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Journal Articles

Very long chain fatty acid metabolism is required in acute myeloid leukemia

Matthew Tcheng, Alessia Roma, Nawaz Ahmed, Richard W. Smith, Preethi Jayanth, Mark D. Minden, Aaron D. Schimmer, David A. Hess, Kristin Hope, Kevin A. Rea, Tariq A. Akhtar, Eric Bohrnsen, Angelo D’Alessandro, Al-Walid Mohsen, Jerry Vockley, Paul A. Spagnuolo

Blood (2021) 137 (25): 3518–3532.

https://doi.org/10.1182/blood.2020008551

Published: 2021

Includes: Supplemental data

Journal Articles

International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia

Blood (2020) 135 (21): 1859–1869.

https://doi.org/10.1182/blood.2019003453

Published: 2020

Includes: Supplemental data

Journal Articles

PU.1 and Spi-B Oppose Transformation Of Pre-B Cells Through Activation Of Key Genes Involved In B Cell Receptor Signalling

Darah A. Christie, PhD, Shereen A. Turkistany, Li S. Xu, PhD, Stephen K. H. Li, Ian Welch, DVM, Heather C. Broughton, Gillian I. Bell, David A. Hess, PhD, Rodney P. DeKoter, PhD

Blood (2013) 122 (21): 3737.

https://doi.org/10.1182/blood.V122.21.3737.3737

Published: 2013

Journal Articles

Multiple Human Progenitor Lineages Mediate the Endogenous Regeneration of Beta Cells Via Pro-Angiogenic and Putative Neogenic Function.

Gillian I Bell, Debra L Robson, Heather C Broughton, Anargyros Xenocostas, MD, FRCPC, David A Hess, PhD

Blood (2009) 114 (22): 2426.

https://doi.org/10.1182/blood.V114.22.2426.2426

Published: 2009

Journal Articles

Augmented Revascularization and Recovery From Acute Limb Ischemia After Transplantation of Human Umbilical Cord Blood Progenitor Cells with High Aldehyde Dehydrogenase Activity.

David M Putman, Heather C Broughton, Debra L Robson, Gillian I Bell, David A Hess, PhD

Blood (2009) 114 (22): 3042.

https://doi.org/10.1182/blood.V114.22.3042.3042

Published: 2009

Journal Articles

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity

Benjamin J. Capoccia, Debra L. Robson, Krysta D. Levac, Dustin J. Maxwell, Sarah A. Hohm, Marian J. Neelamkavil, Gillian I. Bell, Anargyros Xenocostas, Daniel C. Link, David Piwnica-Worms, Jan A. Nolta, David A. Hess

Blood (2009) 113 (21): 5340–5351.

https://doi.org/10.1182/blood-2008-04-154567

Published: 2009

Includes: Supplemental data

Journal Articles

Liver Engraftment by Transplanted Human Progenitor Cells with High Aldehyde Dehydrogenase Activity in a Novel Model, NOD/SCID/MPSVII Mice.

Ping Zhou, PhD, Sara Hohm, David A. Hess, PhD, Jan A. Nolta, PhD

Blood (2007) 110 (11): 434.

https://doi.org/10.1182/blood.V110.11.434.434

Published: 2007

Journal Articles

Aldehyde Dehydrogenase-Activity Purifies Multiple Hemangiogenic Lineages That Accelerate Vascularization of Ischemic Tissue through Paracrine Support of Neovessel Formation.

Krysta D. Levac, PhD, Debra L. Robson, BSC, Marian J. Neelamkavil, BSc, Sarah A. Hohm, BSc, Benjamin J. Capoccia, BSc, Daniel C. Link, MD, Jan A. Nolta, PhD, David A. Hess, PhD

Blood (2007) 110 (11): 3716.

https://doi.org/10.1182/blood.V110.11.3716.3716

Published: 2007

Journal Articles

A Prognostic Score for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma: Analysis of 2189 Patients.

Apostolia-Maria Tsimberidou, MD, PhD, Peter McLaughlin, M.D., Susan O’Brien, M.D., Sijin Wen, M.S., William G. Wierda, M.D., Ph.D., John Manning, M.D., Susan Lerner, M.S., Mark A. Hess, Hagop Kantarjian, M.D., Emil J. Freireich, M.D., Michael J. Keating, M.D.

Blood (2006) 108 (11): 2783.

https://doi.org/10.1182/blood.V108.11.2783.2783

Published: 2006

Journal Articles

Genomic Aberrations in Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma by Absolute Lymphocyte Count: Analysis of 1694 Patients.

