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Journal Articles

Tissue transglutaminase drives fibrin β-chain cross-linking: a novel fibrin modification observed in trauma patients

Nana Kwame Kwabi Boateng, Riley Marie Wimberley, Jacob P Rose, Angelo D'Alessandro, Mitchell J Cohen, Ernest E Moore, Lauren Schmitt, Lauren Poole, James P. Luyendyk, Kirk C Hansen

Blood blood.2025029458.

https://doi.org/10.1182/blood.2025029458

Published: 2025

Includes: Supplemental data

Journal Articles

Structure and interactions of the proteins from the contact system

Jonas Emsley, Yujie Ma, Joost C. M. Meijers

Blood (2025) 146 (12): 1422–1430.

https://doi.org/10.1182/blood.2024025322

Published: 2025

Includes: Multimedia, Supplemental data

Journal Articles

Introduction to a review series on the structural underpinnings of hemostatic plugs and thrombotic occlusions

Thomas L. Ortel

Blood (2025) 146 (12): 1377–1378.

https://doi.org/10.1182/blood.2025030314

Published: 2025

Journal Articles

Platelet activation and signaling in thrombus formation

Frauke Swieringa, Johan W. M. Heemskerk, Alice Assinger

Blood (2025) 146 (12): 1400–1411.

https://doi.org/10.1182/blood.2024025320

Published: 2025

Includes: Supplemental data

Journal Articles

Factor XIII: driving (cross-)links in hemostasis, thrombosis, and disease

James P. Luyendyk, Matthew J. Flick, Alisa S. Wolberg

Blood (2025) 146 (12): 1412–1421.

https://doi.org/10.1182/blood.2024025321

Published: 2025

Journal Articles

Exploring the thrombus niche: lessons learned and potential therapeutic opportunities

John W. Weisel, Rustem I. Litvinov

Blood (2025) 146 (12): 1389–1399.

https://doi.org/10.1182/blood.2024025319

Published: 2025

Journal Articles

Structure-based design of therapeutics to control hemostasis

Luke J. Tucker, Krista Hilmas, Ashley C. Brown

Blood (2025) 146 (12): 1431–1439.

https://doi.org/10.1182/blood.2024025323

Published: 2025

Journal Articles

Plasminogen activation and plasmin activity are not necessary to prevent venous thrombosis/thromboembolism

Yaqiu Sang, Marzia Menegatti, Jennifer A. Brody, Kerri L. Wiggins, Brian C. Cooley, Katheryn N. Kapfer, Kadri Kangro, Bas de Laat, Flora Peyvandi, Matthew J. Flick, Nicholas L. Smith, Amy D. Shapiro, Alisa S. Wolberg

Blood (2025) 146 (11): 1346–1358.

https://doi.org/10.1182/blood.2025028680

Published: 2025

Includes: Supplemental data

Journal Articles

A bispecific nanobody for the treatment of von Willebrand disease type 1

Ivan Peyron, Caterina Casari, Genevieve McCluskey, Stéphanie Roullet, Vincent N Licari, Emilie Bocquet, Claire Auditeau, Melanie Y Daniel, Sophie Susen, Olivier D. Christophe, Peter J Lenting, Cécile V. Denis

Blood blood.2025029401.

https://doi.org/10.1182/blood.2025029401

Published: 2025

Includes: Supplemental data

Journal Articles

LRRC8 complexes are ATP release channels that regulate platelet activation and arterial thrombosis

Blood (2025) 146 (9): 1110–1126.

https://doi.org/10.1182/blood.2024026667

Published: 2025

Includes: Multimedia, Supplemental data

Journal Articles

Targeting FXR in Hepatocytes: A Promising Approach to Enhance Fibrinolysis and Reduce Deep Vein Thrombosis Risk

Bolin Li, Heze Fan, Hao Wu, Yiqiong Zhang, Ning Ding, Peining Liu, Qi Wang, Miaomiao Cao, Zixuan Meng, Xinxin Feng, Xiaozhen Zhuo, Wei Wu, Ying Xiong, Kai Deng, Ting Li, Junhui Liu, Yue Wu

Blood blood.2024027772.

https://doi.org/10.1182/blood.2024027772

Published: 2025

Includes: Supplemental data

Journal Articles

F8 gene variants influence the response to desmopressin in hemophilia A carriers

Benoît Guillet, Roseline D'Oiron, Marc Trossaert, Bénédicte Wibaut, Brigitte Pan-Petesch, Birgit Frotscher, Fabienne Genre-Volot, Laurent Ardillon, Stéphanie Desage, Céline Falaise, Christine Biron-Andreani, Vincent Cussac, Brigitte Tardy, Yoann Huguenin, Herve Chambost, Sophie Bayart, Sabine-Marie Castet, Xavier Delavenne

Blood blood.2025029829.

https://doi.org/10.1182/blood.2025029829

Published: 2025

Includes: Supplemental data

Journal Articles

The T follicular helper/T follicular helper regulatory pathway in FVIII immune responses in mice

Weiqing Jing, Jocelyn A. Schroeder, Saurabh Kumar, Juan Chen, Yuanhua Cai, Lynn M. Malec, Alexander L. Dent, Weiguo Cui, Qizhen Shi

Blood (2025) 146 (8): 998–1010.

