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Journal Articles

Involvement of RUNX1 Pathway Is a Common Event in the Leukemic Transformation of Chronic Myeloproliferative Neoplasms (MPNs)

Paola Guglielmelli, MD PhD, Niccolò Bartalucci, PhDBSc, Elisa Contini, PhD, Giada Rotunno, PhD, Annalisa Pacilli, PhD, Simone Romagnoli, BSc, Lara Mannelli, MD, Francesco Mannelli, MD, Giacomo Coltro, MD, Alessandro Pancrazzi, PhD, Valentina Ariu, BSci, Sara Fiaccabrino, Roberto Semeraro, Alberto Magi, PhD, Carmela Mannarelli, PhD, Francesca Gesullo, BSci, Chiara Paoli, PhD, Alessandro M. Vannucchi, MD

Blood (2019) 134 (Supplement_1): 2968.

https://doi.org/10.1182/blood-2019-129094

Published: 2019

Journal Articles

gata2 is Required for the runx1 -Independent Hematopoiesis in Zebrafish

Erica Bresciani, PhD, Blake Carrington, Erika M Kwon Kim, PhD, Kai Yu, PhD, Kevin Bishop, Stefania Dell'Orso, PhD, Vittorio Sartorelli, PhD, Raman B. Sood, PhD, Paul P. Liu, MD PhD

Blood (2019) 134 (Supplement_1): 2463.

https://doi.org/10.1182/blood-2019-127334

Published: 2019

Journal Articles

Strategies for Analysis of Novel Molecular Variants in the RUNX1 Gene As a Cause of Familial Platelet Disorder with Predisposition to Acute Myeloid Leukemia (FPD/AML)

Veronica Palma-Barqueros, MSc, Jf Ruiz-Pividal, MSc, Jose Maria Bastida, MD PhD, Natalia Bohdan, MJ Lopez-Andreu, PhD, Raul Teruel-Montoya, PhD, Ana Isabel Antón, PhD, Francisca Ferrer Marin, MD PhD, Jose Padilla, Rosa Cifuentes-Riquelme, A Marín-Quilez, MSc, Marta Martín Izquierdo, MSc, Rocio Benito, PhD, Vicente Vicente, MD PhD, Jesus Maria . Hernández-Rivas, MD, José Ramón González-Porras, MD PhD, Jose Rivera, PhD, Maria Luisa Lozano, MD PhD

Blood (2019) 134 (Supplement_1): 2359.

https://doi.org/10.1182/blood-2019-128736

Published: 2019

Journal Articles

Clinical and Cytogenomic Features of Lymphoblastic Leukemia with Intrachromosomal Amplification of Chromosome 21 (iAMP21) in the Context of Constitutional Ring Chromosome 21

Tatiana Tvrdik, PhD MSc, Kristian T. Schafernak, MD MPH, Jeffrey R Jacobsen, MD, Reha Toydemir, MD PhD, Alexandra M Walsh, MD, Bo Hong, MD

Blood (2019) 134 (Supplement_1): 5208.

https://doi.org/10.1182/blood-2019-123766

Published: 2019

Journal Articles

Targeted Disruption of the Cohesin Subunit STAG2 Leads to Loss of Insulation and Inappropriate Gene Activation in Response to Differentiation Signals

Jisha Antony, PhD, Gregory Giminez, PhD, Umaima Khatoon, BSc (Hons), Robert Day, PhD, Ian Morison, PhD, FRCPA, MBBS, Julia Horsfield, PhD

Blood (2018) 132 (Supplement 1): 878.

https://doi.org/10.1182/blood-2018-99-117965

Published: 2018

Journal Articles

RUNX1 Mutations Identify an Entity of Blast Phase Chronic Myeloid Leukemia (BP-CML) Patients with Distinct Phenotype, Transcriptional Profile and Drug Vulnerabilities

Shady Awad, MD, Matti Kankainen, PhD, Olli Dufva, Caroline A Heckman, PhD, Kimmo Porkka, MD PhD, Satu Mustjoki, MD PhD

Blood (2018) 132 (Supplement 1): 4257.

https://doi.org/10.1182/blood-2018-99-111602

Published: 2018

Journal Articles

Global Chromatin Occupancy and Epigenetic Signature Analysis Reveal New Insights into the Function of GATA1 N-Terminus in Erythropoiesis

Te Ling, PhD, Yehudit Birger, PhD, Monika Stankiewicz, PhD, Nissim Ben-Haim, Itamar Kanter, Tomer Kalisky, Avigail Rein Gil, MD, Neil L Kelleher, PhD, Lihua Zou, PhD, Shai Izraeli, MD, John D. Crispino, PhD MBA

