhD, Andreas Mackensen, MD, Dimitrios Mougiakakos, MD

Blood (2019) 134 (Supplement_1): 2714.

https://doi.org/10.1182/blood-2019-129689

Published: 2019

Journal Articles

Myc -Driven, Primary Mouse Lymphoma Expressing Human CD22 Are Highly Infiltrated By Syngeneic Immune Cells and Provide a Unique Model to Test CD22-Targeted Therapies

Franziska Wagner, Carolin Brandl, Charlotte Emmerich, Andreas Mackensen, MD, Lars Nitschke, Fabian Müller, MD

Blood (2018) 132 (Supplement 1): 1673.

https://doi.org/10.1182/blood-2018-99-110284

Published: 2018

Journal Articles

Human Double-Negative Regulatory T Cells Modulate Effector Functions of Conventional T Cells By Selectively Blocking mTOR Signaling

Tabea Haug, Michael Aigner, PhD, Heiko Bruns, PhD, Moritz Peuser, Dorothea Gebhardt, Jana Berger, Florentine Koppitz, Andreas Mackensen, MD, Simon Voelkl

Blood (2018) 132 (Supplement 1): 2410.

https://doi.org/10.1182/blood-2018-99-112943

Published: 2018

Journal Articles

Characterizing the Immunogenicity of DM-Sensitive and DM-Resistant Antigens

Anna Luise Bernhardt, Sascha Kretschmann, PhD, Judith Bausenwein, Heidi Balzer, Andreas Mackensen, MD, Anita Natalie Kremer, MD PhD

Blood (2018) 132 (Supplement 1): 3310.

https://doi.org/10.1182/blood-2018-99-112103

Published: 2018

Journal Articles

Effect of Proinflammatory and Homeostatic Cytokines on the Functionality of Human Double-Negative Regulatory T Cells

Moritz Peuser, Tabea Haug, Michael Aigner, PhD, Andreas Mackensen, MD, Simon Voelkl

Blood (2018) 132 (Supplement 1): 3726.

https://doi.org/10.1182/blood-2018-99-112977

Published: 2018

Journal Articles

Vaccination after Allogenic Stem Cell Transplantation: Diminished Memory B Cell Response and High Number of Spontaneously IgG Secreting Plasmablasts

Hannes Tittlbach, MD, Andrea Schneider, Corinna Buchstaller, Andreas Mayr, PhD, Ingrid Vasova, MD, Wolf Roesler, MD, Andreas Mackensen, MD, Michael Mach, MD, Thomas H Winkler, PhD, Julia Winkler

Blood (2018) 132 (Supplement 1): 4567.

https://doi.org/10.1182/blood-2018-99-115316

Published: 2018

Journal Articles

Role of N6-Methyladenosine (m6A) RNA Modification in Multiple Myeloma

Christian Bach, Magdalena Leffler, Cindy Flamann, Jan Kronke, Dimitrios Mougiakakos, Andreas Mackensen, MD, Heiko Bruns, PhD

Blood (2018) 132 (Supplement 1): 5601.

https://doi.org/10.1182/blood-2018-99-115820

Published: 2018

Journal Articles

Stroma Cells Promote a S100A8/A9 high -Subset of AML Blasts with Distinct Metabolic Features in a Jak/STAT3-Dependent Manner

Martin Böttcher, Konstantinos Panagiotidis, Andreas Mackensen, MD, Dimitrios Mougiakakos

Blood (2018) 132 (Supplement 1): 2807.

https://doi.org/10.1182/blood-2018-99-114532

Published: 2018

Journal Articles

Human Double-Degative Regulatory T Cells Modulate Differentiation and Function of Conventional T Cells By Disrupting mTOR Activity

Tabea Haug, Heiko Bruns, PhD, Michael Aigner, PhD, Andreas Mackensen, MD, Simon Voelkl, PhD

Blood (2017) 130 (Supplement 1): 3579.

https://doi.org/10.1182/blood.V130.Suppl_1.3579.3579

Published: 2017

Journal Articles

CD33/CD3-Bispecific T-Cell Engaging (BiTE®) Antibody Constructs Efficiently Target Monocytic CD14 + hla-DR low IDO + aml-MDSCs

Dimitrios Mougiakakos, Domenica Saul, Martina Braun, Dr., Sehmus Tohumeken, Roman Kischel, MD, Lutteropp Michael, Dr., Cedric E. Dos Santos, Regina Jitschin, PhDMD, Andreas Mackensen, MD

