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Journal Articles

Safety and efficacy of glofitamab for relapsed/refractory large B-cell lymphoma in a multinational real-world study

Open Access
Clinical Trials & Observations
Evgenii Shumilov, Rebecca Wurm-Kuczera, Andrea Kerkhoff, Meng Wang, Thomas Melchardt, Udo Holtick, Ulrike Bacher, Philipp Staber, Paolo Mazzeo, Corinna Leng, David Böckle, Alexander Hölscher, Joseph Kauer, Natalia Rotter, Vladan Vucinic, Jakob Rudzki, David Nachbaur, Veit Bücklein, Ulf Schnetzke, Isabelle Krämer, Kai Wille, Alexander Hasse, Bastian von Tresckow, Mathias Hänel, Christian Koenecke, Giuliano Filippini Velazquez, Andreas Viardot, Christoph Schmid, Lorenz Thurner, Dominik Wolf, Marion Subklewe, Martin Dreyling, Peter Dreger, Sascha Dietrich, Ulrich Keller, Ulrich Jäger, Richard Greil, Thomas Pabst, Georg Lenz, Björn Chapuy
Journal: Blood Advances
Blood Adv (2025) 9 (15): 3865–3877.
https://doi.org/10.1182/bloodadvances.2024014903
Published: 2025
Includes: Supplemental data
Journal Articles

Fatal recurrence of IEC-HS after autologous stem cell boost in patients receiving BCMA-CAR T-cell therapy

Open Access
Snegha Ananth, Nancy Eunice Torres, Bita Sahaf, Lekha Mikkilineni, Sebastian Fernandez-Pol, Darren Salmi, Robert Negrin, Parveen Shiraz, Melody Smith, Sushma Bharadwaj, Wen-Kai Weng, Vanessa E. Kennedy, Saurabh Dahiya, Lori Muffly, David Miklos, Matthew J. Frank, Hitomi Hosoya, Surbhi Sidana
Journal: Blood Advances
Blood Adv (2025) 9 (15): 3832–3836.
https://doi.org/10.1182/bloodadvances.2025016346
Published: 2025
Includes: Supplemental data
Journal Articles

Outcomes in frail patients receiving BCMA-directed bispecific antibodies for relapsed/refractory multiple myeloma

Open Access
Benjamin Adegbite, Carlyn Rose Tan, Tala Shekarkhand, Ross S. Firestone, Eric M. Jurgens, Kevin Miller, Alexander M. Lesokhin, Gunjan L. Shah, Neha Korde, Sridevi Rajeeve, Heather J. Landau, Michael Scordo, Hani Hassoun, Kylee H. Maclachlan, Urvi A. Shah, Malin Hultcrantz, Issam S. Hamadeh, Andriy Derkach, David Nemirovsky, Sergio A. Giralt, Sham Mailankody, Saad Z. Usmani, Hamza Hashmi
Journal: Blood Advances
Blood Adv (2025) 9 (15): 4016–4022.
https://doi.org/10.1182/bloodadvances.2025015973
Published: 2025
Journal Articles

Patient anti-FVIII drug antibodies bind preferentially to a subset of FVIII covalent states

Open Access
Diego Butera, Aster E. Pijning, Nathan G. Avery, Carmen H. Coxon, Clive Metcalfe, Angelina Mimoun, Sébastien Lacroix-Desmazes, Paul Clint Spiegel, Jr., Philip J. Hogg
Journal: Blood Advances
Blood Adv (2025) 9 (15): 3706–3715.
https://doi.org/10.1182/bloodadvances.2025016474
Published: 2025
Includes: Supplemental data
Journal Articles

T-cell dysfunction during blinatumomab therapy in pediatric acute lymphoblastic leukemia

