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Abdu I Alayash
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Journal Articles

Mechanism-Based Treatable Targets for Organ Damage and Pain in Sickle Cell Disease

Yugal Goel, Sirsendu Jana, Mya Arellano, Reina A Lomeli, Graham J Velasco, Donovan A Argueta, Richard Prince, Abdu I Alayash, Joel Friedman, Kalpna Gupta
Journal: Blood
Blood (2024) 144 (Supplement 1): 3871.
https://doi.org/10.1182/blood-2024-207867
Published: 2024
Journal Articles

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

John D. Belcher, Chunsheng Chen, Julia Nguyen, Liming Milbauer, Fuad Abdulla, Abdu I. Alayash, Ann Smith, Karl A. Nath, Robert P. Hebbel, Gregory M. Vercellotti
Journal: Blood
Blood (2014) 123 (3): 377–390.
https://doi.org/10.1182/blood-2013-04-495887
Published: 2014
Includes: Supplemental data
Journal Articles

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

Dominik J. Schaer, Paul W. Buehler, Abdu I. Alayash, John D. Belcher, Gregory M. Vercellotti
Journal: Blood
Blood (2013) 121 (8): 1276–1284.
https://doi.org/10.1182/blood-2012-11-451229
Published: 2013
Journal Articles

Plasma Hemoglobin and Heme Trigger Weibel Palade Body Exocytosis and Vaso-Occlusion in Transgenic Sickle Mice

John D Belcher, PhD, Julia Nguyen, Chunsheng Chen, PhD, Ann Smith, PhD, Abdu I Alayash, PhD, DSc, Sethu L Nair, PhD, Arif Somani, MD, Robert P Hebbel, MD, Gregory M Vercellotti, MD
Journal: Blood
Blood (2011) 118 (21): 896.
https://doi.org/10.1182/blood.V118.21.896.896
Published: 2011
Journal Articles

Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification

Paul W. Buehler, Bindu Abraham, Florence Vallelian, Charlotte Linnemayr, Claudia P. Pereira, John F. Cipollo, Yiping Jia, Malgorzata Mikolajczyk, Felicitas S. Boretti, Gabriele Schoedon, Abdu I. Alayash, Dominik J. Schaer
Journal: Blood
Blood (2009) 113 (11): 2578–2586.
https://doi.org/10.1182/blood-2008-08-174466
Published: 2009
Includes: Supplemental data
Journal Articles

CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin

Dominik J. Schaer, Christian A. Schaer, Paul W. Buehler, Robert A. Boykins, Gabriele Schoedon, Abdu I. Alayash, Andreas Schaffner
Journal: Blood
Blood (2006) 107 (1): 373–380.
https://doi.org/10.1182/blood-2005-03-1014
Published: 2006
Includes: Supplemental data
Journal Articles

Redox cycling of diaspirin cross-linked hemoglobin induces G2/M arrest and apoptosis in cultured endothelial cells

Felice D'Agnillo, Abdu I. Alayash
Journal: Blood
Blood (2001) 98 (12): 3315–3323.
https://doi.org/10.1182/blood.V98.12.3315
Published: 2001