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Journal Articles

Identification Cause of Aberrant Splicing and Novel Drug Targets in Patients with Multiple Myeloma

Sophia Adamia, PhD, Teru Hideshima, MD PhD, Kenneth C Anderson, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4340.
https://doi.org/10.1182/blood.V130.Suppl_1.4340.4340
Published: 2017
Journal Articles

An IGF2BP3-Cdk9 Pathway Governs the Human Fetal-Adult Megakaryocyte Transition

Kamaleldin E Elagib, MBBS, PhD, Chih-Huan Lu, BS, Goar Mosoyan, Ewelina Zasadzińska, MS, Daniel R Foltz, PhD, Peter Balogh, Els Verhoeyen, Miriam Sansó, PhD, Robert P Fisher, MD PhD, Camelia Iancu-Rubin, PhD, Adam N Goldfarb, MD
Journal: Blood
Blood (2016) 128 (22): 886.
https://doi.org/10.1182/blood.V128.22.886.886
Published: 2016
Journal Articles

Mechanistic Role of HEXIM1 Induction in BRD4-Antagonist Mediated Growth Inhibition, Differentiation and in Vivo Lethal Activity Against Human AML Blast Progenitor Cells

Santhana G. T. Devaraj, PhD, Warren Fiskus, PhD, Bhavin Shah, Sunil Sharma, Jun Qi, PhD, Baohua Sun, MD PhD, Saikat Saha, PhD, Swaminathan Padmanabhan Iyer, MD, Youli Zu, MD PhD, James Bradner, MD, Kapil N. Bhalla, MD
Journal: Blood
Blood (2014) 124 (21): 3534.
https://doi.org/10.1182/blood.V124.21.3534.3534
Published: 2014
Journal Articles

The Distinctive Morphogenesis of Infantile Megakaryopoiesis Is Associated with Altered P-TEFb Regulation By the Oncofetal Factor IGF2BP3

Kamaleldin E Elagib, MBBS, PhD, Chih-Huan Lu, Ewelina Zasadzińska, MSc, Daniel R Foltz, PhD, Peter Balogh, MSc, Adam N Goldfarb, MD
Journal: Blood
Blood (2014) 124 (21): 2911.
https://doi.org/10.1182/blood.V124.21.2911.2911
Published: 2014
Journal Articles

Aberration Of SF3B1 Results In Deregulated Splicing Of Key Genes and Pathways In Myelodysplastic Syndromes

Hamid Dolatshad, PhD, Marta Fernandez-Mercado, PhD, Bon Ham Yip, PhD, Chris J Smith, PhD, Martin Attwood, BSc, MRes, Cristina Di Genua, BSc, Natasha Sahgal, PhD, Bartlomiej P Przychodzen, PhD, Elli Papaemmanuil, PhD, Alexander A Kanapin, PhD, Helen Lockstone, PhD, Peter J. Campbell, PhD, Jaroslaw P. Maciejewski, MD, PhD, Andrea Pellagatti, PhD, Jacqueline Boultwood
Journal: Blood
Blood (2013) 122 (21): 2747.
https://doi.org/10.1182/blood.V122.21.2747.2747
Published: 2013
Journal Articles

Apparent Involvement Of The Interferon, RNA Processing, and Wnt Signaling Pathways In Monoclonal B Lymphocytosis

Xiao-Jie Yan, MD PhD, Claudia Fazi, PhD, Scarfo Lydia, MD, Wentian Li, Ph.D., Jonathan E. Kolitz, MD, Jacqueline C. Barrientos, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Paolo Ghia, MD, PhD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2013) 122 (21): 4157.
https://doi.org/10.1182/blood.V122.21.4157.4157
Published: 2013
Journal Articles

Whole Exome Sequencing Reveals Acquired SF3B1 Mutations Defining Patients with Acquired Idiopathic Sideroblastic Anaemia

Alexander E Smith, PhD, Syed A Mian, Austin G Kulasekararaj, Azim M Mohamedali, PhD, Ghulam J. Mufti, MD
Journal: Blood
Blood (2011) 118 (21): 2793.
https://doi.org/10.1182/blood.V118.21.2793.2793
Published: 2011
Journal Articles

Calpain Drives Megakaryopoiesis by Targeting the 7SK snRNP Complex: A Connection to Down Syndrome Megakaryocytic Neoplasia

Kamaleldin Elagib, PhD, Jeremy D. Rubinstein, Lorrie L. Delehanty, Peter A. Greer, PhD, Shuran Li, Jae K. Lee, PhD, Ivailo S. Mihaylov, PhD, Zhe Li, PhD, Stuart H. Orkin, MD, Adam Goldfarb, MD
Journal: Blood
Blood (2011) 118 (21): 552.
https://doi.org/10.1182/blood.V118.21.552.552
Published: 2011
Journal Articles

Acquired Molecular Defects in Spliceosome Machinery: Novel Pathogenetic Pathways in Myeloid Leukemogenesis

Hideki Makishima, MD, PhD, Hirotoshi Sakaguchi, MD, Valeria Visconte, PhD, Andres Jerez, MD, Anna M Jankowska, PhD, Kathryn M Guinta, Hideki Muramatsu, MD, PhD, Mikkael A Sekeres, MD, Seiji Kojima, MD, PhD, Ramon V. Tiu, MD, Jaroslaw P. Maciejewski, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 271.
https://doi.org/10.1182/blood.V118.21.271.271
Published: 2011
Journal Articles

Fox-2A Modulates Protein 4.1R Exon 16 5' Splice Site Activation.

Shu-Ching Huang, Guang Yang, PhD, Jennie Park, Alexander Ou, Edward J. Benz, Jr., MD
Journal: Blood
Blood (2009) 114 (22): 778.
https://doi.org/10.1182/blood.V114.22.778.778
Published: 2009
Journal Articles

Chronic Lymphocytic Leukemia Cells Recognize Conserved Epitopes Associated with Apoptosis and Catabolic Chemical Modifications

Rosa Catera, Gregg J. Silverman, Katerina Hatzi, Till Seiler, Sebastien Didier, Lu Zhang, MA, Maxime Hervé, Eric Meffre, David Graham Oscier, MD, Helen Vlassara, Yifang Chen, Steven L. Allen, Kanti R. Rai, MD, Charles C. Chu, PhD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2008) 112 (11): 3150.
https://doi.org/10.1182/blood.V112.11.3150.3150
Published: 2008
Journal Articles

The Unique Pattern of Somatic Imprint in Oct-4 + Very Small Embryonic Like (VSEL) Stem Cells Isolated from Adult Tissues Further Supports Both Their Epiblast/Germ Line Origin and Explains Quiescent Status: Potential Modification of Somatic Imprint as a Key to Longevity?

Dong-Myung Shin, Ph.D., Ewa K Zuba-Surma, Ph.D., Mariusz Z Ratajczak, M.D., Ph.D., Magdalena Kucia
Journal: Blood
Blood (2008) 112 (11): 385.
https://doi.org/10.1182/blood.V112.11.385.385
Published: 2008
Journal Articles

U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7

Emina Savarese, Ohk-wha Chae, Simon Trowitzsch, Gert Weber, Berthold Kastner, Shizuo Akira, Hermann Wagner, Roland M. Schmid, Stefan Bauer, Anne Krug
Journal: Blood
Blood (2006) 107 (8): 3229–3234.
https://doi.org/10.1182/blood-2005-07-2650
Published: 2006