Blood (2018) 132 (Supplement 1): 533.

https://doi.org/10.1182/blood-2018-99-115338

Published: 2018

Journal Articles

Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control of A4GALT

Julia S. Westman, Linn Stenfelt, Karina Vidovic, Mattias Möller, Åsa Hellberg, Sven Kjellström, Martin L. Olsson

Blood (2018) 131 (14): 1611–1616.

https://doi.org/10.1182/blood-2017-08-803080

Published: 2018

Includes: Supplemental data

Journal Articles

Cross Talk between Ikaros and RUNX1 in Myeloid Leukemia

Jessica L. Heath, MD, Jamie L. Deutsch, Gabriel M. Cohn, Joshua T. Rose, Gary S. Stein, PhD, Sayyed K. Zaidi, PhD, Seth E. Frietze, PhD

Blood (2017) 130 (Supplement 1): 3789.

https://doi.org/10.1182/blood.V130.Suppl_1.3789.3789

Published: 2017

Journal Articles

RUNX1 Mutations Lead to a Myeloid Differentiation Block in Association with Enhanced Proliferation By Altering the RUNX1 Transcriptional Program

Mylène Gerritsen, MSc, Esther Tijchon, PhD, Guoqiang Yi, PhD, Jorren Kuster, BSc, Jan Jacob Schuringa, PhD, Joost H.A. Martens, Edo Vellenga, MD

Blood (2017) 130 (Supplement 1): 1229.

https://doi.org/10.1182/blood.V130.Suppl_1.1229.1229

Published: 2017

Journal Articles

Crispr Engineering in CD34+ Progenitors Reveals Cis-Acting Regulatory Regions Mediating 3D Interactions and Stem Cell Fate Decisions

Mira Jeong, PhD, Yong Lei, PhD, Ivan Bochkov, Muhammad S Shamim, B.S., Anna G Guzman, Su-Chen Huang, M.S., Olga Dudchenko, PhD, Ido Machol, Michael C Gundry, BS, Huthayfa Mujahed, MS.c, Soren Lehmann, Erez S Lieberman, PhD, Margaret A Goodell, PhD

Blood (2016) 128 (22): 1466.

https://doi.org/10.1182/blood.V128.22.1466.1466

Published: 2016

Journal Articles

A Runx1 Interactome Identifies Novel Hematopoietic Enhancers

Judith Marsman, PhD, Amarni L Thomas, MSc, Motomi Osato, MD PhD, Justin M O'Sullivan, PhD, Julia A Horsfield, PhD

Blood (2016) 128 (22): 726.

https://doi.org/10.1182/blood.V128.22.726.726

Published: 2016

Journal Articles

Cluster Regulation of RUNX Family By "Gene Switch" Triggers a Profound Tumor Regression of Diverse Origins

Ken Morita, MD, PhD, Kensho Suzuki, Shintaro Maeda, Yoshihide Mitsuda, Ayaka Yano, Yoshimi Yamada, Hiroki Kiyose, Chieko Tokushige, Paul P. Liu, MD PhD, Souichi Adachi, MD, PhD, Hiroshi Sugiyama, PhD, Yasuhiko Kamikubo, MD, PhD

Blood (2016) 128 (22): 443.

https://doi.org/10.1182/blood.V128.22.443.443

Published: 2016

Journal Articles

Human NOTCH4 Is a Key Target of RUNX1 in Megakaryocytic Differentiation

Yueying Li, MD, Chen Jin, Hao Bai, Shu Sun, Paul P. Liu, MD PhD, Linzhao Cheng, PhD, Qianfei Wang, PhD

Blood (2016) 128 (22): 425.

https://doi.org/10.1182/blood.V128.22.425.425

Published: 2016

Journal Articles

Runx1 downregulates stem cell and megakaryocytic transcription programs that support niche interactions

Kira Behrens, Ioanna Triviai, Maike Schwieger, Nilgün Tekin, Malik Alawi, Michael Spohn, Daniela Indenbirken, Marion Ziegler, Ursula Müller, Warren S. Alexander, Carol Stocking

Blood (2016) 127 (26): 3369–3381.

https://doi.org/10.1182/blood-2015-09-668129

Published: 2016

Includes: Supplemental data

Journal Articles

The Roles of RUNX1 in Human Hematopoiesis and Megakaryopoiesis Revealed By Genome-Targeted Human iPSCs and an Improved Hematopoietic Differentiation Model

