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Journal Articles

Mitochondrial Activity Identifies a Transcriptionally and Functionally Distinct Subset of Aged HSCs with Lineage-Balanced Output

Els Mansell, PhD, Valgardur Sigurdsson, PhD, Elitza Deltcheva, PhD, John Brown, PhD, Chela James, PhD, Kenichi Miharada, PhD, Shamit Soneji, PhD, Jonas Larsson, MD PhD, Tariq Enver, PhD

Blood (2019) 134 (Supplement_1): 2480.

https://doi.org/10.1182/blood-2019-124001

Published: 2019

Journal Articles

Excessive R-Loops Trigger an Inflammatory Cascade Leading to Aberrant Hematopoietic Stem and Progenitor Cell Expansion

Joshua Weinreb, MSc, Varun Gupta, Teresa V. Bowman, PhD

Blood (2019) 134 (Supplement_1): 772.

https://doi.org/10.1182/blood-2019-124888

Published: 2019

Journal Articles

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

Yamamoto Keita, MD, Susumu Goyama, MD PhD, Shuhei Asada, MD PhD, Takeshi Fujino, MD, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, MD, Ayana Kon, MD PhD, Yasuhito Nannya, MD PhD, Seishi Ogawa, MD PhD, Reina Onoguchi, PhD, Nobuyoshi Akimitsu, PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 2514.

https://doi.org/10.1182/blood-2019-125472

Published: 2019

Journal Articles

Regulation of Erythroblast Protein Expression By an RNA Splicing Mechanism, Decoy Exon-Mediated Intron Retention

Marilyn Parra, Weiguo Zhang, PhD, Jonathan Vu, Mark DeWitt, John G Conboy, PhD

Blood (2019) 134 (Supplement_1): 3504.

https://doi.org/10.1182/blood-2019-131153

Published: 2019

Journal Articles

Characterizing Dyskeratosis Congenita Caused By Parn Mutations in the Zebrafish

Anna Cordeiro, PhD, Adam P Deveau, MSc, Santhosh Dhanraj, PhD, Yigal Dror, MDFRCPC, Jason Berman, MD

Blood (2019) 134 (Supplement_1): 3744.

https://doi.org/10.1182/blood-2019-130147

Published: 2019

Journal Articles

Splicing Control in Normal and Aberrant Erythropoiesis

Esther Obeng, MD PhD

Blood (2018) 132 (Supplement 1): SCI-47.

https://doi.org/10.1182/blood-2018-99-109414

Published: 2018

Journal Articles

Different Classes of ABL1 Fusions Activate Different Downstream Signalling Nodes

Lauren M Brown, BSc, Hannah Huckstep, BSc, Jarrod Sandow, PhD, Ray C Bartolo, PhD, Nadia Davidson, PhD, Breon Schmidt, BSc, Stefan Bjelosevic, BSc, Ricky W Johnstone, PhD, Alicia Oshlack, PhD, Melissa Davis, PhD, Paul G Ekert

Blood (2018) 132 (Supplement 1): 2628.

https://doi.org/10.1182/blood-2018-99-117844

Published: 2018

Journal Articles

The Non-Canonical, R-Loop Regulatory Function of PIWIL4 Maintains Genomic Integrity and Leukemic Potential of AML Cells

Shiva Bamezai, PhD, Naidu Vegi, PhD, Alex Pulikkottil Jose, Julia Müller, BSc., Ingrid Grummt, Chenlin Song, PhD, Konstanze Döhner, MD, Hartmut Döhner, MD, Michaela Feuring-Buske, MD, Vijay Pal Singh Rawat, PhD, Christian Buske, MD

Blood (2018) 132 (Supplement 1): 879.

https://doi.org/10.1182/blood-2018-99-113281

Published: 2018

Journal Articles

Characteristic Amino Acid and Energy Metabolism in AML Stem Cells As Revealed By Quantitative Multiplex Proteomics

