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Journal Articles

Inhibition of HIF-1a By PX-478 Normalizes Blood Vessels, Improves Drug Delivery and Suppresses Progression and Dissemination in Multiple Myeloma

Barbara Muz, PhDMSc, Katherine Wasden, Kinan Alhallak, BSc, Amanda Jeske, BS, Feda Azab, Jennifer Sun, BSc, Justin King, BS, Daniel R. Kohnen, MBA, Ravi Vij, MBBS, Abdel Kareem Azab, PhD

Blood (2020) 136 (Supplement 1): 3.

https://doi.org/10.1182/blood-2020-142154

Published: 2020

Journal Articles

Minimal Residual Disease (MRD) Analysis Using Multiparametric Flow Cytometry (MFC) and Identification of Differences in Subpopulations Using Next Generation Sequencing (NGS) in the Bone Marrow (BM) of Multiple Myeloma (MM) Patients (pts)

Sandra M. Dold, MSc, BSc, Veronika Riebl, Dagmar Wider, Marie Follo, PhD, Stefan J. Mueller, Ingrid Bartsch, Milena Pantic, PhD, Cornelius Miething, MD, Chrissoula Kiote-Schmidt, K. Martin Kortüm, MD, Mihaela Zlei, Abdel Kareem Azab, PhD, Mascha Binder, MD, Justyna Rawluk, Justus Duyster, Prof., Robert Zeiser, MD, Ralph Wäsch, MD, Monika Engelhardt, MD

Blood (2018) 132 (Supplement 1): 3222.

https://doi.org/10.1182/blood-2018-99-112489

Published: 2018

Journal Articles

3D-Tissue Engineered Bone Marrow (3DTEBM) Culture Retrospectively Predicts Treatment Clinical Outcomes of Multiple Myeloma Patients

Amanda Jeske, BS, Feda Azab, BPharm, Pilar De La Puente, PhD, Barbara Muz, PhDMSc, Justin King, Daniel R. Kohnen, MBA, Ravi Vij, MBBS, Abdel Kareem Azab, PhD

Blood (2018) 132 (Supplement 1): 1987.

https://doi.org/10.1182/blood-2018-99-118888

Published: 2018

Journal Articles

Overcoming Drug Resistance in Myeloma By Synchronized Delivery of Therapeutic and Bone Marrow Disrupting Agents By Nanoparticles Targeting Tumor-Associated Endothelium

Cinzia Federico, PhD, Barbara Muz, PhDMSc, Jennifer Sun, BSc, Kinan Alhallak, BSc, Justin King, Daniel R. Kohnen, MBA, Mark A. Fiala, BS, Aldo M. Roccaro, MDPhD, Ravi Vij, MBBS, Abdel Kareem Azab, PhD

Blood (2018) 132 (Supplement 1): 1931.

https://doi.org/10.1182/blood-2018-99-118251

Published: 2018

Journal Articles

Enhancing Proteasome-Inhibitory Activity and Specificity of Bortezomib By Endocytosis-Mediated Uptake of CD38 Targeted Nanoparticles in Multiple Myeloma

Pilar De La Puente, PhD M.Sc, Abbey Jin, Micah John Luderer, BS, MS, Christopher Egbulefu, Barbara Muz, PhDMSc, Cinzia Federico, PhD, Justin King, Daniel Kohnen, Noha Nabil Salama, PhD, Samuel Achilefu, Ravi Vij, MDMBA, Abdel Kareem Azab, PhD

Blood (2017) 130 (Supplement 1): 1876.

https://doi.org/10.1182/blood.V130.Suppl_1.1876.1876

Published: 2017

Journal Articles

Plasma-Derived 3D Culture for Leukemic Proliferation

Pilar De La Puente, PhD M.Sc, Ryan Soo Hoo, Michael P Rettig, PhD, Noha Nabil Salama, PhD, John F DiPersio, MD PhD, Abdel Kareem Azab, PhD

Blood (2017) 130 (Supplement 1): 3831.

