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Journal Articles

CD44 loss of function sensitizes AML cells to the BCL-2 inhibitor venetoclax by decreasing CXCL12-driven survival cues

Xiaobing Yu, Leonel Munoz-Sagredo, Karolin Streule, Patricia Muschong, Elisabeth Bayer, Romina J. Walter, Julia C. Gutjahr, Richard Greil, Miguel L. Concha, Carsten Müller-Tidow, Tanja N. Hartmann, Véronique Orian-Rousseau

Blood (2021) 138 (12): 1067–1080.

https://doi.org/10.1182/blood.2020006343

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Extracellular vesicles shed by follicular lymphoma B cells promote polarization of the bone marrow stromal cell niche

Erwan Dumontet, Céline Pangault, David Roulois, Matthis Desoteux, Simon Léonard, Tony Marchand, Maelle Latour, Patricia Legoix, Damarys Loew, Florent Dingli, Joelle Dulong, Erwan Flecher, Cédric Coulouarn, Guillaume Cartron, Thierry Fest, Karin Tarte

Blood (2021) 138 (1): 57–70.

https://doi.org/10.1182/blood.2020008791

Published: 2021

Includes: Supplemental data

Journal Articles

B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL

Gregory Lazarian, PharmD, Shanye Yin, PhD, Elisa Ten Hacken, PhD, Tomasz Sewastianik, MSc,PhD, Alba Font-tello, PhD, Heather Joyal, Elizabeth Witten, Mei Zheng, Christopher J. Ott, PhD, Donna S Neuberg, ScD, Lili Wang, MD PhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD

Blood (2019) 134 (Supplement_1): 848.

https://doi.org/10.1182/blood-2019-123963

Published: 2019

Journal Articles

Local Irradiation Induces Systemic Inflammatory Response and Alteration of the Hematopoietic Stem Cell Niche

Yuko Kawano, MD PhD, Daniel K Byun, BS, Benjamin J. Frisch, PhD, Hiroki Kawano, MD PhD, Mark W LaMere, BA, Carl J. Johnston, PhD, Jaqueline P. Williams, PhD, Laura M. Calvi, MD

Blood (2019) 134 (Supplement_1): 1213.

https://doi.org/10.1182/blood-2019-131809

Published: 2019

Journal Articles

Stringent Small Molecule Dose Requirements for the Optimal Expansion of Hematopoietic Stem Cells Revealed By Predictive Analytics and Xenotransplants

Javed K Manesia, PhD, Sakhar Almoflehi, Roya Pasha, Suria Jahan, MSc, John Blake, PhD, Julie Audet, PhD, Nicolas Pineault, PhD

Blood (2019) 134 (Supplement_1): 1185.

https://doi.org/10.1182/blood-2019-128692

Published: 2019

Journal Articles

Identifying the Leukemia Stem Cell Niche Mediating Drug Resistance in Flt3-ITD Acute Myeloid Leukemia

Nick R Anderson, BS, Hui Li, BS, Mason W Harris, Shaowei Qiu, MD, Andrew J Paterson, PhD, Ravi Bhatia, MD

Blood (2019) 134 (Supplement_1): 909.

https://doi.org/10.1182/blood-2019-124379

Published: 2019

Journal Articles

Molecular Characterization of Bone Marrow and Peripheral Blood Compartments from Patients with Plasma Cell Leukemia in the Mmrf Commpass Study

Sheri Skerget, PhD, Austin Christofferson, BSc, Sara Nasser, PhD, Christophe Legendre, PhD, The MMRF CoMMpass Network, Jennifer Yesil, Daniel Auclair, Sagar Lonial, Jonathan J Keats, PhD

Blood (2019) 134 (Supplement_1): 1782.

https://doi.org/10.1182/blood-2019-130697

Published: 2019

Journal Articles

R4 Rgs Subfamily Proteins Suppress Engraftment and Regulate SDF-1/CXCR4 Signaling in Human CD34+ Hematopoietic Stem/Progenitor Cells

Kathy Chan, PhD, Tsin Sik Wong, Mphil, Karen Li, PhD, Xiao-Bing Zhang, PhD, Ronald Wang, PhD, King Yiu Lee, PhD, Frankie Wai Tsoi Cheng, MD, Chi Kong Li, MBBS,MD, Kam Tong Leung, PhD

Blood (2019) 134 (Supplement_1): 1927.