Simon Raffel, MD, Jenny Hansson, Mattia Falcone, Christoph Lutz, Oliver Bischel, MD, Anthony D Ho, Jeroen Krijgsveld, Andreas Trumpp, Prof, PhD

Blood (2018) 132 (Supplement 1): 2780.

https://doi.org/10.1182/blood-2018-99-117046

Published: 2018

Journal Articles

Spliceosomal Mutations Induce R Loop-Associated ATR Signaling

Wan Yee Leong, PhD, Hai Dang Nguyen, PhD, Weiling Li, PhD, Matthew J. Walter, MD, Lee Zou, PhD, Timothy A. Graubert, MD

Blood (2017) 130 (Supplement 1): 116.

https://doi.org/10.1182/blood.V130.Suppl_1.116.116

Published: 2017

Journal Articles

The Spliceosomal Component Sf3b1is Essential for Hematopoietic Stem Cell Formation through the Regulation of the Jak/Stat Signaling Pathway

Teresa V. Bowman, PhD, Rosannah C. Cameron, PhD, Kathryn S Potts, PhD BS, Mia McKinstry, Varun Gupta, Xiaoying Bai, PhD

Blood (2017) 130 (Supplement 1): 2427.

https://doi.org/10.1182/blood.V130.Suppl_1.2427.2427

Published: 2017

Journal Articles

Emerging mechanisms of long noncoding RNA function during normal and malignant hematopoiesis

Juan R. Alvarez-Dominguez, Harvey F. Lodish

Blood (2017) 130 (18): 1965–1975.

https://doi.org/10.1182/blood-2017-06-788695

Published: 2017

Includes: Supplemental data

Journal Articles

Displacement of Coilin in Cajal Body Is Related to Drug Resistance of Childhood Acute Lymphoblastic Leukemia

Zhixia Yue, Yaoyao Song, Jing Niu, Shuguang Liu, PhD, Wei Ding

Blood (2016) 128 (22): 5143.

https://doi.org/10.1182/blood.V128.22.5143.5143

Published: 2016

Journal Articles

SRSF1 Is a Mediator of Radiation-Induced Alternative Splicing in B-Lymphocytes

Niema Razavian, Vivian Cheung, MD

Blood (2016) 128 (22): 1341.

https://doi.org/10.1182/blood.V128.22.1341.1341

Published: 2016

Journal Articles

Ribosomal Protein Rpl22 Regulates Development and Transformation Via Altering RNA Processing

Minshi Wang, PhD, Zheng Ser, Shuyun Rao, PhD, Shawn Fahl, Yong Zhang, Suraj Peri, PhD, Alex Kentsis, MD PhD, David L Wiest, PhD

Blood (2016) 128 (22): 3878.

https://doi.org/10.1182/blood.V128.22.3878.3878

Published: 2016

Journal Articles

Targeting PYK2 Mediates Microenvironment-Specific Myeloma Cell Death

Mark B Meads, PhD, Bin Fang, PhD, Linda Mathews, Jennifer Gemmer, MS, Liang Nong, MD, Ismael Rosado-Lopez, Tuan Nguyen, Jennifer E. Ring, William Matsui, MD, Robert MacLeod, PhD, David T. Weaver, PhD, Jonathan A. Pachter, PhD, Lori A. Hazlehurst, PhD, John M. Koomen, PhD, Kenneth H. Shain, MD PhD

Blood (2015) 126 (23): 3008.

https://doi.org/10.1182/blood.V126.23.3008.3008

Published: 2015

Journal Articles

Acute Myeloid Leukemia in the Elderly Is Characterized By a Distinct Genetic Landscape

Patricia Silva, Martin Neumann, MD, Sebastian Vosberg, Cornelia Schlee, Konstandina Isaakidis, Michael P Schroeder, Jutta Ortiz-Tánchez, Lars R. Fransecky, Teresa Hartung, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Gerhard Ehninger, Hubert Serve, MD, Wolfgang E Berdel, MD, Philipp A. Greif, Christoph Röllig, MD, Claudia D Baldus, MD

