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Journal Articles

Pharmacokinetic and Pharmacodynamic Study of NKTR-255, a Polymer-Conjugated Human IL-15, in Cynomolgus Monkey

Takahiro Miyazaki, Peiwen Kuo, Mekhala Maiti, Palakshi Obalapur, Murali Addepalli, Werner Rubas, Paul Sims, Ping Zhang, Mario Q. Marcondes, MD PhD, Loui Madakamutil, Jonathan Zalevsky

Blood (2018) 132 (Supplement 1): 2952.

https://doi.org/10.1182/blood-2018-99-115638

Published: 2018

Journal Articles

hLL2-Cys-PBD, a New Site-Specifically Conjugated, Pyrrolobenzodiazepine (PBD) Dimer-Based Antibody Drug Conjugate (ADC) Targeting CD22-Expressing B-Cell Malignancies.

Francesca Zammarchi, PhD, Simon Corbett, Lauren Adams, Maria Mellinas-Gomez, PhD, Peter Tyrer, PhD, Sandamali Dissanayake, Simone Sims, Karin Havenith, PhD, Simon Chivers, PhD, David G Willimas, PhD, Philip W Howard, PhD, John A. Hartley, PhD, Patrick van Berkel, PhD

Blood (2016) 128 (22): 4176.

https://doi.org/10.1182/blood.V128.22.4176.4176

Published: 2016

Journal Articles

Concomitant Suppression of IKZF1, IRF4 and MYC Contribute to the Anti-Tumor Activity of the BET Inhibitor, Cpi-0610, in Disease Models of Multiple Myeloma

Ka Tat Siu, PhD, Janani Ramachandran, MA, Andrew J. Yee, MD, Homare Eda, MD PhD, Loredana Santo, MD, Elizabeth K. O'Donnell, MD, Cristina Panaroni, PhD, Jennifer Mertz, PhD, Robert J. Sims, PhD, Michael Cooper, MD, Noopur Raje, MD

Blood (2016) 128 (22): 3320.

https://doi.org/10.1182/blood.V128.22.3320.3320

Published: 2016

Journal Articles

Effect of the BET Inhibitor, Cpi-0610, Alone and in Combination with Lenalidomide in Multiple Myeloma

Ka Tat Siu, PhD, Homare Eda, MDPhD, Loredana Santo, MD, Janani Ramachandran, MA, Miroslav Koulnis, PhD, Jennifer Mertz, PhD, Robert J. Sims, PhD, Michael Cooper, MD, Noopur S. Raje, MD

Blood (2015) 126 (23): 4255.

https://doi.org/10.1182/blood.V126.23.4255.4255

Published: 2015

Journal Articles

Flippases and Scramblases at Plasma Membranes that Regulate Phosphatidylserine Exposure

Shigekazu Nagata, PhD

Blood (2015) 126 (23): SCI-31.

https://doi.org/10.1182/blood.V126.23.SCI-31.SCI-31

Published: 2015

Journal Articles

BET Inhibitor CPI-0610 Is Well Tolerated and Induces Responses in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma: Preliminary Analysis of an Ongoing Phase 1 Study

Jeremy S. Abramson, MD, Kristie A. Blum, MD, Ian W. Flinn, MD PhD, Martin Gutierrez, MD, Andre Goy, MD, Michael Maris, MD, Michael Cooper, MD, Michael O'Meara, MS, Darrell Borger, PhD, Jennifer Mertz, PhD, Robert J. Sims, PhD, Supko Jeffrey, PhD, Anas Younes, MD

Blood (2015) 126 (23): 1491.

https://doi.org/10.1182/blood.V126.23.1491.1491

Published: 2015

Journal Articles

Palmitic Acid, As Verified Using Lipid Profiling By Secondary Ion Mass Spectrometry, Demonstrates Anti-Tumor Activity Against Multiple Myeloma

Yasuyuki Nagata, MD, Itsuko Ishizaki, Michihiko Waki, Yoshimi Ide, MD PhD, Md Amir Hossen, Kazunori Ohnishi, MD PhD, Mitsutoshi Setou, MD PhD

Blood (2014) 124 (21): 5683.

https://doi.org/10.1182/blood.V124.21.5683.5683

Published: 2014

Journal Articles

Development of BET Protein Bromodomain Inhibition for the Treatment of Hematologic Malignancies

Robert Sims, PhD, Emmanuel Normant, PharmD, PhD, Peter Sandy, PhD, Jennifer Mertz, PhD, Barbara Bryant, PhD, Michael O'Meara, MS, Marie Green, PhD, Michael Cooper, MD, Jim Audia, PhD

Blood (2012) 120 (21): 1331.

https://doi.org/10.1182/blood.V120.21.1331.1331

Published: 2012

Journal Articles

Matched Case Control Analysis Comparing Long Term Survival of Multiple Myeloma Patients Who Received Stem Cell Transplant with and without Idiotype-Pulsed Dendritic Cell Vaccine

