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Journal Articles

Fatal late-onset CAR T-cell–mediated encephalitis after axicabtagene-ciloleucel in a patient with large B-cell lymphoma

Clinical Trials & Observations
Susanne Jung, Jochen Greiner, Stephanie von Harsdorf, Pavle Popovic, Roland Moll, Jens Schittenhelm, Kosmas Kandilaris, Volker Daniel, Alexander Kunz, Michael Schmitt, Peter Dreger
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3789–3793.
https://doi.org/10.1182/bloodadvances.2021004889
Published: 2021
Includes: Supplemental data
Journal Articles

DKK1 activates noncanonical NF-κB signaling via IL-6–induced CKAP4 receptor in multiple myeloma

Xin Li, Jingjing Wang, Shuai Zhu, Jinxin Zheng, Ying Xie, Hongmei Jiang, Jing Guo, Yixuan Wang, Ziyi Peng, Mengqi Wang, Jingya Wang, Sheng Wang, Yuping Zhong, Zhiqiang Liu
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3656–3667.
https://doi.org/10.1182/bloodadvances.2021004315
Published: 2021
Includes: Supplemental data
Journal Articles

IFN-γ signature in the plasma proteome distinguishes pediatric hemophagocytic lymphohistiocytosis from sepsis and SIRS

Howard Lin, Brooks P. Scull, Baruch R. Goldberg, Harshal A. Abhyankar, Olive E. Eckstein, Daniel J. Zinn, Joseph Lubega, Jennifer Agrusa, Nader El Mallawaney, Nitya Gulati, Lisa Forbes, Ivan Chinn, Rikhia Chakraborty, Jessica Velasquez, Jordana Goldman, Dalia Bashir, Fong Lam, Eyal Muscal, Michael. M. Henry, Jay N. Greenberg, Stephan Ladisch, Michelle L. Hermiston, Lauren K. Meyer, Michael Jeng, Ahmed Naqvi, Kenneth McClain, Trung Nguyen, Hector Wong, Tsz-Kwong Man, Michael B. Jordan, Carl E. Allen
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3457–3467.
https://doi.org/10.1182/bloodadvances.2021004287
Published: 2021
Includes: Supplemental data
Journal Articles

Discovery and validation of a novel subgroup and therapeutic target in idiopathic multicentric Castleman disease

Sheila K. Pierson, Sushila Shenoy, Ana B. Oromendia, Alexander M. Gorzewski, Ruth-Anne Langan Pai, Christopher Shield Nabel, Jason R. Ruth, Sophia A. T. Parente, Daniel J. Arenas, Mary Guilfoyle, Manjula Reddy, Michael Weinblatt, Nancy Shadick, Mark Bower, Alessia Dalla Pria, Yasufumi Masaki, Laura Katz, Jason Mezey, Philip Beineke, David Lee, Craig Tendler, Taku Kambayashi, Alexander Fosså, Frits van Rhee, David C. Fajgenbaum
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3445–3456.
https://doi.org/10.1182/bloodadvances.2020004016
Published: 2021
Includes: Supplemental data
Journal Articles

Activated IL-6 signaling contributes to the pathogenesis of, and is a novel therapeutic target for, CALR -mutated MPNs

Manjola Balliu, Laura Calabresi, Niccolò Bartalucci, Simone Romagnoli, Laura Maggi, Rossella Manfredini, Matteo Lulli, Paola Guglielmelli, Alessandro Maria Vannucchi
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2184–2195.
https://doi.org/10.1182/bloodadvances.2020003291
Published: 2021
Includes: Supplemental data
Journal Articles

Revisiting IL-6 expression in the tumor microenvironment of classical Hodgkin lymphoma

Alex Reza Gholiha, Peter Hollander, Ingrid Glimelius, Gustaf Hedstrom, Daniel Molin, Henrik Hjalgrim, Karin E. Smedby, Jamileh Hashemi, Rose-Marie Amini, Gunilla Enblad
Journal: Blood Advances
Blood Adv (2021) 5 (6): 1671–1681.
https://doi.org/10.1182/bloodadvances.2020003664
Published: 2021
Includes: Supplemental data
Journal Articles

Chimeric antigen receptor–T cells with cytokine neutralizing capacity

Adrian H. J. Tan, Natasha Vinanica, Dario Campana
Journal: Blood Advances
Blood Adv (2020) 4 (7): 1419–1431.
https://doi.org/10.1182/bloodadvances.2019001287
Published: 2020
Includes: Supplemental data
Journal Articles

Proteomic profiling of HTLV-1 carriers and ATL patients reveals sTNFR2 as a novel diagnostic biomarker for acute ATL

