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Journal Articles

CTX-712, a Novel Clk Inhibitor Targeting Myeloid Neoplasms with SRSF2 Mutation

Akinori Yoda, PhD, Daisuke Morishita, PhD, Akio Mizutani, PhD, Yoshihiko Satoh, PhD, Yotaro Ochi, MD, Yasuhito Nannya, MD PhD, Hideki Makishima, MD PhD, Hiroshi Miyake, PhD, Seishi Ogawa, MD PhD

Blood (2019) 134 (Supplement_1): 404.

https://doi.org/10.1182/blood-2019-131559

Published: 2019

Journal Articles

Aberrant RHAMM Splicing in Multiple Myeloma (MM) and Its Implications for Immunotherapy

Daisuke Ogiya, MD PhD, Lisa Müller, Sigitas J Verselis, PhD, Heiner Schaal, PhD, Ivane Abiatari, MD, Ana M Stenstrom, Catherine A Nicholas, John F Daley, Michael P. Chu, David M. Dorfman, MD PhD, Linda M. Pilarski, PhD, Teru Hideshima, MD PhD, Kenneth C. Anderson, MD, Sophia Adamia, PhD

Blood (2019) 134 (Supplement_1): 1804.

https://doi.org/10.1182/blood-2019-131775

Published: 2019

Journal Articles

The Biological and Clinical Implications of the Alternative Splicing Landscape of 1,258 Myeloid Neoplasm Cases

Courtney E Hershberger, BS, Devlin C Moyer, BS, Wencke Walter, PhD, Stephan Hutter, PhD, Claudia Haferlach, MD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Richard A Padgett, PhD

Blood (2019) 134 (Supplement_1): 769.

https://doi.org/10.1182/blood-2019-128278

Published: 2019

Journal Articles

Cell Type-Specific Deregulation of Polypyrimidine Tract- Binding Proteins (PTBPs) Drive Aberrant Splicing in Multiple Myeloma (MM) and Acute Myeloid Leukemia (AML)

Sophia Adamia, PhD, Sigitas J Verselis, PhD, Teru Hideshima, MD PhD, Michael P. Chu, MD, Shruti Bhatt, PhD, David P. Steensma, MD, Daniel J Deangelo, Richard M. Stone, MD, Daniel G. Tenen, MD, Linda M. Pilarski, PhD, James D. Griffin, MD, Kenneth Anderson, MD

Blood (2018) 132 (Supplement 1): 3895.

https://doi.org/10.1182/blood-2018-99-118501

Published: 2018

Journal Articles

Genomic Analysis of Myelodysplastic Syndromes Among Nagasaki Atomic Bomb Survivors

Blood (2018) 132 (Supplement 1): 4341.

https://doi.org/10.1182/blood-2018-99-113735

Published: 2018

Journal Articles

Synthetic Lethality CRISPR Screens in Isogenic iPSCs with Splicing Factor Gene Mutations

Henrik Sperber, PhD, Shailee Vora, BS, MS, Andriana G. Kotini, PhD, Malgorzata Olszewska, MS, Aleksandra Wroblewska, PhD, Brian Brown, PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 3083.

https://doi.org/10.1182/blood-2018-99-111857

Published: 2018

Journal Articles

A Detailed Alternate Splicing Landscape in Multiple Myeloma with Significant Potential Biological and Clinical Implications

Anil Aktas Samur, PhD, Mehmet Kemal Samur, PhD, Stephane Minvielle, PhD, Florence Magrangeas, Mariateresa Fulciniti, PhD, Raphael Szalat, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Michel Attal, Philippe Moreau, Giovanni Parmigiani, PhD, Herve Avet-Loiseau, MD PhD, Nikhil C Munshi, MD

Blood (2016) 128 (22): 356.

https://doi.org/10.1182/blood.V128.22.356.356

Published: 2016

Journal Articles

Isogenic iPSC Models of SRSF2 -Mutant Myelodysplastic Syndrome Capture Disease Phenotypes, Splicing Defects and Drug Responses

Chan-Jung Chang, PhD, Andriana Kotini, PhD, Julie Teruya-Feldstein, MD, Omar Abdel-Wahab, MD, Robert Bradley, PhD, Eirini P. Papapetrou, MD PhD

Blood (2016) 128 (22): 962.

https://doi.org/10.1182/blood.V128.22.962.962

Published: 2016

Journal Articles

Functional and Clinical Impact of Splicing Factor Dysregulation in Multiple Myeloma

Mariateresa Fulciniti, Mehmet Kemal Samur, PhD, Naim Ur Rashid, PhD, Rajya Lakshmi Bandi, MS, Manoj Bhasin, PhD, Giovanni Parmigiani, PhD, Kenneth C Anderson, MD, Nikhil C. Munshi, MD

Blood (2015) 126 (23): 726.