Yi Lin, MD PhD, Morie A Gertz, MD, Robert B. Sims, MD, Sumithra Mandrekar, PhD, Kristina Laumann, Betsy LaPlant, Angela Dispenzieri, MD, Suzanne R Hayman, MD, Francis K Buadi, M.D., David Dingli, M.D., Ph.D., Douglas Padley, Dennis A. Gastineau, MD, Shaji Kumar, MD, Vincent Rajkumar, MD, Martha Q Lacy, MD

Blood (2011) 118 (21): 636.

https://doi.org/10.1182/blood.V118.21.636.636

Published: 2011

Journal Articles

Mobilizing Agents G-CSF, Cyclophosphamide or AMD3100 (Plerixafor) Have Distinct Effects on Osteoblasts, Hematopoietic Stem Cell Niches, and B-Lymphopoiesis,

Jean-Pierre Levesque, PhD, Linda J. Bendall, BSc, PhD, Allison R Pettit, PhD, Liza Raggatt, PhD, Rebecca Jacobsen, BSc, Valerie Barbier, Bianca Nowlan, Yi Shen, PhD, Natalie A Sims, PhD, Ingrid G Winkler, PhD

Blood (2011) 118 (21): 4005.

https://doi.org/10.1182/blood.V118.21.4005.4005

Published: 2011

Journal Articles

Increased Gamma Globulin Following Immunotherapy with Sipuleucel-T Is Associated with Antigen-Specific Antibody Responses

Robert B. Sims, MD, Mark H. Wener, MD, Corazon P. dela Rosa, Lisa R. C. Lin, Nadeem A. Sheikh, PhD

Blood (2010) 116 (21): 1738.

https://doi.org/10.1182/blood.V116.21.1738.1738

Published: 2010

Journal Articles

Elevated Eosinophils Following Treatment with Sipuleucel-T In Men with Prostate Cancer Is Associated with Antigen-Specific Immune Response and Prolonged Survival.

Robert B. Sims, MD, Lisa R. C. Lin, Corazon P. dela Rosa, Nadeem A. Sheikh, PhD, James B. Whitmore, PhD, Mark W. Frohlich, MD

Blood (2010) 116 (21): 1491.

https://doi.org/10.1182/blood.V116.21.1491.1491

Published: 2010

Journal Articles

Apoptosis and the DNA Damage Response: The Role of the RB Tumor Suppressor Pathway in Oxidative Stress Responses in the Hematopoietic System.

Kay F. Macleod, PhD

Blood (2009) 114 (22): SCI-15.

https://doi.org/10.1182/blood.V114.22.SCI-15.SCI-15

Published: 2009

NARROW

Pharmacokinetic and Pharmacodynamic Study of NKTR-255, a Polymer-Conjugated Human IL-15, in Cynomolgus Monkey

hLL2-Cys-PBD, a New Site-Specifically Conjugated, Pyrrolobenzodiazepine (PBD) Dimer-Based Antibody Drug Conjugate (ADC) Targeting CD22-Expressing B-Cell Malignancies.

Concomitant Suppression of IKZF1, IRF4 and MYC Contribute to the Anti-Tumor Activity of the BET Inhibitor, Cpi-0610, in Disease Models of Multiple Myeloma

Effect of the BET Inhibitor, Cpi-0610, Alone and in Combination with Lenalidomide in Multiple Myeloma

Flippases and Scramblases at Plasma Membranes that Regulate Phosphatidylserine Exposure

BET Inhibitor CPI-0610 Is Well Tolerated and Induces Responses in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma: Preliminary Analysis of an Ongoing Phase 1 Study

Palmitic Acid, As Verified Using Lipid Profiling By Secondary Ion Mass Spectrometry, Demonstrates Anti-Tumor Activity Against Multiple Myeloma

Development of BET Protein Bromodomain Inhibition for the Treatment of Hematologic Malignancies

Matched Case Control Analysis Comparing Long Term Survival of Multiple Myeloma Patients Who Received Stem Cell Transplant with and without Idiotype-Pulsed Dendritic Cell Vaccine

Mobilizing Agents G-CSF, Cyclophosphamide or AMD3100 (Plerixafor) Have Distinct Effects on Osteoblasts, Hematopoietic Stem Cell Niches, and B-Lymphopoiesis,

Increased Gamma Globulin Following Immunotherapy with Sipuleucel-T Is Associated with Antigen-Specific Antibody Responses

Elevated Eosinophils Following Treatment with Sipuleucel-T In Men with Prostate Cancer Is Associated with Antigen-Specific Immune Response and Prolonged Survival.

Apoptosis and the DNA Damage Response: The Role of the RB Tumor Suppressor Pathway in Oxidative Stress Responses in the Hematopoietic System.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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