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Journal Articles

Integrated Genomics and Functional Validation Identifies a Global Kinase Gene Signature Impacting Genome Stability in Myeloma

Subodh Kumar, PhD, Leutz Buon, Srikanth Talluri, PhD, Chengcheng Liao, MD PhD, Jialan Shi, MD PhD, Mychell Neptune, Chandraditya Chakraborty, PhD, Mehmet Kemal Samur, PhD, Rao Prabhala, Masood A. Shammas, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 363.

https://doi.org/10.1182/blood-2019-129069

Published: 2019

Journal Articles

Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML)

Liana E Gynn, BSc, Elizabeth Anderson, PhD, Gareth M Robinson, PhD, Sarah Anne Wexler, MBBS, MRCP, FRCPath, Gillian Upstill-Goddard, Christine Cox, Rhys Gareth Morgan, PhD, Jennifer E May, PhD BSc

Blood (2019) 134 (Supplement_1): 2492.

https://doi.org/10.1182/blood-2019-122891

Published: 2019

Journal Articles

Chromatin Structure Dynamics Preserve Genome Stability in Multiple Myeloma

Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Monica S. Nair, Johannes M. Waldschmidt, MD, Julia Frede, PhD MPhil, Tushara Vijaykumar, Amy Guillaumet-Adkins, PhD, Valeriya Dimitrova, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD

Blood (2019) 134 (Supplement_1): 1777.

https://doi.org/10.1182/blood-2019-127495

Published: 2019

Journal Articles

Deletions of 5q Promote Genome Instability in TP53-Mutant MDS/AML

Andreea Reilly, Stephanie Busch, B.S., Janis L. Abkowitz, MD, Pamela S. Becker, MD PhD, Sergei Doulatov, PhD

Blood (2019) 134 (Supplement_1): 1244.

https://doi.org/10.1182/blood-2019-127038

Published: 2019

Journal Articles

Interleukin-6 Adversely Impacts Genomic Stability Via Targeting Multiple Pathways in Multiple Myeloma

Chaitanya Yenumula, MD, Srikanth Talluri, PhD, Tommaso Perini, MD, Subodh Kumar, PhD, Jialan Shi, MD PhD, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 4467.

https://doi.org/10.1182/blood-2018-99-119346

Published: 2018

Journal Articles

PDZ Binding Kinase (PBK) - a Novel Gene Driving Genomic Evolution in Multiple Myeloma

Subodh Kumar, PhD, Leutz Buon, Srikanth Talluri, PhD, Jialan Shi, MD PhD, Hervé Avet-Loiseau, MD PhD, Mehmet Kemal Samur, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 4474.

https://doi.org/10.1182/blood-2018-99-119186

Published: 2018

Journal Articles

An Acquired High-Risk Chromosome Instability Phenotype in Multiple Myeloma: Jumping 1q Syndrome

Jeffery R. Sawyer, Erming Tian, PhD MBA, Brian A Walker, PhD, Christopher P. Wardell, PhD MSc, BSc, Joshua Epstein, DSc, Janet L Lukacs, Gael M. Sammartino, Clyde Bailey, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Maurizio Zangari, MD, Faith E. Davies, MD, Frits van Rhee, MD PhD, Gareth Morgan, MD

Blood (2018) 132 (Supplement 1): 4489.

https://doi.org/10.1182/blood-2018-99-115090

Published: 2018

Journal Articles

Genomic-DNA Exposed By Somatic Gene Mutations Engages the cGAS/STING Axis to License the NLRP3 Inflammasome in Myelodysplastic Syndromes

Amy F McLemore, M.S., Kathy L McGraw, PhD, Hsin-An Hou, MD PhD, Grace A Ward, BS, Alexis H Onimus, BS, Nicole D. Vincelette, PhD, Matthew A. Rodrigues, PhD, Neelkamal Chaudhary, PhD, Ling Zhang, MD, Benjamin S. Meyer, Erika A Eksioglu, PhD MS, Sheng Wei, MD, Alan F. List, MD

