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Taco W. Kuijpers
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Journal Articles

Platelet proteomic profiling in sitosterolemia suggests thrombocytopenia is driven by lipid disorder and not platelet aberrations

Jessica Del Castillo, Anton T. J. Tool, Karin van Leeuwen, Floris P. J. van Alphen, Marion M. Brands, Monique H. Suijker, Alexander B. Meijer, Arie J. Hoogendijk, Taco W. Kuijpers
Journal: Blood Advances
Blood Adv (2024) 8 (10): 2466–2477.
https://doi.org/10.1182/bloodadvances.2023012018
Published: 2024
Includes: Supplemental data
Journal Articles

Lack of eosinophil extracellular trap formation due to failure of plasma membrane breakdown in the absence of elastase

Evelien G. G. Sprenkeler, Ines Goetschalckx, Sara Fernández Hermira, Anton T. J. Tool, Mark Hoogenboezem, Robin van Bruggen, Taco W. Kuijpers
Journal: Blood Advances
Blood Adv (2023) 7 (19): 5868–5876.
https://doi.org/10.1182/bloodadvances.2022009432
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

Megalobastic anemia, infantile leukemia, and immunodeficiency caused by a novel homozygous mutation in the DHFR gene

Taco W. Kuijpers, Andrica C. H. de Vries, Ester M. van Leeuwen, A.(Ton) A. M. Ermens, Saskia de Pont, Desirée E. C. Smith, Mirjam M. C. Wamelink, Arjen R. Mensenkamp, Marcel R. Nelen, Hana Lango Allen, Steven T. Pals, Berna H. B. Beverloo, Hidde H. Huidekoper, Anja Wagner
Journal: Blood Advances
Blood Adv (2022) 6 (22): 5829–5834.
https://doi.org/10.1182/bloodadvances.2022007233
Published: 2022
Journal Articles

Malaria-associated adhesion molecule activation facilitates the destruction of uninfected red blood cells

Jill J. Dalimot, Thomas R. L. Klei, Boukje M. Beuger, Zeynep Dikmen, Suzan A. M. Bouwman, Ghyslain Mombo-Ngoma, Rella Zoleko-Manego, Wilfrid F. Ndzebe-Ndoumba, Stéphane Egée, Taco W. Kuijpers, Martin P. Grobusch, Robin van Bruggen
Journal: Blood Advances
Blood Adv (2022) 6 (21): 5798–5810.
https://doi.org/10.1182/bloodadvances.2021006171
Published: 2022
Includes: Multimedia, Supplemental data
Journal Articles

Treatment of an HLH-mimic disease based on HAVCR2 variants with absent TIM-3 expression

Clinical Trials & Observations
Samantha A. M. Tromp, Marijn A. Gillissen, Sophie J. Bernelot Moens, Ester M. M. van Leeuwen, Machiel H. Jansen, Lianne Koens, Caroline E. Rutten, Taco W. Kuijpers
Journal: Blood Advances
Blood Adv (2022) 6 (15): 4501–4505.
https://doi.org/10.1182/bloodadvances.2022007450
Published: 2022
Includes: Supplemental data
Journal Articles

Sodium stibogluconate and CD47-SIRPα blockade overcome resistance of anti-CD20–opsonized B cells to neutrophil killing

Dieke J. van Rees, Maximilian Brinkhaus, Bart Klein, Paul Verkuijlen, Anton T.J. Tool, Karin Schornagel, Louise W. Treffers, Michel van Houdt, Arnon P. Kater, Gestur Vidarsson, Andrew R. Gennery, Taco W. Kuijpers, Robin van Bruggen, Hanke L. Matlung, Timo K. van den Berg
Journal: Blood Advances
Blood Adv (2022) 6 (7): 2156–2166.
https://doi.org/10.1182/bloodadvances.2021005367
Published: 2022
Includes: Supplemental data
Journal Articles

Neutrophil specific granule and NETosis defects in gray platelet syndrome

Cathelijn E. M. Aarts, Kate Downes, Arie J. Hoogendijk, Evelien G. G. Sprenkeler, Roel P. Gazendam, Rémi Favier, Marie Favier, Anton T. J. Tool, John L. van Hamme, Myrto A. Kostadima, Kate Waller, Barbara Zieger, Maaike G. J. M. van Bergen, Saskia M. C. Langemeijer, Bert A. van der Reijden, Hans Janssen, Timo K. van den Berg, Robin van Bruggen, Alexander B. Meijer, Willem H. Ouwehand, Taco W. Kuijpers
Journal: Blood Advances
Blood Adv (2021) 5 (2): 549–564.
https://doi.org/10.1182/bloodadvances.2020002442
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

The Gardos effect drives erythrocyte senescence and leads to Lu/BCAM and CD44 adhesion molecule activation

