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Issue Archive

Volume 2, Issue 11
June 12 2018
Issue Cover

Table of Contents

EXCEPTIONAL CASE REPORTS

Clinical, molecular, and immunological responses to pembrolizumab treatment of synchronous melanoma and acute myeloid leukemia
Clinical Trials & Observations
Anne Sophie Kubasch,Rebekka Wehner,Serena Bazzurri,Antje Tunger,Sebastian Stasik,Marlene Garzarolli,Jörn Meinel,Gustavo Baretton,Friedegund Meier,Christian Thiede,Marc Schmitz,Uwe Platzbecker
View Articletitled, Clinical, molecular, and immunological responses to pembrolizumab treatment of synchronous melanoma and acute myeloid leukemia
Supplemental data
A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion
Clinical Trials & Observations
Christopher A. Miller,Christopher Tricarico,Zachary L. Skidmore,Geoffrey L. Uy,Yi-Shan Lee,Anjum Hassan,Michelle D. O’Laughlin,Heather Schmidt,Ling Tian,Eric J. Duncavage,Malachi Griffith,Obi L. Griffith,John S. Welch,Lukas D. Wartman
View Articletitled, A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel <em>RARG</em>-<em>CPSF6</em> fusion
Supplemental data

REVIEW ARTICLE

Evaluating measurable residual disease in acute myeloid leukemia
Clinical Trials & Observations
Farhad Ravandi,Roland B. Walter,Sylvie D. Freeman
View Articletitled, Evaluating measurable residual disease in acute myeloid leukemia

CLINICAL TRIALS AND OBSERVATIONS

Similar telomere attrition rates in androgen-treated and untreated patients with dyskeratosis congenita
Clinical Trials & Observations
Payal P. Khincha,Alison A. Bertuch,Shahinaz M. Gadalla,Neelam Giri,Blanche P. Alter,Sharon A. Savage
View Articletitled, Similar telomere attrition rates in androgen-treated and untreated patients with dyskeratosis congenita
Safety and immunogenicity of conjugate quadrivalent meningococcal vaccination after hematopoietic cell transplantation
Clinical Trials & Observations
Matthew P. Cheng,Alisha Pandit,Joseph H. Antin,Stephen R. Walsh,Daisy Huynh,Irene M. Ghobrial,Lindsey R. Baden,Francisco M. Marty,Nicolas C. Issa
View Articletitled, Safety and immunogenicity of conjugate quadrivalent meningococcal vaccination after hematopoietic cell transplantation

HEALTH SERVICES AND OUTCOMES

Identification of patients with hemoglobin SS/Sβ0 thalassemia disease and pain crises within electronic health records
Ashima Singh,Javier Mora,Julie A. Panepinto
View Articletitled, Identification of patients with hemoglobin SS/Sβ<sup>0</sup> thalassemia disease and pain crises within electronic health records
Supplemental data
Utilization of initial chemotherapy for newly diagnosed acute myeloid leukemia in the United States
Clinical Trials & Observations
Vijaya Raj Bhatt,Valerie Shostrom,Krishna Gundabolu,James O. Armitage
View Articletitled, Utilization of initial chemotherapy for newly diagnosed acute myeloid leukemia in the United States
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Lineage tracing of murine adult hematopoietic stem cells reveals active contribution to steady-state hematopoiesis
Richard H. Chapple,Yu-Jung Tseng,Tianyuan Hu,Ayumi Kitano,Makiko Takeichi,Kevin A. Hoegenauer,Daisuke Nakada
View Articletitled, Lineage tracing of murine adult hematopoietic stem cells reveals active contribution to steady-state hematopoiesis
Supplemental data
Oncogenic N-Ras and Tet2 haploinsufficiency collaborate to dysregulate hematopoietic stem and progenitor cells
Xi Jin,Tingting Qin,Meiling Zhao,Nathanael Bailey,Lu Liu,Kevin Yang,Victor Ng,Tomoyasu Higashimoto,Rosemary Coolon,Gina Ney,Maria E. Figueroa,Qing Li
View Articletitled, Oncogenic N-Ras and Tet2 haploinsufficiency collaborate to dysregulate hematopoietic stem and progenitor cells
Supplemental data

LYMPHOID NEOPLASIA

In vivo RNAi screening identifies Pafah1b3 as a target for combination therapy with TKIs in BCR-ABL1+ BCP-ALL
Eleanor R. C. Fiedler,Arjun Bhutkar,Emily Lawler,Rana Besada,Michael T. Hemann
View Articletitled, In vivo RNAi screening identifies <em>Pafah1b3</em> as a target for combination therapy with TKIs in <em>BCR-ABL1</em><sup><em>+</em></sup> BCP-ALL
Supplemental data
Positron emission tomography–computed tomography predictors of progression after DA-R-EPOCH for PMBCL
Clinical Trials & Observations
Chelsea C. Pinnix,Andrea K. Ng,Bouthaina S. Dabaja,Sarah A. Milgrom,Jillian R. Gunther,C. David Fuller,Grace L. Smith,Zeinab Abou Yehia,Wei Qiao,Christine F. Wogan,Mani Akhtari,Osama Mawlawi,L. Jeffrey Medeiros,Hubert H. Chuang,William Martin-Doyle,Philippe Armand,Ann S. LaCasce,Yasuhiro Oki,Michelle Fanale,Jason Westin,Sattva Neelapu,Loretta Nastoupil
View Articletitled, Positron emission tomography–computed tomography predictors of progression after DA-R-EPOCH for PMBCL