Blood (2018) 132 (Supplement 1): 3075.

https://doi.org/10.1182/blood-2018-99-116929

Published: 2018

Journal Articles

Immune Microenvironment Contributes to Dysregulation of Aid/Apobec Expression and Genomic Instability in Multiple Myeloma

Srikanth Talluri, PhD, Mehmet Kemal Samur, PhD, Puru Nanjappa, Chaitanya Yenumula, MD, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4333.

https://doi.org/10.1182/blood.V130.Suppl_1.4333.4333

Published: 2017

Journal Articles

Targeting Homologous Recombination Increases Cytotoxicity While Reducing Genomic Instability Induced By Melphalan in Myeloma

Subodh Kumar, PhD, Srikanth Talluri, PhD, Puru Nanjappa, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4388.

https://doi.org/10.1182/blood.V130.Suppl_1.4388.4388

Published: 2017

Journal Articles

Atypical monoblasts with micronuclei

Sylvie Bouvier, Mélanie Martin

Blood (2017) 130 (17): 1958.

https://doi.org/10.1182/blood-2017-07-795542

Published: 2017

Journal Articles

Blast Crisis in a Dish: Generation of a Blast Crisis Model in Chronic Myeloid Leukemia (CML) Using Patient-Specific Induced Pluripotent Stem Cells ( iPSC)

Gladys Telliam, Christophe Desterke, PhD, Olivier Féraud, PhD, Frank Griscelli, PharmD, PhD, Noufissa Oudrhiri, Micheline Fontaine Arnoux, Radhia Najar, PhD, Herve Acloque, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD, PhD

Blood (2016) 128 (22): 933.

https://doi.org/10.1182/blood.V128.22.933.933

Published: 2016

Journal Articles

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

Akiko Nagamachi, PhD, Yuko Ozaki, PhD, Hirotaka Matsui, MD PhD, Akinori Kanai, PhD, Toshiya Inaba, MD

Blood (2015) 126 (23): 2845.

https://doi.org/10.1182/blood.V126.23.2845.2845

Published: 2015

Journal Articles

ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma

Matteo Marchesini, Paola Storti, Yamini Ogoti, Marianna D'Anca, Luigi Nezi, Yue Wei, Hui Yang, Derrick Ong, Antonino Neri, Nicola Giuliani, MD PhD, Guillermo Garcia-Manero, MD, Ronald DePinho, Simona Colla

Blood (2014) 124 (21): 30.

https://doi.org/10.1182/blood.V124.21.30.30

Published: 2014

Journal Articles

Genomic Instability in Fanconi Anemia Results from a Combination of Chromosome Mis-Segregation in Mitosis and Unresolved Interphase DNA Damage

Donna Cerabona, Zahi Abdul Sater, Rikki Enzor, PhD, Grzegorz Nalepa, MD PhD

Blood (2014) 124 (21): 357.

https://doi.org/10.1182/blood.V124.21.357.357

Published: 2014

Journal Articles

Effects of First and Next-Generation Tyrosine Kinase Inhibitors on Telomere-Mediated Chromosomal Instability in Chronic Myeloid Leukemia Cells

Tomasz Stoklosa, MD PhD, Anna Deregowska, Joanna Drzewinska-Chanko, PhD, Joanna Barankiewicz, MD, Machnicki M Marcin, Pruszczyk Katarzyna, Maciej Wnuk, PhD

Blood (2014) 124 (21): 5510.

https://doi.org/10.1182/blood.V124.21.5510.5510

Published: 2014

Journal Articles

Biocompatibility Assessment Of DNR-Peg-PLL-PLGA Nanoparticles In Vitro and In Vivo

Baoan Chen, PHD, Professor, Liting Guo, Ran Liu, Ping Liu, undergraduate, Guohua Xia, Yonglu Wang, PHD, Xueming Li, PHD, Wei Chen

