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Journal Articles

Fast Onset of Action of Subcutaneously Administered Marzeptacog Alfa (Activated) Supports on-Demand Treatment in Hemophilia a Mice

Free
Frank Del Greco, MBA, Linda Neuman, MD, Howard Levy, PhD MBBChir, Jill Reckless, Tom Knudsen, PhD DVM, Grant E. Blouse, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2420.
https://doi.org/10.1182/blood-2019-128971
Published: 2019
Journal Articles

In Vitro and In Vivo Characterization of Marstacimab, an Anti-TFPI Antibody

Free
Chuenlei Parng, PhD, Macy Jin, PhD, Matthew Holsti, PhD, Susan Benard, Swapnil Rakhe, MS, Sunita R. Patel-Hett, PhD, Alison Joyce, Rob Webster, Debra D Pittman, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2391.
https://doi.org/10.1182/blood-2019-130327
Published: 2019
Journal Articles

Safety and Antithrombotic Efficacy of the Recombinant Protein C Activator AB002 (E-WE Thrombin) in End Stage Renal Disease Patients on Chronic Hemodialysis

Free
Norah G Verbout, PhD, Christina U Lorentz, PhD, Brandon D Markway, PhD, Joseph J Shatzel, MD, Erik I Tucker, PhD, Andras Gruber, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2433.
https://doi.org/10.1182/blood-2019-124999
Published: 2019
Journal Articles

A Phase 2 Study of MT-3724 to Evaluate Safety, Pharmacodynamics and Efficacy of MT-3724 for the Treatment of Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Free
Daniel O. Persky, MD, Vasile Musteata, MD PhD, Mamia Zodelava, MD, Tetiana Perekhrestenko, MD PhD, Adolfo E Diaz, MD, Troy H. Guthrie, Jr., MD, Thomas Strack, MD, Christine Burnett, Sarah Wilson, CCRA, Tara Baetz, MD FRCPC
Journal: Blood
Blood (2019) 134 (Supplement_1): 5324.
https://doi.org/10.1182/blood-2019-128604
Published: 2019
Journal Articles

Portia: A Phase 1b Study Evaluating Safety and Efficacy of Tisagenlecleucel and Pembrolizumab in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Free
Ulrich Jaeger, MD, Nina Worel, MD, Joseph P. McGuirk, DO, Peter A. Riedell, MD, Isabelle Fleury, MD, Peter Borchmann, MD, Jufen Chu, PhD, Ahmed M Abdelhady, PhD, Alessandra Forcina, MD, Lida Bubuteishvili Pacaud, MD, Edmund K. Waller, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5325.
https://doi.org/10.1182/blood-2019-129120
Published: 2019
Journal Articles

Interim Results of a First in Man Study with the Fc-Optimized FLT3 Antibody Flysyn for Treatment of Acute Myeloid Leukemia with Minimal Residual Disease

Free
Sabine Kayser, MD, Jonas S. Heitmann, MD, Daniela Dörfel, MD, Felicitas Thol, MD, Michael Heuser, MD, Melanie Märklin, PhD, Carsten Müller-Tidow, MD, Martin Steiner, Ludger Grosse-Hovest, Gundram Jung, MD, Richard F. Schlenk, MD, Helmut R. Salih, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3928.
https://doi.org/10.1182/blood-2019-125327
Published: 2019
Journal Articles

A Phase I/II Study of AZD2811 Nanoparticles (NP) As Monotherapy or in Combination in Treatment-Naïve or Relapsed/Refractory AML/MDS Patients Not Eligible for Intensive Induction Therapy

Free
William B. Donnellan, MD, Ehab L. Atallah, MD, Adam S. Asch, MD, Manish R. Patel, MD, Jay Yang, MD, Alireza Eghtedar, MD, Gautam M. Borthakur, MD, Julie Charlton, PhD, Alexander MacDonald, MSc-PhD, Anna Korzeniowska, MD, Elizabeth Sainsbury, BSc, Donald K. Strickland, MD, Suzanne Jones, PharmD, Philip Overend, MSc, Carrie A. Adelman, PhD, Giulia Fabbri, MD PhD, Jon Travers, PhD, Simon Smith, PhD, J. Elizabeth Pease, PhD, Jan Cosaert, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3919.
https://doi.org/10.1182/blood-2019-130635
Published: 2019
Journal Articles