Blood (2017) 130 (Supplement 1): 1363.

https://doi.org/10.1182/blood.V130.Suppl_1.1363.1363

Published: 2017

Journal Articles

The Addition of Sorafenib to Standard AML Treatment Results in a Substantial Reduction in Relapse Risk and Improved Survival. Updated Results from Long-Term Follow-up of the Randomized-Controlled Soraml Trial

Christoph Rollig, MD MSC, Hubert Serve, Andreas Hüttmann, MD, Richard Noppeney, MD, Carsten Müller-Tidow, Utz Krug, Claudia D. Baldus, MD, Christian H. Brandts, MD, Volker Kunzmann, MD PhD, Hermann Einsele, Alwin Krämer, MD, Kerstin Schäfer-Eckart, MD, Andreas Neubauer, MD, Andreas Burchert, MD, Aristoteles Giagounidis, MD, Stefan W. Krause, Andreas Mackensen, MD, Walter E. Aulitzky, MD, Regina Herbst, MD, Mathias Hänel, MD, Alexander Kiani, Norbert Frickhofen, MD, Johannes Kullmer, Ulrich Kaiser, MD, Hartmut Link, MD PhD, Thomas Geer, MD, Albrecht Reichle, MD, Christian Junghanss, MD, Roland Repp, MD, Frank Heits, MD, Heinz Albert Durk, Thomas Illmer, Martin Bornhäuser, MD, Markus Schaich, MD, Stefani Barbara Parmentier, MD, Martin Goerner, MD, Christian Thiede, MD, Malte von Bonin, MD, Johannes Schetelig, MD, Michael Kramer, M.Sc., Wolfgang E. Berdel, Gerhard Ehninger

Blood (2017) 130 (Supplement 1): 721.

https://doi.org/10.1182/blood.V130.Suppl_1.721.721

Published: 2017

Journal Articles

Adoptive Transfer of Purified Donor-B-Lymphocytes after Allogeneic Stem Cell Transplantation: Results from a Phase I/IIa Clinical Trial

Julia Winkler, MD, Hannes Tittlbach, Wolf Roesler, MD, Julian Strobel, MD, Roland Zimmermann, MD, Stefanie Maas, MD, Bernd Spriewald, MD, Daniel Wolff, MD, Roland Repp, MD, Lambros Kordelas, MD, Michael Mach, PhD, Andreas Mackensen, MD, Thomas H. Winkler, PhD

Blood (2016) 128 (22): 502.

https://doi.org/10.1182/blood.V128.22.502.502

Published: 2016

Journal Articles

Vitamin D Blocks CLL Cell-Mediated MDSC Induction

Dimitrios Mougiakakos, Heiko Bruns, PhD, Martin Böttcher, Mirjeta Qorraj, Mario Fabri, Jochen Dindorf, Leonhard Busch, Regina Jitschin, Andreas Mackensen, MD

Blood (2016) 128 (22): 4355.

https://doi.org/10.1182/blood.V128.22.4355.4355

Published: 2016

Journal Articles

the IKZF1-IRF4 Axis Regulates Macrophage Polarization and Macrophage-Mediated Anti-Tumor Immunity

Heiko Bruns, PhD, Dimitrios Mougiakakos, Christian Bach, Martin Böttcher, Joerg Thomas Bittenbring, MD, Maike Büttner, Kolja Gelse, Michael Rehli, Julia Wimmer, Fabian Beier, MD, Deniz Gezer, Jan Krönke, MD, Heidi Balzer, Stephanie Moi, Bernd Spriewald, MD, Andreas Mackensen, MD, Leonhard Busch

Blood (2016) 128 (22): 2514.

https://doi.org/10.1182/blood.V128.22.2514.2514

Published: 2016

Journal Articles

Indirect Presentation of Y-Chromosome Antigen Dby Is Regulated By Hsc70 and Mediated through CD63 Positive Exosomes

Sascha Kretschmann, Heiko Bruns, PhD, Ursula Schlötzer-Schrehardt, PhD, Andreas Mackensen, MD, Marieke Griffioen, PhD, Anita Kremer

Blood (2016) 128 (22): 3712.

https://doi.org/10.1182/blood.V128.22.3712.3712

Published: 2016

Journal Articles

Hyperactive mTOR Pathway Promotes Lymphoproliferation and Abnormal Differentiation in Human Autoimmune Lymphoproliferative Syndrome