https://doi.org/10.1182/blood-2019-129498

Published: 2019

Journal Articles

Distinct Bone Marrow Microenvironment Abnormalities in MDS and MPN with Fibrosis

Cao Sy Luan, MS, Yoshiaki Takahoko, MS, Hidekazu Nishikii, MD PhD, Naoshi Obara, MD PhD, Tatsuhiro Sakamoto, MD PhD, Takayasu Kato, MD PhD, Keiichiro Hattori, MD PhD, Ryota Matsuoka, MD PhD, Shingo Sakashita, MD PhD, Yasuhito Nannya, MD PhD, Hideki Makishima, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Seishi Ogawa, MD PhD, Shigeru Chiba, MD PhD

Blood (2019) 134 (Supplement_1): 2976.

https://doi.org/10.1182/blood-2019-129423

Published: 2019

Journal Articles

Therapeutic Targeting of CCR1 to Prevent Dissemination of Multiple Myeloma Plasma Cells

Mara N Zeissig, BS, Duncan R Hewett, PhD, Krzysztof M Mrozik, PhD, Vasilios Panagopoulos, PhD, Monika Engelhardt, MD, Luen Bik To, MBBS, FRACP, FRCPA, PhD, Peter J Croucher, PhD, Andrew CW Zannettino, PhD, Kate Vandyke, PhD

Blood (2019) 134 (Supplement_1): 3099.

https://doi.org/10.1182/blood-2019-121974

Published: 2019

Journal Articles

The Vasculopathy in the Bone Marrow Microenvironment of Humanized Sickle Cell Mice Is Reversible By Blood Transfusion

Shin-Young Park, PhD, Alessandro Mattè, BSc,PhD, Yookyung Jung, PhD, Jina Ryu, PhD, Wilson Anand, Eun Young Anna Han, B.S., Min Liu, M.S., Carmine Carbone, Davide Melisi, Takashi Nagasawa, Charles Lin, PhD, Leslie E. Silberstein, MD, Lucia De Franceschi, MD

Blood (2019) 134 (Supplement_1): 2256.

https://doi.org/10.1182/blood-2019-123532

Published: 2019

Journal Articles

CXCR4 Inhibition with BL-8040 in Combination with Nelarabine in Patients with Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia / Lymphoblastic Lymphoma

Geoffrey L. Uy, MD, Tapan M. Kadia, MD, Wendy Stock, MD, Jonathan E Brammer, MD, Osnat Bohana-Kashtan, PhD, Abi Vainstein, Ella Sorani, PhD, Hemda Chen, PharmD, John F. DiPersio, MD PhD, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 2630.

https://doi.org/10.1182/blood-2019-127121

Published: 2019

Journal Articles

Tipifarnib Modulates Interferon (IFN)-γ-Inducible Genes in Acute Myeloid Leukemia

Jayakumar Vadakekolathu, PhD, Stephen Reeder, BSc, Clare Coveney, PhD, Sergio Rutella, MDPhDFRCPath

Blood (2019) 134 (Supplement_1): 2726.

https://doi.org/10.1182/blood-2019-124717

Published: 2019

Journal Articles

Single Cell Transcriptomic Analysis of the Multiple Myeloma Bone Marrow Identifies a Unique Inflammatory Stromal Cell Population Associated with TNF Signaling

Madelon M.E. de Jong, MD, Zoltan Kellermayer, MD PhD, Natalie Papazian, M Duin, Annemiek Broyl, MD PhD, Pieter Sonneveld, Tom Cupedo

Blood (2019) 134 (Supplement_1): 690.

https://doi.org/10.1182/blood-2019-123012

Published: 2019

Journal Articles

TGF-β Signaling Contributes to Myelofibrosis and Clonal Dominance of Myeloproliferative Neoplasms

Juo-Chin Yao, Grazia Abou Ezzi, PhD, Joseph R. Krambs, BS, Salil Uttarwar, Eric J. Duncavage, MD, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 470.

https://doi.org/10.1182/blood-2019-128943

Published: 2019

Journal Articles

Proof of Concept for Tipifarnib in Relapsed or Refractory Angioimmunoblastic T-Cell Lymphoma (AITL) and CXCL12+ Peripheral T-Cell Lymphoma (PTCL): Preliminary Results from an Open-Label, Phase 2 Study

Blood (2019) 134 (Supplement_1): 468.

https://doi.org/10.1182/blood-2019-128513

Published: 2019

Journal Articles

p53 Mediated Bone Marrow Mesenchymal Stem Cell Expansion Supports Acute Myeloid Leukemia Development

