Abstract
The CD52 and CD20 antigens are ubiquitously expressed on CLL B cells and are important therapeutic targets for the monoclonal antibodies alemtuzumab and rituximab, respectively. Circulating soluble CD52 (sCD52) and CD20 (sCD20) have been shown to have prognostic value in CLL, non-Hodgkin’s lymphoma and Hodgkin’s disease (
Blood
101
:2507
, 2003
Br J Haem
123
:850
, 2003
JCO
23
:4079
, 2005
Disclosure: No relevant conflicts of interest to declare.
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2006, The American Society of Hematology
2006
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