Blood (2015) 126 (23): 1020.

https://doi.org/10.1182/blood.V126.23.1020.1020

Published: 2015

Journal Articles

Lenalidomide Enhances MOR202 Dependent Macrophage-Mediated Effector Functions Via the Vitamin D Pathway

Heiko Bruns, PhD, Regina Jitschin, PhDMD, Dimitrios Mougiakakos, Joerg Thomas Bittenbring, MD, Jens Nolting, Maike Büttner, Michael Rehli, PhD, Julia Wimmer, Frank Neumann, PhD, Christian Bach, Heidi Balzer, Stephanie Moi, Peter Brossart, MD, Armin Gerbitz, MD, Andreas Mackensen, MD

Blood (2015) 126 (23): 2203.

https://doi.org/10.1182/blood.V126.23.2203.2203

Published: 2015

Journal Articles

Interleukin-7 Represses the Immunoregulatory Function of Human TCRαβ+ CD4- CD8- Double-Negative (DN) T Cells By Activating Akt/mTOR Signaling

Andrea Allgaeuer, Armin Gerbitz, MD, Andreas Mackensen, MD, Simon Voelkl, PhD

Blood (2014) 124 (21): 4133.

https://doi.org/10.1182/blood.V124.21.4133.4133

Published: 2014

NARROW

β 2 -m - a Trigger for NLRP3 Inflammasome Activation within Macrophages Promoting Multiple Myeloma Cell Proliferation

Mechanistic Characterization of Tafasitamab-Mediated Antibody-Dependent Cellular Phagocytosis Alone or in Combination with Lenalidomide

Microenvironmental Triggers Induce a Chemoresistant, Differentiated Subset of S100A8/A9 high AML Cells Via the Jak/STAT3 Signaling Axis

Myc -Driven, Primary Mouse Lymphoma Expressing Human CD22 Are Highly Infiltrated By Syngeneic Immune Cells and Provide a Unique Model to Test CD22-Targeted Therapies

Human Double-Negative Regulatory T Cells Modulate Effector Functions of Conventional T Cells By Selectively Blocking mTOR Signaling

Characterizing the Immunogenicity of DM-Sensitive and DM-Resistant Antigens

Effect of Proinflammatory and Homeostatic Cytokines on the Functionality of Human Double-Negative Regulatory T Cells

Vaccination after Allogenic Stem Cell Transplantation: Diminished Memory B Cell Response and High Number of Spontaneously IgG Secreting Plasmablasts

Role of N6-Methyladenosine (m6A) RNA Modification in Multiple Myeloma

Stroma Cells Promote a S100A8/A9 high -Subset of AML Blasts with Distinct Metabolic Features in a Jak/STAT3-Dependent Manner

Human Double-Degative Regulatory T Cells Modulate Differentiation and Function of Conventional T Cells By Disrupting mTOR Activity

CD33/CD3-Bispecific T-Cell Engaging (BiTE®) Antibody Constructs Efficiently Target Monocytic CD14 + hla-DR low IDO + aml-MDSCs

The Addition of Sorafenib to Standard AML Treatment Results in a Substantial Reduction in Relapse Risk and Improved Survival. Updated Results from Long-Term Follow-up of the Randomized-Controlled Soraml Trial

Adoptive Transfer of Purified Donor-B-Lymphocytes after Allogeneic Stem Cell Transplantation: Results from a Phase I/IIa Clinical Trial

Vitamin D Blocks CLL Cell-Mediated MDSC Induction

the IKZF1-IRF4 Axis Regulates Macrophage Polarization and Macrophage-Mediated Anti-Tumor Immunity

Indirect Presentation of Y-Chromosome Antigen Dby Is Regulated By Hsc70 and Mediated through CD63 Positive Exosomes

Hyperactive mTOR Pathway Promotes Lymphoproliferation and Abnormal Differentiation in Human Autoimmune Lymphoproliferative Syndrome

Lenalidomide Enhances MOR202 Dependent Macrophage-Mediated Effector Functions Via the Vitamin D Pathway

Interleukin-7 Represses the Immunoregulatory Function of Human TCRαβ+ CD4- CD8- Double-Negative (DN) T Cells By Activating Akt/mTOR Signaling

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American Society of Hematology

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ASH Publications

American Society of Hematology

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