Rasoul Pourebrahimabadi, MD PhD, Zoe Alaniz, Lauren B Ostermann, Hung Alex Luong, Rafael Heinz Montoya, Peter P. Ruvolo, PhD, Steven M. Kornblau, MD, Joseph D. Khoury, MD, Carlos E. Bueso-Ramos, MD PhD, Michael Andreeff, MD PhD

Blood (2019) 134 (Supplement_1): 523.

https://doi.org/10.1182/blood-2019-127245

Published: 2019

Journal Articles

An Adapting Bone Marrow Niche Creates a Nurturing Environment for Hematopoiesis during Immune Thrombocytopenia Progression

Oliver Herd, BSc, Maria Abril Arredondo Garcia, BSc, James Hewitson, PhD, Karen Hogg, PhD, Saleni Pravin Kumar, BSc, Katiuska Pulgar Prieto, BSc, Andrew Stone, BSc, Paul Genever, PhD, Ian Hitchcock, PhD

Blood (2019) 134 (Supplement_1): 222.

https://doi.org/10.1182/blood-2019-129795

Published: 2019

Journal Articles

DNMT3A R882 Alters the Epigenome of Hematopoietic Cells

Amanda M Smith, PhD, Taylor LaValle, BS, Shamika Ketkar, PhD, Sai Mukund Ramakrishnan, MS, Christopher A Miller, PhD, Timothy J Ley, MD

Blood (2019) 134 (Supplement_1): 112.

https://doi.org/10.1182/blood-2019-129003

Published: 2019

Journal Articles

Macrophage Transfer to HSCs Assigns Residence in Bone Marrow

Xin GAO, PhD, Philip Boulais, PhD, Masato Tanaka, Christopher Richard Marlein, PhD, Paul S. Frenette, MD

Blood (2019) 134 (Supplement_1): 276.

https://doi.org/10.1182/blood-2019-123762

Published: 2019

NARROW

CD44 loss of function sensitizes AML cells to the BCL-2 inhibitor venetoclax by decreasing CXCL12-driven survival cues

Extracellular vesicles shed by follicular lymphoma B cells promote polarization of the bone marrow stromal cell niche

B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL

Local Irradiation Induces Systemic Inflammatory Response and Alteration of the Hematopoietic Stem Cell Niche

Stringent Small Molecule Dose Requirements for the Optimal Expansion of Hematopoietic Stem Cells Revealed By Predictive Analytics and Xenotransplants

Identifying the Leukemia Stem Cell Niche Mediating Drug Resistance in Flt3-ITD Acute Myeloid Leukemia

Molecular Characterization of Bone Marrow and Peripheral Blood Compartments from Patients with Plasma Cell Leukemia in the Mmrf Commpass Study

R4 Rgs Subfamily Proteins Suppress Engraftment and Regulate SDF-1/CXCR4 Signaling in Human CD34+ Hematopoietic Stem/Progenitor Cells

Distinct Bone Marrow Microenvironment Abnormalities in MDS and MPN with Fibrosis

Therapeutic Targeting of CCR1 to Prevent Dissemination of Multiple Myeloma Plasma Cells

The Vasculopathy in the Bone Marrow Microenvironment of Humanized Sickle Cell Mice Is Reversible By Blood Transfusion

CXCR4 Inhibition with BL-8040 in Combination with Nelarabine in Patients with Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia / Lymphoblastic Lymphoma

Tipifarnib Modulates Interferon (IFN)-γ-Inducible Genes in Acute Myeloid Leukemia

Single Cell Transcriptomic Analysis of the Multiple Myeloma Bone Marrow Identifies a Unique Inflammatory Stromal Cell Population Associated with TNF Signaling

TGF-β Signaling Contributes to Myelofibrosis and Clonal Dominance of Myeloproliferative Neoplasms

Proof of Concept for Tipifarnib in Relapsed or Refractory Angioimmunoblastic T-Cell Lymphoma (AITL) and CXCL12+ Peripheral T-Cell Lymphoma (PTCL): Preliminary Results from an Open-Label, Phase 2 Study

p53 Mediated Bone Marrow Mesenchymal Stem Cell Expansion Supports Acute Myeloid Leukemia Development

An Adapting Bone Marrow Niche Creates a Nurturing Environment for Hematopoiesis during Immune Thrombocytopenia Progression

DNMT3A R882 Alters the Epigenome of Hematopoietic Cells

Macrophage Transfer to HSCs Assigns Residence in Bone Marrow

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American Society of Hematology

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ASH Publications

American Society of Hematology

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