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Issue Archive

Volume 2, Issue 8
April 24 2018
Blood Advances Cover Image for Volume 2, Issue 8

Table of Contents

EXCEPTIONAL CASE REPORT

Can somatic GATA2 mutation mimic germ line GATA2 mutation?
Clinical Trials & Observations
Mallika Sekhar,Rachael Pocock,David Lowe,Christopher Mitchell,Teresa Marafioti,Rachel Dickinson,Matthew Collin,Marc Lipman
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STIMULUS REPORT

Ectopic Lck expression in CLL demarcates intratumoral subpopulations with aberrant B-cell receptor signaling
Efthymia Theofani,Spyridon Alexis,Paul Costeas,Christos Andriopoulos,Georgia Feleskoura,Panagiotis Zikos,Anthi Aktypi,Alexandros Spyridonidis,Konstantina Nika
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CLINICAL TRIALS AND OBSERVATIONS

Patterns of care and outcomes in adolescent and young adult acute lymphoblastic leukemia: a population-based study
Clinical Trials & Observations
Lori Muffly,Elysia Alvarez,Daphne Lichtensztajn,Renata Abrahão,Scarlett Lin Gomez,Theresa Keegan
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HEMATOPOIESIS AND STEM CELLS

M1 and M2 macrophages differentially regulate hematopoietic stem cell self-renewal and ex vivo expansion
Yi Luo,Lijian Shao,Jianhui Chang,Wei Feng,Y. Lucy Liu,Michele H. Cottler-Fox,Peter D. Emanuel,Martin Hauer-Jensen,Irwin D. Bernstein,Lingbo Liu,Xing Chen,Jianfeng Zhou,Peter J. Murray,Daohong Zhou
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IMMUNOBIOLOGY AND IMMUNOTHERAPY

Zinc finger–IRF composite elements bound by Ikaros/IRF4 complexes function as gene repression in plasma cell
Kyoko Ochiai,Haruka Kondo,Yasunobu Okamura,Hiroki Shima,Yuko Kurokochi,Kazumi Kimura,Ryo Funayama,Takeshi Nagashima,Keiko Nakayama,Katsuyuki Yui,Kengo Kinoshita,Kazuhiko Igarashi
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LYMPHOID NEOPLASIA

Pilot trial of ibrutinib in patients with relapsed or refractory T-cell lymphoma
Clinical Trials & Observations
Anita Kumar,Santosha Vardhana,Alison J. Moskowitz,Pierluigi Porcu,Ahmet Dogan,Jason A. Dubovsky,Matthew J. Matasar,Zhigang Zhang,Anas Younes,Steven M. Horwitz
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MYELOID NEOPLASIA

A next-generation sequencing–based assay for minimal residual disease assessment in AML patients with FLT3-ITD mutations
Clinical Trials & Observations
Mark J. Levis,Alexander E. Perl,Jessica K. Altman,Christopher D. Gocke,Erkut Bahceci,Jason Hill,Chaofeng Liu,Zhiyi Xie,Andrew R. Carson,Valerie McClain,Timothy T. Stenzel,Jeffrey E. Miller
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MLL leukemia induction by t(9;11) chromosomal translocation in human hematopoietic stem cells using genome editing
Corina Schneidawind,Johan Jeong,Dominik Schneidawind,In-Suk Kim,Jesús Duque-Afonso,Stephen Hon Kit Wong,Masayuki Iwasaki,Erin H. Breese,James L. Zehnder,Matthew Porteus,Michael L. Cleary
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A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells
Yelena Kovtun,Gregory E. Jones,Sharlene Adams,Lauren Harvey,Charlene A. Audette,Alan Wilhelm,Chen Bai,Lingyun Rui,Rassol Laleau,Fenghua Liu,Olga Ab,Yulius Setiady,Nicholas C. Yoder,Victor S. Goldmacher,Ravi V. J. Chari,Jan Pinkas,Thomas Chittenden
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Hypomethylating agents in relapsed and refractory AML: outcomes and their predictors in a large international patient cohort
Clinical Trials & Observations
Maximilian Stahl,Michelle DeVeaux,Pau Montesinos,Raphael Itzykson,Ellen K. Ritchie,Mikkael A. Sekeres,John D. Barnard,Nikolai A. Podoltsev,Andrew M. Brunner,Rami S. Komrokji,Vijaya R. Bhatt,Aref Al-Kali,Thomas Cluzeau,Valeria Santini,Amir T. Fathi,Gail J. Roboz,Pierre Fenaux,Mark R. Litzow,Sarah Perreault,Tae Kon Kim,Thomas Prebet,Norbert Vey,Vivek Verma,Ulrich Germing,Juan Miguel Bergua,Josefina Serrano,Steven D. Gore,Amer M. Zeidan
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PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

Red pulp macrophages in the human spleen are a distinct cell population with a unique expression of Fc-γ receptors
Sietse Q. Nagelkerke,Christine W. Bruggeman,Joke M. M. den Haan,Erik P. J. Mul,Timo K. van den Berg,Robin van Bruggen,Taco W. Kuijpers
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TRANSPLANTATION

Delayed immune reconstitution after allogeneic transplantation increases the risks of mortality and chronic GVHD
Nelli Bejanyan,Claudio G. Brunstein,Qing Cao,Aleksandr Lazaryan,Xianghua Luo,Julie Curtsinger,Rohtesh S. Mehta,Erica Warlick,Sarah A. Cooley,Bruce R. Blazar,Jeffrey S. Miller,Daniel Weisdorf,John E. Wagner,Michael R. Verneris
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Outcomes of Medicare-age eligible NHL patients receiving RIC allogeneic transplantation: a CIBMTR analysis
Clinical Trials & Observations
Nirav N. Shah,Kwang Woo Ahn,Carlos Litovich,Timothy S. Fenske,Sairah Ahmed,Minoo Battiwalla,Nelli Bejanyan,Parastoo B. Dahi,Javier Bolaños-Meade,Andy I. Chen,Stefan O. Ciurea,Veronika Bachanova,Zachariah DeFilipp,Narendranath Epperla,Nosha Farhadfar,Alex F. Herrera,Bradley M. Haverkos,Leona Holmberg,Nasheed M. Hossain,Mohamed A. Kharfan-Dabaja,Vaishalee P. Kenkre,Hillard M. Lazarus,Hemant S. Murthy,Taiga Nishihori,Andrew R. Rezvani,Anita D’Souza,Bipin N. Savani,Matthew L. Ulrickson,Edmund K. Waller,Anna Sureda,Sonali M. Smith,Mehdi Hamadani
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COMMENTARY

Approaching the crisis in medical research funding: an important role for nonprofit organizations and medical societies
Janis L. Abkowitz,Robert Hromas
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All Issues

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