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Journal Articles

Indirubins: A Potential Therapeutic Target in Multiple Myeloma

Tina Bagratuni, Nicolas Gaboriad-Kolar, Roubini Zakopoulou, Vassilios Myrianthopoulos, Efstathios Kastritis, MD, Evangelos Terpos, Emmanuel Mikros, Alexios-Leandros Skaltsounis, Meletios A Dimopoulos

Blood (2016) 128 (22): 3259.

https://doi.org/10.1182/blood.V128.22.3259.3259

Published: 2016

Journal Articles

Combined Targeting of β-Catenin and FLT-3 Is Synergistically Lethal Against Cultured and Primary AML Blast Progenitor Cells Expressing FLT3 Internal Tandem Duplication (ITD)

Saikat Saha, PhD, Warren Fiskus, PhD, Sunil Sharma, Bhavin Shah, Anna T Rogojina, Santhana G. T. Devaraj, PhD, Baohua Sun, MD PhD, Christopher Leveque, MD, Youli Zu, MD PhD, Swaminathan Padmanabhan Iyer, MD, Kapil N. Bhalla, MD

Blood (2014) 124 (21): 618.

https://doi.org/10.1182/blood.V124.21.618.618

Published: 2014

Journal Articles

Pre-Clinical Efficacy of Combined Therapy with Novel β-Catenin Antagonist BC2059 and Histone Deacetylase Inhibitor Against Cultured and Primary AML Blast Progenitor Cells

Kapil Bhalla, MD, Warren Fiskus, Ph.D., Stephen K. Horrigan, PhD, Sunil Abhyankar, MD, Joseph McGuirk, DO, Sunil Sharma, MD

Blood (2012) 120 (21): 287.

https://doi.org/10.1182/blood.V120.21.287.287

Published: 2012

Journal Articles

GSK3β Inhibition Promotes T Cell Reconstitution and Preserves Naive T Cell Phenotype in Bone Marrow Reconstituted Mice

Shen Sylvie, PhD, Ning Xu, PhD, Guy Klamer, Tracey O'Brien, MD, Alla Dolnikov, PhD

Blood (2012) 120 (21): 1890.

https://doi.org/10.1182/blood.V120.21.1890.1890

Published: 2012

Journal Articles

Treatment with β-Catenin Antagonist BC2059 Exerts Single Agent Efficacy and Exerts Improved Activity with Tyrosine Kinase Inhibitor (TKI) or Pan-Histone Deacetylase (HDAC) Inhibitor Against Human CML and Myeloproliferative Neoplasm (MPN) Progenitor Cells

Warren Fiskus, PhD, Jacqueline Smith, MS, Uma Mudunuru, MS, Stacey Hembruff, MS, Ruben Reyes, MD, Sunil Abhyankar, MD, Joseph McGuirk, DO, Omar S. Aljitawi, MD, Siddhartha Ganguly, MD, Stephen K. Horrigan, PhD, Sunil Sharma, MD, Kapil N. Bhalla, MD

Blood (2011) 118 (21): 65.

https://doi.org/10.1182/blood.V118.21.65.65

Published: 2011

Journal Articles

Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma–induced bone disease in a novel murine plasmacytoma xenograft model

W. Grady Gunn, Ulf Krause, Narae Lee, Carl A. Gregory

Blood (2011) 117 (5): 1641–1651.

https://doi.org/10.1182/blood-2010-09-308171

Published: 2011

Includes: Supplemental data

Journal Articles

The GM-CSF Receptor Utilises Members of the Canonical Wnt-Signaling Pathway during Macrophage Differentiation

Anna Brown, BSc, PhD, Diana Salerno, Christopher Wilkinson, Michelle Perugini, Chung Kok, Greg Goodall, Patricia Solomon, Thomas Gonda, Richard D’Andrea, PhD

Blood (2008) 112 (11): 3856.

https://doi.org/10.1182/blood.V112.11.3856.3856

Published: 2008

Journal Articles

Wnt/β-Catenin Pathway Affects the Cell-Fate Decisions of Hematopoietic Stem/Progenitor Cells Modulating the Epigenetic States of Various Essential Transcription Factors

Hirokazu Tanaka, M.D., Ph.D., Itaru Matsumura, M.D., Ph.D., Yusuke Satoh, M.D., Ph.D., Sachiko Ezoe, M.D., Ph.D., Tatsutoshi Nakahata, M.D., Ph.D., Yuzuru Kanakura, M.D., Ph.D.