https://doi.org/10.1182/blood.V126.23.726.726

Published: 2015

Journal Articles

Different Mutant Splicing Factors Cause Distinct Missplicing Events and Give Rise to Different Clinical Phenotypes in Myelodysplastic Syndromes

Yusuke Shiozawa, MD, Luca Malcovati, MD, Aiko Sato-Otsubo, Anna Gallì, Kenichi Yoshida, MD PhD, Tetsuichi Yoshizato, MD, Yusuke Sato, MD PhD, Keisuke Kataoka, MD PhD, Masashi Sanada, MD PhD, Hideki Makishima, MD PhD, Yuichi Shiraishi, MD PhD, Kenichi Chiba, BA, Satoru Miyano, MD PhD, Eva Hellström Lindberg, MD PhD, Seishi Ogawa, MD PhD, Mario Cazzola, MD

Blood (2015) 126 (23): 139.

https://doi.org/10.1182/blood.V126.23.139.139

Published: 2015

Journal Articles

Regulation of CD19 Exon 2 Inclusion in B-Lymphoid Cells By Splicing Factors and Epigenetic Marks

Kathryn Black, PhD, Elena Sotillo, PhD, Nicole Martinez, Matthew Gazzara, Alejandro Barrera, Yoseph Barash, PhD, Kristen Lynch, PhD, Andrei Thomas-Tikhonenko, PhD

Blood (2015) 126 (23): 2425.

https://doi.org/10.1182/blood.V126.23.2425.2425

Published: 2015

Journal Articles

Comprehensive Analysis of Aberrant RNA Splicing in Myelodysplastic Syndromes

Yusuke Shiozawa, MD, Sato Sato-Otsubo, Anna Gallì, Kenichi Yoshida, MD PhD, Tetsuichi Yoshizato, MD, Yusuke Sato, MD, Keisuke Kataoka, MD PhD, Masashi Sanada, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Satoru Miyano, PhD, Luca Malcovati, MD, Mario Cazzola, MD, Seishi Ogawa, MD PhD

Blood (2014) 124 (21): 826.

https://doi.org/10.1182/blood.V124.21.826.826

Published: 2014

Journal Articles

Aberrant Splicing In Patients With AML Is Associated With Over- Expression Of Specific Splicing Factors

Sophia Adamia, PhD, Christian Bach, Ph.D., Patrick M Pilarski, Martha Wadleigh, MD, David P. Steensma, MD, Gabriela Motyckova, MD, PhD, Daniel J. DeAngelo, MD, Ph.D, Richard M. Stone, MD, Daniel G. Tenen, MD, James D. Griffin, MD

Blood (2013) 122 (21): 3749.

https://doi.org/10.1182/blood.V122.21.3749.3749

Published: 2013

Journal Articles

Functional and Molecular Impact Of Dp1-Dependent Alternate Splicing In Multiple Myeloma

Mariateresa Fulciniti, PhD, Manoj Bashin, Ph.D, Mehmet Kemal Samur, PhD, Rajya Bandi, Parantu K Shah, PhD, Antonia Cagnetta, MD, Cheng Li, PhD, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Herve Avet-Loiseau, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 1845.

https://doi.org/10.1182/blood.V122.21.1845.1845

Published: 2013

Journal Articles

Genome-Wide Aberrant Splicing in Patients with Acute Myelold Leukemia (AML) Is Associated with Altered Expression of Splicing Factors

Sophia Adamia, PhD, Hervé Avet-Loiseau, MD, PhD, Jana Jakubikova, Suzan Lazo-Kallanian, John Daley, PhD, Laurence Lode, Ph.D, Ilene Galinsky, ANP, Richard M. Stone, MD, James D. Griffin, MD

Blood (2012) 120 (21): 652.

https://doi.org/10.1182/blood.V120.21.652.652

Published: 2012

Journal Articles

Deferiprone Is Associated with Lower Serum Ferritin (SF) Relative to Liver Iron Concentration (LIC) Than Deferoxamine and Deferasirox- Implications for Clinical Practice

Ai Leen Ang, MBBS, Farrukh T Shah, MD, Bernard A Davis, MD, Alison Thomas, MBBCh, BA, Govin Murugachandran, MBBS, BSc, Jeevan Kumuradevan, MBChB, Maciej W Garbowksi, LekMed, John B Porter, MD

Blood (2010) 116 (21): 4246.

https://doi.org/10.1182/blood.V116.21.4246.4246

Published: 2010

Journal Articles

Identification Genetic Variations (GVs) Causing Splicing of TNF Family Members and Adaptor Proteins That Modulate NFkB Pathways in Waldenstrom’s Maroglobulinemia (WM).