Apostolia-Maria Tsimberidou, MD, PhD, Peter McLaughlin, M.D., Susan O’Brien, M.D., Sijin Wen, M.S., William G. Wierda, M.D., Ph.D., John T. Manning, M.D., Lynne V. Abruzzo, M.D., Ph.D., Susan Lerner, M.S., Mark A. Hess, B.B.A., Hagop M. Kantarjian, M.D., Emil J. Freireich, M.D., Michael J. Keating, M.D.

Blood (2006) 108 (11): 4958.

https://doi.org/10.1182/blood.V108.11.4958.4958

Published: 2006

Journal Articles

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells

David A. Hess, Louisa Wirthlin, Timothy P. Craft, Phillip E. Herrbrich, Sarah A. Hohm, Ryan Lahey, William C. Eades, Michael H. Creer, Jan A. Nolta

Blood (2006) 107 (5): 2162–2169.

https://doi.org/10.1182/blood-2005-06-2284

Published: 2006

Journal Articles

Human CD34+Cells Mobilized by AMD3100 Demonstrate Enhanced NOD/SCID Repopulating Function Compared to CD34+ Cells Mobilized by Granulocyte Colony Stimulating Factor.

David A. Hess, PhD, Louisa Wirthlin, BA, Timothy P. Craft, BS, Jesper Bonde, PhD, Ryan W. Lahey, Sarah A. Hohm, BS, Phillip E. Herrbrich, BS, John F. DiPersio, MD, Steven M. Devine, MD, Jan A. Nolta, PhD

Blood (2005) 106 (11): 1962.

https://doi.org/10.1182/blood.V106.11.1962.1962

Published: 2005

Journal Articles

Comparison of Human Stem Cell Homing after Intravenous or Intra-Femoral Transplantation Using Multimodal In Vivo Imaging of Repopulating Human CD34+ Cells Labeled with Far-Red Fluorescent-Conjugated Nanoparticles.

Jesper Bonde, PhD, David A. Hess, PhD, Dustin J. Maxwell, PhD, Ryan Lahey, BS, Michael H. Creer, MD, David Piwnica-Worms, PhD, Jan A. Nolta, PhD

Blood (2005) 106 (11): 2196.

https://doi.org/10.1182/blood.V106.11.2196.2196

Published: 2005

Journal Articles

Bone Marrow-Derived Aldehyde Dehdrogenase Expressing Cells Possess Endothelial Progenitor Function in Addition to Hematopoietic Repopulating Ability and Aid in Blood Flow Recovery after Acute Ischemic Injury.

Benjamin J. Capoccia, BSc, Louisa Wirthlin, BSc, Rebecca Shepherd, MD, Kevin O’Dell, Jan A. Nolta, PhD, Daniel C. Link, MD, David A. Hess, PhD

Blood (2005) 106 (11): 2663.

https://doi.org/10.1182/blood.V106.11.2663.2663

Published: 2005

Journal Articles

In Vivo Imaging and Tracking of Defined, Repopulating Human Stem Cell Subsets Using Fluorescence Conjugated Nanoparticles in a Clinically Applicable Ex Vivo Protocol.

Jesper Bonde, PhD, Dustin J. Maxwell, PhD, David A. Hess, PhD, Ryan Lahey, BS, Michael H. Creer, MD, David Piwnica-Worms, PhD, Jan A. Nolta, PhD

Blood (2005) 106 (11): 3031.

https://doi.org/10.1182/blood.V106.11.3031.3031

Published: 2005

Journal Articles

Transplanted Human Aldehyde Dehydrogenase Expressing Stem Cells Circulate and Engraft Nonhematopoietic Tissues.

David A. Hess, PhD, Louisa Wirthlin, BS, Timothy C. Craft, BS, Phillip E. Herrbrich, BS, Marie Roberts, BS, Michael H. Creer, MD, Mark S. Sands, PhD, Jan A. Nolta, PhD

Blood (2005) 106 (11): 1693.

https://doi.org/10.1182/blood.V106.11.1693.1693

Published: 2005

Journal Articles

A Pilot Study Evaluating the Safety and Efficacy of AMD3100 for the Mobilization and Transplantation of HLA-Matched Sibling Donor Hematopoietic Stem Cells in Patients with Advanced Hematological Malignancies.

Steven M. Devine, MD, Jesper Bonde, PhD, David A. Hess, PhD, Terri M. Edwards, Daniel C. Link, MD, Diane Sempek, Gary Calandra, MD, Karin Badel, Jan A. Nolta, MD, John F. DiPersio, MD, PhD

Blood (2004) 104 (11): 3341.

https://doi.org/10.1182/blood.V104.11.3341.3341

Published: 2004

Journal Articles

Transplantation of Human Aldehyde Dehydrogenase Expressing Cells Leads to Widespread Tissue Distribution of Donor Cells in the Novel NOD/SCID/MPSVII Xenotransplantation Model.

