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Journal Articles

Aberrant Cell Cycle Programming Confers Rapid Lethality in the EuSOX11+ CCND1 MCL Mouse Model

Donna R Edwards, MPH, PhD, Pei-yu Kuo, MS, Alessandro Lagana, PhD, Seongjee Park, Pavithra Nedumaran, MS, Violetta Leshchenko, PhD, Stephanie Christie, PhD, Shashidhar Jatiani, PhD, Julie Teruya-Feldstein, MD, Samir Parekh, MD

Blood (2020) 136 (Supplement 1): 6–7.

https://doi.org/10.1182/blood-2020-143038

Published: 2020

Journal Articles

Multidimensional Single Cell Analysis Shows Increased T/NK Cell Subsets in Both Blood and Bone Marrow of Iberdomide (CC-220) Treated Relapsed/Refractory Multiple Myeloma Patients

Michael Amatangelo, Oliver Van Oekelen, MD MSc, Adeeb H Rahman, PhD, Alessandro Lagana, PhD, Sarah Gooding, FRCPath,MRCP,MBBChir, Hervé Avet-Loiseau, MD PhD, Udo Oppermann, PhD, William E Pierceall, PhD, Anjan Thakurta, Samir Parekh, MD

Blood (2019) 134 (Supplement_1): 1775.

https://doi.org/10.1182/blood-2019-126146

Published: 2019

Journal Articles

ADAR1 Drives Disease Progression in Multiple Myeloma By Acting Both As an RNA Editor of Specific Transcripts and As a DNA Mutator of Their Cognate Genes

Rafail Nikolaos Tasakis, MSc, BSc, Alessandro Lagana, PhD, Violetta Leshchenko, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Jonathan J Keats, PhD, Daniel Auclair, Deepu Madduri, MD, Joshua Richter, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, F. Nina Papavasiliou, PhD, Samir Parekh, MD

Blood (2019) 134 (Supplement_1): 3092.

https://doi.org/10.1182/blood-2019-130669

Published: 2019

Journal Articles

A Machine Learning Approach Identifies a 30-Gene Model That Predicts Sensitivity to Selinexor in Multiple Myeloma

Alessandro Lagana, PhD, Sherry Bhalla, Adolfo Aleman, Anna Huo-Chang Mei, MS, Violetta Leshchenko, PhD, Yosef Landesman, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Deepu Madduri, MD, Joshua R Richter, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2019) 134 (Supplement_1): 3101.

https://doi.org/10.1182/blood-2019-130753

Published: 2019

Journal Articles

E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients

Alessandro Lagana, PhD, Seongjee Park, Donna Edwards, Violetta Leshchenko, PhD, Marsha Crochiere, Yosef Landesman, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Deepak Perumal, PhD, Deepu Madduri, MD, Joshua Richter, Ajai Chari, MD, Hearn Jay Cho, MD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2018) 132 (Supplement 1): 3216.

https://doi.org/10.1182/blood-2018-99-116500

Published: 2018

Journal Articles

MAGE-A3 Promotes Chemotherapy Resistance and Proliferation in Multiple Myeloma through Regulation of BIM and p21 Cip1

Hearn Jay Cho, MD, Anna Huo-Chang Mei, MS, Kaity Tung, BS, Jessie Han, Deepak Perumal, PhD, Jonathan J Keats, PhD, Daniel Auclair, PhD, Ajai Chari, MD, Sundar Jagannath, MD, Samir Parekh, MD, Alessandro Lagana, PhD

Blood (2018) 132 (Supplement 1): 4464.

https://doi.org/10.1182/blood-2018-99-118692

Published: 2018

Journal Articles

Increased HLA-E Expression Correlates with Early Relapse in Multiple Myeloma

Blood (2018) 132 (Supplement 1): 59.

https://doi.org/10.1182/blood-2018-99-116828

Published: 2018

Journal Articles

Development of a Neoantigen Prediction Tool for Patient Stratification in Immuno-Oncology Trials

Daniel Duncan, MD, Venkata Thodima, PhD, Jack Yen, MS, Samir Parekh, MD, Alessandro Lagana, PhD, Rita Shaknovich, MD PhD

Blood (2018) 132 (Supplement 1): 2215.

https://doi.org/10.1182/blood-2018-99-119094

Published: 2018

Journal Articles

Clonal Evolution in Newly Diagnosed Multiple Myeloma Patients: A Follow-up Study from the Mmrf Commpass Genomics Project