https://doi.org/10.1182/blood.V130.Suppl_1.3831.3831

Published: 2017

Journal Articles

Targeting CD47 As a Novel Therapeutic Strategy in Multiple Myeloma

Barbara Muz, PhDMSc, Hubert D Kusdono, Justin King, Daniel Kohnen, Mark A. Fiala, BS, Ravi Vij, MDMBA, Ben Capoccia, PhD, Pamela T. Manning, PhD, Noha Nabil Salama, PhD, Abdel Kareem Azab, PhD

Blood (2017) 130 (Supplement 1): 3099.

https://doi.org/10.1182/blood.V130.Suppl_1.3099.3099

Published: 2017

Journal Articles

3D-Tissue Engineered Bone Marrow (3DTEBM) Culture Predicts Clinical Efficacy of Drugs Better Than Regular Culture Systems in Multiple Myeloma

Amanda Jeske, BS, Abdel Kareem Azab, PhD

Blood (2017) 130 (Supplement 1): 3147.

https://doi.org/10.1182/blood.V130.Suppl_1.3147.3147

Published: 2017

Journal Articles

Epigenetic Modifications of the Bone Marrow (BM) Niche in Multiple Myeloma (MM) - a Three-Dimensional (3D) in Vitro Approach

Stefan J. Müller, PharmD, Dagmar Wider, Andreas R. Thomsen, MD, Marie Follo, PhD, Johannes M. Waldschmidt, MD, Gabriele Ihorst, Sandra M. Dold, MSc, Julia Felthaus, Johanna Senger, PhD, Julia Schüler, DVM, Justus Duyster, Abdel Kareem Azab, PhD, Martin J. Hug, PhD, Manfred Jung, PhD, Ralph Wäsch, MD, Monika Engelhardt

Blood (2017) 130 (Supplement 1): 1793.

https://doi.org/10.1182/blood.V130.Suppl_1.1793.1793

Published: 2017

Journal Articles

Class I PI3K Isoforms Exert a Differential Role On Survival and Cell Trafficking In Multiple Myeloma

Ilyas Sahin, MD, Feda Azab, Michele Moschetta, MD, Yuji Mishima, PhD, Brian Tsang, Patricia Maiso, PhD, Antonio Sacco, BS, Aldo M Roccaro, MD, PhD, Abdel Kareem Azab, PhD, BSPharm, Irene M. Ghobrial, MD

Blood (2013) 122 (21): 3159.

https://doi.org/10.1182/blood.V122.21.3159.3159

Published: 2013

Journal Articles

CXCR4 Monoclonal Antibody, BMS-936564 (MDX-1338), Modulates Epithelial to Mesenchymal Transition (EMT) in Multiple Myeloma Cells

Aldo M Roccaro, MD, PhD, Antonio Sacco, BS, Michelle R. Kuhne, PhD, Abdel Kareem Azab, PhD, BSPharm, Patricia Maiso, PhD, Feda Azab, BPharm, Salomon Manier, MD, Yosra Aljaway, BS, Michaela R Reagan, PhD, Lewis Cohen, MD, MS, Pina M Cardarelli, Ph.D., Irene M. Ghobrial, MD

Blood (2012) 120 (21): 4009.

https://doi.org/10.1182/blood.V120.21.4009.4009

Published: 2012

Journal Articles

Deregulation of TNFRSF18 (GITR) Through Promoter CpG Island Methylation Induces Tumor Proliferation in Multiple Myeloma

Yang Liu, PhD, Yong Zhang, PhD, Phong Quang, BS, Hai T Ngo, BS, Feda Azab, BPharm, Abdel Kareem Azab, PhD, BSPharm, Brittany Morgan, Patricia Maiso, PhD, Michaela Reagan, PhD, Christopher P. Rombaoa, Antonio Sacco, BS, Aldo M Roccaro, MD, PhD, Ruben Carrasco, MD, PhD, Irene M. Ghobrial, MD

Blood (2011) 118 (21): 2424.