Thomas R. L. Klei, Jill J. Dalimot, Boukje M. Beuger, Martijn Veldthuis, Fatima Ait Ichou, Paul J. J. H. Verkuijlen, Iris M. Seignette, Peter C. Ligthart, Taco W. Kuijpers, Rob van Zwieten, Robin van Bruggen
Journal: Blood Advances
Blood Adv (2020) 4 (24): 6218–6229.
https://doi.org/10.1182/bloodadvances.2020003077
Published: 2020
Journal Articles

Treatment-associated hemolysis in Kawasaki disease: association with blood-group antibody titers in IVIG products

Clinical Trials & Observations
Christine W. Bruggeman, Sietse Q. Nagelkerke, Wendy Lau, Cedric Manlhiot, Masja de Haas, Robin van Bruggen, Brian W. McCrindle, Rae S. M. Yeung, Taco W. Kuijpers
Journal: Blood Advances
Blood Adv (2020) 4 (14): 3416–3426.
https://doi.org/10.1182/bloodadvances.2020002253
Published: 2020
Includes: Supplemental data
Journal Articles

Activated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair

Cathelijn E. M. Aarts, Ida H. Hiemstra, Eelke P. Béguin, Arjan J. Hoogendijk, Souhailla Bouchmal, Michel van Houdt, Anton T. J. Tool, Erik Mul, Machiel H. Jansen, Hans Janssen, Floris P. J. van Alphen, Jan-Paul de Boer, Charlotte L. Zuur, Alexander B. Meijer, Timo K. van den Berg, Taco W. Kuijpers
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3562–3574.
https://doi.org/10.1182/bloodadvances.2019031609
Published: 2019
Includes: Multimedia, Supplemental data
Journal Articles

Transient and chronic childhood immune thrombocytopenia are distinctly affected by Fc-γ receptor polymorphisms

Clinical Trials & Observations
David E. Schmidt, Katja M. J. Heitink-Pollé, Annemieke G. Laarhoven, Marrie C. A. Bruin, Barbera Veldhuisen, Sietse Q. Nagelkerke, Taco W. Kuijpers, Leendert Porcelijn, C. Ellen van der Schoot, Gestur Vidarsson, Masja de Haas
Journal: Blood Advances
Blood Adv (2019) 3 (13): 2003–2012.
https://doi.org/10.1182/bloodadvances.2019000068
Published: 2019
Includes: Supplemental data
Journal Articles

Neutrophils acquire antigen-presenting cell features after phagocytosis of IgG-opsonized erythrocytes

Sanne M. Meinderts, Gabriella Baker, Stan van Wijk, Boukje M. Beuger, Judy Geissler, Machiel H. Jansen, Anno Saris, Anja ten Brinke, Taco W. Kuijpers, Timo K. van den Berg, Robin van Bruggen
Journal: Blood Advances
Blood Adv (2019) 3 (11): 1761–1773.
https://doi.org/10.1182/bloodadvances.2018028753
Published: 2019
Includes: Supplemental data
Journal Articles

Potentiation of complement regulator factor H protects human endothelial cells from complement attack in aHUS sera

Richard B. Pouw, Mieke C. Brouwer, Marlon de Gast, Anna E. van Beek, Lambertus P. van den Heuvel, Christoph Q. Schmidt, Arie van der Ende, Pilar Sánchez-Corral, Taco W. Kuijpers, Diana Wouters
Journal: Blood Advances
Blood Adv (2019) 3 (4): 621–632.
https://doi.org/10.1182/bloodadvances.2018025692
Published: 2019
Includes: Supplemental data
Journal Articles

Differential antibacterial control by neutrophil subsets

Pieter H. C. Leliefeld, Janesh Pillay, Nienke Vrisekoop, Marjolein Heeres, Tamar Tak, Matthijs Kox, Suzan H. M. Rooijakkers, Taco W. Kuijpers, Peter Pickkers, Luke P. H. Leenen, Leo Koenderman
Journal: Blood Advances
Blood Adv (2018) 2 (11): 1344–1355.
https://doi.org/10.1182/bloodadvances.2017015578
Published: 2018
Includes: Multimedia, Supplemental data
Journal Articles

Red pulp macrophages in the human spleen are a distinct cell population with a unique expression of Fc-γ receptors

Sietse Q. Nagelkerke, Christine W. Bruggeman, Joke M. M. den Haan, Erik P. J. Mul, Timo K. van den Berg, Robin van Bruggen, Taco W. Kuijpers
Journal: Blood Advances
Blood Adv (2018) 2 (8): 941–953.
https://doi.org/10.1182/bloodadvances.2017015008
Published: 2018
Includes: Supplemental data
Journal Articles

Human and murine splenic neutrophils are potent phagocytes of IgG-opsonized red blood cells

Sanne M. Meinderts, Per-Arne Oldenborg, Boukje M. Beuger, Thomas R. L. Klei, Johanna Johansson, Taco W. Kuijpers, Takashi Matozaki, Elise J. Huisman, Masja de Haas, Timo K. van den Berg, Robin van Bruggen
Journal: Blood Advances
Blood Adv (2017) 1 (14): 875–886.
https://doi.org/10.1182/bloodadvances.2017004671
Published: 2017
Includes: Supplemental data