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Journal Articles

Bleeding Risk Reduction in Relation to Predicted Factor IX Levels in Hemophilia B Patients Receiving Idelvion (rIX-FP)

John Roberts, PhD, Cecilia Fosser, PhD, Michael Tortorici, PhD PharmD, Alex Veldman, MD, Iris C. Jacobs, MD, Jagdev Sidhu, PhD
Journal: Blood
Blood (2016) 128 (22): 1411.
https://doi.org/10.1182/blood.V128.22.1411.1411
Published: 2016
Journal Articles

Dosing of Rviii-Singlechain Based on Clinical Bleeding Phenotypes Results in Low Bleeding Rates and Low Consumption in Patients Treated with Prophylaxis Two or Three Times Weekly

Katie St Ledger, Nicole Blackman, Alex Veldman, MD, Ingrid Pabinger, for the Affinity Study Group
Journal: Blood
Blood (2016) 128 (22): 4969.
https://doi.org/10.1182/blood.V128.22.4969.4969
Published: 2016
Journal Articles

Profiling and Comparing the Immunogenicity of a Novel Single-Chain FVIII Molecule (rVIII-SingleChain) for the Treatment of Hemophilia a

Eugene Maraskovsky, PhD, Anne Verhagen, PhD, Huy Huynh, BS, Adriana Baz Morelli, PhD, Stefan Schmidbauer, BS, Sabine Zollner, PhD, Jerry S. Powell, Katie St Ledger, Alex Veldman, MD, Marco Hofmann, MS
Journal: Blood
Blood (2016) 128 (22): 4960.
https://doi.org/10.1182/blood.V128.22.4960.4960
Published: 2016
Journal Articles

Efficacy and safety of rVIII-SingleChain: results of a phase 1/3 multicenter clinical trial in severe hemophilia A

Clinical Trials & Observations
Johnny Mahlangu, Kazimierz Kuliczkowski, Faraizah Abdul Karim, Oleksandra Stasyshyn, Marina V. Kosinova, Lynda Mae Lepatan, Aleksander Skotnicki, Lisa N. Boggio, Robert Klamroth, Johannes Oldenburg, Andrzej Hellmann, Elena Santagostino, Ross I. Baker, Kathelijn Fischer, Joan C. Gill, Stephanie P’Ng, Pratima Chowdary, Miguel A. Escobar, Claudia Djambas Khayat, Luminita Rusen, Debra Bensen-Kennedy, Nicole Blackman, Tharin Limsakun, Alex Veldman, Katie St. Ledger, Ingrid Pabinger, for the AFFINITY Investigators
Journal: Blood
Blood (2016) 128 (5): 630–637.
https://doi.org/10.1182/blood-2016-01-687434
Published: 2016
Includes: Supplemental data
Journal Articles

Rviii-Singlechain Pharmacokinetics and Safety in Children Less Than 12 Years of Age

Claudia Djambas Khayat, MD BS, Oleksandra Stasyshyn, MD, Genadi Iosava, Prof., D.M., Ph. D., Jeannie B Ong, MD, Faraizah Abdul Karim, MD, Debra M. Bensen-Kennedy, MD, Katie St. Ledger, MS, Tharin Limsakun, PhD, Alex Veldman, MD, Ingrid Pabinger, MD
Journal: Blood
Blood (2015) 126 (23): 3524.
https://doi.org/10.1182/blood.V126.23.3524.3524
Published: 2015
Journal Articles

Rviii-Singlechain in Surgical Prophylaxis: Efficacy and Safety of Continuous and Bolus Infusion

Claudia Djambas Khayat, MD BS, Johnny N. Mahlangu, MD, Ross I Baker, MD, Cindy A. Leissinger, MD, Elena Santagostino, MD PhD, Debra M. Bensen-Kennedy, MD, Katie St. Ledger, MS, Alex Veldman, MD, Ingrid Pabinger, MD
Journal: Blood
Blood (2015) 126 (23): 3525.
https://doi.org/10.1182/blood.V126.23.3525.3525
Published: 2015
Journal Articles

Population Pharmacokinetic Modeling and Simulation of Recombinant Single-Chain Factor VIII (r VIII-SingleChain) in Patients with Hemophilia a

Ying Zhang, PhD, Tharin Limsakun, PhD, Debra M. Bensen-Kennedy, MD, Alex Veldman, MD, Zhenling Yao, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2814.
https://doi.org/10.1182/blood.V124.21.2814.2814
Published: 2014