Open Access
Julie Ma, Annie Luong, Andrew Doan, Tsen Yin Lin, Lingyun Ji, Cassandra P. Wang, Seon-Jae Yoon, Teresa Rushing, Anh Duong, Miguel Villa, Chintan Parekh
Journal: Blood Advances
Blood Adv (2025) 9 (15): 3689–3693.
https://doi.org/10.1182/bloodadvances.2025015894
Published: 2025
Includes: Supplemental data
Journal Articles

Single-cell sequencing on PBMCs from patients with HA and HB with inhibitors reveals different immune responses to FVIII and FIX

Open Access
Enhao Li, Zekun Li, Jinzeng Wang, Haoyang Wu, Yilun Xue, Can Lou, Zhenping Chen, Feng Liu, Wenman Wu, Qiulan Ding, Runhui Wu, Xuefeng Wang, Jing Dai
Journal: Blood Advances
Blood Adv (2025) 9 (15): 3967–3978.
https://doi.org/10.1182/bloodadvances.2025015799
Published: 2025
Includes: Supplemental data
Journal Articles

Real-World Outcomes of Infections Following Tisagenlecleucel in Patients with B-Cell ALL: A CIBMTR Analysis

Open Access
Hemalatha G. Rangarajan, Prakash Satwani, Megan M. Herr, Min Chen, Michael J. Martens, Kitsada Wudhikarn, Samuel John, Vanessa A. Fabrizio, Emily M. Hsieh, Amar H. Kelkar, Erin Doherty, David I. Marks, Olle Ringden, Brian D. Friend, Matthew S. Kelly, Nosha Farhadfar, Timothy Prestidge, Nasheed M. Hossain, Hongtao Liu, Shahrukh Hashmi, Dipenkumar Modi, Lena E. Winestone, Zeinab El Boghdadly, Hemant S. Murthy, Miguel-Angel Perales, Roy F. Chemaly, Christopher E. Dandoy, Joshua A. Hill, Anna R. Huppler, Marcie Riches, Jeff J. Auletta
Journal: Blood Advances
Blood Adv bloodadvances.2025016149.
https://doi.org/10.1182/bloodadvances.2025016149
Published: 2025
Includes: Supplemental data
Journal Articles

Targeting S100A9-mediated inflammation: A novel therapeutic approach for CLL

Open Access
Angimar Uriepero-Palma, Maria Elena Marquez, Dr., Eugenia Payque, Melanie Mediavilla-Varela, Wael Gamal, Kamira Maharaj, John J Powers, Erika Adriana Eksioglu, Julio C. Chavez, Sandra Sernbo, Florencia Palacios, Juliana Querol Rivas, Claudia Ortega, Rita Uria, Gimena dos Santos, Carolina Oliver, Ana Ines Landoni, Dra, Eva Sahakian, Pablo Oppezzo, Javier Pinilla-Ibarz
Journal: Blood Advances
Blood Adv bloodadvances.2025016061.
https://doi.org/10.1182/bloodadvances.2025016061
Published: 2025
Includes: Supplemental data
Journal Articles

HLA-E[pHLA-G] Complex Specific Monoclonal Antibody Enhancing NK Activity in Multiple Myeloma

Open Access
Muhammad Abu Ahmad, Olga Radinsky, Bar Kaufman, Kamran Waidha, Eman Gharra, Sharon Dim, Dinesh Babu Manikandan, Noa Ofir, Dirk Jäger, Marten Meyer, Moshe Elkabets, Kerry S. Campbell, Miri Zektser, Roi Gazit, Ory Rouvio, Frank Momburg, Angel Porgador
Journal: Blood Advances
Blood Adv bloodadvances.2025016276.
https://doi.org/10.1182/bloodadvances.2025016276
Published: 2025
Includes: Supplemental data
Journal Articles

Characterization and prediction of hematotoxicity in pediatric patients receiving tisagenlecuecel