Bin-Kuan Chou, PhD, Hao Bai, PhD, Yongxing Gao, Ying Wang, Zhaohui Ye, PhD, Erika Mijin Kwon, PhD, Pu Paul Liu, MD PhD, Alan D. Friedman, MD, Zack Z. Wang, PhD, Linzhao Cheng, PhD

Blood (2015) 126 (23): 1167.

https://doi.org/10.1182/blood.V126.23.1167.1167

Published: 2015

Journal Articles

Novel RUNX1 Mutation in a Family with an Uncharacterized Secretion Defect

M. Badin, BSc, C. P.M. Hayward, MD PhD, S. Tasneem, PhD, G. Pare, MD MSc, A. D. Paterson, MD, J. Waye, PhD

Blood (2015) 126 (23): 3458.

https://doi.org/10.1182/blood.V126.23.3458.3458

Published: 2015

Journal Articles

Association of the RUNX1/AML1 Gene Mutation and Familial MDS/AML: A Case Report and Review of Literature

Wancheng Chen, Hongbo Li

Blood (2015) 126 (23): 4807.

https://doi.org/10.1182/blood.V126.23.4807.4807

Published: 2015

Journal Articles

AML with RUNX1 Mutations and Loss of RUNX1 Wild-Type - a Distinct Subset?

Claudia Haferlach, MD, Niroshan Nadarajah, M.Sc., Annette Fasan, PhD, Karolína Perglerová, Wolfgang Kern, MD, Susanne Schnittger, PhD, Torsten Haferlach

Blood (2015) 126 (23): 2578.

https://doi.org/10.1182/blood.V126.23.2578.2578

Published: 2015

Journal Articles

Runx1 Maintains Granulocytic-Monocytic Progenitor Numbers By Negatively Regulating Interactions with the Stem Cell Niche

Carol Stocking, Kira Behrens, Birte Niebuhr, Ursula Mueller

Blood (2014) 124 (21): 2913.

https://doi.org/10.1182/blood.V124.21.2913.2913

Published: 2014

NARROW

Involvement of RUNX1 Pathway Is a Common Event in the Leukemic Transformation of Chronic Myeloproliferative Neoplasms (MPNs)

gata2 is Required for the runx1 -Independent Hematopoiesis in Zebrafish

Strategies for Analysis of Novel Molecular Variants in the RUNX1 Gene As a Cause of Familial Platelet Disorder with Predisposition to Acute Myeloid Leukemia (FPD/AML)

Clinical and Cytogenomic Features of Lymphoblastic Leukemia with Intrachromosomal Amplification of Chromosome 21 (iAMP21) in the Context of Constitutional Ring Chromosome 21

Targeted Disruption of the Cohesin Subunit STAG2 Leads to Loss of Insulation and Inappropriate Gene Activation in Response to Differentiation Signals

RUNX1 Mutations Identify an Entity of Blast Phase Chronic Myeloid Leukemia (BP-CML) Patients with Distinct Phenotype, Transcriptional Profile and Drug Vulnerabilities

Global Chromatin Occupancy and Epigenetic Signature Analysis Reveal New Insights into the Function of GATA1 N-Terminus in Erythropoiesis

Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control of A4GALT

Cross Talk between Ikaros and RUNX1 in Myeloid Leukemia

RUNX1 Mutations Lead to a Myeloid Differentiation Block in Association with Enhanced Proliferation By Altering the RUNX1 Transcriptional Program

Crispr Engineering in CD34+ Progenitors Reveals Cis-Acting Regulatory Regions Mediating 3D Interactions and Stem Cell Fate Decisions

A Runx1 Interactome Identifies Novel Hematopoietic Enhancers

Cluster Regulation of RUNX Family By "Gene Switch" Triggers a Profound Tumor Regression of Diverse Origins

Human NOTCH4 Is a Key Target of RUNX1 in Megakaryocytic Differentiation

Runx1 downregulates stem cell and megakaryocytic transcription programs that support niche interactions

The Roles of RUNX1 in Human Hematopoiesis and Megakaryopoiesis Revealed By Genome-Targeted Human iPSCs and an Improved Hematopoietic Differentiation Model

Novel RUNX1 Mutation in a Family with an Uncharacterized Secretion Defect

Association of the RUNX1/AML1 Gene Mutation and Familial MDS/AML: A Case Report and Review of Literature

AML with RUNX1 Mutations and Loss of RUNX1 Wild-Type - a Distinct Subset?

Runx1 Maintains Granulocytic-Monocytic Progenitor Numbers By Negatively Regulating Interactions with the Stem Cell Niche

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American Society of Hematology

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American Society of Hematology

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