Blood (2008) 112 (11): 2433.

https://doi.org/10.1182/blood.V112.11.2433.2433

Published: 2008

Journal Articles

Glycogen Synthase Kinase-3β Regulates Ex-Vivo Expansion and Engraftment of Umbilical Cord Blood Hematopoietic Stem Cells through the Activation of Wnt Signaling.

Alla Dolnikov, PhD, Tiffany Holmes, MSc, Tracey A. O’Brien, MBChB,FRACP,MHL,BSc

Blood (2006) 108 (11): 340.

https://doi.org/10.1182/blood.V108.11.340.340

Published: 2006

Journal Articles

A Novel Suicide Gene Therapy Approach for Reduction of GvHD Using Lentiviral Delivery of a Modified Human Thymidylate Monophosphate Kinase.

Takeya Sato, PhD, Anton Neschadim, Vanessa I. Rasaiah, Manfred Konrad, PhD, Daniel H. Fowler, MD, Arnon Lavie, PhD, Jeffrey A. Medin, PhD

Blood (2005) 106 (11): 5252.

https://doi.org/10.1182/blood.V106.11.5252.5252

Published: 2005

Journal Articles

The Effect of GSK3β Inhibitor on Murine Multipotent Adult Progenitor Cells (mMAPCs).

Masayuki Oki, MD, Yuehua Jiang, MD, Catherine M. Verfaillie, MD

Blood (2005) 106 (11): 1705.

https://doi.org/10.1182/blood.V106.11.1705.1705

Published: 2005

Journal Articles

Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G 1 phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex

Yukimasa Shiotsu, Leonard M. Neckers, Ivo Wortman, Won G. An, Theodor W. Schulte, Shiro Soga, Chikara Murakata, Tatsuya Tamaoki, Shiro Akinaga

Blood (2000) 96 (6): 2284–2291.

https://doi.org/10.1182/blood.V96.6.2284

Published: 2000

NARROW

Indirubins: A Potential Therapeutic Target in Multiple Myeloma

Combined Targeting of β-Catenin and FLT-3 Is Synergistically Lethal Against Cultured and Primary AML Blast Progenitor Cells Expressing FLT3 Internal Tandem Duplication (ITD)

Pre-Clinical Efficacy of Combined Therapy with Novel β-Catenin Antagonist BC2059 and Histone Deacetylase Inhibitor Against Cultured and Primary AML Blast Progenitor Cells

GSK3β Inhibition Promotes T Cell Reconstitution and Preserves Naive T Cell Phenotype in Bone Marrow Reconstituted Mice

Treatment with β-Catenin Antagonist BC2059 Exerts Single Agent Efficacy and Exerts Improved Activity with Tyrosine Kinase Inhibitor (TKI) or Pan-Histone Deacetylase (HDAC) Inhibitor Against Human CML and Myeloproliferative Neoplasm (MPN) Progenitor Cells

Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma–induced bone disease in a novel murine plasmacytoma xenograft model

The GM-CSF Receptor Utilises Members of the Canonical Wnt-Signaling Pathway during Macrophage Differentiation

Wnt/β-Catenin Pathway Affects the Cell-Fate Decisions of Hematopoietic Stem/Progenitor Cells Modulating the Epigenetic States of Various Essential Transcription Factors

Glycogen Synthase Kinase-3β Regulates Ex-Vivo Expansion and Engraftment of Umbilical Cord Blood Hematopoietic Stem Cells through the Activation of Wnt Signaling.

A Novel Suicide Gene Therapy Approach for Reduction of GvHD Using Lentiviral Delivery of a Modified Human Thymidylate Monophosphate Kinase.

The Effect of GSK3β Inhibitor on Murine Multipotent Adult Progenitor Cells (mMAPCs).

Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G 1 phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex

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American Society of Hematology

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ASH Publications

American Society of Hematology

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