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Journal Articles

Shared and Distinctive Ultrastructural Abnormalities Expressed By Megakaryocytes in Bone Marrow and Spleen from Patients with Primary Myelofibrosis

Maria Zingariello, PhD, Vittorio Rosti, MD, Alessandro M. Vannucchi, MD, Paola Guglielmelli, MD PhD, Claudio Bardelli, PhD, Maria Mazzarini, Rosa Alba Rana, Giovanni Barosi, Anna Rita Rita Migliaccio, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4209.
https://doi.org/10.1182/blood-2019-123140
Published: 2019
Journal Articles

Calreticulin Ins5 and Del52 Mutations Impair Unfolded Protein and Oxidative Stress Responses in Hematopoietic Cells

Simona Salati, PhD, Elena Genovese, BSc, Zelia Prudente, BSc, PhD, Chiara Carretta, Niccolò Bartalucci, PhD BSc, Valentina Pennucci, PhD, Samantha Ruberti, BSc, PhD, Chiara Rossi, PharmD, Sebastiano Rontauroli, BSc, Carmela Mannarelli, PhD, Roberta Zini, BSc, PhD, Elisa Bianchi, BSc, PhD, Paola Guglielmelli, MD PhD, Enrico Tagliafico, MDPhD, Alessandro M. Vannucchi, MD, Rossella Manfredini, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4332.
https://doi.org/10.1182/blood-2018-99-112550
Published: 2018
Journal Articles

High Glutathione and NAD(P)H Levels, and Increased Protein Folding Capacity Are Involved in Mediating Proteasome Inhibitor-Resistance in Multiple Myeloma

Lenka Besse, Andrej Besse, Marianne Kraus, Jürgen Bader, Christoph Driessen, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1258.
https://doi.org/10.1182/blood.V130.Suppl_1.1258.1258
Published: 2017
Journal Articles

Systematic Assessment of GATA2 Genetic Variation Reveals the Presence of Novel Disease-Causing Synonymous Exonic Mutations

Emilia J Kozyra, Victor Pastor Loyola, MSc, Claudia Wehr, Sushree Sangita Sahoo, M.Sc., Rebecca Voss, Enikoe Amina Szvetnik, Shinsuke Hirabayashi, MD, Albert Catala, Henrik Hasle, MD PhD, Marry M. Van den Heuvel-Eibrink, MD, Krisztián Kallay, MD, Riccardo Masetti, MDPhD, Barbara De Moerloose, MD PhD, Markus Schmugge, MD, Owen Smith, MD, Marek Ussowicz, Jan Stary, Ester Mejstrikova, Ramunė Pasaulienė, Irith Baumann, Dr. MD, Gudrun Göhring, MD, Brigitte Schlegelberger, Prof. Dr., Ulrich Salzer, Michael Lübbert, Eirini Trompouki, PhD, Charlotte M. Niemeyer, MD, Marcin W. Wlodarski, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2449.
https://doi.org/10.1182/blood.V130.Suppl_1.2449.2449
Published: 2017
Journal Articles

Developmental Compound E61 Overcomes Proteasome Inhibitor Resistance in Multiple Myeloma Cells By Targeting the Cellular Protein Folding Machinery

Reeder McNeil Robinson, PhD, Leticia Reyes, Ravyn M. Thompson, Yefim Manevich, Jesse McClure, Matthew Champion, PhD, James Chou, Nathan G. Dolloff, PhD
Journal: Blood
Blood (2016) 128 (22): 1139.
https://doi.org/10.1182/blood.V128.22.1139.1139
Published: 2016
Journal Articles

The Novel Sulfonamidebenzamide ML291 Activates Apoptotic UPR Signaling in Pediatric Leukemia

Danielle Garshott, Nicole Melong, MSc, Tania T. Sarker, MD MPH, Yue Xi, PhD, Amy Brownell, Michael Callaghan, MD, Jason N. Berman, MD, Andrew Fribley, PhD
Journal: Blood
Blood (2016) 128 (22): 3523.
https://doi.org/10.1182/blood.V128.22.3523.3523
Published: 2016
Journal Articles

The Hunt for the "Minimal" Structure of a Functional ADAMTS13: Study of Deletion Mutations of ADAMTS13 By Small-Angle X-Ray Scattering

Jian Zhu, PhD, Joshua Muia, PhD, Louis Deforche, PhD, Karen Vanhoorelbeke, PhD, Niraj H. Tolia, PhD, J. Evan Sadler, MD PhD
Journal: Blood
Blood (2016) 128 (22): 254.
https://doi.org/10.1182/blood.V128.22.254.254
Published: 2016
Journal Articles

Proteasome Inhibitor-Adapted Myeloma Cells That Lack Proteasome Gene Mutations Resist Highly Efficient Proteasome Inhibition and Show Proteomic Alterations That Suggest Complex Metabolic Changes