Open Access
Swati Naik, Subodh Selukar, Aimee C Talleur, Samira Deshpande, Gabriela Llaurador Caraballo, Vanessa A. Fabrizio, Rayne H Rouce, Xiaopei Lily Zeng, Anant Vatsayan, Jenna Rossoff, Holly L Pacenta, Samuel John, Christine L. Phillips, Julie-An M. Talano, Amy Moskop, Michael R Verneris, Gary Douglas Myers, Erin M. Hall, Nicole A. Karras, Challice L Bonifant, Muna Qayed, Emily Bakinowski, Amy Keating, Susanne H.C. Baumeister, Emily Tomilson, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Vasant Chinnabhandar, Heather E Stefanski, Emily Egeler, Kevin J. Curran, Theodore W. Laetsch, Crystal L. Mackall, Snehit Prabhu, Khanh Nguyen, Christina Baggott, Liora M. Schultz, Kevin O. McNerney
Journal: Blood Advances
Blood Adv bloodadvances.2025016824.
https://doi.org/10.1182/bloodadvances.2025016824
Published: 2025
Includes: Supplemental data
Journal Articles

Interferon gamma rebalances immunopathological signatures in Chronic Granulomatous Disease through metabolic rewiring

Open Access
Mariolina Bruno, Charlotte Kröger, Anaísa V. Ferreira, Bowen Zhang, Rutger J. Röring, Ruiqi Liu, Caspar I. van der Made, Norman van Rhijn, Lazslo Groh, Viola Klück, Nico A.F. Janssen, Wenchao Li, Diletta Rosati, Ahmed Alaswad, Helin Tercan, Jorge Saiz, Carolina Gonzalez-Riano, Martina van Uelft, Orsi Gaal, Sophie Müller, Humberto J. Ferreira, Stefanie Warnat-Herresthal, Matthias Becker, Lisa Holsten, Michael Kraut, Jonas Schulte-Schrepping, Lorenzo Bonaguro, Kristian Händler, Cristina Cunha, Manfred Schmolz, Joachim L Schultze, Leo Joosten, Coral Barbas, Mihai G Netea, Yang Li, Anna C. Aschenbrenner, Agostinho Carvalho, Frank L. van de Veerdonk
Journal: Blood Advances
Blood Adv bloodadvances.2025016213.
https://doi.org/10.1182/bloodadvances.2025016213
Published: 2025
Includes: Supplemental data
Journal Articles

Population-based validation of the CAR-HEMATOTOX for hematotoxicity, infections and survival after CART in R/R LBCL

Open Access
Janneke W de Boer, Kylie Keijzer, Suzanne van Dorp, Pim G.N.J. Mutsaers, Anne GH Niezink, Jaap A van Doesum, Yasmina IM Serroukh, Louise W Muntendam, Astrid E Pulles, Esther J Kret, Aniko Sijs-Szabo, Jesse Oomen, Astrid MP Demandt, Wendy BC Stevens, Maria T Kuipers, Elise RA Pennings, Anne Mea Spanjaart, Marie José Kersten, Margot Jak, Lisanne Vania van Dijk, Marjolein WM van der Poel, Joost SP Vermaat, Tom van van Meerten
Journal: Blood Advances
Blood Adv bloodadvances.2025016689.
https://doi.org/10.1182/bloodadvances.2025016689
Published: 2025
Includes: Supplemental data
Journal Articles

Intrathecal chemotherapy for ciltacabtagene autoleucel–associated movement and neurocognitive toxicity

Open Access
Kaitlin Kelly, Jennifer H. Cooperrider, Michael R. Bishop, Satyajit Kosuri, Andrzej Jakubowiak, Benjamin A. Derman
Journal: Blood Advances
Blood Adv (2025) 9 (14): 3613–3616.
https://doi.org/10.1182/bloodadvances.2024015721
Published: 2025
Includes: Supplemental data
Journal Articles

Transplant outcomes using older matched sibling donors compared with young alternative donors: a CIBMTR analysis

