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Journal Articles

DOT1L as a therapeutic target for the treatment of DNMT3A -mutant acute myeloid leukemia

Rachel E. Rau, Benjamin A. Rodriguez, Min Luo, Mira Jeong, Allison Rosen, Jason H. Rogers, Carly T. Campbell, Scott R. Daigle, Lishing Deng, Yongcheng Song, Steve Sweet, Timothy Chevassut, Michael Andreeff, Steven M. Kornblau, Wei Li, Margaret A. Goodell

Blood (2016) 128 (7): 971–981.

https://doi.org/10.1182/blood-2015-11-684225

Published: 2016

Includes: Supplemental data

Journal Articles

First Preclinical Report of the Efficacy and PD Results of KHK2823, a Non-Fucosylated Fully Human Monoclonal Antibody Against IL-3Rα

Tadakazu Akiyama, PhD, Shin-ichiro Takayanagi, PhD, Yoshimi Maekawa, Kohta Miyawaki, MD, Fumiaki Jinnouchi, MD, Takashi Jiromaru, MD, Takeshi Sugio, MD, Shinya Daitoku, MD, Hirotake Kusumoto, MD, Munetake Shimabe, PhD, Satoshi Nishikawa, Kengo Yamawaki, Kousuke Iijima, Masanori Hiura, Takeshi Takahashi, PhD, Yoshikane Kikushige, MD PhD, Hiromi Iwasaki, MD PhD, Koichi Akashi, MD PhD, Tomonori Tawara, PhD

Blood (2015) 126 (23): 1349.

https://doi.org/10.1182/blood.V126.23.1349.1349

Published: 2015

Journal Articles

Preclinical Characterization of a Potent, Selective Inhibitor of the Protein Methyltransferase DOT1L for Use in the Treatment of MLL -Rearranged Leukemia.

Roy M Pollock, PhD, Scott R Daigle, Carly A Therkelsen, Aravind Basavapathruni, PhD, Lei Jin, PhD, Christina J Allain, Christine R Klaus, Alejandra Raimondi, PhD, Margaret Porter Scott, PhD, Richard Chesworth, DPhil, Mikel P Moyer, PhD, Robert A Copeland, PhD, Victoria M Richon, PhD, Edward J Olhava, PhD

Blood (2012) 120 (21): 2379.

https://doi.org/10.1182/blood.V120.21.2379.2379

Published: 2012

Journal Articles

Enhanced Delivery of Rituximab In Combination with Methotrexate-Based Blood-Brain Barrier Disruption for Patients with Newly Diagnosed Primary CNS Lymphoma.

Nancy D. Doolittle, Dale F. Kraemer, Cynthia Lacy, Rose Marie Tyson, Edward A. Neuwelt

Blood (2010) 116 (21): 2792.

https://doi.org/10.1182/blood.V116.21.2792.2792

Published: 2010

Journal Articles

Treatment Model of CNS Lymphoma Using Complement-Dependent Cytotoxicity Induced by Rituximab and Autoserum.

Yasuyuki Miyake, Yasushi Okoshi, Takayuki Machino, Shigeru Chiba

Blood (2009) 114 (22): 3739.

https://doi.org/10.1182/blood.V114.22.3739.3739

Published: 2009

Journal Articles

Methotrexate and/or Rituximab in a New Nude Rat Central Nervous System Lymphoma Model: Efficacy, Toxicity and Magnetic Resonance Imaging.

Kristoph Jahnke, MD, Leslie L. Muldoon, PhD, Csanad G. Varallyay, MD, Seth J. Lewin, BS, Robert D. Brown, Dale F. Kraemer, PhD, Carole Soussain, MD, Edward A. Neuwelt, MD

Blood (2007) 110 (11): 4515.

https://doi.org/10.1182/blood.V110.11.4515.4515

Published: 2007

Journal Articles

Characterization of a Bone Marrow Derived Mesenchymal Cell Line from Nude Rat Assembling Tumor Stem/Progenitor Cell Properties In Vitro and In Vivo.

Mengyu Wang, MD, Jingfang Ju, Ph.D, Stein Saeboe-Larssen, Ph.D, Svein-Ole Mikalsen, Ph.D, Elena Olsen, Jahn M. Nesland, MD, Ph.D, Oystein Fodstad, MD, Ph.D, Gunhild Maelandsmo, Ph.D, Gunnar Kvalheim, MD, PhD

Blood (2006) 108 (11): 4256.

https://doi.org/10.1182/blood.V108.11.4256.4256

Published: 2006

Journal Articles

Adult Human Blood Leukocytes as a Source of Tissue-Committed Progenitors for Cellular Therapy of Cardiovascular Disease.