Carmina Louise Hugo Guerrero, Yoshiko Yamashita, Megumi Miyara, Naoki Imaizumi, Megumi Kato, Shugo Sakihama, Masaki Hayashi, Takashi Miyagi, Kaori Karimata, Junnosuke Uchihara, Kazuiku Ohshiro, Junpei Todoroki, Sawako Nakachi, Satoko Morishima, Kennosuke Karube, Yuetsu Tanaka, Hiroaki Masuzaki, Takuya Fukushima
Journal: Blood Advances
Blood Adv (2020) 4 (6): 1062–1071.
https://doi.org/10.1182/bloodadvances.2019001429
Published: 2020
Includes: Supplemental data
Journal Articles

First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia

Clinical Trials & Observations
Sarah Cooley, Fiona He, Veronika Bachanova, Gregory M. Vercellotti, Todd E. DeFor, Julie M. Curtsinger, Paul Robertson, Bartosz Grzywacz, Kevin C. Conlon, Thomas A. Waldmann, David H. McKenna, Bruce R. Blazar, Daniel J. Weisdorf, Jeffrey S. Miller
Journal: Blood Advances
Blood Adv (2019) 3 (13): 1970–1980.
https://doi.org/10.1182/bloodadvances.2018028332
Published: 2019
Includes: Supplemental data
Journal Articles

Morphine promotes neovascularizing retinopathy in sickle transgeneic mice

Kalpna Gupta, Chunsheng Chen, Gerard A. Lutty, Robert P. Hebbel
Journal: Blood Advances
Blood Adv (2019) 3 (7): 1073–1083.
https://doi.org/10.1182/bloodadvances.2018026898
Published: 2019
Includes: Supplemental data
Journal Articles

Soluble PD-1 ligands regulate T-cell function in Waldenstrom macroglobulinemia

Shahrzad Jalali, Tammy Price-Troska, Jonas Paludo, Jose Villasboas, Hyo-Jin Kim, Zhi-Zhang Yang, Anne J. Novak, Stephen M. Ansell
Journal: Blood Advances
Blood Adv (2018) 2 (15): 1985–1997.
https://doi.org/10.1182/bloodadvances.2018021113
Published: 2018
Journal Articles

TLR2 agonism reverses chemotherapy-induced neutropenia in Macaca fascicularis

Nicholas J. Laping, Michael P. DeMartino, Joshua E. Cottom, Jeffrey M. Axten, John G. Emery, Jeffrey H. Guss, Miriam Burman, James J. Foley, Mui Cheung, Allen Oliff, Sanjay Kumar
Journal: Blood Advances
Blood Adv (2017) 1 (26): 2553–2562.
https://doi.org/10.1182/bloodadvances.2017010611
Published: 2017
Journal Articles

Interleukin-6 levels predict event-free survival in pediatric AML and suggest a mechanism of chemotherapy resistance

Clinical Trials & Observations
Alexandra M. Stevens, Jennifer M. Miller, Jaime O. Munoz, Amos S. Gaikwad, Michele S. Redell
Journal: Blood Advances
Blood Adv (2017) 1 (18): 1387–1397.
https://doi.org/10.1182/bloodadvances.2017007856
Published: 2017
Includes: Supplemental data
Journal Articles

WNT ligands contribute to the immune response during septic shock and amplify endotoxemia-driven inflammation in mice

Marcela Gatica-Andrades, Dimitrios Vagenas, Jessica Kling, Tam T. K. Nguyen, Helen Benham, Ranjeny Thomas, Heinrich Körner, Bala Venkatesh, Jeremy Cohen, Antje Blumenthal
Journal: Blood Advances
Blood Adv (2017) 1 (16): 1274–1286.
https://doi.org/10.1182/bloodadvances.2017006163
Published: 2017
Includes: Supplemental data
Journal Articles

Substrate-bound CCL21 and ICAM1 combined with soluble IL-6 collectively augment the expansion of antigen-specific murine CD4 + T cells

Shimrit Adutler-Lieber, Irina Zaretsky, Helena Sabany, Elena Kartvelishvily, Ofra Golani, Benjamin Geiger, Nir Friedman
Journal: Blood Advances
Blood Adv (2017) 1 (15): 1016–1030.
https://doi.org/10.1182/bloodadvances.2016001545
Published: 2017
Includes: Multimedia, Supplemental data
Journal Articles

Proliferation through activation: hemophagocytic lymphohistiocytosis in hematologic malignancy

Eric J. Vick, Kruti Patel, Philippe Prouet, Mike G. Martin
Journal: Blood Advances
Blood Adv (2017) 1 (12): 779–791.
https://doi.org/10.1182/bloodadvances.2017005561
Published: 2017