Open Access
Karthik Nath, Mei-Jie Zhang, Matthew Bye, Muhammad Bilal Abid, Cara Benjamin, Brian Betts, Neel S. Bhatt, Esteban Arrieta Bolaños, Yung-Tsi Bolon, Shahinaz M. Gadalla, Michael R. Grunwald, Maxwell M. Krem, Stephanie J. Lee, Steven G. E. Marsh, Rodrigo Martino, Parinda A. Mehta, Filippo Milano, Timothy Prestidge, Jennifer N. Saultz, Bronwen E. Shaw, Stephen R. Spellman, Hannah Choe, Brian C. Shaffer
Journal: Blood Advances
Blood Adv (2025) 9 (14): 3469–3478.
https://doi.org/10.1182/bloodadvances.2024014858
Published: 2025
Includes: Supplemental data
Journal Articles

Antibiotic use: impact on the microbiome and cellular therapy outcomes

Open Access
Alicia Darwin, Jiayi Xie, Melody Smith
Journal: Blood Advances
Blood Adv (2025) 9 (13): 3356–3367.
https://doi.org/10.1182/bloodadvances.2024013809
Published: 2025
Journal Articles

Nivolumab plus relatlimab for patients with relapsed or progressed B-cell malignancies in RELATIVITY-022

Open Access
Clinical Trials & Observations
Ajay K. Gopal, Philippe Armand, Sattva S. Neelapu, Nancy L. Bartlett, Stephen E. Spurgeon, John Kuruvilla, Kerry J. Savage, John P. Leonard, Arnold B. Gelb, Nasir Ahmed, Shiqi Dong, Sai Praneeth Bathena, Rasika Suryawanshi, Jenny Qun Wu, Sheen Wang, Douglas E. Gladstone
Journal: Blood Advances
Blood Adv (2025) 9 (13): 3383–3394.
https://doi.org/10.1182/bloodadvances.2024015086
Published: 2025
Includes: Supplemental data
Journal Articles

Throwing the microbiome out with the bathwater

Open Access
Marcus Geer, Mary Riwes
Journal: Blood Advances
Blood Adv (2025) 9 (13): 3368–3369.
https://doi.org/10.1182/bloodadvances.2025016205
Published: 2025
Journal Articles

Mature megakaryocytes acquire immune characteristics in a mouse model of aplastic anemia

Open Access
Ashvind Prabahran, Liangliang Wu, Ash Lee Manley, Zhijie Wu, Shouguo Gao, Hiroki Mizumaki, Valentina Baena, Zulfeqhar Syed, Christian A. Combs, Jichun Chen, Xingmin Feng, Neal S. Young
Journal: Blood Advances
Blood Adv (2025) 9 (13): 3315–3330.
https://doi.org/10.1182/bloodadvances.2024015621
Published: 2025
Includes: Supplemental data
Journal Articles

Expression and treatment of ROR1 + cells with bispecific T-cell engagers in pediatric acute lymphoblastic leukemia

Open Access
Paraskevi Diamanti, Bethan K. Bailey, Obinna E. Iheanacho, John P. Moppett, Amit C. Nathwani, Allison Blair
Journal: Blood Advances
Blood Adv (2025) 9 (13): 3190–3201.
https://doi.org/10.1182/bloodadvances.2024013814
Published: 2025
Includes: Supplemental data
Journal Articles

Invasive fungal disease is rare in patients with relapsed/refractory multiple myeloma treated with BCMA CAR T-cell therapy

Open Access
Jessica S. Little, Angelica Medina Pena, E. Bridget Kim, Andrew J. Yee, Omar Nadeem, Shonali Midha, Adam S. Sperling, Nikhil C. Munshi, Noopur S. Raje, Matthew J. Frigault, Diana D. Cirstea, Sarah P Hammond
Journal: Blood Advances
Blood Adv bloodadvances.2025016748.
https://doi.org/10.1182/bloodadvances.2025016748
Published: 2025
Includes: Supplemental data