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hemophagocytic lymphohistiocytosis
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Journal Articles

IFN-γ signature in the plasma proteome distinguishes pediatric hemophagocytic lymphohistiocytosis from sepsis and SIRS

Howard Lin, Brooks P. Scull, Baruch R. Goldberg, Harshal A. Abhyankar, Olive E. Eckstein, Daniel J. Zinn, Joseph Lubega, Jennifer Agrusa, Nader El Mallawaney, Nitya Gulati, Lisa Forbes, Ivan Chinn, Rikhia Chakraborty, Jessica Velasquez, Jordana Goldman, Dalia Bashir, Fong Lam, Eyal Muscal, Michael. M. Henry, Jay N. Greenberg, Stephan Ladisch, Michelle L. Hermiston, Lauren K. Meyer, Michael Jeng, Ahmed Naqvi, Kenneth McClain, Trung Nguyen, Hector Wong, Tsz-Kwong Man, Michael B. Jordan, Carl E. Allen
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3457–3467.
https://doi.org/10.1182/bloodadvances.2021004287
Published: 2021
Includes: Supplemental data
Journal Articles

Felber M, Steward CG, Kentouche K, et al. Targeted busulfan-based reduced-intensity conditioning and HLA-matched HSCT cure hemophagocytic lymphohistiocytosis. Blood Adv. 2020;4(9):1998-2010.

Journal: Blood Advances
Blood Adv (2020) 4 (16): 3926.
https://doi.org/10.1182/bloodadvances.2020003085
Published: 2020
Journal Articles

Stem cell transplantation for children with hemophagocytic lymphohistiocytosis: results from the HLH-2004 study

Clinical Trials & Observations
Elisabet Bergsten, AnnaCarin Horne, Ida Hed Myrberg, Maurizio Aricó, Itziar Astigarraga, Eiichi Ishii, Gritta Janka, Stephan Ladisch, Kai Lehmberg, Kenneth L. McClain, Milen Minkov, Vasanta Nanduri, Diego A. Rosso, Elena Sieni, Jacek Winiarski, Jan-Inge Henter
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3754–3766.
https://doi.org/10.1182/bloodadvances.2020002101
Published: 2020
Includes: Supplemental data
Journal Articles

Line-selective macrophage activation with an anti-CD40 antibody drives a hemophagocytic syndrome in mice

Giada Ingoglia, Ayla Yalamanoglu, Marc Pfefferlé, Irina L. Dubach, Christian A. Schaer, Kristyna Valkova, Kerstin Hansen, Nadja Schulthess, Rok Humar, Dominik J. Schaer, Florence Vallelian
Journal: Blood Advances
Blood Adv (2020) 4 (12): 2751–2761.
https://doi.org/10.1182/bloodadvances.2020001624
Published: 2020
Includes: Supplemental data
Journal Articles

Frequency and spectrum of disease-causing variants in 1892 patients with suspected genetic HLH disorders

Clinical Trials & Observations
Vanessa Gadoury-Levesque, Lei Dong, Rui Su, Jianjun Chen, Kejian Zhang, Kimberly A. Risma, Rebecca A. Marsh, Miao Sun
Journal: Blood Advances
Blood Adv (2020) 4 (12): 2578–2594.
https://doi.org/10.1182/bloodadvances.2020001605
Published: 2020
Includes: Supplemental data
Journal Articles

Targeted busulfan-based reduced-intensity conditioning and HLA-matched HSCT cure hemophagocytic lymphohistiocytosis

Clinical Trials & Observations
Matthias Felber, Colin G. Steward, Karim Kentouche, Anders Fasth, Robert F. Wynn, Ulrike Zeilhofer, Veronika Haunerdinger, Benjamin Volkmer, Seraina Prader, Bernd Gruhn, Stephan Ehl, Kai Lehmberg, Daniel Müller, Andrew R. Gennery, Michael H. Albert, Fabian Hauck, Kanchan Rao, Paul Veys, Moustapha Hassan, Arjan C. Lankester, Jana Pachlopnik Schmid, Mathias M. Hauri-Hohl, Tayfun Güngör
Journal: Blood Advances
Blood Adv (2020) 4 (9): 1998–2010.
https://doi.org/10.1182/bloodadvances.2020001748
Published: 2020
Includes: Supplemental data
Journal Articles

Efficacy of ruxolitinib in subcutaneous panniculitis-like T-cell lymphoma and hemophagocytic lymphohistiocytosis

