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Journal Articles

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

Kadriye Nehir Cosgun, PhD, Gauri Deb, MS, PhD, Xin Yang, MD, Gang Xiao, PhD, Teresa Sadras, PhD, Jaewoong Lee, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Lu Yang, PhD, Huimin Geng, PhD, John Chan, MD, Joo Y. Song, MD, Hassan Jumaa, PhD, Andrew G. Polson, PhD, Hans Clevers, MD PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 748.

https://doi.org/10.1182/blood-2019-127263

Published: 2019

Journal Articles

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Kamaleldin E Elagib, PhDMBBS, Ashton Brock, PhD, Goar Mosoyan, Cara Clementelli, Lorrie L Delehanty, BS, Alexandra Pacheco-Benichou, Corinne Fruit, Thierry Besson, PhD, Stephen Morris, MD, Koji Eto, MD, Camelia Iancu-Rubin, PhD, Adam N Goldfarb, MD

Blood (2019) 134 (Supplement_1): 3250.

https://doi.org/10.1182/blood-2019-129049

Published: 2019

Journal Articles

Botanical Alkyl Hydroquinone Derivative HQ17(3) Induces Calcium-Associated Mitochondrial Damage and Mitophagy to Exert Ctotoxicity to Philadelphila Chromosome(+) ALL Cells

Yin-Chen Chou, MS, Chia-Wei Chen, MS, Yuan-Yeh Kuo, PhD, Liang-In Lin, PhD, Chung-Yi Hu, PhD

Blood (2018) 132 (Supplement 1): 5800.

https://doi.org/10.1182/blood-2018-99-120307

Published: 2018

Journal Articles

Novel nonsense gain-of-function NFKB2 mutations associated with a combined immunodeficiency phenotype

Hye Sun Kuehn, Julie E. Niemela, Karthik Sreedhara, Jennifer L. Stoddard, Jennifer Grossman, Christian A. Wysocki, M. Teresa de la Morena, Mary Garofalo, Jingga Inlora, Michael P. Snyder, David B. Lewis, Constantine A. Stratakis, Thomas A. Fleisher, Sergio D. Rosenzweig

Blood (2017) 130 (13): 1553–1564.

https://doi.org/10.1182/blood-2017-05-782177

Published: 2017

Includes: Supplemental data

Journal Articles

SYK-Inhibitor Bay 61-3606 Induces Cell Cycle Arrest and Apoptosis in Multiple Myeloma Cells Independent of SYK Inhibitory Effects but Via Degradation of IKZF1/3

Shirong Li, PhD, Jing Fu, PhD, Jing Wu, MD PhD, Markus Y Mapara, MD PhD, Suzanne Lentzsch, MD PhD

Blood (2016) 128 (22): 4477.

https://doi.org/10.1182/blood.V128.22.4477.4477

Published: 2016

Journal Articles

Combining Effects of the SMO Inhibitor and Jak1 Inhibitor in Terminal Differentiation of MDS-Derived Induced Potent Stem Cells (iPSC)

Tetsuzo Tauchi, MDPhD, Seiichi Okabe, MD PhD, Seiichiro Katagiri, MD, Yuko Tanaka, MDPhD, Kazuma Ohyashiki, MD PhD

Blood (2016) 128 (22): 3150.

https://doi.org/10.1182/blood.V128.22.3150.3150

Published: 2016

Journal Articles

ROS Production Triggers Anti-Leukemic Effects of Green Tea

Cristiane Okuda Torello, PhD, Rodrigo Naoto Shiraishi, Fernanda Isabel Della Via, Mary L S Queiroz, MD PhD, Sara Teresinha Olalla Saad, MD PhD, Eduardo Magalhaes Rego, PhD

Blood (2016) 128 (22): 5219.

https://doi.org/10.1182/blood.V128.22.5219.5219

Published: 2016

Journal Articles

Inhibition of CML Stem Cell Renewal By the Porcupine Inhibitor WNT974

Puneet Agarwal, MS, Bin Zhang, PhD, Yinwei Ho, MS, Amy Cook, PhD, Ling Li, PhD, Youzhen Wang, PhD, Margaret E Mclaughlin, MD, Ravi Bhatia, MD

Blood (2015) 126 (23): 54.