Frontline Treatment with Ibrutinib with Rituximab (IR) Combination Is Highly Effective in Elderly (≥65 years) Patients with Mantle Cell Lymphoma (MCL) - Results from a Phase II Trial

Free
Preetesh Jain, MBBS,MDDM,PhD, Hun Ju Lee, MD, Raphael Eric Steiner, MD, F. B. Hagemeister, MD, Felipe Samaniego, MD, Jason R. Westin, MD, Loretta J. Nastoupil, MD MSc, Sairah Ahmed, MD, Swaminathan P. Iyer, MD, Jorge Enrique Romaguera, MD, Shuangtao Zhao, PhD, Krystle Nomie, PhD, Chi Young Ok, MD, Rashmi Kanagal-Shamanna, MD, Onyeka Oriabure, Guofang Xu, MD, Liang Zhang, MD PhD, Changying Jiang, PhD, Dayoung Jung, Lucy Navsaria, MB BCh BAO, Wendy Chen, Omar Moghrabi, Tayyaba Nizam, Chloe Marie McClain, Maria Badillo, Selvi Thirumurthi, David Santos, Guilin Tang, MD, Keyur Patel, MD PhD, Sattva S Neelapu, MD, Linghua Wang, PhD, Nathan H. Fowler, MD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3988.
https://doi.org/10.1182/blood-2019-125800
Published: 2019
Journal Articles

A Phase 1a/1b Trial of ST-001, a Fenretinide Phospholipid Suspension for 4-Hour Intravenous Infusion in Relapsed/Refractory T-Cell Non-Hodgkin's Lymphoma

Free
Ayad Al-Katib, MD, Timothy M. Kuzel, MD, Ralph Parchment, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4041.
https://doi.org/10.1182/blood-2019-127278
Published: 2019
Journal Articles

Phase 2 Study of E7777, a Diphtheria Toxin Fragment-Interleukin-2 Fusion Protein, in Japanese Patients with Relapsed or Refractory Peripheral and Cutaneous T-Cell Lymphoma

Free
Dai Maruyama, MD PhD, Kiyoshi Ando, Kazuhito Yamamoto, Eiji Kiyohara, MD, Yasuhito Terui, MD PhD, Noriko Fukuhara, MD PhD, Tomomitsu Miyagaki, MD PhD, Hidetsugu Kawai, MD, Yoshiki Tokura, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Tadahiko Igarashi, MD PhD, Junya Kuroda, MD PhD, Jiro Fujita, MD PhD, Toshiki Uchida, MD PhD, Takayuki Ishikawa, MD PhD, Kentaro Yonekura, MD PhD, Koji Kato, MD PhD, Tadashi Nakanishi, Kenya Nakai, Risa Matsunaga, Kensei Tobinai, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4032.
https://doi.org/10.1182/blood-2019-121723
Published: 2019
Journal Articles

Alemtuzumab as First Line Treatment in Children with Familial Lymphohistiocytosis

Free
Despina Moshous, MD PhD, Coralie Briand, MD, Martin Castelle, MD, Laurent Dupic, MD, Guillaume Morelle, MD, Wadih Abou Chahla, MD, Vincent Barlogis, MD PhD, Yves Bertrand, MD, Bénédicte Bruno, MD, Eric Jeziorski, MD PhD, Catherine Paillard, MD PhD, Pierre Simon Rohrlich, MD PhD, Jean Louis Stephan, MD PhD, Caroline Thomas, MD, Stéphanie Chhun, PharmD, PhD, Isabelle Pellier, MD PhD, Aude Marie-Cardine, MD, Mathieu Fusaro, Genevieve de Saint Basile, MD PhD, Capucine Picard, MD PhD, Caroline Elie, MD PhD, Benedicte Neven, MD PhD, Stephane Blanche, MD, Alain Fischer, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 80.
https://doi.org/10.1182/blood-2019-124477
Published: 2019
Journal Articles

TJC4, a Differentiated Anti-CD47 Antibody with Novel Epitope and RBC Sparing Properties