Blood (2015) 126 (23): 804.

https://doi.org/10.1182/blood.V126.23.804.804

Published: 2015

Journal Articles

The Erythroid Intron Retention Program Encompasses Developmentally Stable and Dynamic Networks and Regulates Diverse Gene Classes

Harold Pimentel, MA, BS, Marilyn Parra, Sherry Gee, Narla Mohandas, D.Sc., Lior Pachter, John G. Conboy, PhD

Blood (2015) 126 (23): 3331.

https://doi.org/10.1182/blood.V126.23.3331.3331

Published: 2015

Journal Articles

Deletion of Nono, a Novel Double-Strand Break Repair Factor, Leads to Hematopoietic Stem Cell Defects

Liliana Souza, PharmD PhD, Shuyi Li, MDPhD, Erica Silva, PhD, Zhentian Li, PhD, Shu Feng-jue, PhD, Hairong Xiong, PhD, William S. Dynan, PhD, Morgan L. McLemore, MD

Blood (2014) 124 (21): 478.

https://doi.org/10.1182/blood.V124.21.478.478

Published: 2014

Journal Articles

Targeting PYK2 Mediates Microenvironment-Specific Myeloma Cell Death

Kenneth H. Shain, MD PhD, Mark B Meads, PhD, Bin Fang, PhD, Linda Mathews, Jennifer Gemmer, Liang Nong, MD, Ismael Rosado-Lopez, BS, Jennifer E. Ring, Robert MacLeod, PhD, Lori Hazlehurst, PhD, Conor Lynch, PhD, Jonathan A. Pachter, PhD, William Matsui, MD, John Koomen, PhD, Tuan Nguyen

Blood (2014) 124 (21): 2081.

https://doi.org/10.1182/blood.V124.21.2081.2081

Published: 2014

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Mitochondrial Activity Identifies a Transcriptionally and Functionally Distinct Subset of Aged HSCs with Lineage-Balanced Output

Excessive R-Loops Trigger an Inflammatory Cascade Leading to Aberrant Hematopoietic Stem and Progenitor Cell Expansion

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

Regulation of Erythroblast Protein Expression By an RNA Splicing Mechanism, Decoy Exon-Mediated Intron Retention

Characterizing Dyskeratosis Congenita Caused By Parn Mutations in the Zebrafish

Splicing Control in Normal and Aberrant Erythropoiesis

Different Classes of ABL1 Fusions Activate Different Downstream Signalling Nodes

The Non-Canonical, R-Loop Regulatory Function of PIWIL4 Maintains Genomic Integrity and Leukemic Potential of AML Cells

Characteristic Amino Acid and Energy Metabolism in AML Stem Cells As Revealed By Quantitative Multiplex Proteomics

Spliceosomal Mutations Induce R Loop-Associated ATR Signaling

The Spliceosomal Component Sf3b1is Essential for Hematopoietic Stem Cell Formation through the Regulation of the Jak/Stat Signaling Pathway

Emerging mechanisms of long noncoding RNA function during normal and malignant hematopoiesis

Displacement of Coilin in Cajal Body Is Related to Drug Resistance of Childhood Acute Lymphoblastic Leukemia

SRSF1 Is a Mediator of Radiation-Induced Alternative Splicing in B-Lymphocytes

Ribosomal Protein Rpl22 Regulates Development and Transformation Via Altering RNA Processing

Targeting PYK2 Mediates Microenvironment-Specific Myeloma Cell Death

Acute Myeloid Leukemia in the Elderly Is Characterized By a Distinct Genetic Landscape

The Erythroid Intron Retention Program Encompasses Developmentally Stable and Dynamic Networks and Regulates Diverse Gene Classes

Deletion of Nono, a Novel Double-Strand Break Repair Factor, Leads to Hematopoietic Stem Cell Defects

Targeting PYK2 Mediates Microenvironment-Specific Myeloma Cell Death

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