https://doi.org/10.1182/blood.V126.23.54.54

Published: 2015

Journal Articles

Delta-Aminolevulinate Preferentially Induces Gamma-Globin Expression in Erythroid Cells through Activation of NRF2 Stress Response

Li Liu, PhD BS, MS, Christina Torres, Baolin Kang, PhD, Betty Pace, MD

Blood (2015) 126 (23): 3387.

https://doi.org/10.1182/blood.V126.23.3387.3387

Published: 2015

Journal Articles

PIM2 Pro-Survival Functions Are Mediated By RSK2 in AML

Marie-Anne Hospital, MD, Arnaud Jacquel, PhD, Alexa Green, Mireille Lambert, PhD, Patrick Auberger, PhD, Catherine Lacombe, Olivier Hermine, MD PhD, Ivan C Moura, PhD, Patrick Mayeux, PhD, Didier Bouscary, MD, Jerome Tamburini, MD PhD

Blood (2014) 124 (21): 912.

https://doi.org/10.1182/blood.V124.21.912.912

Published: 2014

Journal Articles

Anergy in CLL: Moving Towards the Clinic

Benedetta Apollonio, Tania Veliz Rodriguez, Cristina Scielzo, PhD, Maria Teresa Sabrina Bertilaccio, Lydia Scarfò, Federico Caligaris-Cappio, MD, Paolo Ghia, MD PhD

Blood (2014) 124 (21): 4677.

https://doi.org/10.1182/blood.V124.21.4677.4677

Published: 2014

Journal Articles

Inhibition of CML Stem Cell Growth By Targeting WNT Signaling Using a Porcupine Inhibitor

Puneet Agarwal, MS, Bin Zhang, PhD, YinWei Ho, Amy Cook, PhD, Ling Li, PhD, Youzhen Wang, Margaret McLaughlin, PhD, Ravi Bhatia, MD

Blood (2014) 124 (21): 3130.

https://doi.org/10.1182/blood.V124.21.3130.3130

Published: 2014

Journal Articles

Role of the Polycomb Gene Bcor in Hematopoiesis

Tomoyuki Tanaka, MD, Yaeko Nakajima-Takagi, PhD, Sha Si, Atsunori Saraya, MS, Sone Hirohito, MDPhD, Haruhiko Koseki, MD PhD, Atsushi Iwama, MD, PhD

Blood (2014) 124 (21): 4312.

https://doi.org/10.1182/blood.V124.21.4312.4312

Published: 2014

Journal Articles

Constitutive and Immunoproteasome Inhibitors Increase IκB and Decrease NF-κB Expression In Dendritic Cell

Ahmad-Samer Samer Al-Homsi, MD, Zhongbin Lai, MD, PhD, Tara Sabrina Roy, NP, Niholas Kouttab

Blood (2013) 122 (21): 3493.

https://doi.org/10.1182/blood.V122.21.3493.3493

Published: 2013

Journal Articles

MUC1 Expression Is Essential For Establishment Of Acute Myeloid Leukemia In Vivo

Dina Stroopinsky, PhD, Hasan Rajabi, PhD, Jacalyn Rosenblatt, MD, Heidi Mills, BA, Turner Kufe, Katarina Luptakova, MD, Baldev Vasir, PhD, Maxwell D Coll, Palmer Kristen, Akriti Kharbanda, Srivastava Neeharika, MD, Robin Joyce, MD, James D. Levine, MD, Jon Arnason, MD, Richard M. Stone, MD, Pier Paolo Pandolfi, MD, PhD, Donald Kufe, MD, David Avigan, MD

Blood (2013) 122 (21): 3787.

https://doi.org/10.1182/blood.V122.21.3787.3787

Published: 2013

Journal Articles

Transcriptional Mistargeting Of NFAT2 In CLL

Melanie Märklin, M. Sc., Jonas S. Heitmann, B. Sc., David Worbs, B. Sc., Alexandra Poljak, B. Sc., Claude Evouna, MD, Hans-Georg Kopp, MD, Lothar Kanz, MD, Anjana Rao, PhD, Stefan Wirths, MD, Martin R Müller, MD, PhD

Blood (2013) 122 (21): 4122.