Free
Zhen Meng, PhD, Zhengyi Wang, PhD, Bingshi Guo, PhD, Wei Cao, PhD, Huaqiong Shen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4063.
https://doi.org/10.1182/blood-2019-122793
Published: 2019
Journal Articles

Safety and Efficacy of Propylene Glycol-Free Melphalan (Evomela) in Patients with AL Amyloidosis Undergoing Autologous Stem Cell Transplantation: Preliminary Results of a Phase II Study

Free
Shayna Sarosiek, John Mark Sloan, MD, Karen Quillen, MDMPH, Dina Brauneis, ANP, Ramon Cruz, Amanda Schulman, Salli Fennessey, Anthony Shelton, Vaishali Sanchorawala, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4578.
https://doi.org/10.1182/blood-2019-129095
Published: 2019
Journal Articles

CD39 As a Master Regulator of Pulmonary Thrombosis in Sickle Cell Disease

Free
Tomasz Brzoska, PhD, Egemen Tutuncuoglu, MSc, Stevan P. Tofovic, Edwin K. Jackson, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2266.
https://doi.org/10.1182/blood-2019-130882
Published: 2019
Journal Articles

Severe Hypophosphatemia in Patients with Cancer Following IV Iron Treatment: Results from a Large Comparative Trial

Free
Ralph V. Boccia, MD, Naomi V Dahl, PharmD, William E Strauss, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2236.
https://doi.org/10.1182/blood-2019-126149
Published: 2019
Journal Articles

Arsenic Trioxide Synergistically Enhances the Antileukemia Activity of Bcl-2 Inhibitor ABT-199 in Acute Myeloid Leukemia

Free
Sha Liu, Lin Chen, MD, Xiaojiao Wang, Ruihua Mi, Qingsong Yin, Ruihua Fan, Xudong Wei, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2555.
https://doi.org/10.1182/blood-2019-129543
Published: 2019
Journal Articles

Intravital Imaging of Bright Cyan-Fluorescent AML Model Reveals Impact of CXCR4 Inhibitor on AML and Immune Cell Dynamics

Free
Tomasz Zal, PhD, Mateusz Rytelewski, PhD, Rodrigo Jacamo, PhD, Malgorzata Anna Zal, MSc, Meenakshi Shanmugasundaram, Michael Andreeff, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2674.
https://doi.org/10.1182/blood-2019-131945
Published: 2019
Journal Articles

A Phase Ib/II Study of the Histone Methyltransferase Inhibitor Pinometostat in Combination with Azacitidine in Patients with 11q23-Rearranged Acute Myeloid Leukemia

Free
Kamal Menghrajani, MD, Sheng F Cai, MD PhD, Sean M. Devlin, PhD, Scott A. Armstrong, MD PhD, Richard Piekarz, MD PhD MS, BA, Michelle Rudek, PharmD, PhD, Martin S. Tallman, MD, Eytan M. Stein, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2655.
https://doi.org/10.1182/blood-2019-121926
Published: 2019
Journal Articles

Response-Adapted Therapy with Infusional EPOCH Chemotherapy Plus Rituximab in HIV-Associated, B-Cell Non-Hodgkin's Lymphoma

Free
Juan Carlos Ramos, MD BS, Richard F. Ambinder, MD, Joseph Sparano, MD, Jeannette Y Lee, PhD, Lawrence D Kaplan, MD, William Wachsman, MD PhD, David M. Aboulafia, MD, Ariela Noy, MD, Lee Ratner, MD PhD, David H. Henry, MD, Amy Chadburn, MD, Ethel Cesarman, MD PhD, Ronald T. Mitsuyasu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2872.
https://doi.org/10.1182/blood-2019-123558
Published: 2019
Journal Articles

Brentuximab Vedotin in Front-Line Therapy of Hodgkin Lymphoma (HL) and CD30-Expressing Peripheral T-Cell Lymphoma (PTCL) in Adults Age 60 and Above

Free
Christopher A. Yasenchak, MD, Rodolfo Bordoni, MD, Victor Yazbeck, MD, Dipti Patel-Donnelly, MD, Timothy Larson, MD, Trevor Newhook, MS, Linda Ho, Matthew Mei, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2852.
https://doi.org/10.1182/blood-2019-122968
Published: 2019