Yael Porat, PhD, Valetin Fulga, MD, Danny Belkin, PhD, Daphna Shimoni, MSc, Adina Belleli, PhD, David Czeiger, MD, Damras Tresukosol, MD, Suphachai Chaithiraphan, MD, Alexander Battler, MD

Blood (2005) 106 (11): 32.

https://doi.org/10.1182/blood.V106.11.32.32

Published: 2005

Journal Articles

Human Endothelial Cells Generated In Vitro from Circulating Progenitors Represent a Safe Tool for Targeting of Myocardial Tissue.

Ruth Koeck, Dominik G.F. Wolf, MD, Holger F. Rumpold, MD, Harald Ott, MD, Gerold Untergasser, MD, Martin Erdel, PhD, Paul Debagge, MD, Guenther A. Gastl, MD, Eberhard Gunslius, MD

Blood (2004) 104 (11): 4138.

https://doi.org/10.1182/blood.V104.11.4138.4138

Published: 2004

Journal Articles

Bone Marrow Stroma-Derived Mesenchymal Cell Cultures from Nude/Nude Rat Showing Both Ex Vivo Differentiation Properties and High Metastatic Potential in Nude Mice.

Mengyu Wang, MD, Gunnar Kvalheim, MD, Ph.D, Svein-Ole Mikalsen, Ph.D, Jahn M. Nesland, MD, Ph.D, Gunhild Mælandsmo, Ph.D, Øystein Fodstad, MD, Ph.D

Blood (2004) 104 (11): 4262.

https://doi.org/10.1182/blood.V104.11.4262.4262

Published: 2004

Journal Articles

Human Stem Cells Armed with Bispecific Antibodies Home to Injury-Specific Molecules in Myocardial Infarcts in Nude Rats.

Lawrence G. Lum, MD, DSc, Pamela A. Davol, MEd, Richard E. Sievers, Ryan C. Grabert, Qizhi Fang, MD, Jonathan M. Gall, Michael S. Yee, James W. Larrick, MD, PhD, Randall J. Lee, MD, PhD

Blood (2004) 104 (11): 2697.

https://doi.org/10.1182/blood.V104.11.2697.2697

Published: 2004

Journal Articles

Ex-Vivo Expanded Human Bone Marrow-Derived AC133+ Cells To Treat Myocardial Infarction.

Frida Grynspan, Ph.D., Moshe Marikovsky, Ph.D., Efrat Landau, M.Sc., Tony Peled, Arnon Nagler, MD, Radka Holbova, Victor Guetta, MD, Shmuel Fuchs, MD, Shimon Feinberg, MD, Jonathan Leor, MD

Blood (2004) 104 (11): 154.

https://doi.org/10.1182/blood.V104.11.154.154

Published: 2004

NARROW

DOT1L as a therapeutic target for the treatment of DNMT3A -mutant acute myeloid leukemia

First Preclinical Report of the Efficacy and PD Results of KHK2823, a Non-Fucosylated Fully Human Monoclonal Antibody Against IL-3Rα

Preclinical Characterization of a Potent, Selective Inhibitor of the Protein Methyltransferase DOT1L for Use in the Treatment of MLL -Rearranged Leukemia.

Enhanced Delivery of Rituximab In Combination with Methotrexate-Based Blood-Brain Barrier Disruption for Patients with Newly Diagnosed Primary CNS Lymphoma.

Treatment Model of CNS Lymphoma Using Complement-Dependent Cytotoxicity Induced by Rituximab and Autoserum.

Methotrexate and/or Rituximab in a New Nude Rat Central Nervous System Lymphoma Model: Efficacy, Toxicity and Magnetic Resonance Imaging.

Characterization of a Bone Marrow Derived Mesenchymal Cell Line from Nude Rat Assembling Tumor Stem/Progenitor Cell Properties In Vitro and In Vivo.

Adult Human Blood Leukocytes as a Source of Tissue-Committed Progenitors for Cellular Therapy of Cardiovascular Disease.

Human Endothelial Cells Generated In Vitro from Circulating Progenitors Represent a Safe Tool for Targeting of Myocardial Tissue.

Bone Marrow Stroma-Derived Mesenchymal Cell Cultures from Nude/Nude Rat Showing Both Ex Vivo Differentiation Properties and High Metastatic Potential in Nude Mice.

Human Stem Cells Armed with Bispecific Antibodies Home to Injury-Specific Molecules in Myocardial Infarcts in Nude Rats.

Ex-Vivo Expanded Human Bone Marrow-Derived AC133+ Cells To Treat Myocardial Infarction.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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