Lenka Besse, PhD, Guillem Soriano, Nan Li, Andrej Besse, Marianne Kraus, Juergen Bader, Tobias Christian Silzle, MD, Nico Meeuwenoord, Hans den Dulk, Herman S Overkleeft, Bogdan Florea, Christoph Driessen, MD
Journal: Blood
Blood (2015) 126 (23): 1278.
https://doi.org/10.1182/blood.V126.23.1278.1278
Published: 2015
Journal Articles

Heatshock Protein (HSP) Family Expression Is Dichotomous and Prognostic in Acute Myelogenous Leukemia (AML)

Steven M. Kornblau, MD, Chenyue W Hu, Yihua Qiu, MD, Suk Young Yoo, PhD, Trang T Nguyen, Tapan Kadia, MD, Gautam Borthakur, MD, Kevin Coombes, PhD, Amina A Qutub, PhD
Journal: Blood
Blood (2014) 124 (21): 1026.
https://doi.org/10.1182/blood.V124.21.1026.1026
Published: 2014
Journal Articles

Cereblon Binding IMiD Small Molecules Mediate Myeloma Cell Death Via IRF4

Yuan Xiao Zhu, Ph.D., Chang-Xin Shi, Ph.D., Laura Bruins, Klaus Martin Kortuem, MD, Jessica Schmidt, Xiu-Bao Chang, Ph.D., Esteban Braggio, Ph.D., Leif Bergsagel, M.D., Keith Stewart, MBA, MB, CHB
Journal: Blood
Blood (2012) 120 (21): 1807.
https://doi.org/10.1182/blood.V120.21.1807.1807
Published: 2012
Journal Articles

Differential Engagement of the Unfolded Protein Response by Human and Porcine Factor VIII

Harrison C. Brown, BBA, Bagirath Gangadharan, MS, Christopher Doering, PhD
Journal: Blood
Blood (2010) 116 (21): 2224.
https://doi.org/10.1182/blood.V116.21.2224.2224
Published: 2010
Journal Articles

Novel Compound Heterozygous Factor V Deficiency with Severe Clinical Phenotype.

Kimberley Talbot, MPhil, Jina Song, PhD, Lily Eghdami, BSc, Jeff Hewitt, PhD, Cedric J. Carter, MD, Ross T.A. MacGillivray, PhD, Ed L.G. Pryzdial, PhD
Journal: Blood
Blood (2009) 114 (22): 3490.
https://doi.org/10.1182/blood.V114.22.3490.3490
Published: 2009
Journal Articles

Response: Cautious interpretation of assessment of AID variant activities using cells with endogenous AID expression

Xiaosheng Wu, Diane F. Jelinek
Journal: Blood
Blood (2009) 113 (8): 1864.
https://doi.org/10.1182/blood-2008-11-187732
Published: 2009
Journal Articles

The Role of N-Linked Glycosylation in Expression and Function of ADAMTS13

Agata Nowak, Chan Kwo Chion, Michael Laffan, Thomas A J McKinnon
Journal: Blood
Blood (2008) 112 (11): 3086.
https://doi.org/10.1182/blood.V112.11.3086.3086
Published: 2008
Journal Articles

Characterization of 14-3-3β Expression during Differentiation of the Megakaryocytic Cell Line MEG-01

Chutima Kumkhaek, PhD, Wenli Liu, MD, Wulin Aerbajinai, MD, Ph.D, Jianqiong Zhu, MD, Suthat Fucharoen, MD, Griffin P Rodgers, MD
Journal: Blood
Blood (2008) 112 (11): 4733.
https://doi.org/10.1182/blood.V112.11.4733.4733
Published: 2008
Journal Articles

Genomic and Proteomic Signatures of Human Mesenchymal Stem Cells.

Wolfgang Wagner, MD, Robert E. Feldmann, PhD, Frederik Wein, Anja Seckinger, Ulf Krause, MD, Maria Frankhauser, PhD, Martin H. Maurer, MD, Jonathon Blake, PhD, Volker Eckstein, PhD, Rainer Saffrich, PhD, Patrick Wuchter, MD, Wolfgang Kuschinsky, MD, Anthony D. Ho, MD
Journal: Blood
Blood (2005) 106 (11): 2300.
https://doi.org/10.1182/blood.V106.11.2300.2300
Published: 2005
Journal Articles

Global Gene Expression Analysis Demonstrates that Transforming Growth Factor β1 (TGF-β1) Signals Exclusively through Receptor Complexes Involving TGF-β Receptor I and Identifies Numerous Targets of TGF-β Signaling.

Goran Karlsson, Yingchun Liu, Marie-José Goumans, Jonas Larsson, Ju-Seog Lee, Snorri S. Thorgeirsson, Markus Ringnér, Stefan Karlsson
Journal: Blood
Blood (2004) 104 (11): 2178.
https://doi.org/10.1182/blood.V104.11.2178.2178
Published: 2004