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Journal Articles

Plasminogen: an enigmatic zymogen

Charithani B. Keragala, Robert L. Medcalf

Blood (2021) 137 (21): 2881–2889.

https://doi.org/10.1182/blood.2020008951

Published: 2021

Journal Articles

Reduced expression of annexin A2 is associated with impaired cell surface fibrinolysis and venous thromboembolism

Hannah Fassel, Huigen Chen, Mary Ruisi, Neha Kumar, Maria DeSancho, Katherine A. Hajjar

Blood (2021) 137 (16): 2221–2230.

https://doi.org/10.1182/blood.2020008123

Published: 2021

Includes: Supplemental data

Journal Articles

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Adam Miszta, Anna K. Kopec, Asmita Pant, Lori A. Holle, James R. Byrnes, Daniel A. Lawrence, Kirk C. Hansen, Matthew J. Flick, James P. Luyendyk, Bas de Laat, Alisa S. Wolberg

Blood (2020) 135 (19): 1704–1717.

https://doi.org/10.1182/blood.2019004267

Published: 2020

Includes: Supplemental data

Journal Articles

Dysregulation of Hemostatic Biomarkers, Inflammatory Biomarkers, and Alteration of Cellular Indices As Predictors of Adverse Outcomes in Pulmonary Embolism Patients

Iman Darwish, Yevgeniy Brailovsky, DO, Amir Darki, MD MSc, Debra Hoppensteadt, PhD, Brett Slajus, Emily Bontekoe, Frank De Stefano, Jawed Fareed, PhD

Blood (2019) 134 (Supplement_1): 2408.

https://doi.org/10.1182/blood-2019-126876

Published: 2019

Journal Articles

Circulating Plasminogen Activator Inhibitor-1 (PAI-1) Is Reduced By In Vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC)

Sara Reda, MD, Franziska Isabelle Winterhagen, Christina Berens, MD, Jens Müller, Johannes Oldenburg, Bernd Pötzsch, MD, Heiko Rühl, MD

Blood (2019) 134 (Supplement_1): 2389.

https://doi.org/10.1182/blood-2019-124731

Published: 2019

Journal Articles

Markedly Reduced Expression of Annexin A2 Is Associated with Hypofibrinolysis and Provoked and Unprovoked Venous Thromboembolism

Hannah Fassel, MD, Huigen Chen, MS, Mary Ruisi, MD, Maria Teresa De Sancho, MD, Katherine A. Hajjar, MD

Blood (2019) 134 (Supplement_1): 443.

https://doi.org/10.1182/blood-2019-127426

Published: 2019

Journal Articles

Prevention of Bleeding-Induced Vascular Abnormalities in the Hemophilic Mouse Joint By Increasing TAFI Levels or Inhibiting uPA Activity

Tine Wyseure, PhD, Niels Behrendt, Annette von Drygalski, MD PharmD, Laurent O Mosnier

Blood (2019) 134 (Supplement_1): 158.

https://doi.org/10.1182/blood-2019-128723

Published: 2019

Journal Articles

Altered Angiogenic Gene Expression Profiles in Porcine Von Willebrand Disease

Mario von Depka, MD PhD, Katharina Kaiser, Carsten Detering, MSc, Mahnaz Ekhlasi-Hundrieser, PhD, Christiane Pfarrer, DVM, Prof, Stefanie Lehner, DVM, PhD

Blood (2019) 134 (Supplement_1): 4917.

https://doi.org/10.1182/blood-2019-122407

Published: 2019

Journal Articles

Regulation of Coagulation by Polyphosphate

Nicola J. Mutch, BSc, PhD

Blood (2019) 134 (Supplement_1): SCI-18.

https://doi.org/10.1182/blood-2019-121062

Published: 2019

Journal Articles

Venous stasis-induced fibrinolysis prevents thrombosis in mice: role of α2-antiplasmin

Satish Singh, Aiilyan K. Houng, Guy L. Reed

Blood (2019) 134 (12): 970–978.

https://doi.org/10.1182/blood.2019000049

Published: 2019

Includes: Supplemental data

Journal Articles

Differential expression of Plg-R KT and its effects on migration of proinflammatory monocyte and macrophage subsets

Barbara Thaler, Nagyung Baik, Philipp J. Hohensinner, Johanna Baumgartner, Adelheid Panzenböck, Stefan Stojkovic, Svitlana Demyanets, Ihor Huk, Gersina Rega-Kaun, Christoph Kaun, Manfred Prager, Michael B. Fischer, Kurt Huber, Walter S. Speidl, Robert J. Parmer, Lindsey A. Miles, Johann Wojta

Blood (2019) 134 (6): 561–567.

https://doi.org/10.1182/blood.2018850420

Published: 2019

Journal Articles

Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation

Lakmali Munasinghage Silva, Andrew Gary Lum, Collin Tran, Molly W. Shaw, Zhen Gao, Matthew J. Flick, Niki M. Moutsopoulos, Thomas H. Bugge, Eric S. Mullins

Blood (2019) 134 (3): 291–303.

https://doi.org/10.1182/blood.2018874859

Published: 2019

Includes: Supplemental data

Journal Articles

Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications

Katherine J. Kearney, Nikoletta Pechlivani, Rhodri King, Christian Tiede, Fladia Phoenix, Ramsah Cheah, Fraser L. Macrae, Katie J. Simmons, Iain W. Manfield, Kerrie A. Smith, Benjamin E. J. Spurgeon, Khalid M. Naseem, Robert A. S. Ariens, Michael J. McPherson, Darren C. Tomlinson, Ramzi A. Ajjan

