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Almudena García-Ortiz
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Journal Articles

CRISPR/Cas9 Multi-Editing Enhances CAR NK Cells Therapeutic Potential Against Multiple Myeloma

Eva Castellano, Almudena García-Ortiz, Laura Ugalde, Elena Maroto Martin, Jessica Encinas Mayoral, Raquel Oliva, Laura Garcia-Garcia, Irene Peña, Noemi Álvarez, Gonzalo Carreño, Rosa Ayala, Laura Cordoba, Alejandra Leivas, Guillermo Suñe, Beatriz Martin Antonio, Rafael Alonso Fernandez, Maria Teresa Cedena Romero, Joaquín Martínez-Lopez, Paula Rio, Antonio Valeri
Journal: Blood
Blood (2024) 144 (Supplement 1): 3442.
https://doi.org/10.1182/blood-2024-207942
Published: 2024
Journal Articles

Epigenetic Modifications As a Mechanism of Resistance to BCMA-Directed Immunotherapies in Multiple Myeloma: Insights from Multi-Omic Profiling

Larissa Haertle, Natalia Buenache Cuenda, Isabel Espejo Diaz, Paula Lázaro Del Campo, Andres Arroyo-Barea, Leonie Rieger, Juan Manuel Rosa-Rosa, Rafael Alonso Fernandez, Nieves Lopez, José Sanchez-Pina, Almudena García-Ortiz, Antonio Valeri, Santiago Barrio, Fatima Al-Shahrour, Florian Bassermann, Joaquin Martínez-López, Tomas Di Domenico
Journal: Blood
Blood (2024) 144 (Supplement 1): 5794.
https://doi.org/10.1182/blood-2024-198117
Published: 2024
Journal Articles

Personalized Monitoring of Circulating Tumor DNA By a Specific Signature of Trackable Mutations after Chimeric Antigen Receptor t-Cell Therapy in Non-Hodgkin B Cell Lymphoma

Santiago Barrio, Carolina Martinez-Laperche, Alejandro Martín-Muñoz, Margarita Rodriguez, Laura Rufian, Ismael de la Iglesia, Paula Muñiz Sevilla, Sara Dorado, Ana K Ballesteros, Rebeca Bailen, María Poza, Maria Chicano, Almudena García-Ortiz, Francisco Diaz Crespo, Jose Maria Sanchez Pina, Enrique Revilla, Pilar Sarandeses, Antonio Valeri, Mi Kwon, Joaquin Martinez-Lopez, Ismael Buño Borde, Ana Jimenez Ubieto, Mariana Bastos-Oreiro
Journal: Blood
Blood (2023) 142 (Supplement 1): 6087.
https://doi.org/10.1182/blood-2023-187057
Published: 2023
Journal Articles

CD155 on Multiple Myeloma Cells Is Epigenetically Regulated, Reduce Patients Survival and Compromises the Action of Novel Immunotherapies

Laura Martinez-Verbo, Lorea Villanueva, Pere Llinàs-Arias, Carlos Antonio García-Prieto, David Piñeyro, Aina Oliver-Caldes, Almudena García-Ortiz, Antonio Valeri, Carlos Fernández de Larrea, Joaquin Martinez-Lopez, Gerardo Ferrer, Manel Esteller
Journal: Blood
Blood (2023) 142 (Supplement 1): 6567.
https://doi.org/10.1182/blood-2023-179313
Published: 2023
Journal Articles

Increase of Mitochondrial Activity Contributes to the Bortezomib-Relapsed in Multiple Myeloma, a Novel Therapeutic Opportunity

Alejandra Ortiz-Ruiz, BSc, Yanira Ruiz-Heredia, Mehmet Samur, PhD, Pedro Aguilar-Garrido, Maria Luz Morales, Antonio Valeri, PhD, Almudena Garcia-Ortiz, PhD, Santiago Barrio, PhD, Carmen Bárcena, Rosa Maria Garcia-Martin, Vanesa Garrido, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD, María Teresa Cedena, Joaquin Martinez-Lopez, MD PhD, Maria Linares, PhD, Miguel Gallardo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4408.
https://doi.org/10.1182/blood-2019-123950
Published: 2019
Journal Articles

NKG2D-CAR Transduced Primary Natural Killer Cells Efficiently Target Multiple Myeloma Cells

Alejandra Leivas, PhD BS, MSc, Paula Rio, PhD, Rebeca Mateos, MSc, Mari Liz Paciello, MD, Almudena Garcia-Ortiz, PhD, Lucia Fernandez, PhD, Antonio Perez-Martinez, MD PhD, Dean Anthony Lee, MD PhD, Daniel J. Powell, Jr., PhD, Antonio Valeri, PhD, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 590.
https://doi.org/10.1182/blood-2018-99-114522
Published: 2018