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Journal Articles

Pre-Clinical Efficacy of Co-Treatment with KDM1A (LSD1) Inhibitor and Ruxolitinib or BET Inhibitor Against Post-MPN-sAML Blast Progenitor Cells

Warren Fiskus, BSc,PhD, Christopher Peter Mill, PhD BA, Vrajesh Karkhanis, PhD, Bernardo H Lara, Prithviraj Bose, MD, Lucia Masarova, Tapan M. Kadia, MD, Nancy Shao, Isean Bhalla, James V Maher, Joseph D. Khoury, MD, Sunil Sharma, MD, Taghi Manshouri, PhD, Srdan Verstovsek, MD PhD, Kapil N. Bhalla, MD

Blood (2019) 134 (Supplement_1): 1274.

https://doi.org/10.1182/blood-2019-130783

Published: 2019

Journal Articles

New Generation Chimeric Antigen Receptor T-Cell Therapy (CoupledCAR) Induces High Rate Remissions in Solid Tumor

Lei Xiao, PhD

Blood (2019) 134 (Supplement_1): 4631.

https://doi.org/10.1182/blood-2019-130703

Published: 2019

Journal Articles

The Embryonic Program Activated during Blast Crisis of Chronic Myelogenous Leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding and Represents a Druggable Target

Christophe Desterke, PhD, Sarah Pagliaro, Pharm D, Patricia Hugues, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2019) 134 (Supplement_1): 1632.

https://doi.org/10.1182/blood-2019-124796

Published: 2019

Journal Articles

A Novel BCL-2/BCL-Xl Dual Inhibitor Overcomes Ibrutinib-Resistance Conferred By the Upregulation of Integrin Pathway and BCL-Xl

Jing Deng, PhD, Tingting Mao, MS, Xiaojing Huang, PhD, Li Rui, Guangfeng Wang, PhD, Douglas D. Fang, MD PhD, Dajun Yang, MD PhD, Yifan Zhai, MD PhD

Blood (2019) 134 (Supplement_1): 2573.

https://doi.org/10.1182/blood-2019-128708

Published: 2019

Journal Articles

Synergistic Pre-Clinical Activity of Targeted Inhibition of KDM1A and BET Proteins Against Human AML Blast Progenitor Cells

Warren Fiskus, BSc, PhD, Christopher Peter Mill, PhD BA, Raffaella Soldi, Roulan Han, Dyana T. Saenz, PhD, Agnieszka J Nowak, Baohua Sun, MD PhD, David N Saenz, Courtney D. DiNardo, MD MSc, Gautam Borthakur, MD, Tapan M. Kadia, MD, Wendy Jin, Thurika Ganesh, Vaishnavi Rao, Joseph David Khoury, MD, Sunil Sharma, MD, Kapil N. Bhalla, MD

Blood (2018) 132 (Supplement 1): 3930.

https://doi.org/10.1182/blood-2018-99-114198

Published: 2018

Journal Articles

Probing Distinct Oncogene Addiction By Novel BCL-2 Inhibitors

Jing Deng, PhD, Yan Yin, MS, Tingting Mao, MS, Guoqin Zhai, MS, Dongmei Yang, MS, Douglas Fang, MD PhD, Shaomeng Wang, PhD, Yifan Zhai, MD PhD, Dajun Yang, MD PhD

Blood (2018) 132 (Supplement 1): 2616.

https://doi.org/10.1182/blood-2018-99-119816

Published: 2018

Journal Articles

Reversal of Chemoresistance in Leukemia Cells Using Synthetic Bisbenzylisoquinoline Derivatives

Martin Müller, Susanne Gerndt, Anja Arner, Yu-Kai Chao, Linus Schömig, Carina Atzberger, Martin Biel, Franz Bracher, Angelika Vollmar, Vera Binder, MD, Marco Keller, Christian Grimm, Karin Bartel

Blood (2018) 132 (Supplement 1): 3504.

https://doi.org/10.1182/blood-2018-99-111651

Published: 2018

Journal Articles

Feasibility of a Smartphone-Based Health Coaching Intervention for Patient Self-Management of Nutrition in the Post-Chemotherapy Setting