https://doi.org/10.1182/blood.V118.21.2424.2424

Published: 2011

Journal Articles

LNA Anti-MicroRNA-155: A Novel Therapeutic Strategy in Waldenstrom Macroglobulinemia and Chronic Lymphocytic Leukemia

Blood (2011) 118 (21): 2728.

https://doi.org/10.1182/blood.V118.21.2728.2728

Published: 2011

Journal Articles

Dissecting the role of CXCR7 in Cell Trafficking of Endothelial-Cells and Endothelial-Progenitor-Cells in Multiple Myeloma,

Abdel Kareem Azab, PhD, BSPharm, Feda Azab, BPharm, Phong Quang, Patricia Maiso, PhD, Hai T Ngo, BS, Johann Zimmermann, Kalpana Patel, Barbara Romagnoli, Antonio Sacco, BS, Yang Liu, PhD, Yong Zhang, PhD, Michaela Reagan, PhD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2011) 118 (21): 3934.

https://doi.org/10.1182/blood.V118.21.3934.3934

Published: 2011

Journal Articles

Stroma-Derived Exosomes Mediate Oncogenesis in Multiple Myeloma

Aldo M Roccaro, MD, PhD, Antonio Sacco, BS, Abdel Kareem Azab, PhD, Yu-Tzu Tai, PhD, Patricia Maiso, PhD, Yong Zhang, PhD, Yang Liu, PhD, Michaela Reagan, PhD, Feda Azab, BPharm, Ghayas C Issa, MD, Hai T Ngo, BS, Phong Quang, BS, Kenneth C Anderson, MD, Riccardo Dalla-Favera, Irene M. Ghobrial, MD

Blood (2011) 118 (21): 625.

https://doi.org/10.1182/blood.V118.21.625.625

Published: 2011

Journal Articles

The Role of PI3K Signaling in Cell Trafficking of Multiple Myeloma

Feda Azab, BPharm, Abdel Kareem Azab, PhD, BSPharm, Patricia Maiso, PhD, Phong Quang, Hai T Ngo, BS, Antonio Sacco, BS, Yang Liu, PhD, Yong Zhang, PhD, Michaela Reagan, PhD, Aldo M Roccaro, MD, PhD, Irene M. Ghobrial, MD

Blood (2011) 118 (21): 1804.

https://doi.org/10.1182/blood.V118.21.1804.1804

Published: 2011

Journal Articles

Role of TORC1 and TORC2 in Multiple Myeloma

Patricia Maiso, PhD, Yi Liu, PhD, Abdel Kareem Azab, PhD, BSPharm, Brittany Morgan, Feda Azab, BPharm, Antonio Sacco, BS, Michaela Reagan, PhD, Hai T Ngo, BS, Yang Liu, PhD, Yong Zhang, PhD, Charles Lin, PhD, Aldo M Roccaro, MD, PhD, Christian Rommel, PhD, Irene M. Ghobrial, MD

Blood (2011) 118 (21): 1815.

https://doi.org/10.1182/blood.V118.21.1815.1815

Published: 2011

Journal Articles

Hypoxia Promotes Dissemination of Multiple Myeloma Through Acquisition of Endothelial to Mesenchymal Transition (EMT) Features

Abdel Kareem Azab, PhD, BSPharm, Jinsong Hu, Phong Quang, BS, Feda Azab, BPharm, Costas Pitsillides, Brian Thompson, Patricia Maiso, PhD, Aldo M Roccaro, MD, PhD, Antonio Sacco, BS, Hai T Ngo, BS, Ghayas C. Issa, MD, Charles Lin, PhD, Andrew L. Kung, MD, PhD, Karin Vanderkerken, Irene M. Ghobrial, MD

Blood (2011) 118 (21): 471.

https://doi.org/10.1182/blood.V118.21.471.471

Published: 2011

Journal Articles

Selective Inhibition of the Chymotrypsin-Like Activity of the Immunoproteasome and Constitutive Proteasome Represents a Valid Anti-Tumor Strategy in Waldenstrom Macroglobulinemia.

