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Journal Articles

Pediatric Preclinical Testing Consortium Evaluation of the Novel Anti-Microtubule Drug E7130 in Xenograft Models of Early T-Cell Precursor Acute Lymphoblastic Leukemia

Richard B. Lock, PhD, Kathryn Evans, Connor D Jones, Narimanne El-Zein, Katerina Bendak, PhD, Cara E Toscan, PhD, Chelsea Mayoh, Stephen W Erickson, PhD, Beverly A Teicher, PhD, Malcolm A Smith, MD PhD

Blood (2019) 134 (Supplement_1): 3875.

https://doi.org/10.1182/blood-2019-123867

Published: 2019

Journal Articles

Functional Defects In Neutrophils Derived From Ezh2 Null Mice

Albert Perez-Ladaga, PhD, Bennett Caughey, Huafeng Xie, PhD, Stuart H. Orkin, MD, David B. Sykes, MD, PhD, Benjamin L. Ebert, MD, PhD, Rafael Bejar, MD, PhD

Blood (2013) 122 (21): 1556.

https://doi.org/10.1182/blood.V122.21.1556.1556

Published: 2013

Journal Articles

Evaluation Of Multidrug Resistance (MDR) Functional Activity and Expression Levels Of P-Glycoprotein and MDR Related Protein-1 For The Prediction Of Treatment Failure In Chronic Myeloid Leukemia Patients

Sang Hyuk Park, MD, Chan-Jeoung Park, MD, PhD, Dae-Young Kim, Bo-Ra Lee, Young Jin Kim, Young-Uk Cho, Seongsoo Jang, MD, PhD, Hyun-Sook Chi

Blood (2013) 122 (21): 2600.

https://doi.org/10.1182/blood.V122.21.2600.2600

Published: 2013

Journal Articles

Statins Increase Antileukemic Potency of Imatinib Through the Inhibition of MDR/ABCB1 and BCRP/ABCG2 Drug Transporters Activity

Eliza Glodkowska-Mrowka, MD, Piotr Mrowka, M.Sc., Magdalena Winiarska, PhD, Grzegorz Basak, MD, PhD, Joanna Niesiobedzka-Krezel, MD, Ilona Seferynska, MD, PhD, Pawel Krzysztof Wlodarski, MD, PhD, Marek Jakobisiak, MD, PhD, Tomasz Stoklosa, MD, PhD

Blood (2011) 118 (21): 2742.

https://doi.org/10.1182/blood.V118.21.2742.2742

Published: 2011

Journal Articles

Secondary Acute Myeloid Leukemia (AML), Including Therapy-Related AML, Associates with Worse Treatment Outcomes, Than De Novo AML Even After Hematopoietic Stem Cell Transplantation, and Its Unfavorable Behavior Does Not Associated with Functional Activity of p-Glycoprotein, MDR1

Boram Han, Ha Yeon Lee, Jun Ho Yi, Jun Ho Jang, Kihyun Kim, Hee Jin Kim, Sun-Hee Kim, Chul Won Jung, Dong Hwan (Dennis) Kim

Blood (2010) 116 (21): 2157.

https://doi.org/10.1182/blood.V116.21.2157.2157

Published: 2010

Journal Articles

Erlotinib Inhibits ABC Transporters of AML Progenitors with Stem Cell Features and Increases Chemosensitivity to Current AML Drugs

Marie Sebert, Elodie Lainey, Sylvain Thepot, Maximilien Tailler, Lionel Ades, Claude Gardin, Pierre Fenaux, MD, PhD, Guido Kroemer, Simone Boehrer

Blood (2010) 116 (21): 2163.

https://doi.org/10.1182/blood.V116.21.2163.2163

Published: 2010

Journal Articles

Chemotherapy-Resistant T Cells

Cameron J. Turtle, MBBS, PhD

Blood (2010) 116 (21): SCI-51.

https://doi.org/10.1182/blood.V116.21.SCI-51.SCI-51

Published: 2010

Journal Articles

In Vitro and In Vivo Inhibition of P-Glycoprotein (ABCB1) by a Novel Non-Substrate Compound: HG-829

Gisela Caceres, Ph.D., Robert W Robey, Ph.D., Lubomir Sokol, MD, PhD, Kathy Rocha McGraw, William J Fulp, Justine Clark, MS, Nicholas J Lawrence, Ph.D., Said Sebti, Ph.D., Susan E. Bates, MD, Alan F. List

Blood (2010) 116 (21): 3986.

https://doi.org/10.1182/blood.V116.21.3986.3986

Published: 2010

Journal Articles

Selective Depletion of T Cell Alloresponses Using a Photodepletion Strategy Preferentially Targets CD4+ T Cells.