Connie E Chen, MD, Alice Y Mao, Jontrice G Murray, Betul Oran, MD, Muzaffar H. Qazilbash, MD, Nina Shah, MD, Sairah Ahmed, MD, Qaiser Bashir, MD, Chitra Hosing, MD, Elizabeth J. Shpall, MD, Joseph R Steele, MD, Richard E. Champlin, MD, Simrit Parmar, MD

Blood (2016) 128 (22): 3554.

https://doi.org/10.1182/blood.V128.22.3554.3554

Published: 2016

Journal Articles

Markers of Oxidative Stress Do Not Correlate with Labile Plasma Iron Blood in Patients with Myelodysplastic Syndromes

Christian Rose, MD, Fathi Driss, Veronique Mansat De Mas, Odile Beyne-Rauzy, MD PhD, Emmanuel Gyan, MD PhD, Yongmin MA, Robert Hider, Pierre Fenaux, MD PhD, Carole Beaumont, PhD

Blood (2015) 126 (23): 2149.

https://doi.org/10.1182/blood.V126.23.2149.2149

Published: 2015

Journal Articles

Novel Epigenetic Modulators That Promote Fetal Hemoglobin Production for the Prevention of Sickle Cell Disease Related Complications

Rebecca M. Cafiero, MD, Steven Holshouser, Craig Kutz, Julie Kanter, MD, Patrick Woster, PhD

Blood (2015) 126 (23): 973.

https://doi.org/10.1182/blood.V126.23.973.973

Published: 2015

Journal Articles

Shear-Dependent Fibrillogenesis of Fibronectin: Impact of Platelet Integrins and Actin Cytoskeleton

Huong T. T. Nguyen, MSc, Khon C. Huynh, PhD, Volker R. Stoldt, PhD, Rudiger E. Scharf, MD FAHA

Blood (2014) 124 (21): 1443.

https://doi.org/10.1182/blood.V124.21.1443.1443

Published: 2014

Journal Articles

Pharmacological Inhibitors of LSD1 Promote Differentiation of Myeloid Leukemia Cells through a Mechanism Independent of Histone Demethylation

James T Lynch, PhD, Gary J Spencer, PhD, William J Harris, PhD, Alba Maiques-Díaz, PhD, Filippo Ciceri, PhD, Xu Huang, PhD, Tim C P Somervaille, PhD FRCP, FRCPath

Blood (2014) 124 (21): 267.

https://doi.org/10.1182/blood.V124.21.267.267

Published: 2014

Journal Articles

Targeting The PI3K/AKT Pathway To Inhibit Platelet Activation and Thrombus Formation

Wenxiu Yi, BS, Wei Li, MS, Lijie Ren, MS, Xinliang Mao, MD, PhD, Li Zhu, MD, PhD

Blood (2013) 122 (21): 3513.

https://doi.org/10.1182/blood.V122.21.3513.3513

Published: 2013

Journal Articles

Histone H3 Methylation Mediates All- Trans -Retinoic Acid Responsiveness in Acute Myeloid Leukemia

Tino Schenk, PhD, Stefanie Göllner, PhD, Weihsu Claire Chen, PhD, Louise Howell, BSc, Liqing Jin, MD, Katja Hebestreit, Hans-Ulrich Klein, PhD, Alan K Burnett, MD, Ken I. Mills, PhD, FRCPath, Laurence Marton, MD, Robert Casero, Jr., PhD, Patrick Woster, PhD, Martin Dugas, MD, Jean C.Y. Wang, MD, PhD, John E. Dick, PhD, Carsten Müller-Tidow, MD, Kevin Petrie, PhD, Arthur Zelent, PhD

Blood (2011) 118 (21): 224.

https://doi.org/10.1182/blood.V118.21.224.224

Published: 2011

Journal Articles

HDAC and LSD1 Inhibitors Synergize to Induce Cell Death in Acute Leukemia Cells

Lorimar Ramirez, MD, Melissa Singh, PhD, Joya Chandra, PhD

Blood (2011) 118 (21): 1427.

https://doi.org/10.1182/blood.V118.21.1427.1427

Published: 2011

Journal Articles

Serum ceruloplasmin protein expression and activity increases in iron-deficient rats and is further enhanced by higher dietary copper intake

Perungavur N. Ranganathan, Yan Lu, Lingli Jiang, Changae Kim, James F. Collins

Blood (2011) 118 (11): 3146–3153.