https://doi.org/10.1182/blood.V122.21.4122.4122

Published: 2013

Journal Articles

Targeting B-cell anergy in chronic lymphocytic leukemia

Benedetta Apollonio, Cristina Scielzo, Maria Teresa Sabrina Bertilaccio, Elisa ten Hacken, Lydia Scarfò, Pamela Ranghetti, Freda Stevenson, Graham Packham, Paolo Ghia, Marta Muzio, Federico Caligaris-Cappio

Blood (2013) 121 (19): 3879–3888.

https://doi.org/10.1182/blood-2012-12-474718

Published: 2013

Includes: Supplemental data

Journal Articles

SGI-110, a Novel Hypomethylating Agent, Induces the WNT Inhibitor Secreted Frizzled Related Protein-2 ( SFRP2 ), and Down Regulates β-Catenin in Acute Myeloid Leukemia (AML) Cells

Michelle Golding, Pragya Srivastava, PhD, Golda Collamat, MS, Smitha R James, MS, Adam R. Karpf, PhD, Michael J. Nemeth, PhD, Elizabeth A Griffiths, MD

Blood (2012) 120 (21): 1290.

https://doi.org/10.1182/blood.V120.21.1290.1290

Published: 2012

Journal Articles

Overexpression and Aberrant Nuclear Translocation of NFAT2 in CLL

Jonas S. Heitmann, B. Sc., Melanie Märklin, M. Sc., Alexandra Poljak, B. Sc., Bettina S, Hackl, B. Sc., Juliane Sarah Stickel, MD, Lothar Kanz, MD, Hans-Georg Kopp, MD, Stefan Wirths, MD, Martin R Müller, MD, PhD

Blood (2012) 120 (21): 3909.

https://doi.org/10.1182/blood.V120.21.3909.3909

Published: 2012

Journal Articles

Episomal Anchorage Maintains Non-Integrating Lentiviral Vectors in Dividing Cells

Santhosh Chakkaramakkil Verghese, Ph.D, Amy M. Skinner, Ph.D., Karen L Huan, Hans J Lipps, Ph.D, Peter Kurre, MD

Blood (2012) 120 (21): 4224.

https://doi.org/10.1182/blood.V120.21.4224.4224

Published: 2012

NARROW

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Botanical Alkyl Hydroquinone Derivative HQ17(3) Induces Calcium-Associated Mitochondrial Damage and Mitophagy to Exert Ctotoxicity to Philadelphila Chromosome(+) ALL Cells

Novel nonsense gain-of-function NFKB2 mutations associated with a combined immunodeficiency phenotype

SYK-Inhibitor Bay 61-3606 Induces Cell Cycle Arrest and Apoptosis in Multiple Myeloma Cells Independent of SYK Inhibitory Effects but Via Degradation of IKZF1/3

Combining Effects of the SMO Inhibitor and Jak1 Inhibitor in Terminal Differentiation of MDS-Derived Induced Potent Stem Cells (iPSC)

ROS Production Triggers Anti-Leukemic Effects of Green Tea

Inhibition of CML Stem Cell Renewal By the Porcupine Inhibitor WNT974

Delta-Aminolevulinate Preferentially Induces Gamma-Globin Expression in Erythroid Cells through Activation of NRF2 Stress Response

PIM2 Pro-Survival Functions Are Mediated By RSK2 in AML

Anergy in CLL: Moving Towards the Clinic

Inhibition of CML Stem Cell Growth By Targeting WNT Signaling Using a Porcupine Inhibitor

Role of the Polycomb Gene Bcor in Hematopoiesis

Constitutive and Immunoproteasome Inhibitors Increase IκB and Decrease NF-κB Expression In Dendritic Cell

MUC1 Expression Is Essential For Establishment Of Acute Myeloid Leukemia In Vivo

Transcriptional Mistargeting Of NFAT2 In CLL

Targeting B-cell anergy in chronic lymphocytic leukemia

SGI-110, a Novel Hypomethylating Agent, Induces the WNT Inhibitor Secreted Frizzled Related Protein-2 ( SFRP2 ), and Down Regulates β-Catenin in Acute Myeloid Leukemia (AML) Cells

Overexpression and Aberrant Nuclear Translocation of NFAT2 in CLL

Episomal Anchorage Maintains Non-Integrating Lentiviral Vectors in Dividing Cells

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American Society of Hematology

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American Society of Hematology

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