Zachariah A. McIver, DO, Andrew Grim, BS, Nicolas Naguib, BS, Hahn Khuu, Minoo Battiwalla, MD, MS, David Stroncek, MD, A. John Barrett, MD

Blood (2010) 116 (21): 1467.

https://doi.org/10.1182/blood.V116.21.1467.1467

Published: 2010

Journal Articles

Stem-Like Tumor Cells Confer Drug Resistant Properties to Mantle Cell Lymphoma

Hyun Joo Jung, MD, Nami McCarty, PhD

Blood (2010) 116 (21): 1840.

https://doi.org/10.1182/blood.V116.21.1840.1840

Published: 2010

Journal Articles

Anti-Leukemic Activity of Mitochondrially-Directed Asymmetrical 2-2'-Binaphthoquinones.

Rebecca Ricklis, MSc, Milena Vuica-Ross, MD, Robert Brodsky, MD, Ed Sausville, MD, PhD, Chi Van Dang, MD, PhD, Judith E Karp, MD, Ashkan Emadi, MD, PhD

Blood (2009) 114 (22): 4799.

https://doi.org/10.1182/blood.V114.22.4799.4799

Published: 2009

Journal Articles

Mechanisms of Discrepancy Between CD33 Expression and Gemtuzumab Ozogamicin-Induced Cytotoxicity in Leukemia Cells.

Yasushi Takamatsu, MD, Shiro Jimi, PhD, Nanako Toyota, Shuuji Hara, PhD, Yuka Yoshimura, Junji Suzumiya, MD, Kazuo Tamura, MD

Blood (2009) 114 (22): 4812.

https://doi.org/10.1182/blood.V114.22.4812.4812

Published: 2009

Journal Articles

Monosomy Karyotype in Acute Myeloid Leukemia Predicts Adverse Treatment Outcome with Low Complete Remission Rate and Worse Event-Free and Overall Survival, and Associates with High Functional Activity of Multidrug Resistance (MDR).

Hee Kyung Ahn, Dong Hwan (Dennis) Kim, Silvia Park, Jun Ho Jang, Kihyun Kim, Hee-Jin Kim, Sun-Hee Kim, Chul Won Jung

Blood (2009) 114 (22): 3112.

https://doi.org/10.1182/blood.V114.22.3112.3112

Published: 2009

Journal Articles

The Investigation of Mechanisms Underlying Hoechst 33342 Efflux in Myeloma ‘Side Population' Cells.

Yen Siew Loh, PhD, John D Allen, PhD, Ammira Al-shabeeb, PhD, Ross D. Brown, PhD, MBA, Jia Li, Joshua Douglas, Professor, Daniel Sze, A/Professor

Blood (2009) 114 (22): 2759.

https://doi.org/10.1182/blood.V114.22.2759.2759

Published: 2009

Journal Articles

MDR1 gene Polymorphisms Are Related to Efflux-Independent P-Glycoprotein Overexpression in Brazilian AML Patients

Marcos Antonio Mauricio Scheiner, Sr., MSc, Pharmacist, Flavia da Cunha Vasconcelos, PhD, Student, Raquel Ciuvalschi Maia, Sr., MD, PhD

Blood (2008) 112 (11): 5049.

https://doi.org/10.1182/blood.V112.11.5049.5049

Published: 2008

Journal Articles

Reduced Effect of Inotuzumab Ozogamicin (CMC544) on P-Glycoprotein Positive Malignant B Cells and Its Restoration by Multidrug Resistance Modifiers.

Akihiro Takeshita, PhD, MD, Kaori Shinjo, PhD, MD, Nozomi Yamakage, MA, Takaaki Ono, MD, Isao Hirano, MD, Kenji Okinaka, MD, Hirotaka Matsui, PhD, MD, Satoki Nakamura, MD, Kazuyuki Shigeno, MD, Masato Maekawa, PhD, MD, Kazunori Ohnishi, PhD, MD, Ryuzo Ohno, PhD, MD

Blood (2007) 110 (11): 2378.

https://doi.org/10.1182/blood.V110.11.2378.2378

Published: 2007

Journal Articles

Amonafide L-Malate Bypasses Multidrug Resistance Proteins in Secondary Acute Myeloid Leukemia.

Kieran L. O’Loughlin, BS, Hans Minderman, PhD, Laurie A. Ford, BS, Maria R. Baer, MD

Blood (2007) 110 (11): 2380.

https://doi.org/10.1182/blood.V110.11.2380.2380

Published: 2007

Journal Articles

C3435T Polymorphism of MDR1 Gene Is Not Associated with p-Glycoprotein Function of Leukemic Blasts and Clinical Outcomes in Patients with Acute Myeloid Leukemia.