https://doi.org/10.1182/blood-2011-05-352112

Published: 2011

Includes: Supplemental data

Journal Articles

Clioquinol Arrests Cell Cycle at G1 Phase and Triggers Intrinsic Apoptosis In Myeloma and Leukemia Cells by Inhibiting Histone Deacetylases

Biyin Cao, Tingjun Hou, PhD, Suning Chen, Depei Wu, Aining Sun, Huiying Qiu, Wenjie Wang, Aaron Schimmer, MD, PhD, Xinliang Mao, MD, PhD

Blood (2010) 116 (21): 1836.

https://doi.org/10.1182/blood.V116.21.1836.1836

Published: 2010

Journal Articles

Comparison of B Cell Depletion Mediated by Intravenous (IV) Rituxan® and Rituxan Given Subcutaneous (SC) In Cynomolgus Monkeys

Christopher J Del Nagro, Cheng Ping Mao, Martin Brovarney, Karim Dabbagh, Herbert Birnboeck, Wolfgang F Richter

Blood (2010) 116 (21): 3980.

https://doi.org/10.1182/blood.V116.21.3980.3980

Published: 2010

Journal Articles

Granulocyte Colony-Stimulating Factor (G-CSF) Stimulates Sympathetic Nervous System Activity in the Bone Marrow

Michela Battista, PhD, Simon Mendez-Ferrer, PhD, Paul S. Frenette, M.D.

Blood (2008) 112 (11): 2419.

https://doi.org/10.1182/blood.V112.11.2419.2419

Published: 2008

Journal Articles

Lock 'n' roll with VAP-1

Suchitra Sumitran-Holgersson

Blood (2007) 110 (6): 1706–1707.

https://doi.org/10.1182/blood-2007-06-095240

Published: 2007

NARROW

Pre-Clinical Efficacy of Co-Treatment with KDM1A (LSD1) Inhibitor and Ruxolitinib or BET Inhibitor Against Post-MPN-sAML Blast Progenitor Cells

New Generation Chimeric Antigen Receptor T-Cell Therapy (CoupledCAR) Induces High Rate Remissions in Solid Tumor

The Embryonic Program Activated during Blast Crisis of Chronic Myelogenous Leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding and Represents a Druggable Target

A Novel BCL-2/BCL-Xl Dual Inhibitor Overcomes Ibrutinib-Resistance Conferred By the Upregulation of Integrin Pathway and BCL-Xl

Synergistic Pre-Clinical Activity of Targeted Inhibition of KDM1A and BET Proteins Against Human AML Blast Progenitor Cells

Probing Distinct Oncogene Addiction By Novel BCL-2 Inhibitors

Reversal of Chemoresistance in Leukemia Cells Using Synthetic Bisbenzylisoquinoline Derivatives

Feasibility of a Smartphone-Based Health Coaching Intervention for Patient Self-Management of Nutrition in the Post-Chemotherapy Setting

Markers of Oxidative Stress Do Not Correlate with Labile Plasma Iron Blood in Patients with Myelodysplastic Syndromes

Novel Epigenetic Modulators That Promote Fetal Hemoglobin Production for the Prevention of Sickle Cell Disease Related Complications

Shear-Dependent Fibrillogenesis of Fibronectin: Impact of Platelet Integrins and Actin Cytoskeleton

Pharmacological Inhibitors of LSD1 Promote Differentiation of Myeloid Leukemia Cells through a Mechanism Independent of Histone Demethylation

Targeting The PI3K/AKT Pathway To Inhibit Platelet Activation and Thrombus Formation

Histone H3 Methylation Mediates All- Trans -Retinoic Acid Responsiveness in Acute Myeloid Leukemia

HDAC and LSD1 Inhibitors Synergize to Induce Cell Death in Acute Leukemia Cells

Serum ceruloplasmin protein expression and activity increases in iron-deficient rats and is further enhanced by higher dietary copper intake

Clioquinol Arrests Cell Cycle at G1 Phase and Triggers Intrinsic Apoptosis In Myeloma and Leukemia Cells by Inhibiting Histone Deacetylases

Comparison of B Cell Depletion Mediated by Intravenous (IV) Rituxan® and Rituxan Given Subcutaneous (SC) In Cynomolgus Monkeys

Granulocyte Colony-Stimulating Factor (G-CSF) Stimulates Sympathetic Nervous System Activity in the Bone Marrow

Lock 'n' roll with VAP-1

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American Society of Hematology

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American Society of Hematology

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