Sophia Adamia, PhD, Lian Xu, Antonio Sacco, Steven Treon, MD, Ph.D

Blood (2007) 110 (11): 2516.

https://doi.org/10.1182/blood.V110.11.2516.2516

Published: 2007

Journal Articles

Key differences in TLR3/poly I:C signaling and cytokine induction by human primary cells: a phenomenon absent from murine cell systems

Anna M. Lundberg, Stefan K. Drexler, Claudia Monaco, Lynn M. Williams, Sandra M. Sacre, Marc Feldmann, Brian M. Foxwell

Blood (2007) 110 (9): 3245–3252.

https://doi.org/10.1182/blood-2007-02-072934

Published: 2007

Includes: Supplemental data

Journal Articles

Long-Term Outcome of Iron-Induced Cardiac Disease in Patients with Thalassemia Major Treated with Combined DFP/DFO or DFO Alone.

Maria Eliana Lai, MD, Stefania Vacquer, MD, Alessia Pepe, MD, Aurelio Maggio, MD, Maria P. Carta, MD, Paolo Cianciulli, MD, Patrizio Bina, MD, Franco Sau, MD, Robert W. Grady, PhD

Blood (2006) 108 (11): 1764.

https://doi.org/10.1182/blood.V108.11.1764.1764

Published: 2006

Journal Articles

Serum Ferritin in Children with Sickle Cell Disease on Chronic Transfusion: Measure of Iron Overload or End Organ Injury? STOP/STOP II Liver Iron Ancillary Study.

Tom Adamkiewicz, MD, Miguel R. Abboud, MD, Julio C. Barredo, MD, Melanie Kirby-Allen, MD, Ofelia A. Alvarez, MD, James F. Casella, MD, Rathi V. Iyer, MD, Virgil McKie, MD, Gerald Milton Woods, MD, Abdullah Kutlar, MD, Carole Paley, MD, Jessica Peterson, Elizabeth Rackoff, Manuela Merelles-Pulcini, Elizabeth Dackiw, Kristin Stegenga, Nadine Odo, Mimi Lou, Robert J. Adams, MD

Blood (2006) 108 (11): 791.

https://doi.org/10.1182/blood.V108.11.791.791

Published: 2006

NARROW

CTX-712, a Novel Clk Inhibitor Targeting Myeloid Neoplasms with SRSF2 Mutation

Aberrant RHAMM Splicing in Multiple Myeloma (MM) and Its Implications for Immunotherapy

The Biological and Clinical Implications of the Alternative Splicing Landscape of 1,258 Myeloid Neoplasm Cases

Cell Type-Specific Deregulation of Polypyrimidine Tract- Binding Proteins (PTBPs) Drive Aberrant Splicing in Multiple Myeloma (MM) and Acute Myeloid Leukemia (AML)

Genomic Analysis of Myelodysplastic Syndromes Among Nagasaki Atomic Bomb Survivors

Synthetic Lethality CRISPR Screens in Isogenic iPSCs with Splicing Factor Gene Mutations

A Detailed Alternate Splicing Landscape in Multiple Myeloma with Significant Potential Biological and Clinical Implications

Isogenic iPSC Models of SRSF2 -Mutant Myelodysplastic Syndrome Capture Disease Phenotypes, Splicing Defects and Drug Responses

Functional and Clinical Impact of Splicing Factor Dysregulation in Multiple Myeloma

Different Mutant Splicing Factors Cause Distinct Missplicing Events and Give Rise to Different Clinical Phenotypes in Myelodysplastic Syndromes

Regulation of CD19 Exon 2 Inclusion in B-Lymphoid Cells By Splicing Factors and Epigenetic Marks

Comprehensive Analysis of Aberrant RNA Splicing in Myelodysplastic Syndromes

Aberrant Splicing In Patients With AML Is Associated With Over- Expression Of Specific Splicing Factors

Functional and Molecular Impact Of Dp1-Dependent Alternate Splicing In Multiple Myeloma

Genome-Wide Aberrant Splicing in Patients with Acute Myelold Leukemia (AML) Is Associated with Altered Expression of Splicing Factors

Deferiprone Is Associated with Lower Serum Ferritin (SF) Relative to Liver Iron Concentration (LIC) Than Deferoxamine and Deferasirox- Implications for Clinical Practice

Identification Genetic Variations (GVs) Causing Splicing of TNF Family Members and Adaptor Proteins That Modulate NFkB Pathways in Waldenstrom’s Maroglobulinemia (WM).

Key differences in TLR3/poly I:C signaling and cytokine induction by human primary cells: a phenomenon absent from murine cell systems

Long-Term Outcome of Iron-Induced Cardiac Disease in Patients with Thalassemia Major Treated with Combined DFP/DFO or DFO Alone.

Serum Ferritin in Children with Sickle Cell Disease on Chronic Transfusion: Measure of Iron Overload or End Organ Injury? STOP/STOP II Liver Iron Ancillary Study.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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