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Journal Articles

A New Molecular Variant in the PTGS1 Gene That Abrogates Generation of Thromboxane A2 Synthesis and Associates with Platelet Dysfunction and Bleeding

Blood (2019) 134 (Supplement_1): 2375.

https://doi.org/10.1182/blood-2019-129200

Published: 2019

Journal Articles

Defective Platelet Thromboxane A2 Signaling and Serotonin Release in the Pathogenesis of Bleeding during Viral Infection

Roberto Aiolfi, PhD, Giovanni Sitia, Matteo Iannacone, Luca Guidotti, Zaverio M. Ruggeri, MD

Blood (2019) 134 (Supplement_1): 1074.

https://doi.org/10.1182/blood-2019-128940

Published: 2019

Journal Articles

Congenital Aspirin-like Defect As a Result of Autosomal Recessive Variants in PTGS1

Suthesh Sivapalaratnam, MD PhD, Hayman Melissa, PhD, Claire Lentaigne, BSc, MB, MRCP, Melissa Chan, PhD, Marilena Crescente, PhD, Harriet Allan, Katherine Wedderburn, Moghees Hanif, Ernest Turro, PhD, Dan P Hart, PhD MBBChir, FRCPath, FRCP, Kathleen Freson, PhD, Kate Downes, PhD, NIHR Bioresource, Willem Ouwehand, MDPhD, Michael Laffan, DM, FRCP, FRCPath, Tim Warner, PhD

Blood (2018) 132 (Supplement 1): 1156.

https://doi.org/10.1182/blood-2018-99-118958

Published: 2018

Journal Articles

Protein Disulfide Isomerase Negatively Regulates Platelet Function through Modulation of the Thromboxane A2 Receptor

Noppacharn Uaprasert, MB, BCH, Oskar Eriksson, MD PhD, Robert C. Flaumenhaft, MD PhD

Blood (2017) 130 (Supplement 1): 2297.

https://doi.org/10.1182/blood.V130.Suppl_1.2297.2297

Published: 2017

Journal Articles

Cytoplasmic Phospholipase A2 Is Essential in GPVI Signaling Initiated Procoagulant Platelet Formation

Andaleb Kholmukhamedov, MD, Janecke Rae, Shawn M. Jobe, MD PhD

Blood (2017) 130 (Supplement 1): 1068.

https://doi.org/10.1182/blood.V130.Suppl_1.1068.1068

Published: 2017

Journal Articles

PTPN7 Tyrosine Phosphatase Negatively Regulates Thromboxane Generation and ERK Phosphorylation in Platelets

Vaishali Inamdar, Haritha G Reddy, BS, Carol A Dangelmaier, BS, John Kostyak, PhD, Satya P. Kunapuli, PhD

Blood (2017) 130 (Supplement 1): 1027.

https://doi.org/10.1182/blood.V130.Suppl_1.1027.1027

Published: 2017

Journal Articles

Novel Lyn-Mediated Regulation of CLEC-2 Signaling By G q -Coupled Receptors in Platelets

Rachit Badolia, PhD, Vaishali Inamdar, Bhanukanth Manne, Carol Dangelmaier, Satya P. Kunapuli, PhD

Blood (2016) 128 (22): 2536.

https://doi.org/10.1182/blood.V128.22.2536.2536

Published: 2016

Journal Articles

Thromboxane a 2 Exerts Promoting Effects on the Proliferation of Multiple Myeloma Cells By Reducing G2/M Phase Arrest through the Activation of p38/JNK MAP Kinase Pathway

Hong Xiong, PhD, Yu Yu

Blood (2015) 126 (23): 5396.

https://doi.org/10.1182/blood.V126.23.5396.5396

Published: 2015

Journal Articles

Platelet Transmission Electron Microscopy and Flow Cytometry in the Diagnosis of Congenital/Hereditary Qualitative or Quantitative Platelet Disorders

Juliana Perez Botero, MD, Laynalee K Cardel, MT, Aneel A. Ashrani, MBBS, MSc, John A. Heit, MD, Rong He, MD, C Christopher Hook, MD, Robert D McBane, II, MD, Animesh Pardanani, MBBS, PhD, Deepti M. Warad, M.B.B.S., Waldemar E Wysokinski, MD PhD, Vilmarie Rodriguez, MD, William L. Nichols, Jr., MD, Rajiv K. Pruthi, MBBS, Dong Chen, MD PhD, Mrinal M Patnaik, MBBS