Aldo M. Roccaro, MD, PhD, Antonio Sacco, Monette Aujay, Hai Ngo, Feda Azab, BPharm, Abdel Kareem Azab, PhD, BPharm, Molly Melhem, Judith M. Runnels, PhD, Phong Quang, Susan Demo, PhD, Irene Ghobrial, M.D.

Blood (2009) 114 (22): 4911.

https://doi.org/10.1182/blood.V114.22.4911.4911

Published: 2009

Journal Articles

Gene Transcriptional Activity Analysis in the 6q Region in Waldenstrom Macroglobulinemia (WM) Using ChIP-on-Chip Technology

Xavier Leleu, MD, PhD, Fangxin Hong, PhD, Aldo M. Roccaro, MD, PhD, Xiaoying Jia, Antonio Sacco, Anne-Sophie Moreau, MD, Hai Ngo, Abdel kareem Azab, PhD, Feda Azab, Molly Melhem, Kenneth C. Anderson, MD, Irene M. Ghobrial, MD

Blood (2008) 112 (11): 628.

https://doi.org/10.1182/blood.V112.11.628.628

Published: 2008

NARROW

Inhibition of HIF-1a By PX-478 Normalizes Blood Vessels, Improves Drug Delivery and Suppresses Progression and Dissemination in Multiple Myeloma

Minimal Residual Disease (MRD) Analysis Using Multiparametric Flow Cytometry (MFC) and Identification of Differences in Subpopulations Using Next Generation Sequencing (NGS) in the Bone Marrow (BM) of Multiple Myeloma (MM) Patients (pts)

3D-Tissue Engineered Bone Marrow (3DTEBM) Culture Retrospectively Predicts Treatment Clinical Outcomes of Multiple Myeloma Patients

Overcoming Drug Resistance in Myeloma By Synchronized Delivery of Therapeutic and Bone Marrow Disrupting Agents By Nanoparticles Targeting Tumor-Associated Endothelium

Enhancing Proteasome-Inhibitory Activity and Specificity of Bortezomib By Endocytosis-Mediated Uptake of CD38 Targeted Nanoparticles in Multiple Myeloma

Plasma-Derived 3D Culture for Leukemic Proliferation

Targeting CD47 As a Novel Therapeutic Strategy in Multiple Myeloma

3D-Tissue Engineered Bone Marrow (3DTEBM) Culture Predicts Clinical Efficacy of Drugs Better Than Regular Culture Systems in Multiple Myeloma

Epigenetic Modifications of the Bone Marrow (BM) Niche in Multiple Myeloma (MM) - a Three-Dimensional (3D) in Vitro Approach

Class I PI3K Isoforms Exert a Differential Role On Survival and Cell Trafficking In Multiple Myeloma

CXCR4 Monoclonal Antibody, BMS-936564 (MDX-1338), Modulates Epithelial to Mesenchymal Transition (EMT) in Multiple Myeloma Cells

Deregulation of TNFRSF18 (GITR) Through Promoter CpG Island Methylation Induces Tumor Proliferation in Multiple Myeloma

LNA Anti-MicroRNA-155: A Novel Therapeutic Strategy in Waldenstrom Macroglobulinemia and Chronic Lymphocytic Leukemia

Dissecting the role of CXCR7 in Cell Trafficking of Endothelial-Cells and Endothelial-Progenitor-Cells in Multiple Myeloma,

Stroma-Derived Exosomes Mediate Oncogenesis in Multiple Myeloma

The Role of PI3K Signaling in Cell Trafficking of Multiple Myeloma

Role of TORC1 and TORC2 in Multiple Myeloma

Hypoxia Promotes Dissemination of Multiple Myeloma Through Acquisition of Endothelial to Mesenchymal Transition (EMT) Features

Selective Inhibition of the Chymotrypsin-Like Activity of the Immunoproteasome and Constitutive Proteasome Represents a Valid Anti-Tumor Strategy in Waldenstrom Macroglobulinemia.

Gene Transcriptional Activity Analysis in the 6q Region in Waldenstrom Macroglobulinemia (WM) Using ChIP-on-Chip Technology

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American Society of Hematology

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American Society of Hematology

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