Clinical Trials & Observations
Romain Lévy, Mathieu Fusaro, Frédéric Guerin, Ahmed Chetouani, Despina Moshous, Alain Fischer, Geneviève de Saint Basile, Fernando E. Sepulveda, Bénédicte Neven
Journal: Blood Advances
Blood Adv (2020) 4 (7): 1383–1387.
https://doi.org/10.1182/bloodadvances.2020001497
Published: 2020
Journal Articles

Identification of germline variants in adults with hemophagocytic lymphohistiocytosis

Peter G. Miller, Abhishek Niroula, John J. Ceremsak, Christopher J. Gibson, Martin S. Taylor, Sebastian Birndt, Florian Perner, Jon Arnason, Adam S. Sperling, Mridul Agrawal, Alison M. Schram, Sarah Nikiforow, German Pihan, Robert P. Hasserjian, Jon C. Aster, Paul La Rosée, Elizabeth A. Morgan, Nancy Berliner, Benjamin L. Ebert
Journal: Blood Advances
Blood Adv (2020) 4 (5): 925–929.
https://doi.org/10.1182/bloodadvances.2019001272
Published: 2020
Includes: Supplemental data
Journal Articles

Resolution of secondary hemophagocytic lymphohistiocytosis after treatment with the JAK1/2 inhibitor ruxolitinib

Clinical Trials & Observations
Scott R. Goldsmith, Sana Saif Ur Rehman, Cara L. Shirai, Kiran Vij, John F. DiPersio
Journal: Blood Advances
Blood Adv (2019) 3 (23): 4131–4135.
https://doi.org/10.1182/bloodadvances.2019000898
Published: 2019
Journal Articles

Central nervous system–restricted familial hemophagocytic lymphohistiocytosis responds to hematopoietic cell transplantation

Clinical Trials & Observations
Hojun Li, Leslie A. Benson, Lauren A. Henderson, Isaac H. Solomon, Alyssa L. Kennedy, Ariane Soldatos, Bibiana Bielekova, Jennifer Murphy, Kimberly J. Davies, Leslie E. Lehmann, Michelle A. Lee, Sanda Alexandrescu, Barbara A. Degar, Mark P. Gorman, Christine N. Duncan
Journal: Blood Advances
Blood Adv (2019) 3 (4): 503–507.
https://doi.org/10.1182/bloodadvances.2018027417
Published: 2019
Includes: Supplemental data
Journal Articles

Treatment of refractory hemophagocytic lymphohistiocytosis with emapalumab despite severe concurrent infections

Clinical Trials & Observations
Dana T. Lounder, Qiong Bin, Cristina de Min, Michael B. Jordan
Journal: Blood Advances
Blood Adv (2019) 3 (1): 47–50.
https://doi.org/10.1182/bloodadvances.2018025858
Published: 2019
Journal Articles

Soluble interleukin-2 receptor is a sensitive diagnostic test in adult HLH

Clinical Trials & Observations
Anna Hayden, Molly Lin, Sujin Park, Morris Pudek, Marion Schneider, Michael B. Jordan, Andre Mattman, Luke Y. C. Chen
Journal: Blood Advances
Blood Adv (2017) 1 (26): 2529–2534.
https://doi.org/10.1182/bloodadvances.2017012310
Published: 2017
Includes: Supplemental data
Journal Articles

Ruxolitinib for treatment of refractory hemophagocytic lymphohistiocytosis

Clinical Trials & Observations
Larisa Broglie, Lauren Pommert, Sridhar Rao, Monica Thakar, Rachel Phelan, David Margolis, Julie Talano
Journal: Blood Advances
Blood Adv (2017) 1 (19): 1533–1536.
https://doi.org/10.1182/bloodadvances.2017007526
Published: 2017
Journal Articles

Proliferation through activation: hemophagocytic lymphohistiocytosis in hematologic malignancy

Eric J. Vick, Kruti Patel, Philippe Prouet, Mike G. Martin
Journal: Blood Advances
Blood Adv (2017) 1 (12): 779–791.
https://doi.org/10.1182/bloodadvances.2017005561
Published: 2017
Journal Articles

Genetic analysis of B-cell lymphomas associated with hemophagocytic lymphohistiocytosis

Kruti Patel, Sophia S. Lee, Poojitha Valasareddy, Namratha R. Vontela, Philippe Prouet, Mike G. Martin
Journal: Blood Advances
Blood Adv (2016) 1 (3): 205–207.
https://doi.org/10.1182/bloodadvances.2016002006
Published: 2016