Blood (2013) 122 (21): 4920.

https://doi.org/10.1182/blood.V122.21.4920.4920

Published: 2013

Journal Articles

Cyclin D1 Maintains Mantle Cell Lymphoma Through CDK4-Independent Regulation Of DNA Replicative Checkpoints

Suchismita Mohanty, PhD, Atish Mohanty, PhD, Natalie Sandoval, MS, Victoria Bedell, Joyce Murata-Collins, PhD, Jun Wu, PhD, Anna Scuto, Dennis D. Weisenburger, MD, Vu N Ngo, PhD

Blood (2013) 122 (21): 2512.

https://doi.org/10.1182/blood.V122.21.2512.2512

Published: 2013

Journal Articles

The Tumor Suppressor APC/C Cdh1 and Its Role In Replication Stress and The Origin Of Genomic Instability

Julika Krohs, Dominik Schnerch, MD, Marie Follo, Julia Felthaus, Monika Engelhardt, MD, Ralph M. Waesch, MD

Blood (2013) 122 (21): 2489.

https://doi.org/10.1182/blood.V122.21.2489.2489

Published: 2013

Journal Articles

Aurora-A Polymorphisms in Multiple Myeloma: Implications On Chromosomal Instability

Ludmila Weiz, Suzin Choi, PhD, Niels Weinhold, PhD, Kai Neben, MD, Anthony D Ho, MD, Hartmut Goldschmidt, MD, PhD, Kari Hemminki, PhD, Alwin Krämer, MD, Marc S Raab, MD

Blood (2012) 120 (21): 3982.

https://doi.org/10.1182/blood.V120.21.3982.3982

Published: 2012

NARROW

Integrated Genomics and Functional Validation Identifies a Global Kinase Gene Signature Impacting Genome Stability in Myeloma

Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML)

Chromatin Structure Dynamics Preserve Genome Stability in Multiple Myeloma

Deletions of 5q Promote Genome Instability in TP53-Mutant MDS/AML

Interleukin-6 Adversely Impacts Genomic Stability Via Targeting Multiple Pathways in Multiple Myeloma

PDZ Binding Kinase (PBK) - a Novel Gene Driving Genomic Evolution in Multiple Myeloma

An Acquired High-Risk Chromosome Instability Phenotype in Multiple Myeloma: Jumping 1q Syndrome

Genomic-DNA Exposed By Somatic Gene Mutations Engages the cGAS/STING Axis to License the NLRP3 Inflammasome in Myelodysplastic Syndromes

Immune Microenvironment Contributes to Dysregulation of Aid/Apobec Expression and Genomic Instability in Multiple Myeloma

Targeting Homologous Recombination Increases Cytotoxicity While Reducing Genomic Instability Induced By Melphalan in Myeloma

Atypical monoblasts with micronuclei

Blast Crisis in a Dish: Generation of a Blast Crisis Model in Chronic Myeloid Leukemia (CML) Using Patient-Specific Induced Pluripotent Stem Cells ( iPSC)

Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase

ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma

Genomic Instability in Fanconi Anemia Results from a Combination of Chromosome Mis-Segregation in Mitosis and Unresolved Interphase DNA Damage

Effects of First and Next-Generation Tyrosine Kinase Inhibitors on Telomere-Mediated Chromosomal Instability in Chronic Myeloid Leukemia Cells

Biocompatibility Assessment Of DNR-Peg-PLL-PLGA Nanoparticles In Vitro and In Vivo

Cyclin D1 Maintains Mantle Cell Lymphoma Through CDK4-Independent Regulation Of DNA Replicative Checkpoints

The Tumor Suppressor APC/C Cdh1 and Its Role In Replication Stress and The Origin Of Genomic Instability

Aurora-A Polymorphisms in Multiple Myeloma: Implications On Chromosomal Instability

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American Society of Hematology

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ASH Publications

American Society of Hematology

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