Alessandro Lagana, PhD, David Melnekoff, BS, MSc, Itai Beno, PhD, Violetta Leshchenko, PhD, Deepak Perumal, PhD, Jonathan J. Keats, PhD, Mary DeRome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2017) 130 (Supplement 1): 325.

https://doi.org/10.1182/blood.V130.Suppl_1.325.325

Published: 2017

Journal Articles

Single-Cell RNA Sequencing Reveals Distinct Transcriptomic Profiles of Multiple Myeloma with Implications for Personalized Medicine

David Melnekoff, BS, MSc, Alessandro Lagana, PhD, Wissam Hamou, PhD, Kimaada Allette, BS, Itai Beno, PhD, Violetta Leshchenko, PhD, Deepak Perumal, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Robert Sebra, PhD, Samir Parekh, MD

Blood (2017) 130 (Supplement 1): 62.

https://doi.org/10.1182/blood.V130.Suppl_1.62.62

Published: 2017

Journal Articles

Adar-Mediated Aberrant a-to-I RNA Editing Is Driven By 1q Amplification and Contributes to Proteasome Inhibitor Resistance in Multiple Myeloma

Alessandro Lagana, PhD, Violetta Leshchenko, PhD, David Melnekoff, BS, MSc, Itai Beno, PhD, Deepak Perumal, PhD, Jonathan Keats, PhD, Mary DeRome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2017) 130 (Supplement 1): 268.

https://doi.org/10.1182/blood.V130.Suppl_1.268.268

Published: 2017

Journal Articles

MAGE-a Inhibits Apoptosis in Multiple Myeloma through Regulation of Bim and PUMA

Hearn Jay Cho, MD PhD, Anna Huo-Chang Mei, MS, Jami Fukui, MD, Kaity Tung, BS, Deepak Perumal, PhD, Violetta Leshchenko, PhD, Alessandro Lagana, PhD, Seunghee Kim-Schultze, PhD, Ajai Chari, Sundar Jagannath, MD, Samir Parekh, MD

Blood (2017) 130 (Supplement 1): 4332.

https://doi.org/10.1182/blood.V130.Suppl_1.4332.4332

Published: 2017

Journal Articles

Aberrant a-to-I RNA Editing and Prognostic Impact of Adar in Multiple Myeloma Patients with 1q Amplification

Alessandro Lagana, PhD, Deepak Perumal, PhD, Violetta V Leshchenko, PhD, Pei-Yu Kuo, MS, Brian Kidd, PhD, Jonathan J Keats, PhD, Mary Derome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2016) 128 (22): 357.

https://doi.org/10.1182/blood.V128.22.357.357

Published: 2016

Journal Articles

Mutation Burden in Multiple Myeloma Is Captured By Gene Expression Profiles

John D Shaughnessy, Jr., PhD, Samir Parekh, MD, Hearn Jay Cho, MD PhD, Alessandro Lagana, PhD, Ajai Chari, MD, Ryan van Laar, PhD, Sundar Jagannath, MD, Bart Barlogie, MD PhD

Blood (2016) 128 (22): 4450.

https://doi.org/10.1182/blood.V128.22.4450.4450

Published: 2016

Journal Articles

MAGE-a Mediate Resistance to Chemotherapy in Multiple Myeloma through Regulation of Bcl-2 Proteins

Hearn Jay Cho, MD PhD, Anna Mei, MS, Jami Fukui, MD, Kaity Tung, BS, Violetta V Leshchenko, PhD, Alessandro Lagana, PhD, Manishkumar Patel, Seunghee Kim-Schulze, PhD, Deepak Perumal, PhD, Ajai Chari, MD, Sundar Jagannath, MD, Samir Parekh, MD

Blood (2016) 128 (22): 3277.

https://doi.org/10.1182/blood.V128.22.3277.3277

Published: 2016

Journal Articles

Integrative Network Analysis of Newly Diagnosed Multiple Myeloma Identifies a Novel RNA-Seq Based High Riskgene Signature

Alessandro Lagana, PhD, Deepak Perumal, PhD, David Melnekoff, BS, Ben Readhead, MBBS, Brian Kidd, PhD, Violetta V Leshchenko, PhD, Pei-Yu Kuo, MS, Jonathan J Keats, PhD, Mary Derome, MS, Jennifer Yesil, MS, Daniel Auclair, PhD, Deepu Madduri, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2016) 128 (22): 3285.