David A. Hess, PhD, Timothy P. Craft, BS, Louisa Wirthlin, BS, Phillip E. Herrbrich, BS, A. Alex Hofling, PhD, Mark S. Sands, PhD, Jan A. Nolta, PhD

Blood (2004) 104 (11): 3601.

https://doi.org/10.1182/blood.V104.11.3601.3601

Published: 2004

Journal Articles

Isolation of Human CD34 - Cells with High Aldehyde Dehydrogenase Activity Reveals a Novel Population with Hematopoietic Repopulating Potential.

David A. Hess, PhD, Phillip E. Herrbrich, BS, Louisa Wirthlin, BS, Timothy P. Craft, BS, Jan A. Nolta, PhD

Blood (2004) 104 (11): 3214.

https://doi.org/10.1182/blood.V104.11.3214.3214

Published: 2004

Journal Articles

CD133-Expressing Cells with High Aldehyde Dehydrogenase Activity Represent a Primitive Human Hematopoietic Stem Cell Population with Enhanced Repopulating Potential.

David A. Hess, PhD, Louisa Wirthlin, BS, Timothy P. Craft, BS, Todd E. Meyerrose, BS, Jan A. Nolta, PhD

Blood (2004) 104 (11): 250.

https://doi.org/10.1182/blood.V104.11.250.250

Published: 2004

NARROW

Very long chain fatty acid metabolism is required in acute myeloid leukemia

International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia

PU.1 and Spi-B Oppose Transformation Of Pre-B Cells Through Activation Of Key Genes Involved In B Cell Receptor Signalling

Multiple Human Progenitor Lineages Mediate the Endogenous Regeneration of Beta Cells Via Pro-Angiogenic and Putative Neogenic Function.

Augmented Revascularization and Recovery From Acute Limb Ischemia After Transplantation of Human Umbilical Cord Blood Progenitor Cells with High Aldehyde Dehydrogenase Activity.

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity

Liver Engraftment by Transplanted Human Progenitor Cells with High Aldehyde Dehydrogenase Activity in a Novel Model, NOD/SCID/MPSVII Mice.

Aldehyde Dehydrogenase-Activity Purifies Multiple Hemangiogenic Lineages That Accelerate Vascularization of Ischemic Tissue through Paracrine Support of Neovessel Formation.

A Prognostic Score for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma: Analysis of 2189 Patients.

Genomic Aberrations in Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma by Absolute Lymphocyte Count: Analysis of 1694 Patients.

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells

Human CD34+Cells Mobilized by AMD3100 Demonstrate Enhanced NOD/SCID Repopulating Function Compared to CD34+ Cells Mobilized by Granulocyte Colony Stimulating Factor.

Comparison of Human Stem Cell Homing after Intravenous or Intra-Femoral Transplantation Using Multimodal In Vivo Imaging of Repopulating Human CD34+ Cells Labeled with Far-Red Fluorescent-Conjugated Nanoparticles.

Bone Marrow-Derived Aldehyde Dehdrogenase Expressing Cells Possess Endothelial Progenitor Function in Addition to Hematopoietic Repopulating Ability and Aid in Blood Flow Recovery after Acute Ischemic Injury.

In Vivo Imaging and Tracking of Defined, Repopulating Human Stem Cell Subsets Using Fluorescence Conjugated Nanoparticles in a Clinically Applicable Ex Vivo Protocol.

Transplanted Human Aldehyde Dehydrogenase Expressing Stem Cells Circulate and Engraft Nonhematopoietic Tissues.

A Pilot Study Evaluating the Safety and Efficacy of AMD3100 for the Mobilization and Transplantation of HLA-Matched Sibling Donor Hematopoietic Stem Cells in Patients with Advanced Hematological Malignancies.

Transplantation of Human Aldehyde Dehydrogenase Expressing Cells Leads to Widespread Tissue Distribution of Donor Cells in the Novel NOD/SCID/MPSVII Xenotransplantation Model.

Isolation of Human CD34 - Cells with High Aldehyde Dehydrogenase Activity Reveals a Novel Population with Hematopoietic Repopulating Potential.

CD133-Expressing Cells with High Aldehyde Dehydrogenase Activity Represent a Primitive Human Hematopoietic Stem Cell Population with Enhanced Repopulating Potential.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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