https://doi.org/10.1182/blood.2025029470

Published: 2025

Includes: Supplemental data

Journal Articles

Factor VIIa-released extracellular vesicles attenuate joint bleed-induced hemophilic arthropathy

Padmavathi Kavadipula, Shiva Keshava, Kaushik Das, Jhansi Magisetty, Christian DeJong, Josthna Penchalaneni, Usha Pendurthi, L. Vijaya Mohan Rao

Blood blood.2024027143.

https://doi.org/10.1182/blood.2024027143

Published: 2025

Includes: Supplemental data

Journal Articles

Sequential combinations of rapid immunoassays for prompt recognition of heparin-induced thrombocytopenia

Thomas Steinauer, Elena Matthey-Guirao, Francisco J. Gomez, Luana Rittener-Ruff, Matteo Marchetti, Matthew Goodyer, Mitja Nabergoj, Stefano Barelli, Francesco Grandoni, Maxime G. Zermatten, Lorenzo Alberio

Blood (2025) 146 (7): 887–896.

https://doi.org/10.1182/blood.2024027517

Published: 2025

Includes: Supplemental data

Journal Articles

Molecular Determinants of Thrombosis Recurrence Risk Across Venous Thromboembolism Subtypes

Blood blood.2024027879.

https://doi.org/10.1182/blood.2024027879

Published: 2025

Includes: Supplemental data

Journal Articles

Cryo-EM structure of the tissue factor/factor VIIa complex with a factor X mimetic reveals a novel allosteric mechanism

Josepha C Sedzro, Amanda L. Photenhauer, Fabienne Birkle, Katarina Meze, Alex Mortenson, Cade Duckworth, Po-Chao Wen, Sarah Kearns, Michael A. Cianfrocco, Emad Tajkhorshid, Melanie D. Ohi, James H. Morrissey

Blood blood.2025029430.

https://doi.org/10.1182/blood.2025029430

Published: 2025

Includes: Multimedia, Supplemental data

Journal Articles

Genome-wide meta-analysis of heavy menstrual bleeding reveals 36 risk loci

Florian Thibord, Jason Cunha, Jelisaveta Džigurski, Bjoernar Tuftin, Jennifer E. Huffman, Natàlia Pujol-Gualdo, Kelly Cho, Peter W. F. Wilson, Jill M. Johnsen, Laura M. Raffield, Ming-Huei Chen, Triin Laisk, Andrew D. Johnson

Blood (2025) 146 (6): 745–758.

https://doi.org/10.1182/blood.2024027382

Published: 2025

Includes: Supplemental data

Journal Articles

A multiomics approach reveals novel regulators of plasma factor V levels, highlighting CLEC4M as a clearance receptor

Blood (2025) 146 (5): 628–637.

https://doi.org/10.1182/blood.2024027006

Published: 2025

Includes: Supplemental data

Journal Articles

Shear-dependent platelet aggregation by ChAdOx1 nCoV-19 vaccine: a novel biophysical mechanism for arterial thrombosis

Yiyao Catherine Chen, Naveen Eugene Louis Richard Louis, Angela Huang, Allan Sun, Alexander Dupuy, Laura Moldovan, Tiana Pelaia, Jianfang Ren, Taylor S. Cohen, Sarah C. Gilbert, Huyen Tran, Karlheinz Peter, James D. McFadyen, Lining Arnold Ju

Blood (2025) 146 (4): 496–503.

https://doi.org/10.1182/blood.2024027675

Published: 2025

Includes: Multimedia, Supplemental data

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Tissue transglutaminase drives fibrin β-chain cross-linking: a novel fibrin modification observed in trauma patients

Structure and interactions of the proteins from the contact system

Introduction to a review series on the structural underpinnings of hemostatic plugs and thrombotic occlusions

Platelet activation and signaling in thrombus formation

Factor XIII: driving (cross-)links in hemostasis, thrombosis, and disease

Exploring the thrombus niche: lessons learned and potential therapeutic opportunities

Structure-based design of therapeutics to control hemostasis

Plasminogen activation and plasmin activity are not necessary to prevent venous thrombosis/thromboembolism

A bispecific nanobody for the treatment of von Willebrand disease type 1

LRRC8 complexes are ATP release channels that regulate platelet activation and arterial thrombosis

Targeting FXR in Hepatocytes: A Promising Approach to Enhance Fibrinolysis and Reduce Deep Vein Thrombosis Risk

F8 gene variants influence the response to desmopressin in hemophilia A carriers

The T follicular helper/T follicular helper regulatory pathway in FVIII immune responses in mice

Factor VIIa-released extracellular vesicles attenuate joint bleed-induced hemophilic arthropathy

Sequential combinations of rapid immunoassays for prompt recognition of heparin-induced thrombocytopenia

Molecular Determinants of Thrombosis Recurrence Risk Across Venous Thromboembolism Subtypes

Cryo-EM structure of the tissue factor/factor VIIa complex with a factor X mimetic reveals a novel allosteric mechanism

Genome-wide meta-analysis of heavy menstrual bleeding reveals 36 risk loci

A multiomics approach reveals novel regulators of plasma factor V levels, highlighting CLEC4M as a clearance receptor

Shear-dependent platelet aggregation by ChAdOx1 nCoV-19 vaccine: a novel biophysical mechanism for arterial thrombosis

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