Blood (2019) 133 (11): 1233–1244.

https://doi.org/10.1182/blood-2018-06-856195

Published: 2019

Includes: Supplemental data

Journal Articles

Relationship of Markers of Inflammation, Infection and Endothelial Function to Mortality and Severity of Coagulopathy in Patients with Sepsis-Associated DIC

Debra Hoppensteadt, PhD, Amanda Walborn, PhD, Matthew T. Rondina, MD, Jawed Fareed, PhD

Blood (2018) 132 (Supplement 1): 2495.

https://doi.org/10.1182/blood-2018-99-115302

Published: 2018

Journal Articles

Human Plasminogen Replacement Therapy Vs. Best Supportive Care in Patients with Congenital Plasminogen Deficiency: A Comparison of Health Care Resource Use over a 48-Week Period

George Dranitsaris, PhD, Amparo Santamaria Ortiz, MD, Kristine Dorward, MBA, Hande Kizilocak, PhD, Tiraje Celkan, MD

Blood (2018) 132 (Supplement 1): 2232.

https://doi.org/10.1182/blood-2018-99-117184

Published: 2018

Journal Articles

Plasmin-Mediated Fibrinolysis Enables Macrophage Migration Via Liberation from Fibrin-α M β 2 Interactions

Eric S. Mullins, MD, Maureen A. Shaw, MSc, Zhen Gao, PhD, Matthew J. Flick, PhD

Blood (2018) 132 (Supplement 1): 136.

https://doi.org/10.1182/blood-2018-99-117018

Published: 2018

Journal Articles

The Hypofibrinolytic Defect of Nephrotic Syndrome Is Directly Proportional to Fibrin Network Density

Amanda P. Waller, PhD, Katelyn J Wolfgang, Bryce A. Kerlin, MD

Blood (2018) 132 (Supplement 1): 1218.

https://doi.org/10.1182/blood-2018-99-119947

Published: 2018

Journal Articles

Hepatocyte-Derived Tissue Plasminogen Activator Regulates Systemic Fibrinolysis

Ze Zheng, MDPhD, Lalitha V. Nayak, MD, Mukesh Jain, Ira Tabas, MD PhD

Blood (2018) 132 (Supplement 1): 217.

https://doi.org/10.1182/blood-2018-99-119362

Published: 2018

Journal Articles

Hyperactivation of Plasmin Following Severe Burn Is Associated with Systemic Inflammation and Coagulopathy

Breanne HY Gibson, BSc, Patrick R Keller, BA, BM, Stephanie N Moore-Lotridge, BSc, J. Blair Summitt, MD, Jonathan G Schoenecker, MD PhD

Blood (2018) 132 (Supplement 1): 3780.

https://doi.org/10.1182/blood-2018-99-116904

Published: 2018

Journal Articles

Sugimoto MA, Ribeiro ALC, Costa BRC, et al. Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1. Blood . 2017;129(21):2896-2907.

Blood (2018) 132 (4): 459.

https://doi.org/10.1182/blood-2018-05-854158

Published: 2018

NARROW

Plasminogen: an enigmatic zymogen

Reduced expression of annexin A2 is associated with impaired cell surface fibrinolysis and venous thromboembolism

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Dysregulation of Hemostatic Biomarkers, Inflammatory Biomarkers, and Alteration of Cellular Indices As Predictors of Adverse Outcomes in Pulmonary Embolism Patients

Circulating Plasminogen Activator Inhibitor-1 (PAI-1) Is Reduced By In Vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC)

Markedly Reduced Expression of Annexin A2 Is Associated with Hypofibrinolysis and Provoked and Unprovoked Venous Thromboembolism

Prevention of Bleeding-Induced Vascular Abnormalities in the Hemophilic Mouse Joint By Increasing TAFI Levels or Inhibiting uPA Activity

Altered Angiogenic Gene Expression Profiles in Porcine Von Willebrand Disease

Regulation of Coagulation by Polyphosphate

Venous stasis-induced fibrinolysis prevents thrombosis in mice: role of α2-antiplasmin

Differential expression of Plg-R KT and its effects on migration of proinflammatory monocyte and macrophage subsets

Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation

Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications

Relationship of Markers of Inflammation, Infection and Endothelial Function to Mortality and Severity of Coagulopathy in Patients with Sepsis-Associated DIC

Human Plasminogen Replacement Therapy Vs. Best Supportive Care in Patients with Congenital Plasminogen Deficiency: A Comparison of Health Care Resource Use over a 48-Week Period

Plasmin-Mediated Fibrinolysis Enables Macrophage Migration Via Liberation from Fibrin-α M β 2 Interactions

The Hypofibrinolytic Defect of Nephrotic Syndrome Is Directly Proportional to Fibrin Network Density

Hepatocyte-Derived Tissue Plasminogen Activator Regulates Systemic Fibrinolysis

Hyperactivation of Plasmin Following Severe Burn Is Associated with Systemic Inflammation and Coagulopathy

Sugimoto MA, Ribeiro ALC, Costa BRC, et al. Plasmin and plasminogen induce macrophage reprogramming and regulate key steps of inflammation resolution via annexin A1. Blood . 2017;129(21):2896-2907.

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American Society of Hematology

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American Society of Hematology

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