https://doi.org/10.1182/blood.V128.22.3285.3285

Published: 2016

Journal Articles

Network Modeling Reveals CDC42BPA and CLEC11A As Novel Driver Genes of t(4; 14) Multiple Myeloma

Deepak Perumal, PhD, Alessandro Lagana', PhD, David Melnekoff, BS, Ben Readhead, MBBS, Brian Kidd, PhD, Violetta V Leshchenko, PhD, Pei-Yu Kuo, MS, Jennifer Yesil, MS, Mary Derome, MS, Daniel Auclair, PhD, Deepu Madduri, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Bart Barlogie, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2016) 128 (22): 802.

https://doi.org/10.1182/blood.V128.22.802.802

Published: 2016

Journal Articles

SOX11 Cooperates with CCND1 in Mantle Cell Lymphoma Pathogenesis

Pei-Yu Kuo, MS, Zewei Jiang, MD, Deepak Perumal, PhD, Violetta V Leshchenko, PhD, Alessandro Lagana', PhD, Samuel G. Katz, MD PhD, Loren D. Walensky, MD PhD, Rita Shaknovich, MD, PhD, B. Hilda Ye, PhD, Samir Parekh, MD

Blood (2015) 126 (23): 1253.

https://doi.org/10.1182/blood.V126.23.1253.1253

Published: 2015

Journal Articles

A Phase II Study of Panobinostat with Lenalidomide and Weekly Dexamethasone in Myeloma

Blood (2015) 126 (23): 4226.

https://doi.org/10.1182/blood.V126.23.4226.4226

Published: 2015

Journal Articles

Towards a Network-Based Molecular Taxonomy of Newly Diagnosed Multiple Myeloma

Alessandro Lagana, PhD, Ben Readhead, Deepak Perumal, PhD, Brian Kidd, Hearn Jay Cho, MD PhD, Ajai Chari, MD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD

Blood (2015) 126 (23): 840.

https://doi.org/10.1182/blood.V126.23.840.840

Published: 2015

NARROW

Aberrant Cell Cycle Programming Confers Rapid Lethality in the EuSOX11+ CCND1 MCL Mouse Model

Multidimensional Single Cell Analysis Shows Increased T/NK Cell Subsets in Both Blood and Bone Marrow of Iberdomide (CC-220) Treated Relapsed/Refractory Multiple Myeloma Patients

ADAR1 Drives Disease Progression in Multiple Myeloma By Acting Both As an RNA Editor of Specific Transcripts and As a DNA Mutator of Their Cognate Genes

A Machine Learning Approach Identifies a 30-Gene Model That Predicts Sensitivity to Selinexor in Multiple Myeloma

E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients

MAGE-A3 Promotes Chemotherapy Resistance and Proliferation in Multiple Myeloma through Regulation of BIM and p21 Cip1

Increased HLA-E Expression Correlates with Early Relapse in Multiple Myeloma

Development of a Neoantigen Prediction Tool for Patient Stratification in Immuno-Oncology Trials

Clonal Evolution in Newly Diagnosed Multiple Myeloma Patients: A Follow-up Study from the Mmrf Commpass Genomics Project

Single-Cell RNA Sequencing Reveals Distinct Transcriptomic Profiles of Multiple Myeloma with Implications for Personalized Medicine

Adar-Mediated Aberrant a-to-I RNA Editing Is Driven By 1q Amplification and Contributes to Proteasome Inhibitor Resistance in Multiple Myeloma

MAGE-a Inhibits Apoptosis in Multiple Myeloma through Regulation of Bim and PUMA

Aberrant a-to-I RNA Editing and Prognostic Impact of Adar in Multiple Myeloma Patients with 1q Amplification

Mutation Burden in Multiple Myeloma Is Captured By Gene Expression Profiles

MAGE-a Mediate Resistance to Chemotherapy in Multiple Myeloma through Regulation of Bcl-2 Proteins

Integrative Network Analysis of Newly Diagnosed Multiple Myeloma Identifies a Novel RNA-Seq Based High Riskgene Signature

Network Modeling Reveals CDC42BPA and CLEC11A As Novel Driver Genes of t(4; 14) Multiple Myeloma

SOX11 Cooperates with CCND1 in Mantle Cell Lymphoma Pathogenesis

A Phase II Study of Panobinostat with Lenalidomide and Weekly Dexamethasone in Myeloma

Towards a Network-Based Molecular Taxonomy of Newly Diagnosed Multiple Myeloma

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American Society of Hematology

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American Society of Hematology

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