MYELOID NEOPLASIA

A potent tetravalent T-cell–engaging bispecific antibody against CD33 in acute myeloid leukemia
Sayed Shahabuddin Hoseini,Hongfen Guo,Zhihao Wu,Miho Nakajima Hatano,Nai-Kong V. Cheung
View Articletitled, A potent tetravalent T-cell–engaging bispecific antibody against CD33 in acute myeloid leukemia
Supplemental data

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

Differential antibacterial control by neutrophil subsets
Pieter H. C. Leliefeld,Janesh Pillay,Nienke Vrisekoop,Marjolein Heeres,Tamar Tak,Matthijs Kox,Suzan H. M. Rooijakkers,Taco W. Kuijpers,Peter Pickkers,Luke P. H. Leenen,Leo Koenderman
View Articletitled, Differential antibacterial control by neutrophil subsets
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Activation of the vitamin D receptor transcription factor stimulates the growth of definitive erythroid progenitors
Jeffrey Barminko,Brad M. Reinholt,Alexander Emmanuelli,Alannah N. Lejeune,Margaret H. Baron
View Articletitled, Activation of the vitamin D receptor transcription factor stimulates the growth of definitive erythroid progenitors
Supplemental data

THROMBOSIS AND HEMOSTASIS

Plasma hepcidin is associated with future risk of venous thromboembolism
Clinical Trials & Observations
Trygve S. Ellingsen,Jostein Lappegård,Thor Ueland,Pål Aukrust,Sigrid K. Brækkan,John-Bjarne Hansen
View Articletitled, Plasma hepcidin is associated with future risk of venous thromboembolism
Supplemental data
A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant
Shauna L. French,Claudia Thalmann,Paul F. Bray,Lynn E. Macdonald,Andrew J. Murphy,Mark W. Sleeman,Justin R. Hamilton
View Articletitled, A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant
Supplemental data
The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice
Magdalena L. Bochenek,Tobias Bauer,Rajinikanth Gogiraju,Yona Nadir,Amrit Mann,Tanja Schönfelder,Leonie Hünig,Benjamin Brenner,Thomas Münzel,Philip Wenzel,Stavros Konstantinides,Katrin Schäfer
View Articletitled, The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice
Supplemental data
Prothrombin conversion is accelerated in the antiphospholipid syndrome and insensitive to thrombomodulin
Clinical Trials & Observations
Romy M. W. Kremers,Stéphane Zuily,Hilde Kelchtermans,Tessa C. Peters,Saartje Bloemen,Véronique Regnault,H. Coenraad Hemker,Philip G. de Groot,Denis Wahl,Bas de Laat
View Articletitled, Prothrombin conversion is accelerated in the antiphospholipid syndrome and insensitive to thrombomodulin
Supplemental data
A cross-sectional analysis of cardiovascular disease in the hemophilia population
Clinical Trials & Observations
Suman L. Sood,Dunlei Cheng,Margaret Ragni,Craig M. Kessler,Doris Quon,Amy D. Shapiro,Nigel S. Key,Marilyn J. Manco-Johnson,Adam Cuker,Christine Kempton,Tzu-Fei Wang,M. Elaine Eyster,Philip Kuriakose,Annette von Drygalski,Joan Cox Gill,Allison Wheeler,Peter Kouides,Miguel A. Escobar,Cindy Leissinger,Sarah Galdzicka,Marshall Corson,Crystal Watson,Barbara A. Konkle
View Articletitled, A cross-sectional analysis of cardiovascular disease in the hemophilia population

TRANSPLANTATION

Related donor transplants: has posttransplantation cyclophosphamide nullified the detrimental effect of HLA mismatch?
Clinical Trials & Observations
Tara M. Robinson,Ephraim J. Fuchs,Mei-Jie Zhang,Andrew St. Martin,Myriam Labopin,Daniel A. Keesler,Didier Blaise,Asad Bashey,Jean-Henri Bourhis,Fabio Ciceri,Stefan O. Ciurea,Steven M. Devine,Mohamad Mohty,Shannon R. McCurdy,Noel Milpied,Ian K. McNiece,Vanderson Rocha,Rizwan Romee,Gerard Socie,Ibrahim Yakoub-Agha,Robert J. Soiffer,Mary Eapen,Arnon Nagler,on behalf of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplant and the Center for International Blood and Marrow Transplant Research
View Articletitled, Related donor transplants: has posttransplantation cyclophosphamide nullified the detrimental effect of HLA mismatch?
Comparison of pediatric allogeneic transplant outcomes using myeloablative busulfan with cyclophosphamide or fludarabine
Clinical Trials & Observations
Andrew C. Harris,Jaap J. Boelens,Kwang Woo Ahn,Mingwei Fei,Allistair Abraham,Andrew Artz,Christopher Dvorak,Haydar Frangoul,Cesar Freytes,Robert Peter Gale,Sanghee Hong,Hillard M. Lazarus,Alison Loren,Shin Mineishi,Taiga Nishihori,Tracey O’Brien,Kirsten Williams,Marcelo C. Pasquini,John E. Levine
View Articletitled, Comparison of pediatric allogeneic transplant outcomes using myeloablative busulfan with cyclophosphamide or fludarabine
Supplemental data

ERRATUM

Kumar AJ, Kim S, Hemmer MT, et al. Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants. Blood Adv. 2018;2(9):1022-1031.
View Articletitled, Kumar AJ, Kim S, Hemmer MT, et al. Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants. <em>Blood Adv</em>. 2018;2(9):1022-1031.
  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    Immunofluorescence image showing murine hematopoietic stem cells (HSCs) stained with keratin 18 (Krt18) antibodies (red) and DAPI (4′,6-diamidino-2-phenylindole; blue). Krt18 is preferentially expressed in HSCs compared with other hematopoietic progenitor cells. See the article by Chapple et al.

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