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Journal Articles

Deletion of the Tumor Suppressor Gene NF1 Is An Alternative Mechanism for Aberrant Activation of the RAS Pathway and Is Found in 11% of Acute Myeloid Leukemia.

Claudia Haferlach, MD, Alexander Kohlmann, PhD, Sonja Schindela, Wolfgang Kern, Susanne Schnittger, PhD, Torsten Haferlach, MD

Blood (2009) 114 (22): 401.

https://doi.org/10.1182/blood.V114.22.401.401

Published: 2009

Journal Articles

Imatinib Mesylate Reduces Plexiform Neurofibromas by Targeting the Hematopoietic Microenvironment.

Feng-Chun Yang, MD, PhD, David Ingram, M.D., Shi Chen, M.D., Ph.D., Kent Robertson, M.D., Ph.D., Xiohong Li, Jin Yuan, Scott Knoll, Whitney Horn, Gary Hutchins, M.D., Ph.D., L. Parada, Ph.D., David Wade Clapp, M.D.

Blood (2007) 110 (11): 1915.

https://doi.org/10.1182/blood.V110.11.1915.1915

Published: 2007

Journal Articles

Genetic Disruption of Rac1 but Not Rac2 Is Sufficient To Ameliorate the Development of Juvenile Myeloproliferative Myeloid Leukemia in Nf1 − / − Mice.

Fengchun Yang, MD, PhD, Jayme Allen, MD, Shi Chen, MD, Yan Li, Jin Yuan, Waylan Bessler, David A. Ingram, MD, D. Wade Clapp, MD

Blood (2006) 108 (11): 3612.

https://doi.org/10.1182/blood.V108.11.3612.3612

Published: 2006

Journal Articles

Discrepancies in p21ras, p53, and Mdm2 Protein Expression Predict Worse Prognosis in Acute Myeloid Leukemia.

Elizabeth Schulz, MD, MS, Irene Lorand-Metze, MD;PhD, Rainer Koch, PhD, Solange Campelo Costa, MD;MS, Fernando Ferreira Costa, MD; PhD, Sara Terezinha Olalla Saad, MD; PhD

Blood (2005) 106 (11): 4521.

https://doi.org/10.1182/blood.V106.11.4521.4521

Published: 2005

Journal Articles

Loss of p21ras, p53, and Mdm2 Protein Expression Is Indicative of Worse Prognosis in Myelodysplastic Syndromes.

Elizabeth Schulz, MD;MS, Irene Lorand-Metze, MD;PhD, Rainer Koch, PhD, Solange C. Costa, MD;MS, Fernando F. Costa, MD;PhD, Sara T.O. Saad, MD;PhD

Blood (2004) 104 (11): 3433.

https://doi.org/10.1182/blood.V104.11.3433.3433

Published: 2004

Journal Articles

Functional Analysis of Leukemia-Associated PTPN11 Mutations in Primary Hematopoietic Cells.

Suzanne Schubbert, Kenneth Lieuw, Sara L. Rowe, Connie M. Lee, XiaXin Li, Mignon Loh, D. Wade Clapp, Kevin Shannon

Blood (2004) 104 (11): 2423.

https://doi.org/10.1182/blood.V104.11.2423.2423

Published: 2004

Journal Articles

Nf1 Plays an Essential Role in Osteoclasts Development Via Hyperactivation of Ras- PI3K Signaling.

Shi Chen, David A. Ingram, M.D., Mary Jo Wenning, Janet Hock, M.D., Feng-Chun Yang, M.D., D. Wade Clapp, M.D.

Blood (2004) 104 (11): 1462.

https://doi.org/10.1182/blood.V104.11.1462.1462

Published: 2004

Journal Articles

Murine and Human NF1 Haploinsufficient Mast Cells Promote Alterations in Fibroblast Function and Organization of the Extracellular Matrix in Three-Dimensional Collagen Lattices and this Gain in Function Is Abrogated by the Addition of STI-571.

Fengchun Yang, M.D., Clegg Travis, Shi Chen, Xiaohong Li, Selina A. Estwick, Jin Yuan, David A. Ingram, M.D., D. Wade Clapp, M.D.

Blood (2004) 104 (11): 1465.

https://doi.org/10.1182/blood.V104.11.1465.1465

Published: 2004

Journal Articles

Phosphatidylinositol-3 kinase regulates p21ras activation during IgE-mediated stimulation of human basophils

Katsushi Miura, Donald W. MacGlashan, Jr

Blood (2000) 96 (6): 2199–2205.

https://doi.org/10.1182/blood.V96.6.2199

Published: 2000

Journal Articles

Analysis of Signal Transduction Pathways in Human Eosinophils Activated by Chemoattractants and the T-Helper 2–Derived Cytokines Interleukin-4 and Interleukin-5

Paul J. Coffer, René C. Schweizer, Gerald R. Dubois, Tjander Maikoe, Jan-Willem J. Lammers, Leo Koenderman

Blood (1998) 91 (7): 2547–2557.

https://doi.org/10.1182/blood.V91.7.2547

Published: 1998

Journal Articles

Proliferation Signaling and Activation of Shc, p21Ras, and Myc Via Tyrosine 764 of Human Granulocyte Colony-Stimulating Factor Receptor

John P. de Koning, Amrita A. Soede-Bobok, Anita M. Schelen, Louise Smith, Daphne van Leeuwen, Valeria Santini, Boudewijn M.T. Burgering, Johannes L. Bos, Bob Löwenberg, Ivo P. Touw

Blood (1998) 91 (6): 1924–1933.

https://doi.org/10.1182/blood.V91.6.1924

Published: 1998

NARROW

Deletion of the Tumor Suppressor Gene NF1 Is An Alternative Mechanism for Aberrant Activation of the RAS Pathway and Is Found in 11% of Acute Myeloid Leukemia.

Imatinib Mesylate Reduces Plexiform Neurofibromas by Targeting the Hematopoietic Microenvironment.

Genetic Disruption of Rac1 but Not Rac2 Is Sufficient To Ameliorate the Development of Juvenile Myeloproliferative Myeloid Leukemia in Nf1 − / − Mice.

Discrepancies in p21ras, p53, and Mdm2 Protein Expression Predict Worse Prognosis in Acute Myeloid Leukemia.

Loss of p21ras, p53, and Mdm2 Protein Expression Is Indicative of Worse Prognosis in Myelodysplastic Syndromes.

Functional Analysis of Leukemia-Associated PTPN11 Mutations in Primary Hematopoietic Cells.

Nf1 Plays an Essential Role in Osteoclasts Development Via Hyperactivation of Ras- PI3K Signaling.

Murine and Human NF1 Haploinsufficient Mast Cells Promote Alterations in Fibroblast Function and Organization of the Extracellular Matrix in Three-Dimensional Collagen Lattices and this Gain in Function Is Abrogated by the Addition of STI-571.

Phosphatidylinositol-3 kinase regulates p21ras activation during IgE-mediated stimulation of human basophils

Analysis of Signal Transduction Pathways in Human Eosinophils Activated by Chemoattractants and the T-Helper 2–Derived Cytokines Interleukin-4 and Interleukin-5

Proliferation Signaling and Activation of Shc, p21Ras, and Myc Via Tyrosine 764 of Human Granulocyte Colony-Stimulating Factor Receptor

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American Society of Hematology

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American Society of Hematology

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