Blood (2015) 126 (23): 3476.

https://doi.org/10.1182/blood.V126.23.3476.3476

Published: 2015

Journal Articles

Autotransfusion of Hemothorax Blood Is Prothrombotic but Inhibits Platelet Aggregation: A Potentiator of Disseminated Intravascular Coagulation

Aaron T. Henderson, DO, Thomas A Mitchell, MD, Andrew P Cap, MDPhD, Maryanne C Herzig, PhD, Chriselda G Fedyk, PhD

Blood (2015) 126 (23): 2345.

https://doi.org/10.1182/blood.V126.23.2345.2345

Published: 2015

Journal Articles

ASK1, a Novel Regulator of Thrombosis, Is Activated Downstream of G-Protein Coupled receptors in Human Platelets

Randall Derstine, MS, Meghna Ulhas Naik, MS, Ramya Turaga, PhD, Ulhas P Naik, PhD FAHA

Blood (2014) 124 (21): 4163.

https://doi.org/10.1182/blood.V124.21.4163.4163

Published: 2014

Journal Articles

Distinct Genetic Loci Are Associated with Platelet Aggregation Responses to Collagen and Collagen Synthetic Related Peptide (SRP) in Mice

Hayley R Waterman, Peter C Thomson, PhD, Jill M Johnsen, MD, James D Gorham, MD PhD, Matthew S Ranson, James C. Zimring, MD PhD, Adam D. Munday, PhD

Blood (2014) 124 (21): 4165.

https://doi.org/10.1182/blood.V124.21.4165.4165

Published: 2014

Journal Articles

Platelet Pitpa Is Not Essential for Hemostasis, but Is Required for Tumor Metastasis Formation

Liang Zhao, PhD, Aae Suzuki, Timothy J. Stalker, PhD, Lurong Lian, MD, Min Sang, MD, Amy C Durham, VMD, Charles S. Abrams, MD

Blood (2014) 124 (21): 342.

https://doi.org/10.1182/blood.V124.21.342.342

Published: 2014

Journal Articles

The Role Of Intraplatelet Reactive Oxygen Species In The Regulation Of Platelet Glycoprotein Ibα Ectodomain Shedding

Pingping Zhang, Juan Du, Lili Zhao, Xiujuan Wang, Yiwen Zhang, PhD, Rong Yan, PhD, Jin Dai, Guanglei Liu, Feng Zhang, Kesheng Dai, PhD

Blood (2013) 122 (21): 1061.

https://doi.org/10.1182/blood.V122.21.1061.1061

Published: 2013

Journal Articles

Thromboxane A 2 Signaling Regulates Heterogeneous Platelet Activation Following Laser-Induced Injury In Mouse Cremaster Arterioles

Jian Shen, BS, Fei Yang, MS, Yujun Shen, PhD, Ying Yu, MD, PhD, Timothy J. Stalker, PhD, Li Zhu, MD, PhD

Blood (2013) 122 (21): 1055.

https://doi.org/10.1182/blood.V122.21.1055.1055

Published: 2013

Journal Articles

High-Throughput Nanomechanical Platelet Contraction Measurements Using Patterned Hydrogels.

David R Myers, PhD, Ashley C Brown, PhD, Yongzhi Qiu, PhD, Yumiko Sakurai, MSc, Reginald Tran, BS, Byungwook Ahn, PhD, Robert Mannino, Todd Sulchek, PhD, Andew Lyon, PhD, Thomas H Barker, PhD, Wilbur Lam, MD, PhD

Blood (2012) 120 (21): 2172.

https://doi.org/10.1182/blood.V120.21.2172.2172

Published: 2012

Journal Articles

Classical PKCs Regulate ADP-Induced Thromboxane Generation by Modulating Tyrosine Phosphorylation On Novel PKC Isoform Delta Through Shptp-1

Dheeraj Bhavanasi, Carol T Dangelmaier, Jin Jianguo, Soochong Kim, PhD, Satya P. Kunapuli, Ph.D.

