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Matthew RM Jotte
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Journal Articles

Combined Inhibition of CXCR4 Signaling and System x c - Transporter Activity Induces Synthetic Lethality in T-ALL Cells By Suppressing Gsh and Inducing Ferroptosis

Jun Xia, PhD, Stephanie Sun, Matthew RM Jotte, Geoffrey L Uy, MD, Ella Sorani, PhD, Abi Vainstein, Liron Shemesh Davish, Katherine E Caldwell, William G Hawkins, Daniel C. Link, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37.
https://doi.org/10.1182/blood-2020-142735
Published: 2020
Journal Articles

CXCR4 Blockade By BL-8040 in T Cell Acute Lymphoblastic Leukemia Decreases Mitochondrial Mass and Induces Non-Apoptotic Cell Death

Jun Xia, PhD, Stephanie Sun, Matthew RM Jotte, Geoffrey L. Uy, MD, Osnat Bohana-Kashtan, PhD, Ella Sorani, PhD, Abi Vainstein, Amnon Peled, PhD, Daniel C. Link, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2745.
https://doi.org/10.1182/blood-2019-128881
Published: 2019
Journal Articles

The CXCR4 Antagonist, BL8040, Is Highly Active Against Human T-ALL in Preclinical Models

Jun Xia, PhD, Matthew RM Jotte, Stephanie Sun, Geoffrey L. Uy, MD, Abi Vainstein, Ella Sorani, PhD, Osnat Bohana-Kashtan, PhD, Stephen Shaw, PhD, Daniel C. Link, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2700.
https://doi.org/10.1182/blood-2018-99-117213
Published: 2018
Journal Articles

Cellular Stressors Contribute to the Expansion of Multiple Hematopoietic Clones of Varying Leukemic Potential

Terrence N Wong, MD PhD, Christopher A Miller, PhD, Matthew RM Jotte, Nusayba Bagegni, MD, Jack D Baty, Amy E Schmidt, MDPhD, Amanda F Cashen, MD, Eric J. Duncavage, MD, Nichole M Helton, Mark A. Fiala, BS, Robert S Fulton, Sharon E Heath, Megan Janke, PhD, Kierstin Luber, Peter Westervelt, MDPhD, Ravi Vij, MDMBA, John F DiPersio, MD PhD, John S. Welch, MD PhD, Timothy A. Graubert, MD, Matthew J. Walter, MD, Timothy James J Ley, MD, Daniel C. Link, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 469.
https://doi.org/10.1182/blood.V130.Suppl_1.469.469
Published: 2017