Michael Jinpyo Lee, Eun-Hye Hur, MS, Je-Hwan Lee, MD, Seong-Jun Choi, MD, Jung-Hee Lee, MD, Miee Seol, RN, Keun-Hee Kim, RN, Hee-Jung Lee, RN, Ip-Sol Kang, RN, Kyung-Soo Shim, RN, Seong-Gil Ryu, RPh, Young-Ah Kang, RN, Young-Shin Lee, RN, Chan-Jeoung Park, MD, Hyung-Sook Chi, MD, Kyoo-Hyung Lee, MD

Blood (2007) 110 (11): 2381.

https://doi.org/10.1182/blood.V110.11.2381.2381

Published: 2007

Journal Articles

Assessment of Multidrug Resistance and FLT3 Internal Tandem Duplication in Patients with Plasmacytoid Dendritic Cell Leukemia.

Alex F. Sandes, MD, Rodrigo S. Barroso, MD, Eliza Y.S. Kimura, Mihoko Yamamoto, MD, PhD

Blood (2007) 110 (11): 4251.

https://doi.org/10.1182/blood.V110.11.4251.4251

Published: 2007

Journal Articles

MDR-1 Gene and BCRP Are Involved in the Resistance to Imatinib in K-562 Cell Line.

Mabel Lardo, Patricia Gargallo, Michele Bianchini, Graciela Lucero, Benjamin Koziner, Irene Larripa, Alberto Lazarowski

Blood (2006) 108 (11): 4391.

https://doi.org/10.1182/blood.V108.11.4391.4391

Published: 2006

NARROW

Pediatric Preclinical Testing Consortium Evaluation of the Novel Anti-Microtubule Drug E7130 in Xenograft Models of Early T-Cell Precursor Acute Lymphoblastic Leukemia

Functional Defects In Neutrophils Derived From Ezh2 Null Mice

Evaluation Of Multidrug Resistance (MDR) Functional Activity and Expression Levels Of P-Glycoprotein and MDR Related Protein-1 For The Prediction Of Treatment Failure In Chronic Myeloid Leukemia Patients

Statins Increase Antileukemic Potency of Imatinib Through the Inhibition of MDR/ABCB1 and BCRP/ABCG2 Drug Transporters Activity

Secondary Acute Myeloid Leukemia (AML), Including Therapy-Related AML, Associates with Worse Treatment Outcomes, Than De Novo AML Even After Hematopoietic Stem Cell Transplantation, and Its Unfavorable Behavior Does Not Associated with Functional Activity of p-Glycoprotein, MDR1

Erlotinib Inhibits ABC Transporters of AML Progenitors with Stem Cell Features and Increases Chemosensitivity to Current AML Drugs

Chemotherapy-Resistant T Cells

In Vitro and In Vivo Inhibition of P-Glycoprotein (ABCB1) by a Novel Non-Substrate Compound: HG-829

Selective Depletion of T Cell Alloresponses Using a Photodepletion Strategy Preferentially Targets CD4+ T Cells.

Stem-Like Tumor Cells Confer Drug Resistant Properties to Mantle Cell Lymphoma

Anti-Leukemic Activity of Mitochondrially-Directed Asymmetrical 2-2'-Binaphthoquinones.

Mechanisms of Discrepancy Between CD33 Expression and Gemtuzumab Ozogamicin-Induced Cytotoxicity in Leukemia Cells.

Monosomy Karyotype in Acute Myeloid Leukemia Predicts Adverse Treatment Outcome with Low Complete Remission Rate and Worse Event-Free and Overall Survival, and Associates with High Functional Activity of Multidrug Resistance (MDR).

The Investigation of Mechanisms Underlying Hoechst 33342 Efflux in Myeloma ‘Side Population' Cells.

MDR1 gene Polymorphisms Are Related to Efflux-Independent P-Glycoprotein Overexpression in Brazilian AML Patients

Reduced Effect of Inotuzumab Ozogamicin (CMC544) on P-Glycoprotein Positive Malignant B Cells and Its Restoration by Multidrug Resistance Modifiers.

Amonafide L-Malate Bypasses Multidrug Resistance Proteins in Secondary Acute Myeloid Leukemia.

C3435T Polymorphism of MDR1 Gene Is Not Associated with p-Glycoprotein Function of Leukemic Blasts and Clinical Outcomes in Patients with Acute Myeloid Leukemia.

Assessment of Multidrug Resistance and FLT3 Internal Tandem Duplication in Patients with Plasmacytoid Dendritic Cell Leukemia.

MDR-1 Gene and BCRP Are Involved in the Resistance to Imatinib in K-562 Cell Line.

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American Society of Hematology

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