Blood (2012) 120 (21): 1064.

https://doi.org/10.1182/blood.V120.21.1064.1064

Published: 2012

Journal Articles

Polo-Like Kinase 3, a Novel Regulator of Thrombosis: Positive Regulation of TxA2 Generation, Granular Secretion and Clot Retraction, but Negative Regulation of Integrin Activation

Meghna Ulhas Naik, MS, Brendan Bachman, MS, John C Kostyak, Ph.D, Wei Dai, Ph.D, Ulhas P Naik, Ph.D. FAHA

Blood (2012) 120 (21): 379.

https://doi.org/10.1182/blood.V120.21.379.379

Published: 2012

Journal Articles

Platelets Protect From Lipopolysaccharide-Induced Lethal Endotoxemia by Inhibiting Macrophage-Dependent Inflammation Via the Cyclooxygenase 1 (COX1) Signaling Pathway

Binggang Xiang, PhD, Guoying Zhang, MD, Xiang-An Li, Ph.D, Andrew J. Morris, PhD, Alan Daugherty, Ph.D, Sidney W. Whiteheart, PhD, Susan S. Smyth, MD, PhD, Zhenyu Li, MD, PhD

Blood (2012) 120 (21): 93.

https://doi.org/10.1182/blood.V120.21.93.93

Published: 2012

Journal Articles

Regulator of G-protein signaling 18 integrates activating and inhibitory signaling in platelets

Kristina Gegenbauer, Giuliano Elia, Alfonso Blanco-Fernandez, Albert Smolenski

Blood (2012) 119 (16): 3799–3807.

https://doi.org/10.1182/blood-2011-11-390369

Published: 2012

NARROW

A New Molecular Variant in the PTGS1 Gene That Abrogates Generation of Thromboxane A2 Synthesis and Associates with Platelet Dysfunction and Bleeding

Defective Platelet Thromboxane A2 Signaling and Serotonin Release in the Pathogenesis of Bleeding during Viral Infection

Congenital Aspirin-like Defect As a Result of Autosomal Recessive Variants in PTGS1

Protein Disulfide Isomerase Negatively Regulates Platelet Function through Modulation of the Thromboxane A2 Receptor

Cytoplasmic Phospholipase A2 Is Essential in GPVI Signaling Initiated Procoagulant Platelet Formation

PTPN7 Tyrosine Phosphatase Negatively Regulates Thromboxane Generation and ERK Phosphorylation in Platelets

Novel Lyn-Mediated Regulation of CLEC-2 Signaling By G q -Coupled Receptors in Platelets

Thromboxane a 2 Exerts Promoting Effects on the Proliferation of Multiple Myeloma Cells By Reducing G2/M Phase Arrest through the Activation of p38/JNK MAP Kinase Pathway

Platelet Transmission Electron Microscopy and Flow Cytometry in the Diagnosis of Congenital/Hereditary Qualitative or Quantitative Platelet Disorders

Autotransfusion of Hemothorax Blood Is Prothrombotic but Inhibits Platelet Aggregation: A Potentiator of Disseminated Intravascular Coagulation

ASK1, a Novel Regulator of Thrombosis, Is Activated Downstream of G-Protein Coupled receptors in Human Platelets

Distinct Genetic Loci Are Associated with Platelet Aggregation Responses to Collagen and Collagen Synthetic Related Peptide (SRP) in Mice

Platelet Pitpa Is Not Essential for Hemostasis, but Is Required for Tumor Metastasis Formation

The Role Of Intraplatelet Reactive Oxygen Species In The Regulation Of Platelet Glycoprotein Ibα Ectodomain Shedding

Thromboxane A 2 Signaling Regulates Heterogeneous Platelet Activation Following Laser-Induced Injury In Mouse Cremaster Arterioles

High-Throughput Nanomechanical Platelet Contraction Measurements Using Patterned Hydrogels.

Classical PKCs Regulate ADP-Induced Thromboxane Generation by Modulating Tyrosine Phosphorylation On Novel PKC Isoform Delta Through Shptp-1

Polo-Like Kinase 3, a Novel Regulator of Thrombosis: Positive Regulation of TxA2 Generation, Granular Secretion and Clot Retraction, but Negative Regulation of Integrin Activation

Platelets Protect From Lipopolysaccharide-Induced Lethal Endotoxemia by Inhibiting Macrophage-Dependent Inflammation Via the Cyclooxygenase 1 (COX1) Signaling Pathway

Regulator of G-protein signaling 18 integrates activating and inhibitory signaling in platelets

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American Society of Hematology

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American Society of Hematology

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